Nagai Takashi 永井崇

… Alternative Names

NAGAI Takashi 永井崇

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Researcher Number	50514353
Affiliation (based on the past Project Information) *help	2020 – 2022: 信州大学, 医学部附属病院, 特任助教 2021: 信州大学, 学術研究員医学系(医学部), 特任研究員 2018: 信州大学, 学術研究院医学系(医学部附属病院), 助教 2017: 信州大学, 医学部, 助教 2016: 信州大学, 学術研究院医学系(医学部附属病院), 助教 2012 – 2013: 信州大学, 医学部, 助教 2008 – 2009: 信州大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Digestive surgery / Basic Section 56030:Urology-related / Urology / General physiology
Keywords	Principal Investigator ニコチン / ニコチン受容体 / アクアポリン / バソプレシン受容体 / TRPV4 / nocturia / menthol / skin stimulation / renal function / skin … More / urinary frequency / polyuria / smoking cessation / TRPM8 / LUTS / hypoxia / cold stress / nicotine / 排尿機能学 / 病態生理学 / 低酸素マーカー（HIF1α） / 高血圧 / タダラフィル / 微小組織循環 / 低酸素マーカー(HIF1α) / Uroplakin Ⅲ / Aquaporin 3 / 微小循環障害 / 生活習慣病 / ＵＰⅢ / ＡＱＰ3 / ＨＩＦ１α / 尿路上皮 / 下部尿路症状 / HTF1a / AQP3 … More Except Principal Investigator センチネルリンパ節 / 癌転移 / 微小環境 / ATP / 生体顕微鏡観察 / 立体構造体 / 間葉系細胞 / 下部尿路 / 脂肪幹細胞 / 尿道 / 膀胱 / 骨髄幹細胞 / 再生医療 / 薬剤反応性 / 生理学 / ケモカイン / 間質性膀胱炎 / 病態生理 / ecNOS / ICAM-1 / 超音波診断装置 / リンパ管内皮細胞 / リンパ節 / リンパ系 / 循環生理学 / プロスタグランジン / 一酸化窒素 / ペグ付きリポソーム / 分子イメージング / CCL2 / 癌微小環境 / 微小癌転移 / 癌抗原 / 分子プロファイリング Less

3D structure Tissue Engineering of lower urinary tract using mesenchemal stem cells.
- Principal Investigator
  
  Ishizuka Osamu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Shinshu University
Analysis of the histological and functional effects due to long-term nicotine intaking on the kidney and bladder, and analysis of the effect of smoking cessation.Principal Investigator
- Principal Investigator
  
  Nagai Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Shinshu University
The relation between expression of aquaporin within urothelium and change of morphology and function of urothelium in various diseases.Principal Investigator
- Principal Investigator
  
  Nagai Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shinshu University
The development of new agents for the interstital cystitis / bladder pain syndrome base on gene profile
- Principal Investigator
  
  Ogawa Teruyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shinshu University
Development of imaging changes in microenvironment with in the sentinel lymph node combined with micrometastasis of carcinoma cells
- Principal Investigator
  
  OHHASHI Toshio
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Shinshu University
Molecular and physiological approach for addressing the mechanisms of micrometastasis of carcinoma cells within the sentinel lymph node
- Principal Investigator
  
  OHHASHI Toshio
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Shinshu University
Basic and clinical research for evaluating micro-environmental changes in sentinel lymph node produced by micro-metastasis of carcinoma cell.
- Principal Investigator
  
  OHHASHI Toshio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Shinshu University

All 2022 2019 2018 2017 2016 2013 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Combined treatment with a β3 -adrenergic receptor agonist and a muscarinic receptor antagonist inhibits detrusor overactivity induced by cold stress in spontaneously hypertensive rats2017
- Author(s)
  Imamura T, Ogawa T, Minagawa T, Nagai T, Suzuki T, Saito T, Yokoyama H, Nakazawa M, Ishizuka O
- Journal Title
  
  Neurourol Urodyn
  
  Volume: 36 Issue: 4 Pages: 1026-1033
- DOI
  10.1002/nau.23061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20081, KAKENHI-PROJECT-16K11045, KAKENHI-PROJECT-16K20129, KAKENHI-PROJECT-15K10622, KAKENHI-PROJECT-16K11043
[Journal Article] Lymphatic muscle cells in mesenteric lymphatic vessels of various ages2013
- Author(s)
  Bridenbaugh EA, Nizamutdinova IT, Jupiter D, Nagai T, Thangaswamy S, Chatterjee V, Gashev AA
- Journal Title
  
  Lymphat. Res. Biol
  
  Volume: 11 Pages: 35-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] Lymphatic muscle cells in mesenteric lymphatic vessels of various ages2013
- Author(s)
  Bridenbaugh EA, Nizamutdinova IT, Jupiter D, Nagai T, Thangaswamy S, Chatterjee V, Gashev AA
- Journal Title
  
  Lymphat. Res. Biol.
  
  Volume: 11 Pages: 35-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659098
[Journal Article] Real-time imaging of the lymphatic channels and sentinel lymph nodes of the stomach using contrast-enhanced ultrasonography with Sonazoid in a porcine model2011
- Author(s)
  Kawai Y, Ajima K, Nagai T, Kaidoh M, Ohhashi T
- Journal Title
  
  Cancer Sci.
  
  Volume: 102(11) Pages: 2073-2081
- NAID
  10030245346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] Mesenteric lymph flow in adult and aged rats2011
- Author(s)
  Aki TJ, Nagai T, Cote GL, Gashev AA
- Journal Title
  
  Am. J. Physiol. Heart. Circ. Physiol
  
  Volume: 301(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] Rear-time imaging of the lymphatic channels and sentinel lymph nodes of the stomach using contrast-enhanced ultrasonography with Sonazoid in a porcine model2011
- Author(s)
  Kawai Y, Ajima K, Nagai T, Kaidoh M, Ohhashi T
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 11 Pages: 2073-2081
- DOI
  10.1111/j.1349-7006.2011.02048.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] Aging-associated alterations in contractility of rat mesenteric lymphatic vessels2011
- Author(s)
  Nagai T, Bridenbaugh EA, Gashev AA
- Journal Title
  
  Microcirculation
  
  Volume: 18(6) Pages: 463-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] Indocyanine Green and lymphatic imaging : current problems2010
- Author(s)
  Gashev AA, Nagai T, Bridenbauch EA
- Journal Title
  
  Lymphat. Res. Biol
  
  Volume: 8(2) Pages: 127-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249052
[Journal Article] In situ lymph dynamic characterization through lymph nodes in rabbit hind leg : special reference to nodal inflammation.2008
- Author(s)
  Nagai T, Ikomi F, Suzuki S, Obhashi T
- Journal Title
  
  J. Physiol. Sci. 58
  
  Pages: 123-132
- NAID
  10022597949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209044
[Presentation] ニコチン長期投与ラットの膀胱機能に対する冷気暴露およびメンソール刺激の影響2022
- Author(s)
  永井崇, 今村哲也, 皆川倫範, 小川輝之, 石塚修
- Organizer
  第29回日本排尿機能学会
- Data Source
  KAKENHI-PROJECT-20K09576
[Presentation] シクロフォスファミドと放射線照射によって誘発してラット膀胱炎の特異的遺伝子発現との類似性の検討2019
- Author(s)
  今村哲也、小川輝之、鈴木都史郎、上野学、鈴木中、原寛敦、井上貴裕、永井崇、皆川倫範、石塚修
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11045
[Presentation] ニコチンは膀胱における尿路上皮の低酸素化とバリア機能の変化をもたらし頻尿をきたす2018
- Author(s)
  永井崇、今村哲也、上野学、鈴木都史郎、齊藤徹一、皆川倫範、道面尚久、小川典之、竹田裕、小川輝之、石塚修
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] Effect of tadalafil on improving hypoxic environment of urothelium and on restoring bladder storage function in the nicotine-treated rat2018
- Author(s)
  Takashi Nagai, Tetsuya Imamura, Manabu Ueno, Toshiro Suzuki, Takahisa Domen, Tomonori Minagawa, Teruyuki Ogawa, Osamu Nishizawa, and Osamu Ishizuka
- Organizer
  The 13th Pan-Pacific Continence Society meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] ニコチン投与がもたらす膀胱血流低下は尿路上皮で、より低酸素化をきたし、機能的構造的影響を受ける2018
- Author(s)
  永井崇、今村哲也、上野学、鈴木都史郎、道面尚久、皆川倫範、小川輝之、石塚修
- Organizer
  第25回日本排尿機能学会総会
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] The hypoxic environment decreases both aquaporin3 and uroplakinⅢ expressions and bladder storage functions in spontaneous hypertensive rats.2017
- Author(s)
  Nagai T
- Organizer
  ICS2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] ニコチンは膀胱における尿路上皮の低酸素化とバリア機能の変化をもたらし頻尿をきたす2017
- Author(s)
  永井崇
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] Hypertension brings about the hypoxic change of the bladder urothelium and causes the histological change of bladder urothelium and suburothelial tissue.2017
- Author(s)
  永井　崇
- Organizer
  第105回日本泌尿器科学会総会
- Place of Presentation
  城山観光ホテル（鹿児島市）
- Year and Date
  2017-04-21
- Data Source
  KAKENHI-PROJECT-16K11044
[Presentation] 尿流動態検査の結果からみた前立腺肥大症患者の至適手術時期の検討2016
- Author(s)
  斎藤徹一、石川雅邦、永井　崇、皆川倫範、小川輝之、市野みどり、石塚　修
- Organizer
  第23回日本排尿機能学会
- Place of Presentation
  東京・東京国際フォーラム
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K11045
[Presentation] 女性における過活動膀胱治療薬の服薬継続率について2016
- Author(s)
  小川輝之、皆川倫範、加賀美慧帆、松高　淳、小川典之、大門裕典、斎藤徹一、鈴木都史郎、道面尚久、石川雅邦、永井　崇、平形志朗、今村哲也、石塚　修
- Organizer
  第81回日本泌尿器学会東部総会
- Place of Presentation
  青森・リンクステーションホール青森
- Year and Date
  2016-10-09
- Data Source
  KAKENHI-PROJECT-16K11045
[Presentation] PDE阻害薬連続投与によるラット蓄尿機能変化と冷えストレスによる排尿筋過活動の抑制効果の検討2016
- Author(s)
  永井　崇、今村哲也、小川輝之、皆川倫範、鈴木都史郎、斎藤徹一、石塚　修
- Organizer
  第23回日本排尿機能学会
- Place of Presentation
  東京・東京国際フォーラム
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K11045
[Presentation] Detection of sentinel lymph node using contrast-enhanced ultrasonography with sonazoid in swine stomach in vivo2010
- Author(s)
  Kawai Y, Ajima K, Nagai T, Ohhashi T
- Organizer
  The 7th International Sentinel Node Society Meeting
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-22249052
[Presentation] 超音波造影剤を用いたブタ胃センチネルリンパ節の新しい同定法の確立2009
- Author(s)
  河合佳子、安嶋久美子、永井崇、鈴木滋、大橋俊夫
- Organizer
  第33回日本リンパ学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-19209044
[Presentation] Ultrasonographic detection of sentinel lymph nodes in vivo.2008
- Author(s)
  F. Ikomi, T. Nagai, S. Suzuki, T. Ohhashi
- Organizer
  第85回日本生理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19209044
[Presentation] センチネルリンパ節の生理学的基礎2007
- Author(s)
  伊古美文隆、永井崇、鈴木滋、水野理介、河合佳子、保坂佳代子、大橋俊夫
- Organizer
  第48回日本脈管学会総会シンポジウム
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19209044
[Presentation] ウサギ膝窩リンパ節内におけるスターリング力に依存した物質移動の評価2007
- Author(s)
  伊古美文隆、永井崇、鈴木滋、大橋俊夫
- Organizer
  第31回日本リンパ学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19209044
[Presentation] ウサギ膝窩リンパ節in vivo灌流標本を用いたスターリング力に依存した物質移動の解析2007
- Author(s)
  永井崇、伊古美文隆、鈴木滋、大橋俊夫
- Organizer
  第48回日本脈管学会総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19209044

1. Ishizuka Osamu (20184541)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. 今村哲也 (00467143)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. OHHASHI Toshio (80020832)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. KAWAI Yoshiko (10362112)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. AJIMA Kumiko (70584051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. Ogawa Teruyuki (90467142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. IKOMI Fumitaka (50262704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. MIZUNO Risuke (30273080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. HOSAKA Kayoko (30362122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 平形志朗 (90749475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 上野学 (00816340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 皆川倫範 (60638873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 道面尚久 (90750878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 横山仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Takashi 永井 崇

NAGAI Takashi 永井 崇

Research Projects

Research Products

Co-Researchers

3D structure Tissue Engineering of lower urinary tract using mesenchemal stem cells.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the histological and functional effects due to long-term nicotine intaking on the kidney and bladder, and analysis of the effect of smoking cessation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The relation between expression of aquaporin within urothelium and change of morphology and function of urothelium in various diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of new agents for the interstital cystitis / bladder pain syndrome base on gene profile

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of imaging changes in microenvironment with in the sentinel lymph node combined with micrometastasis of carcinoma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular and physiological approach for addressing the mechanisms of micrometastasis of carcinoma cells within the sentinel lymph node

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic and clinical research for evaluating micro-environmental changes in sentinel lymph node produced by micro-metastasis of carcinoma cell.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Combined treatment with a β3 -adrenergic receptor agonist and a muscarinic receptor antagonist inhibits detrusor overactivity induced by cold stress in spontaneously hypertensive rats2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymphatic muscle cells in mesenteric lymphatic vessels of various ages2013

Author(s)

Journal Title

Data Source

[Journal Article] Lymphatic muscle cells in mesenteric lymphatic vessels of various ages2013

Author(s)

Journal Title

Data Source

[Journal Article] Real-time imaging of the lymphatic channels and sentinel lymph nodes of the stomach using contrast-enhanced ultrasonography with Sonazoid in a porcine model2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Mesenteric lymph flow in adult and aged rats2011

Author(s)

Journal Title

Data Source

[Journal Article] Rear-time imaging of the lymphatic channels and sentinel lymph nodes of the stomach using contrast-enhanced ultrasonography with Sonazoid in a porcine model2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aging-associated alterations in contractility of rat mesenteric lymphatic vessels2011

Author(s)

Journal Title

Data Source

[Journal Article] Indocyanine Green and lymphatic imaging : current problems2010

Author(s)

Nagai Takashi 永井崇

NAGAI Takashi 永井崇