OKAMOTO Yoshinori 岡本誉士典

… Alternative Names

Okamoto Yoshinori 岡本誉士典

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Researcher Number	50512323
Other IDs
Affiliation (Current)	2025: 名城大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 名城大学, 薬学部, 准教授 2009 – 2015: Meijo University, 薬学部, 助教 2008: 立命館大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Environmental pharmacy / Basic Section 63030:Chemical substance influence on environment-related / Risk sciences of radiation and chemicals Except Principal Investigator Physical pharmacy / Chemical pharmacy / Biological Sciences / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 幹細胞発がん / 乳がん / 発がん / ゲノム編集 / メタボロミクス / エストロゲン / リゾホスファチジン酸 / 脂質メディエーター / メタボローム / DNA損傷 … More / シクロブタン型ピリミジンダイマー / 未分化因子 / 配列特異性 / ＤＮＡ損傷 / LC/MS/MS / 脱メチル化 / 受精卵 / 未分化マーカー / ゲノム修飾 / 紫外線照射 / マウス胚性幹細胞 / 未分化 / 異物代謝 / 多環芳香族炭化水素 / 幹細胞 / 増殖抑制 / 未分化状態 / DNA 付加体 / 化学発がん物質 / DNA付加体 / 酸化ストレス / 遺伝子損傷 / 性ホルモン / ES細胞 … More Except Principal Investigator 生殖細胞分化 / ES細胞 / 細胞内分布 / 抗がん作用 / 細胞内還元 / 細胞障害 / シスプラチン耐性 / ヒト卵巣がん / タイムラプス解析 / 薬物耐性 / グルタチオン / 酸化ストレス / 活性酸素種 / 白金４価錯体 / Lapachol / 肥厚性瘢痕由来線維芽細胞 / クマリン / フラボノイド / Citrus tachibana / 機能性成分 / マイヤーレモン / ロテノイド誘導体 / ケイヒ酸誘導体 / カルバゾールアルカロイド / NO 産生抑制活性 / カルバゾールキノン誘導体 / 細胞毒性 / ベンゾフェノン / ビフェニル誘導体 / キノリン-2,4-ジオンアルカロイド / ES・iPS細胞分化 / NO産生抑制活性 / 抗酸化活性 / がん細胞増殖抑制活性 / ヒスタミン放出抑制活性 / アポトーシス誘導活性 / 天然資源 / in vitro / 遺伝子発現 / Non-human primate / 環境分析 / Bacベクター / 生殖細胞遺伝子発現 / 細胞分化 / 内分泌撹乱物質 Less

Identification of novel carcinogenic mechanisms for mammary gland induced by lipid-mediatorsPrincipal Investigator
- Principal Investigator
  
  Okamoto Yoshinori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Meijo University
Determination of intra-cellular dynamics of platinum(IV) complexes using imaging technique
- Principal Investigator
  
  Kojima Nakao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science
  Meijo University
A picture of whole DNA modification induced by carcinogens: Whole-genome analysis for sequence specificity and vulnerabilityPrincipal Investigator
- Principal Investigator
  
  OKAMOTO YOSHINORI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Meijo University
Research on active compounds from natural resources affecting the differentiation of ES and iPS cells
- Principal Investigator
  
  ITO CHIHIRO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Meijo University
Determination of carcinogenic me chanisms in stem cells using ES/iPS cellsPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Yoshinori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Meijo University
Non-human Primate ES細胞の生殖細胞への分化
- Principal Investigator
  
  高田達之
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ritsumeikan University
Simulation and analysis of stem cell-carcinogenesis induced by chemical carcinogens using murine embryonic stem cellPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Yoshinori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Environmental pharmacy
- Research Institution
  Meijo University
Validation system of chemicals using BAC vector transfected ES cells
- Principal Investigator
  
  TAKADA Tatsuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ritsumeikan University

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All Journal Article Presentation Patent

[Journal Article] Less Carcinogenic Chlorinated Estrogens Applicable to Hormone Replacement Therapy2021
- Author(s)
  Okamoto Yoshinori、Jinno Hideto、Itoh Shinji、Shibutani Shinya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 13 Pages: 7222-7222
- DOI
  10.3390/ijms22137222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12186
[Journal Article] DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry2016
- Author(s)
  Yoshinori Okamoto, Naoko Yoshida, Toru Suzuki, Nobuhiro Shimozawa, Maki Asami, Tomonari Matsuda, Nakao Kojima, Anthony C. F. Perry & Tatsuyuki Takada
- Journal Title
  
  Scientific Reports
  
  Volume: 該当しない Issue: 1 Pages: 19134-19134
- DOI
  10.1038/srep19134
- NAID
  120005822766
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14440, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-25550036
[Journal Article] Thiol-mediated multiple mechanisms centered on selenodiglutathione determine selenium cytotoxicity against MCF-7 cancer cells.2015
- Author(s)
  Tobe T., Ueda K., Ando M., Okamoto Y., Kojima N.
- Journal Title
  
  J. Biol. Inorg. Chem.
  
  Volume: NA
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460047
[Journal Article] Oral administration of Brazilian propolis exerts estrogenic effect in ovariectomized rats2015
- Author(s)
  Okamoto Y, Tobe T, Ueda K, Takada T, Kojima N
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 40 Issue: 2 Pages: 235-242
- DOI
  10.2131/jts.40.235
- NAID
  130004904040
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23651248, KAKENHI-PROJECT-25550036
[Journal Article] Oral administration of Brazilian propolis exerts estrogenic effect in ovariectomized rats.2015
- Author(s)
  Okamoto Y., Tobe T., Ueda K., Takada T., Kojima N.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: NA
- NAID
  130004904040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460047
[Journal Article] Thiol-mediated multiple mechanisms centered on selenodiglutathione determine selenium cytotoxicity against MCF-7 cancer cells.2015
- Author(s)
  Tobe T., Ueda K., Ando M., Okamoto Y., Kojima N.
- Journal Title
  
  J. Biol. Inorg. Chem.
  
  Volume: NA Issue: 4 Pages: 687-694
- DOI
  10.1007/s00775-015-1254-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25550036
[Journal Article] Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes.2014
- Author(s)
  Ueda K., Makino R., Tobe T., Okamoto Y., Kojima N.
- Journal Title
  
  Fund. Toxicol. Sci.
  
  Volume: 1 Pages: 269-280
- NAID
  130005083332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460047
[Journal Article] Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes.2014
- Author(s)
  Ueda K., Makino R., Tobe T., Okamoto Y., Kojima N.
- Journal Title
  
  Fund. Toxicol. Sci.
  
  Volume: 1 Pages: 73-79
- NAID
  130005083332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25550036
[Journal Article] PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.2014
- Author(s)
  Okashita, N., Kumaki, Y., Ebi, K., Nishi, M., Okamoto, Y., Nakayama, M., Hashimoto, S., Nakamura, T., Sugasawa, K., Kojima, N., Takada, T., Okano, M. and Seki, Y.
- Journal Title
  
  Development
  
  Volume: 141 Issue: 2 Pages: 269-280
- DOI
  10.1242/dev.099622
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116008, KAKENHI-PROJECT-23651248, KAKENHI-PROJECT-24241019, KAKENHI-PROJECT-24681040, KAKENHI-PROJECT-25550036
[Journal Article] Neural Differentiation of Pluripotent Stem Cells and Application for Metal-induced Neural Toxicity Study2014
- Author(s)
  Taniguchi Y., Tobe T., Hayami H., Okamoto Y., Ueda K., Takada T., Kojima N.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 134 Issue: 7 Pages: 793-795
- DOI
  10.1248/yakushi.14-00017-3
- NAID
  130004756445
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2014-07-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460047, KAKENHI-PROJECT-25550036
[Journal Article] Roles of glutathione-mediated metabolites in the anti-tumor effects of selenium2014
- Author(s)
  Takao Tobe, Koji Ueda, Yoshinori Okamoto, Motozumi Ando, Hiroyuki Nishida, Kazuo Ito, Nakao Kojima
- Journal Title
  
  J. Res. Inst. Meijo Univ.
  
  Volume: 13
- NAID
  40020207659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550036
[Journal Article] A simple and convenient synthesis of a stable isotope-labeled 5-hydroxymehtyl-2’-deoxycytidine, the sixth base in mammalian DNA2014
- Author(s)
  Takao Tobe，Yoshinori Okamoto，Tatsuyuki Takada，Nakao Kojima
- Journal Title
  
  J. Res. Inst. Meijo Univ.
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550036
[Journal Article] Induction of the anticancer effects of cisplatin platinum(IV) derivatives against cisplatin-resistant human ovarian cancer cells.2013
- Author(s)
  Okamoto Y., Nakai T., Ando M., Ueda K., Kojima N.
- Journal Title
  
  J. Res. Inst. Meijo Univ.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Effects of genistein, kaempferol and daidzein on neuraldifferentiation of mouse embryonic stem cells.2013
- Author(s)
  Okamoto Y., Ushida M., Taniguchi Y., Takada T., Kojima N.
- Journal Title
  
  J. Res. Inst. Meijo Univ.
- NAID
  40020217494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Manganese neurotoxicity: Interplay with iron in catecholaminergic oxidative stress.2013
- Author(s)
  Ueda K., Ando M., Okamoto Y., Kojima N.
- Journal Title
  
  J. Res. Inst. Meijo Univ.
- NAID
  40020217436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Induction of the anticancer effects of cisplatin platinum(IV) derivatives against cisplatin-resistant human ovarian cancer cells.2013
- Author(s)
  Yoshinori Okamoto, Tsuyoshi Nakai, Motozumi Ando, Nakao Kojima
- Journal Title
  
  J. Res. Inst. Meijo Univ.
  
  Volume: 12 Pages: 35-41
- Data Source
  KAKENHI-PROJECT-25460047
[Journal Article] Anti-breast cancer potential of daidzein in rodents.2012
- Author(s)
  Liu X., Suzuki N., Laxmi Y.R.S., Okamoto Y., Shibutani S.
- Journal Title
  
  Life Sci.
  
  Volume: 91 Pages: 415-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Transesterification in the microbial degradation of phthalate esters2011
- Author(s)
  Okamoto Y., Toda C., Ueda K., Hashizume K., Kojima N.
- Journal Title
  
  J.Health Sci.
  
  Volume: 57 Pages: 293-299
- NAID
  130000800091
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028021
[Journal Article] Transesterification in the microbial degradation of phthalate esters.2011
- Author(s)
  Okamoto Y., Toda C., Ueda K., Hashizume K., Kojima N.
- Journal Title
  
  J.Health Sci.
  
  Volume: (in press(掲載確定))
- NAID
  130000800091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen2011
- Author(s)
  Yoshinori Okamoto, 他8名
- Journal Title
  
  Int.J.Cancer
  
  Volume: 128 Pages: 974-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen2011
- Author(s)
  Suzuki N., Liu X., Laxmi Y.R.S.Okamoto K., Kim H.J., Zhang G., Chen J.J., Okamoto Y., Shibutani S.
- Journal Title
  
  Int.J.Cancer 128
  
  Pages: 974-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Different mechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro.2011
- Author(s)
  Nishino Y., Ando M., Makino R., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Neurotox. Res.
  
  Volume: 20 Pages: 84-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen.2011
- Author(s)
  Suzuki N., Liu X., Laxmi Y.R.S., Okamoto K., Kim H.J., Zhang G., Chen J.J., Okamoto Y., Shibutani S.
- Journal Title
  
  Int.J.Cancer 128
  
  Pages: 974-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Different mechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro2011
- Author(s)
  Nishino Y., Ando M., Makino R., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Neurotox.Res.
  
  Volume: 20 Pages: 84-92
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028021
[Journal Article] Combined effects of manganese, iron, copper, and dopamine on oxidative DNA damage2011
- Author(s)
  Yoshinori Okamoto, 他3名
- Journal Title
  
  J.Health Sci.
  
  Volume: 57 Pages: 204-209
- NAID
  130000663122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Different mechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro.2011
- Author(s)
  Nishino Y., Ando M., Makino R.,Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Neurotox.Res.
  
  Volume: (in press(掲載確定))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Modulation of oxidative DNA damage and DNA-crosslink formation induced by cis-diammine-tetrachloro-platinum(IV) in the presence of endogenous reductants.2011
- Author(s)
  Nakai T., Ando M., Okamoto Y., Ueda K., Kojima N.
- Journal Title
  
  J.Inorg. Biochem. 105
  
  Pages: 1-5
- NAID
  130007003176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Transesterification in the microbial degradation of phthalate esters.2011
- Author(s)
  Okamoto Y., Toda C., Ueda K., Hashizume K., Kojima N.
- Journal Title
  
  J. Health Sci.
  
  Volume: 57 Pages: 293-299
- NAID
  130000800091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] Transesterification in the microbial degradation of phthalate esters.2011
- Author(s)
  Okamoto Y., Toda C., Ueda K., Hashizume K., Kojima N.
- Journal Title
  
  J.Health Sci. 57
  
  Pages: 293-299
- NAID
  130000800091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Combined effects of manganese, iron, copper, and dopamine on oxidative DNA damage.2011
- Author(s)
  Ando M., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  J.Health Sci. 57
  
  Pages: 204-209
- NAID
  130000663122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Modulation of oxidative DNA damage and DNA-crosslink formation induced by cis-diammine-tetrachloro-platinum(IV) in the presence of endogenous reductants2011
- Author(s)
  Yoshinori Okamoto, 他5名
- Journal Title
  
  J.Inorg.Biochem.
  
  Volume: 105 Pages: 1-5
- NAID
  130007003176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen2011
- Author(s)
  Suzuki N., Liu X., Laxmi Y.R.S., Okamoto K., Kim H.J., Zhang G., Chen J.J., Okamoto Y., Shibutani S.
- Journal Title
  
  Int.J.Cancer 128, 974-982
  
  Volume: 128 Pages: 974-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Combined effects of manganese, iron, copper, and dopamine on oxidative DNA damage2011
- Author(s)
  Ando M., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  J.Health Sci.
  
  Volume: (in press(掲載確定))
- NAID
  130000663122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Preparation of oligoselenodiglutathiones and their suppressive effects on oxidative DNA damage induced by catechol and copper.2011
- Author(s)
  Yoshinori Okamoto, 他5名
- Journal Title
  
  J.Health Sci.
  
  Volume: 57 Pages: 72-77
- NAID
  130000425125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] oligoselenodiglutathiones and their suppressive effects on oxidative DNA damage induced by catechol and copper2011
- Author(s)
  Ando M., Nishida H., Ueda K., Itoh K., Okamoto Y., Kojima N.
- Journal Title
  
  J.Health Sci.57, 72-77
  
  Volume: 57 Pages: 72-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Preparation of oligoselenodiglutathiones and their suppressive effects on oxidative DNAdamage induced by catechol and copper.2011
- Author(s)
  Ando M., Nishida H., Ueda K., Itoh K., Okamoto Y., Kojima N.
- Journal Title
  
  J.Health Sci. 57
  
  Pages: 72-77
- NAID
  130000425125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Differentmechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro.2011
- Author(s)
  Nishino Y., Ando M., Makino R., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Neurotox. Res. 20
  
  Pages: 84-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Different mechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro2011
- Author(s)
  Yoshinori Okamoto, 他3名
- Journal Title
  
  Neurotox.Res.
  
  Volume: 20 Pages: 84-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Potential risks of phathalate esters: Acquisition of endocrine-disrupting activity during environmental and metabolic processing.2011
- Author(s)
  Okamoto Y., Ueda K., Kojima N.
- Journal Title
  
  J. Health Sci.
  
  Volume: 57 Pages: 497-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790162
[Journal Article] oligoselenodiglutathiones and their suppressive effects on oxidative DNA damage induced by catechol and copper2011
- Author(s)
  Ando M., Nishida H., Ueda K., Itoh K., Okamoto Y., Kojima N
- Journal Title
  
  J.Health Sci. 57
  
  Pages: 72-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Transesterification in the microbial degradation of phthalate esters2011
- Author(s)
  Yoshinori Okamoto, 他4名
- Journal Title
  
  J.Health Sci.
  
  Volume: (未定 in press)
- NAID
  130000800091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Equine estrogen-induced mammary tumors in rats.2010
- Author(s)
  Yoshinori Okamoto, 他7名
- Journal Title
  
  Toxicol.Lett.
  
  Volume: 193 Pages: 224-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Equine estrogen-induced mammary tumors in rats2010
- Author(s)
  Okamoto Y, Liu X, Suzuki N, Okamoto K, Kim HJ, Laxmi YR, Sayama K, Shibutani S.
- Journal Title
  
  Toxicol Lett. 193
  
  Pages: 224-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Production of polyselenodipenicillamines, unique selenium compounds2010
- Author(s)
  Nishida H., Ando M., Itoh K., Ueda K., Nishida Y., Okamoto Y., Toda C., Kojima N.
- Journal Title
  
  Chem.Pharm.Bull. 58
  
  Pages: 957-960
- NAID
  130000299793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Carbonyl side-chain of catechol compounds is a key structure for the suppression of copper-associated oxidative DNA damage in vitro.2010
- Author(s)
  Ando M., Nishida H., Nishino Y., Ohbayashi M., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Toxicol. Lett. 199
  
  Pages: 213-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Penicillamine selenotrisulfide suppressed DNA strand breaks and oxidative DNA damage in vitro.2010
- Author(s)
  Ando M., Nishida H., Itoh K., Okamoto Y., Ueda K., Kojima N.
- Journal Title
  
  J.Res.Inst.Meijo Univ. 9
  
  Pages: 27-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Equine estrogen-induced mammary tumors in rats.2010
- Author(s)
  Okamoto Y., Liu X., Suzuki N., Okamoto K., Kim H.J., Laxmi Y.R.S., Sayama K., Shibutani S.
- Journal Title
  
  Toxicol. Lett. 193
  
  Pages: 224-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Equine estrogen-induced mammary tumors in rats2010
- Author(s)
  Okamoto Y, Liu X, Suzuki N, Okamoto K, Kim HJ, Laxmi YR, Sayama K, Shibutani S.
- Journal Title
  
  Toxicol Lett. 193
  
  Pages: 224-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028021
[Journal Article] Production of polyselenodipenicillamines, unique selenium compounds.2010
- Author(s)
  Yoshinori Okamoto, 他7名
- Journal Title
  
  Chem.Pharm.Bull.
  
  Volume: 58 Pages: 957-960
- NAID
  130000299793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Production of polyselenodipenicillamines, unique selenium compounds.2010
- Author(s)
  Nishida H., Ando M., Itoh K., Ueda K., Nishida Y., Okamoto Y., Toda C., Kojima N.
- Journal Title
  
  Chem. Pharm. Bull. 58
  
  Pages: 957-960
- NAID
  130000299793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions.2010
- Author(s)
  Yoshinori Okamoto, 他9名
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127 Pages: 1718-1726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions2010
- Author(s)
  Laxmi YR, Liu X, Suzuki N, Kim SY, Okamoto K, Kim HJ, Zhang G, Chen JJ, Okamoto Y, Shibutani S.
- Journal Title
  
  Int J Cancer (In press(掲載決定))
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028021
[Journal Article] Production of polyselenodipenicillamines, unique selenium compounds2010
- Author(s)
  Nishida H., Ando M., Itoh K., Ueda K., Nishida Y., Okamoto Y., Toda C., Kojima N.
- Journal Title
  
  Chem.Pharm.Bull.
  
  Volume: 58 Pages: 957-960
- NAID
  130000299793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Carbonyl side-chain of catechol compounds is a key structure for the suppression of copper-associated oxidative DNA damage in vitro2010
- Author(s)
  Ando M., Nishida H., Nishino Y., Ohbayashi M., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Toxicol.Lett. 199
  
  Pages: 213-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions2010
- Author(s)
  Yoshinori Okamoto, 他9名
- Journal Title
  
  Int.J.Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Carbonyl side-chain of catechol compounds is a key structure for the suppression of copper-associated oxidative DNA damage in vitro2010
- Author(s)
  Yoshinori Okamoto, 他6名
- Journal Title
  
  Toxicol.Lett.
  
  Volume: 199 Pages: 213-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Penicillamine selenotrisulfide suppressed DNA strand breaks and oxidative DNA damage in vitro.2010
- Author(s)
  Yoshinori Okamoto, 他5名
- Journal Title
  
  J.Res.Inst.Meijo Univ.
  
  Volume: 9 Pages: 27-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions.2010
- Author(s)
  Laxmi Y.R.S., Liu X., Suzuki N., Kim S.Y., Okamoto K., Kim H.J., Zhang G., Chen J.J., Okamoto Y., Shibutani S.
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1718-1726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Anti- breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions2010
- Author(s)
  Laxmi YR, Liu X, Suzuki N, Kim SY, Okamoto K, Kim HJ, Zhang G, Chen JJ, Okamoto Y, Shibutani S.
- Journal Title
  
  Int J Cancer (In press(掲載決定))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions2010
- Author(s)
  Laxmi YR, Liu X, Suzuki N, Kim SY, Okamoto K, Kim HJ, Zhang G, Chen JJ, Okamoto Y, Shibutani S.
- Journal Title
  
  Int J Cancer 127
  
  Pages: 1718-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Equine estrogen-induced mammary tumors in rats2010
- Author(s)
  Yoshinori Okamoto, 他7名
- Journal Title
  
  Toxicol.Lett. 193
  
  Pages: 224-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890279
[Journal Article] Carbonyl side-chain of catechol compounds is a key structure for the suppression of copper-associated oxidative DNA damage in vitro2010
- Author(s)
  Ando M., Nishida H., Nishino Y., Ohbayashi M., Ueda K., Okamoto Y., Kojima N.
- Journal Title
  
  Toxicol.Lett.
  
  Volume: 199 Pages: 213-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Oxidative DNA damage in XPC-knockout and its wild mice treated with equine estrogen.2008
- Author(s)
  Okamoto Y. Chou P.H, Kim S.Y., Suzuki N, Laxmi Y. R. S., Okamoto K, Liu X, Matsuda T, Shibutani S
- Journal Title
  
  Chem.Res.Toxicol 21
  
  Pages: 1120-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Oxidative DNA damage in XPC-knockout and its wild mice treated with equine estrogen.2008
- Author(s)
  Okamoto Y. Chou P. H, Kim S. Y., Suzuki N, Laxmi Y. R. S., Okamoto K, Liu X, Matsuda T, Shibutani S
- Journal Title
  
  Chera. Res. Toxicol 21
  
  Pages: 1120-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate2008
- Author(s)
  Okamoto Y, Liu X, Suzuki N, Okamoto K, Sekimoto M, Laxmi Y.R.S., Shibutani S
- Journal Title
  
  Int.J.Cancer 112
  
  Pages: 2142-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate2008
- Author(s)
  Okamoto Y, Liu X, Suzuki N, Okamoto K, Sekimoto M, Laxmi Y. R. S., Shibutani S
- Journal Title
  
  Int. J. Cancer 112
  
  Pages: 2142-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage2008
- Author(s)
  Okamoto Y, T. Hayashi T, Matsunami S, Ueda K, Kojima N.
- Journal Title
  
  Chem.Res.Toxicol. 21
  
  Pages: 1594-1599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Journal Article] Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage2008
- Author(s)
  Okamoto Y, T. Hayashi T, Matsunami S, Ueda K, Kojima N.
- Journal Title
  
  Chem. Res. Toxicol. 21
  
  Pages: 1594-1599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510063
[Patent] ハロゲン化エストロゲンを用いたエストロゲン補充療法のためのエストロゲン製剤2020
- Inventor(s)
  神野透人、岡本誉士典、渋谷眞也、伊藤慎二
- Industrial Property Rights Holder
  名城大学、渋谷眞也、伊藤慎二
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2020-111568
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K12186
[Patent] ハロゲン化エストロゲンを用いたエストロゲン補充療法のためのエストロゲン製剤2020
- Inventor(s)
  渋谷眞也、伊藤慎二、神野透人、岡本誉士典
- Industrial Property Rights Holder
  渋谷眞也、伊藤慎二、学校法人名城大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2022
- Data Source
  KAKENHI-PROJECT-20K12186
[Patent] dC、mdC、及び/又はhmdCを測定する方法2012
- Inventor(s)
  小嶋仲夫,岡本誉士典,高田達之
- Industrial Property Rights Holder
  名城大学,立命館大学(共同出願)
- Acquisition Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-23790162
[Patent] 遺伝子中のメチル化塩基の迅速・超高感度分析法2011
- Inventor(s)
  高田達之、小嶋仲夫、岡本誉士典
- Industrial Property Rights Holder
  高田達之、小嶋仲夫、岡本誉士典
- Industrial Property Number
  2011-102765
- Filing Date
  2011-05-02
- Data Source
  KAKENHI-PUBLICLY-21028021
[Patent] 名遺伝子中のメチル化塩基の迅速・超高感度分析法2011
- Inventor(s)
  高田達之、小嶋仲夫、岡本誉士典
- Industrial Property Rights Holder
  立命館大学、名城大学
- Industrial Property Number
  2011-102765
- Filing Date
  2011-05-02
- Data Source
  KAKENHI-PROJECT-20510063
[Presentation] エストロゲン誘発性乳腺腫瘍に対するLPA受容体阻害剤Ki16425の予防効果2023
- Author(s)
  岡本誉士典、青木　明、神野透人
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] エストロゲン誘発性乳腺発がんの新規メカニズム解明を目指した血清代謝物の網羅的解析2023
- Author(s)
  岡本誉士典
- Organizer
  2023年度　内受容感覚研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] Chemo-preventive effect of Ki16425 a lysophosphatidic acid receptor inhibitor on estrogen-induced breast cancer in female ACI rats2023
- Author(s)
  Yoshinori Okamoto，Akira Aoki，Hideto Jinno
- Organizer
  The 10th International Congress of Asian Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] DNA損傷に着目した合成エストロゲンの発がんリスク低減に関する基盤研究2023
- Author(s)
  岡本誉士典
- Organizer
  がん予防学術大会2023金沢
- Invited
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] エストロゲン誘発性の乳がん形成に対するリゾホスファチジン酸受容体阻害剤の効果2023
- Author(s)
  岡本誉士典、青木　明、神野透人
- Organizer
  第69回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] ゲニステインによるヒト乳がん細胞株MDA-MB-231細胞の増殖抑制と細胞内リピドーム変化2021
- Author(s)
  山田浩之、岡本誉士典、森　葉子、青木　明、神野透人
- Organizer
  フォーラム2021：衛生薬学・環境トキシコロジー（千葉）
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] Rapid and simultaneous quantification of serum estrogens utilizing a pipette-tip solid-phase extraction method2021
- Author(s)
  Yoshinori Okamoto, Akira Aoki, Yoko Mori, Hideto Jinno
- Organizer
  The 21st Asian Conference on Clinical Pharmacy (Nagoya)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] 化学修飾によるエストロゲンの遺伝毒性低減：発がん研究の応用に向けた新しいアプローチ2021
- Author(s)
  岡本誉士典
- Organizer
  日本環境変異原ゲノム学会第50回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] 高分解能型質量分析計を用いたエストロゲンの迅速一斉分析法の確立2020
- Author(s)
  岡本誉士典，森　葉子，青木　明，神野透人
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] Pipette-tip固相抽出法を用いた簡便・安価な血清中エストロゲン抽出法の開発2020
- Author(s)
  藍澤恵莉，岡本誉士典，森　葉子，青木　明，神野透人
- Organizer
  フォーラム2020：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-20K12186
[Presentation] 白金4価錯体によるシスプラチン耐性ヒト卵巣がん細胞障害作用への活性酸素種生成の寄与2016
- Author(s)
  岡本誉士典、植田康次、小嶋仲夫、神野透人
- Organizer
  日本酸化ストレス学会東海支部　第4回学術集会
- Place of Presentation
  鈴鹿
- Year and Date
  2016-02-06
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry2016
- Author(s)
  Yoshinori Okamoto, Naoko Yoshida, Toru Suzuki, Nobuhiro Shimozawa, Maki Asami, Tomonari Matsuda, Nakao Kojima, Anthony C. F. Perry, and Tatsuyuki Takada
- Organizer
  International Symposium on "Epigenome Dynamics and Regulation in Germ Cells 2016"
- Place of Presentation
  京都
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25550036
[Presentation] cis-Diammine-tetrachloro-platinum(IV) は活性酸素種生成を介してシスプラチン耐性ヒト卵巣がん細胞に障害作用を引き起こす2015
- Author(s)
  戸邊隆夫、清水崇光、野中志保、植田康次、岡本誉士典、小嶋仲夫、神野透人
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Cisplatin耐性がん細胞に対するcis-Pt(IV)の細胞障害性と活性酸素種生成2015
- Author(s)
  戸邊隆夫、清水崇光、棚橋侑也、野中志保、岡本誉士典、植田康次、神野透人
- Organizer
  メタルバイオサイエンス研究会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Anti-cancer effect of platinum(IV) complex against cisplatin-resistant human ovarian cancer2015
- Author(s)
  Yoshinori Okamoto, Takao Tobe, Koji Ueda, Nakao Kojima
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  フィラデルフィア、アメリカ
- Year and Date
  2015-04-22
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] マウス胚性幹細胞の発がん性多環芳香族炭化水素に対する感受性の比較2015
- Author(s)
  長谷川祥子、戸邊隆夫、若原美沙紀、植田康次、岡本誉士典、高田達之、小嶋仲夫、神野透人
- Organizer
  第61回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25550036
[Presentation] Anti-cancer effect of platinum(IV) complex against cisplatin-resistant human ovarian cancer2015
- Author(s)
  Yoshinori Okamoto, Takao Tobe, Koji Ueda, Nakao Kojima
- Organizer
  American Association for Cancer Research Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Cytotoxicity of Pt(IV) complexes against cisplatin-resistant human ovarian cancer cells -Potential role of reactive oxygen species-2014
- Author(s)
  清水崇光、戸邊隆夫、清水香琳、本山美貴、岡本誉士典、植田康次、小嶋仲夫
- Organizer
  第24回金属の関与する生体関連反応シンポジウムSRM2014
- Place of Presentation
  京都
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Anti-cancer effects of Pt(IV) complex in cisplatin-resistant ovarian cancer cells2014
- Author(s)
  Takao Tobe, Karin Shimizu, Miki Motoyama, Koji Ueda, Yoshinori Okamoto, Nakao Kojima
- Organizer
  12th European Biological Inorganic Chemistry Conference
- Place of Presentation
  スイス、チューリッヒ
- Year and Date
  2014-08-27
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] 紫外線曝露によるマウス胚性幹細胞のp53非依存的細胞死2014
- Author(s)
  清水優希、戸邊隆夫、岡本誉士典、植田康次、高田達之、小嶋仲夫
- Organizer
  フォーラム2014：衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19
- Data Source
  KAKENHI-PROJECT-25550036
[Presentation] Molecular mechanism analysis of cytotoxicity induced by platinum(IV) complexes against cisplatin-resistant human ovarian cancer2014
- Author(s)
  戸邊隆夫、清水香琳、本山美貴、植田康次、岡本誉士典、小嶋仲夫
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Pt(IV)錯体の配位子依存的がん細胞障害性と細胞内分布挙動2013
- Author(s)
  清水香琳、戸邊隆夫、臼井健悟、徐　佳典、植田康次、岡本誉士典、小嶋仲夫
- Organizer
  フォーラム2013：衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] Ligand-dependent influx/efflux pattern of Pt(IV) complexes and their relevance to cytotoxicity in human ovarian cancer cells2013
- Author(s)
  戸邊隆夫、臼井健吾、徐　佳典、植田康次、岡本誉士典、小嶋仲夫
- Organizer
  第23回金属の関与する生体関連反応シンポジウムSRM2013
- Place of Presentation
  武蔵野
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] DNA付加体形成によるマウス胚性幹細胞の未分化状態および自己複製への影響2013
- Author(s)
  岡本誉士典
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 多能性幹細胞の神経系分化誘導と金属による神経毒性研究への応用2013
- Author(s)
  岡本誉士典
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 白金4価錯体による酸化的遺伝子損傷および配位子依存性2013
- Author(s)
  岡本誉士典、臼井健吾、徐　佳典、清水香琳、本山美貴、植田康次、小嶋仲夫
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460047
[Presentation] 植物由来プレニル化ゲニステインの構造変化によるエストロゲン受容体転写調節の正負変動2012
- Author(s)
  有田卓矢、岡本誉士典、岩田綾香、安井彩、山中彩歌、吉田将之、植田康次、井藤千裕、小嶋仲夫
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] 幹細胞に対する化学発がん物質のDNA損傷作用と未分化状態への影響2012
- Author(s)
  岡本誉士典、小嶋仲夫
- Organizer
  フォーラム2012：衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マウス胚性幹細胞における7,12-ジメチルベンズ(a)アントラセンのDNA損傷が引き起こす未分化状態の破綻2012
- Author(s)
  岡本誉士典
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Year and Date
  2012-07-18
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 多環芳香族炭化水素によるマウス胚性幹細胞へのDNA付加体形成と未分化状態への影響2012
- Author(s)
  岡本誉士典
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] エストロゲン様物質によるマウス胚性幹細胞の分化調節2012
- Author(s)
  岡本誉士典
- Organizer
  第31回生体と金属・化学物質に関する研究会(チョークトーク2012)
- Place of Presentation
  広島
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] Disruption of undifferentiated state accompanied by DNA damage in murine embryonic stem cells induced by7,12-dimethylbenz(a)anthracene2012
- Author(s)
  Yoshinori Okamoto
- Organizer
  6th International Congress of Asian Society of Toxicology
- Place of Presentation
  Sendai, Japan
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] プレニル化イソフラボン類によるエストロゲン様活性とその構造的特徴2012
- Author(s)
  岡本誉士典、岩田綾香、安井彩、山中彩歌、植田康次、井藤千裕、小嶋仲夫
- Organizer
  日本食品化学学会第18回総会・学術大会
- Place of Presentation
  函館
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] Disruption of undifferentiated state accompanied by DNA damage in murine embryonic stem cells induced by 7,12-dimethylbenz(a)anthracene2012
- Author(s)
  Tomoko Iyoda, Yoshinori Okamoto, Mariko Ushida, Tatsuyuki Takada, and Nakao Kojima
- Organizer
  6th International Congress of Asian Society of Toxicology
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] フラボノイド類がマウス胚性幹細胞分化に及ぼす影響2012
- Author(s)
  岡本誉士典
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マウス胚性幹細胞を用いた分化評価系の構築と植物フラボノイド類の効果2012
- Author(s)
  岡本誉士典
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 幹細胞に対する化学発がん物質のDNA損傷作用と未分化状態への影響.フォーラム20122012
- Author(s)
  岡本誉士典
- Organizer
  衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 化学発がん物質によるDNA損傷が引き起こす幹細胞の未分化状態のゆらぎ2012
- Author(s)
  岡本誉士典
- Organizer
  第58回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 植物由来ゲニステイン誘導体のプレニル基水酸化によるエストロゲン受容体転写調節の正負変動2012
- Author(s)
  有田卓矢、岡本誉士典、岩田綾香、安井彩、山中彩歌、吉田将之、植田康次、井藤千裕、小嶋仲夫
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] マウス胚性幹細胞において7,12-ジメチルベンズ(a)アントラセンが引き起こすDNA損傷-分化細胞との比較-2011
- Author(s)
  岡本誉士典
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] エストロゲン受容体転写調節作用を有する Garcinia 属植物由来化合物の構造的特徴2011
- Author(s)
  岡本誉士典、森　大貴、木村優里、榊原布尚、岩田綾香、井藤千裕、古川宏、小嶋仲夫
- Organizer
  第 56 回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] DMBA 曝露によるマウス胚性幹細胞のDNA 損傷および異物代謝酵素発現2011
- Author(s)
  牛田真理子，岡本誉士典，前田祐果，高田達之，小嶋仲夫
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 他マウス胚性幹細胞の3-メチルコラントレン処理による異物代謝酵素誘導2011
- Author(s)
  岡本誉士典
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マウス胚性幹細胞において7,12-ジメチルベンズ(a)アントラセンが引き起こすDNA損傷―分化細胞との比較―2011
- Author(s)
  牛田真理子，岡本誉士典，前田祐果，高田達之，小嶋仲夫
- Organizer
  フォーラム2011 衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] Induction of xenobiotic-metabolizing enzymes by 3-methylcholanthrene in murine embryonic stem cells2011
- Author(s)
  Yoshinori Okamoto, Yuka Maeda, Kumi Tomatsu, Tatsuyuki Takada, Nakao Kojima
- Organizer
  47th Congress of the European societies of Toxicology
- Place of Presentation
  フランス、パリ
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] Induction of xenobiotic-metabolizing enzymes by3-methylcholanthrene in murine embryonic stem cells2011
- Author(s)
  Yoshinori Okamoto
- Organizer
  47th Congress of the European societies of Toxicolog
- Place of Presentation
  Paris, France
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マウス胚性幹細胞を用いた神経細胞分化と化学物質による影響評価2011
- Author(s)
  岡本誉士典, 他1名
- Organizer
  名城大学学術フロンティア推進事業第3回若手研究者シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] セレン架橋チオール化合物の酸化的DNA損傷抑制作用と還元型チオール共存による作用変動2011
- Author(s)
  岡本誉士典, 他7名
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] DMBA曝露によるマウス胚性幹細胞のDNA損傷および異物代謝酵素発現2011
- Author(s)
  岡本誉士典
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] 植物由来化合物によるエストロゲン受容体転写調節における構造的特徴2011
- Author(s)
  岡本誉士典, 他5名
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 生体内還元物質共存下におけるPt(IV)化合物の酸化的DNA損傷と配意子の影響2011
- Author(s)
  岡本誉士典, 他5名
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] マウス胚性幹細胞の化学物質による異物代謝酵素発現誘導とDNA損傷2011
- Author(s)
  岡本誉士典
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マンガンのSOD様作用・自動酸化促進による鉄-/銅-カテコール誘導酸化的DNA損傷の増強2011
- Author(s)
  岡本誉士典, 他5名
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  静岡
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] マウス胚性幹細胞を用いた神経細胞分化と化学物質による影響評価2011
- Author(s)
  岡本誉士典, 他1名
- Organizer
  名城大学学術フロンティア推進事業第3回若手研究者シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] マウス胚性幹細胞の3-メチルコラントレン処理による異物代謝酵素誘導2011
- Author(s)
  前田祐果、岡本誉士典、戸松久美、高田達之、小嶋仲夫
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PUBLICLY-21028021
[Presentation] マンガンのSOD様作用・自動酸化促進による鉄-/銅-カテコール誘導酸化的DNA損傷の増強2011
- Author(s)
  岡本誉士典, 他5名
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  東京
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 遺伝子中のメチル化塩基の迅速・高感度測定法とその応用2011
- Author(s)
  岡本誉士典
- Organizer
  第4回名古屋大学「医学・バイオ系知財フェア」
- Place of Presentation
  名古屋
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] マウス胚性幹細胞の3-メチルコラントレン処理による異物代謝酵素誘導2011
- Author(s)
  前田祐果，岡本誉士典，戸松久美，高田達之，小嶋仲夫
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790162
[Presentation] Fe(III)-/Cu(II)-カテコール化合物介在性酸化的DNA損傷に対するMn(II)のSOD様作用・自動酸化促進による増強効果2011
- Author(s)
  岡本誉士典,, 他5名
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] エストロゲン受容体転写調節作用を有するGarcinia属植物由来化合物の構造的特徴2011
- Author(s)
  岡本誉士典、森大貴、木村優里、榊原布尚、岩田綾香、井藤千裕、古川宏、小嶋仲夫
- Organizer
  第56回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] 新しい抗エストロゲン化合物:遺伝毒性および女性ホルモン作用の無い乳がん治療薬の開発2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] DNA oxidation induced by platinum(IV) compound in the presence of endogenous reductants.2010
- Author(s)
  岡本誉士典, 他5名
- Organizer
  AACR 101st Annual Meeting
- Place of Presentation
  米国ワシントンD.C.
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 生体内チオール化合物のセレン架橋生成物が示す遺伝子損傷抑制作用2010
- Author(s)
  岡本誉士典, 他7名
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 植物由来化合物によるエストロゲン受容体転写調節と成分総和による作用緩和2010
- Author(s)
  岡本誉士典, 他7名
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] カテコールアミン酸化中間体および生体内金属による酸化的DNA損傷と神経変性における役割2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  第63回日本酸化ストレス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] カテコールアミンによる遺伝子損傷におけるロイコアミノクロム生成の重要性2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Metal-mediated oxidative DNA damage induced by endogenous catecholamines and its suppressive effect on gene expression2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  第20回金属の関与する生体関連反応シンポジウムSRM2010
- Place of Presentation
  徳島
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 生体内チオール化合物のセレン架橋生成物が示す遺伝子損傷抑制作用2010
- Author(s)
  岡本誉士典, 他7名
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] カテコールアミンによる遺伝子損傷におけるロイコアミノクロム生成の重要性2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 生体内還元物質によって変動するPt(IV)化合物の酸化的DNA損傷および架橋形成作用2010
- Author(s)
  岡本誉士典, 他5名
- Organizer
  第37回日本トキシコロジー学会学術年会
- Place of Presentation
  宜野湾
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Novel antiestrogens, SS1020 and SS5020, for breast cancer therapy and prevention2010
- Author(s)
  Yoshinori Okamoto, 他5名
- Organizer
  AACR 101st Annual Meeting 2010
- Place of Presentation
  ワシントンDC、アメリカ
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Metal-mediated oxidative DNA damage induced by endogenous catecholamines and its suppressive effect on gene expression2010
- Author(s)
  岡本誉士典, 他4名
- Organizer
  第20回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] ポリセレノジペニシラミンの生成機構とCu(II)-カテコール依存的DNA損傷抑制効果2010
- Author(s)
  岡本誉士典, 他7名
- Organizer
  第56回日本薬学会東海支部総会・大会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 食品由来成分によるエストロゲン受容体転写発現への影響2010
- Author(s)
  岡本誉士典, 他6名
- Organizer
  日本食品化学学会第16回総会・学術大会
- Place of Presentation
  大阪
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Production of polyselenodipenicillamines, unique selenium compounds.2010
- Author(s)
  岡本誉士典, 他5名
- Organizer
  9th International Symposium on Selenium in Biology and Medicine
- Place of Presentation
  京都
- Year and Date
  2010-06-01
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] エストロゲン受容体転写に対するブラジル産プロポリス各種成分の多彩な正負作用と成分総和による作用緩和2010
- Author(s)
  岡本誉士典, 他6名
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] DNA oxidation induced by platinum(IV) compound in the presence of endogenous reductants2010
- Author(s)
  Yoshinori Okamoto, 他5名
- Organizer
  AACR 101st Annual Meeting 2010
- Place of Presentation
  ワシントンDC、アメリカ
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Novel antiestrogens, SS1020 and SS5020, for breast cancer therapy and prevention.2010
- Author(s)
  岡本誉士典, 他5名
- Organizer
  AACR 101st Annual Meeting
- Place of Presentation
  米国ワシントンD.C.
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Production of polyselenodipenicillamines, unique selenium compounds2010
- Author(s)
  Yoshinori Okamoto, 他5名
- Organizer
  9th International Symposium on Selenium in Biology and Medicine
- Place of Presentation
  京都
- Year and Date
  2010-06-01
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] エストロゲン受容体転写に対するブラジル産プロポリス各種成分の多彩な正負作用と成分総和による作用緩和2010
- Author(s)
  岡本誉士典, 他5名
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] 植物由来化合物によるエストロゲン受容体転写調節と成分総和による作用緩和2010
- Author(s)
  岡本誉士典, 他7名
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Place of Presentation
  静岡
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21890279
[Presentation] Non-human primate ES細胞の分化過程における生殖細胞マーカー遺伝子の発現変化2009
- Author(s)
  太田康夫、橋本圭史、青木智弘、岡本誉士典、鳥居隆三、野瀬俊明、高田達之
- Organizer
  文部科学省・科学研究費補助金・特定領域研究「生殖系列の世代サイクルとエピゲノムネットワーク」
- Place of Presentation
  第2回公開シンポジウム、コクヨホール(東京都)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20510063
[Presentation] Non-human primate ES 細胞の生殖細胞への分化2009
- Author(s)
  太田康夫、橋本圭史、青木智弘、岡本誉士典、鳥居隆三、野瀬俊明、高田達之
- Organizer
  文部科学省・科学研究費補助金・特定領域研究「生殖系列の世代サイクルとエピゲノムネットワーク」生殖サイクル若手勉強会2009
- Place of Presentation
  御殿場高原ホテル(静岡県)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20510063
[Presentation] Derivation of rat cell line which contribute to visceral yolk sac2009
- Author(s)
  Takada T., Masuda C., Okamoto Y., Tooyama I., Kato M., Hirabayashi M.
- Organizer
  7th Annual Meeting of the International Society for Stem Cell Research
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-20510063
[Presentation] プレニル化イソフラボン類によるエストロゲン様活性とその構造的特徴
- Author(s)
  岡本誉士典、岩田綾香、安井　彩、山中彩歌、植田康次、井藤千裕、小嶋仲夫
- Organizer
  日本食品化学学会第18回総会・学術大会
- Place of Presentation
  函館
- Data Source
  KAKENHI-PROJECT-23590026
[Presentation] 植物由来ゲニステイン誘導体のプレニル基水酸化によるエストロゲン受容体転写調節の正負変動
- Author(s)
  有田卓矢、岡本誉士典、岩田綾香、安井　彩、山中彩歌、吉田将之、植田康次、井藤千裕、小嶋仲夫
- Organizer
  日本病院薬剤師東海ブロック・日本薬学会東海支部合同学術大会2012
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23590026

1. KOJIMA Nakao (80333178)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. TAKADA Tatsuyuki (90206756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. NOCE Toshiaki (70183902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. ITO CHIHIRO (60193497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. UEDA Koji (30351092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. NAKAMURA Tomohumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 菅澤薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAMOTO Yoshinori 岡本 誉士典

Okamoto Yoshinori 岡本 誉士典

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Identification of novel carcinogenic mechanisms for mammary gland induced by lipid-mediatorsPrincipal Investigator

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Determination of intra-cellular dynamics of platinum(IV) complexes using imaging technique

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A picture of whole DNA modification induced by carcinogens: Whole-genome analysis for sequence specificity and vulnerabilityPrincipal Investigator

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Research on active compounds from natural resources affecting the differentiation of ES and iPS cells

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Determination of carcinogenic me chanisms in stem cells using ES/iPS cellsPrincipal Investigator

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Non-human Primate ES細胞の生殖細胞への分化

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Simulation and analysis of stem cell-carcinogenesis induced by chemical carcinogens using murine embryonic stem cellPrincipal Investigator

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Validation system of chemicals using BAC vector transfected ES cells

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[Journal Article] Less Carcinogenic Chlorinated Estrogens Applicable to Hormone Replacement Therapy2021

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[Journal Article] DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry2016

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[Journal Article] Thiol-mediated multiple mechanisms centered on selenodiglutathione determine selenium cytotoxicity against MCF-7 cancer cells.2015

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[Journal Article] Oral administration of Brazilian propolis exerts estrogenic effect in ovariectomized rats2015

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[Journal Article] Oral administration of Brazilian propolis exerts estrogenic effect in ovariectomized rats.2015

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OKAMOTO Yoshinori 岡本誉士典

Okamoto Yoshinori 岡本誉士典