Komuro Akiyoshi 古室暁義

… Alternative Names

KOMURO Akiyoshi 古室暁義

KOMURO AKIYOSHI 古室暁義

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Researcher Number	50512274
Other IDs
Affiliation (Current)	2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 近畿大学, 医学部, 講師 2019 – 2023: 近畿大学, 医学部, 講師 2018 – 2019: 近畿大学, 医学部, 助教 2015: 近畿大学, 医学部, 助教 2012 – 2014: 東京大学, 医学(系)研究科(研究院), 研究員 2013: 東京大学, 医学(系)研究科(研究院), 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 55010:General surgery and pediatric surgery-related / Tumor biology / Tumor biology Except Principal Investigator Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator エピゲノム / 発現制御 / Histone demethylase / 乳がん / エピジェネティクス / 脳腫瘍幹細胞 / BMP / 脳腫瘍 / Super Enhancer / 転移 … More / 浸潤 / BMP4 / 骨形成因子 / 膠芽腫 / 融合遺伝子 / がん幹細胞 / TGF-βファミリーシグナル / 癌幹細胞 … More Except Principal Investigator 代謝 / 代謝異常 / マウスモデル / エピジェネティクス / 代謝制御 / がん / 組織微小環境 Less

エピゲノム制御異常による乳がん悪性化と免疫抑制性微小環境形成の網羅的な解明Principal Investigator
- Principal Investigator
  
  古室暁義
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kindai University
エピゲノム制御を介した転移性乳がん発生機構の解明と新規乳がん治療法の開発Principal Investigator
- Principal Investigator
  
  古室暁義
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kindai University
Role of histone demethylase in breast cancer progression and finding new therapeutic approaches for breast cancerPrincipal Investigator
- Principal Investigator
  
  KOMURO Akiyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kindai University
Metabolic regulation and the remodeling tissue microenvironment
- Principal Investigator
  
  Okada Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kindai University
Inhibition of the maintenance of stemness of glioma initiating cells for clinical applicationsPrincipal Investigator
- Principal Investigator
  
  KOMURO Akiyoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kinki University
  The University of Tokyo
Analysis of the maintenance of stemness of glioma initiating cellsPrincipal Investigator
- Principal Investigator
  
  KOMURO AKIYOSHI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2015 2013 2012 Other

All Journal Article Presentation Book Other

[Book] 治療の分子標的としてのTGF-βシグナル, 日本臨床 (70巻増刊号8, 通巻1031号)2012
- Author(s)
  古室暁義, 宮園浩平
- Data Source
  KAKENHI-PROJECT-24700966
[Journal Article] Deoxycytidine Kinase Inactivation Enhances Gemcitabine Resistance and Sensitizes Mitochondrial Metabolism Interference in Pancreatic Cancer2024
- Author(s)
  Dash S, Ueda T, Komuro A, Honda M, Sugisawa R, Okada H.
- Journal Title
  
  Cell Death & Disease
  
  Volume: 131 Issue: 2 Pages: 1-13
- DOI
  10.1038/s41419-024-06531-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-22K11513, KAKENHI-PROJECT-21K07135
[Journal Article] MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance2023
- Author(s)
  Dash Suman, Ueda Takeshi, Komuro Akiyoshi, Amano Hisayuki, Honda Masahiko, Kawazu Masahito, Okada Hitoshi.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: online publication Issue: 5 Pages: 444-457
- DOI
  10.1158/1541-7786.mcr-22-0554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-22K11513, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-21K07135
[Journal Article] KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility2021
- Author(s)
  Ueda Takeshi、Kanai Akinori、Komuro Akiyoshi、Amano Hisayuki、Ota Kazushige、Honda Masahiko、Kawazu Masahito、Okada Hitoshi
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 3 Issue: 12 Pages: 1020-1033
- DOI
  10.1096/fba.2021-00030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11486, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-21K06829, KAKENHI-PROJECT-21K07135, KAKENHI-PROJECT-21K12239
[Journal Article] Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin2020
- Author(s)
  Oka Naohiro、Komuro Akiyoshi、Amano Hisayuki、Dash Suman、Honda Masahiko、Ota Kazushige、Nishimura Shunji、Ueda Takeshi、Akagi Masao、Okada Hitoshi
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 8 Issue: 4
- DOI
  10.1002/prp2.632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11486, KAKENHI-PROJECT-20K07346, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-18K06941, KAKENHI-PROJECT-18K07211
[Journal Article] High fat diet triggers a reduction in body fat mass in female mice deficient for Utx demethylase2019
- Author(s)
  Ota K, Komuro A, Amano H, Kanai A, Ge K, Ueda T, Okada H
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10036-10036
- DOI
  10.1038/s41598-019-46445-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06941, KAKENHI-PROJECT-18K07211, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-17K08679
[Journal Article] 骨肉腫におけるシスプラチンと抗酸化物質によるROS産生を介した抗腫瘍効果の検討2018
- Author(s)
  岡尚宏, 天野恭志, 古室暁義, 太田一成, 上田健, 西村俊司, 岡田斉, 赤木將男
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 92 Pages: 2039-2039
- Data Source
  KAKENHI-PROJECT-18K07211
[Journal Article] TGF-b-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD202013
- Author(s)
  Kimihiro C. Kawabata, Shogo Ehata, Akiyoshi Komuro, Kengo Takeuchi and Kohei Miyazono
- Journal Title
  
  Oncogne
  
  Volume: 32 (16) Pages: 2096-2106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] 骨髄系腫瘍における NEDD 化酵素の腫瘍抑制的な役割2023
- Author(s)
  上田健、Suman Dash、本多賢彦、古室暁義、岡田斉
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] エピジェネティクス制御因子UTXの欠損によって乳がん細胞の浸潤能と肺転移能は促進する2023
- Author(s)
  古室暁義、上田健、Suman Dash、岡田斉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] 網羅的CRISPRライブラリースクリーニングによるIFNγ-PD-L1経路制御因子の同定2023
- Author(s)
  岡田斉、Suman Dash、本多賢彦、古室暁義、上田健
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] Gemcitabine-resistant PDAC cells with DCK deficiency show upregulated expression of MYC and glutamine target genes2023
- Author(s)
  Suman Dash、上田健、古室暁義、岡田斉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] 浸潤性乳がん発生におけるヒストン脱メチル化酵素UTXの役割2022
- Author(s)
  古室暁義、上田　健、岡田　斉
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] 骨髄球系細胞の形質転換におけるタンパク質NEDD化制御異常の役割2022
- Author(s)
  上田健、Suman Dash、本多賢彦、古室暁義、岡田斉
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] 遺伝子改変マウスを用いたVgll2発現量が及ぼす筋代謝への影響の解析2022
- Author(s)
  本多賢彦、Suman Dash、古室暁義、上田健、岡田斉
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] Sirt1-NAD+経路による炎症性腸疾患関連大腸がんの抑制機構の解明2021
- Author(s)
  天野恭志、上田　健、古室暁義、本多賢彦、岡田　斉
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] オンコメタボライトによる毒性を回避する機構2021
- Author(s)
  上田　健、古室暁義、天野恭志、本多賢彦、岡田　斉
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] 炎症性腸疾患関連大腸がんにおけるSirt1-NAD+経路の機能解析2021
- Author(s)
  天野恭志、上田　健、古室暁義、本多賢彦、岡田　斉
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] ヒストン脱メチル化酵素UTXの欠損による乳がん細胞の浸潤能はBET阻害剤で抑制される2021
- Author(s)
  古室暁義、上田　健、岡田　斉
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06829
[Presentation] ヒストン脱メチル化酵素KDM6Aの機能欠損は乳がんの悪性化と転移を促進する2020
- Author(s)
  古室暁義
- Organizer
  第24回　日本がん分子標的治療学会学術集会（10月6-8日）
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] ヒストン脱メチル化酵素KDM6Aの機能欠損は乳がんの増殖と転移を促進する2020
- Author(s)
  古室暁義, 上田　健, 天野恭志, 岡田　斉
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] アスコルビン酸は骨肉腫細胞へのシスプラチン感受性を増強する2020
- Author(s)
  上田　健、古室暁義、天野恭志、岡田　斉
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] ヒストン脱メチル化酵素UTXの機能阻害による乳がん悪性化への影響2020
- Author(s)
  古室暁義、上田　健、岡田　斉
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] ヒストン脱メチル化酵素KDM6Aの機能阻害による乳がんの悪性化への影響2020
- Author(s)
  古室暁義
- Organizer
  第79回　日本癌学会学術総会（10月1-16日）
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] Sirt1-NAD+経路による炎症性腸疾患関連大腸がんの抑制機構の解明2020
- Author(s)
  天野恭志、上田　健、古室暁義、岡田　斉
- Organizer
  第93回日本生化学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Sirt1-NAD+経路による炎症性腸疾患関連大腸がんの抑制機構の解明2020
- Author(s)
  天野恭志、上田　健、古室暁義、岡田　斉
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] 乳がん悪性化におけるヒストン脱メチル化酵素の役割2019
- Author(s)
  古室暁義, 上田　健, 天野恭志, 岡田　斉
- Organizer
  第23回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Utx欠損は高脂肪食により誘導される肥満を雌マウス特異的に抑制する2019
- Author(s)
  岡田　斉, 古室暁義, 天野恭志, 上田　健
- Organizer
  第48回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] 乳がん悪性化におけるヒストン脱メチル化酵素の役割2019
- Author(s)
  古室暁義
- Organizer
  第23回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] Inhibition of histone demethylase KDM6A promotes breast cancer progression2019
- Author(s)
  Akiyoshi Komuro, Takeshi Ueda, Hitoshi Okada
- Organizer
  第78回　日本癌学術総会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Sirt1-NAD+経路による炎症性腸疾患の抑制機構の解明2019
- Author(s)
  天野恭志, 上田　健, 古室暁義, 岡田　斉
- Organizer
  第92回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] 8;21転座急性骨髄性白血病におけるエピゲノム調節因子の役割2019
- Author(s)
  上田　健, 金井昭教, 古室暁義, 天野恭志, 岡田　斉
- Organizer
  第92回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Sirt1-NAD+経路による炎症性腸疾患関連大腸がんの抑制機構の解明2019
- Author(s)
  天野恭志, 上田　健, 古室暁義, 岡田　斉
- Organizer
  第23回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Inhibition of histone demethylase KDM6A promotes breast cancer progression2019
- Author(s)
  古室暁義
- Organizer
  第78回　日本癌学術総会
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] 急性骨髄性白血病におけるエピゲノム調節因子の役割2019
- Author(s)
  上田　健, 金井昭教, 古室暁義, 天野恭志, 岡田　斉
- Organizer
  第23回　日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Effect of inhibition of histone demethylase KDM6A on breast cancer development2018
- Author(s)
  Akiyoshi Komuro, Takeshi Ueda, Hitoshi Okada
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] 乳がん悪性化におけるヒストン脱メチル化酵素KDM6Aの役割2018
- Author(s)
  古室暁義, 上田　健, 天野恭志, 岡田　斉
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] ヒストン脱メチル化酵素Utxによる脂質代謝制御の解明2018
- Author(s)
  太田一成、古室暁義、上田健、天野恭志、岡田斉
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] Effect of inhibition of histone demethylase KDM6A on breast cancer development2018
- Author(s)
  古室暁義
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] 乳がん悪性化におけるヒストン脱メチル化酵素KDM6Aの役割2018
- Author(s)
  古室暁義
- Organizer
  第22回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-18K07211
[Presentation] Role of histone demethylase KDM4B in acute myeloid leukemia2018
- Author(s)
  Takeshi Ueda, Akinori Kanai, Kazushige Ota, Akiyoshi Komuro, Hisayuki Amano, Naohiro Oka, Hitoshi Okada
- Organizer
  第80回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06941
[Presentation] 膠芽腫における新規融合遺伝子 HMGA2-EGFR の同定2015
- Author(s)
  古室暁義, 岩田要, 曽田学, 磯谷一暢, 鈴木啓道, Melissa Ranjit, 稲生靖, 藤堂具紀, 油谷浩幸, 夏目敦至, 武笠晃丈, 斉藤延人, 間野博行, 宮園浩平, 鯉沼代造
- Organizer
  分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830067
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Satoshi Sakai, Erna Raja, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Caname Iwata, Daizo Koinuma, Kohei Miyazono
- Organizer
  TGF-βファミリーシグナル国際共同研究拠点第3回国際シンポジウム
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP signaling suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Caname Iwata, Daizo Koinuma, Kohei Miyazono
- Organizer
  FASEB Science Research Conference "TGF-β Superfamily: Signaling in Development & Disease"
- Place of Presentation
  Colorado (USA)
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP signaling suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Satoshi Sakai, Erna Raja, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Caname Iwata, Daizo Koinuma, Kohei Miyazono
- Organizer
  TGF-βファミリーシグナル　国際共同研究拠点　第3回国際シンポジウム
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Hiroaki Ikushima, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Daizo Koinuma, Kohei Miyazono
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Hyatt Regency Maui, Maui, HI, USA
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Hiroaki Ikushima, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Daizo Koinuma, Kohei Miyazono
- Organizer
  Ninth AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui (USA)
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2013
- Author(s)
  Akiyoshi Komuro, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Caname Iwata, Daizo Koinuma, Kohei Miyazono
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2012
- Author(s)
  Akiyoshi Komuro, Hiroaki Ikushima, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Daizo Koinuma, Kohei Miyazono
- Organizer
  国際癌化学診療シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties2012
- Author(s)
  Akiyoshi Komuro, Hiroaki Ikushima, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Daizo Koinuma, Kohei Miyazono
- Organizer
  国際癌化学診療シンポジウム
- Place of Presentation
  日本科学未来館　（東京都）
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] 骨形成因子（BMP）4による膠芽腫腫瘍形成細胞の治療効果の検討2012
- Author(s)
  古室暁義, 生島弘彬, 稲生靖, 藤堂具紀, 渡部徹郎, 鯉沼代造, 宮園浩平
- Organizer
  第19回BMP研究会
- Place of Presentation
  慶応大学医学部信濃町キャンパス　（東京都）
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] 骨形成因子(BMP)4による膠芽腫腫瘍形成細胞の治療効果の検討2012
- Author(s)
  古室暁義, 生島弘彬, 稲生靖, 藤堂具紀, 渡部徹郎, 鯉沼代造, 宮園浩平
- Organizer
  第19回BMP研究会
- Place of Presentation
  東京
- Year and Date
  2012-07-22
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] Glioma Cancer Initiating Cell を標的としたTGF-βシグナル阻害剤とBMP4の併用治療効果の検討2012
- Author(s)
  古室暁義 , 生島弘彬, 江幡正悟, 渡部徹郎, 鯉沼代造, 稲生靖, 藤堂具紀, 宮園浩平
- Organizer
  第16回日本がん分子標的治療学会学術集会
- Place of Presentation
  西日本総合展示場　AIM3F （福岡県）
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] Glioma Cancer Initiating Cellを標的としたTGF-βシグナル阻害剤とBMP4の併用治療効果の検討2012
- Author(s)
  古室暁義, 生島弘彬, 江幡正悟, 渡部徹郎, 鯉沼代造, 稲生靖, 藤堂具紀, 宮園浩平
- Organizer
  第16回日本がん分子標的治療学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] BMP signaling suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties
- Author(s)
  Akiyoshi Komuro, Satoshi Sakai, Yasushi Ino, Tomoki Todo, Nobuhito Saito, Tetsuro Watabe, Caname Iwata, Daizo Koinuma, Kohei Miyazono
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24700966
[Presentation] Identification of a novel fusion gene, HMGA2-EGFR in glioblastoma
- Author(s)
  Akiyoshi Komuro, Caname Iwata, Manabu Soda, Kazunobu Isogaya, Yasushi Ino, Tomoki Todo, Hiroyuki Aburatani, Atsushi Natsume, Akitake Mukasa, Nobuhito Saito, Hiroyuki Mano, Kohei Miyazono, Daizo Koinuma
- Organizer
  Joint international symposium on TGF-β family and cancer Signal network in tumor microenvironment
- Place of Presentation
  International congress center ‘Epochal Tsukuba’ (Tsukuba Ibaraki)
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-26830067
[]
[]
[]

1. Okada Hitoshi (20280620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 天野恭志 (20549331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 上田健 (60585149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 太田一成 (70589928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. HONDA Masahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Komuro Akiyoshi 古室 暁義

KOMURO Akiyoshi 古室 暁義

KOMURO AKIYOSHI 古室 暁義

Research Projects

Research Products

Co-Researchers

エピゲノム制御異常による乳がん悪性化と免疫抑制性微小環境形成の網羅的な解明Principal Investigator

Principal Investigator

Project Period (FY)

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エピゲノム制御を介した転移性乳がん発生機構の解明と新規乳がん治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Role of histone demethylase in breast cancer progression and finding new therapeutic approaches for breast cancerPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Metabolic regulation and the remodeling tissue microenvironment

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Inhibition of the maintenance of stemness of glioma initiating cells for clinical applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Analysis of the maintenance of stemness of glioma initiating cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 治療の分子標的としてのTGF-βシグナル, 日本臨床 (70巻増刊号8, 通巻1031号)2012

Author(s)

Data Source

[Journal Article] Deoxycytidine Kinase Inactivation Enhances Gemcitabine Resistance and Sensitizes Mitochondrial Metabolism Interference in Pancreatic Cancer2024

Author(s)

Journal Title

DOI

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[Journal Article] MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance2023

Author(s)

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DOI

Data Source

[Journal Article] KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility2021

Author(s)

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[Journal Article] Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin2020

Author(s)

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[Journal Article] High fat diet triggers a reduction in body fat mass in female mice deficient for Utx demethylase2019

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[Journal Article] 骨肉腫におけるシスプラチンと抗酸化物質によるROS産生を介した抗腫瘍効果の検討2018

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[Journal Article] TGF-b-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD202013

Author(s)

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[Presentation] 骨髄系腫瘍における NEDD 化酵素の腫瘍抑制的な役割2023

Author(s)

Komuro Akiyoshi 古室暁義

KOMURO Akiyoshi 古室暁義

KOMURO AKIYOSHI 古室暁義