Shibata Kensuke 柴田健輔

… Alternative Names

SHIBATA Kensuke 柴田健輔

SHBATA Kensuke 柴田健輔

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Researcher Number	50529972
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 山口大学, 大学院医学系研究科, 講師 2016 – 2017: 九州大学, 医学研究院, 助教 2010 – 2012: 九州大学, 生体防御医学研究所, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 56060:Ophthalmology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 49070:Immunology-related / Experimental pathology / Immunology Except Principal Investigator Basic Section 56060:Ophthalmology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 49010:Pathological biochemistry-related / Basic Section 55020:Digestive surgery-related / Basic Section 53010:Gastroenterology-related / Bacteriology (including Mycology)
Keywords	Principal Investigator T細胞 / 自己免疫性疾患 / 代謝産物 / 免疫療法 / 腸内細菌由来代謝産物 / 共生微生物 / 医薬分子機能学 / 細胞免疫療法 / 腫瘍免疫 / ガン免疫療法 … More / ガン / 疾患モデル動物 / 自己抗体 / 自己免疫疾患 / サイトカイン / IL-17産生gd T細胞 / 粘膜免疫 … More Except Principal Investigator YAP / メカノホメオスターシス / ぶどう膜炎 / オルガノイド / がん免疫 / 炎症性腸疾患 / 感染免疫 / 出力系時計遺伝子 / マクロファージ / E4BP4 / 免疫チェックポイント / 腸内細菌叢 / 人工腸管 / 力学恒常性 / がんオルガノイド / イメージング・マスサイトメトリー / メカノホメオスターシス / YAPレポーターマウス / magnetic tweezers法 / CODEX法 / 磁気ピンセット法 / PhenoCycler / がん免疫微小環境 / YAPの活性化 / YAP活性化 / がん発症・進展 / 自然リンパ球 / MAIT細胞 / 腸炎 / サイトカイン / 感染 / IL8 / IL-8 / サルモネラ / MHC / MST1/2 / Hippo経路 / ribD / Francisella tularensis / MAIT cell / Hippo / 力学特性 / 免疫チェックポイント療法 / リンパ節 / DAMPs / 神経炎症 / 網膜色素変性 / 負の選択 / γインターフェロン / キラー活性 / リステリア感染 / HY特異性CD8T細胞 / IL-15 / IL-2 / 腸内細菌 / IL-17 / CD301 / 自然免疫T細胞 / IL-12/IL-15 / 感染防禦 / IFN-gamma / Listeria monocytogenes / CD30L / 自然免疫CD4+T細胞 Less

空間遺伝子発現解析による自己免疫性ぶどう膜炎後に誘導される視覚保護機構の解明Principal Investigator
- Principal Investigator
  
  柴田健輔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamaguchi University
共生微生物由来代謝産物を感知するMAIT細胞による功と罪Principal Investigator
- Principal Investigator
  
  柴田健輔
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yamaguchi University
自己分子としての共生微生物由来代謝産物の免疫学的意義の解明Principal Investigator
- Principal Investigator
  
  柴田健輔
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yamaguchi University
Development of a treatment strategy for autoimmune uveitis using metabolites derived from intestinal bacteriaPrincipal Investigator
- Principal Investigator
  
  柴田健輔
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Yamaguchi University
出力系時計遺伝子に着目した炎症性腸疾患の病態解明と治療法の展開
- Principal Investigator
  
  田口昭彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yamaguchi University
MAIT細胞活性化による慢性炎症性眼疾患治療の確立
- Principal Investigator
  
  長谷川英一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
A mini-organ culture system with cancer immune microenvironment recapitulating in vivo
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
がん発症・進展過程におけるYAPの活性化の機械的制御機構の解明
- Principal Investigator
  
  田尾嘉誉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of innovative cancer immunotherapy targeting metabolites applicable to all patientsPrincipal Investigator
- Principal Investigator
  
  Shibata Kensuke
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Yamaguchi University
Regulation of Inflammation by DAMPs and MAIT cells associated with prolonged uveitis.
- Principal Investigator
  
  Hasegawa Eiichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
Identification of DAMPs Recognition Mechanisms that Regulate Neuroinflammation in Retinitis Pigmentosa
- Principal Investigator
  
  Murakami Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyushu University
Creation of lyph node organoids enabling mechanical control of immunity
- Principal Investigator
  
  Seiki Makoto
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Yamaguchi University
3D intestinal development and carcinogenesis by Hippo-YAP pathway
- Principal Investigator
  
  MUTSUNORI SHIRAI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
Elucidation of molecular mehcanisms of autoimmune pancreatitisPrincipal Investigator
- Principal Investigator
  
  SHIBATA Kensuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamaguchi University
  Kyushu University
Immunoregulation and therapeutic application of IL-17-producing gamm delta T cellsPrincipal Investigator
- Principal Investigator
  
  SHIBATA Kensuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kyushu University
The roles of innate T cells in bacterial infection
- Principal Investigator
  
  YOSHIKAI Yasunobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kyushu University

[Book] ビタミンB2合成中間体由来代謝産物を認識する粘膜関連T細胞の作用2023
- Author(s)
  柴田健輔 , 山名智志 , 園田康平
- Total Pages
  133
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PUBLICLY-23H04784
[Book] 臨床免疫・アレルギー科2023
- Author(s)
  柴田健輔、山名智志、園田康平
- Total Pages
  133
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23K18330
[Book] IL-17産生gd T細胞の分化と活性化2012
- Author(s)
  柴田健輔
- Total Pages
  5
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PROJECT-22790468
[Book] 臨床免疫・アレルギー科2012
- Author(s)
  柴田健輔
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] Single-cell analysis for identification of T-cell clonotypes associated with IgG4 production of autoimmune pancreatitis2024
- Author(s)
  Shibata Kensuke、Fujimori Nao、Oono Takamasa、Motooka Daisuke、Okuzaki Daisuke、Sonoda Koh-Hei、Ogawa Yoshihiro、Yamasaki Sho
- Journal Title
  
  Gastroenterology Report
  
  Volume: 11
- DOI
  10.1093/gastro/goad071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18330, KAKENHI-PLANNED-22H05183, KAKENHI-PUBLICLY-23H04784, KAKENHI-PROJECT-23H00403, KAKENHI-PROJECT-23K27671
[Journal Article] Sulfated bile acid is a host-derived ligand for MAIT cells.2024
- Author(s)
  Ito E, Inuki S, Izumi Y, Takahashi M, Dambayashi Y, Ciacchi L, Awad W, Takeyama A, Shibata K, Mori S, Mak JYW, Fairlie DP, Bamba T, Ishikawa E, Nagae M, Rossjohn J, Yamasaki S*.
- Journal Title
  
  Science Immunology
  
  Volume: 9(91) Issue: 91 Pages: 100492-100492
- DOI
  10.1126/sciimmunol.ade6924
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18924, KAKENHI-PROJECT-22KJ2094, KAKENHI-ORGANIZER-22H05182, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-22H05185, KAKENHI-PUBLICLY-23H04784, KAKENHI-PROJECT-23H00403
[Journal Article] Functions of mucosal associated invariant T cells in eye diseases2024
- Author(s)
  Fukui Chihiro、Yamana Satoshi、Xue Yanqi、Shirane Mariko、Tsutsui Hiroki、Asahara Kenichiro、Yoshitomi Keiko、Ito Takako、Lestari Tantri、Hasegawa Eiichi、Yawata Nobuyo、Takeda Atsunobu、Sonoda Koh-Hei、Shibata Kensuke
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15
- DOI
  10.3389/fimmu.2024.1341180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18330, KAKENHI-PROJECT-21K09723, KAKENHI-PUBLICLY-23H04784
[Journal Article] Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b2022
- Author(s)
  Shibata Kensuke、Motozono Chihiro、Nagae Masamichi、Shimizu Takashi、Ishikawa Eri、Motooka Daisuke、Okuzaki Daisuke、Izumi Yoshihiro、Takahashi Masatomo、Fujimori Nao、Wing James B.、Hayano Takahide、Asai Yoshiyuki、Bamba Takeshi、Ogawa Yoshihiro、Furutani-Seiki Makoto、Shirai Mutsunori、Yamasaki Sho
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6948-6948
- DOI
  10.1038/s41467-022-34802-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07539, KAKENHI-PROJECT-22K18924, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-23K23151, KAKENHI-PROJECT-23K24139
[Journal Article] The intracellular pathogen <i>Francisella tularensis</i> escapes from adaptive immunity by metabolic adaptation2022
- Author(s)
  Shibata Kensuke、Shimizu Takashi、Nakahara Mashio、Ito Emi、Legoux Francois、Fujii Shotaro、Yamada Yuka、Furutani-Seiki Makoto、Lantz Olivier、Yamasaki Sho、Watarai Masahisa、Shirai Mutsunori
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 10 Pages: e202201441-e202201441
- DOI
  10.26508/lsa.202201441
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07539, KAKENHI-PROJECT-22K07054, KAKENHI-PLANNED-22H05183, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-23K21272
[Journal Article] An intracellular pathogen Francisella tularensis escapes from host immunity by metabolic reprogramming.2022
- Author(s)
  Kensuke Shibata, Takashi Shimizu, Mashio Nakahara, Francois Legoux,Sho Yamasaki, Makoto Furutani-Seiki, Olivier Lantz, Masahisa Watarai, Mutsunori Shirai
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08424
[Journal Article] Mucosal-associated invariant T cells have therapeutic potential against ocular autoimmunity2021
- Author(s)
  Yamana Satoshi、Shibata Kensuke、Hasegawa Eiichi、Arima Mitsuru、Shimokawa Shotaro、Yawata Nobuyo、Takeda Atsunobu、Yamasaki Sho、Sonoda Koh-Hei
- Journal Title
  
  Mucosal Immunology
  
  Volume: 15 Issue: 2 Pages: 351-361
- DOI
  10.1038/s41385-021-00469-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K07539, KAKENHI-PROJECT-20K09792, KAKENHI-PROJECT-21K09723
[Journal Article] Agonistic or antagonistic mucosal-associated invariant T (MAIT) cell activity is determined by the 6-alkylamino substituent on uracil MR1 ligands2020
- Author(s)
  Braganza Chriselle D.、Motozono Chihiro、Sonoda Koh-Hei、Yamasaki Sho、Shibata Kensuke、Timmer Mattie S. M.、Stocker Bridget L.
- Journal Title
  
  Chemical Communications
  
  Volume: in press Issue: 39 Pages: 529-5294
- DOI
  10.1039/d0cc00247j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04087, KAKENHI-PROJECT-19K07623, KAKENHI-PROJECT-20K07539, KAKENHI-PROJECT-20H00505
[Journal Article] Agonistic or antagonistic mucosal-associated invariant T (MAIT) cell activity is determined by the 6-alkylamino substituent on uracil MR1 ligands.2020
- Author(s)
  Braganza CD1, Motozono C2, Sonoda KH3, Yamasaki S4, Shibata K5, Timmer MSM1, Stocker BL
- Journal Title
  
  Chem Commun (Camb).
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-19K08424
[Journal Article] In Staphylococcus aureus, the Particulate State of the Cell Envelope Is Required for the Efficient Induction of Host Defense Responses.2019
- Author(s)
  Kim B, Jiang T, Bae JH, Yun HS, Jang SH, Kim JH, Kim JD, Hur JH, Shibata K, Kurokawa K, Jung Y, Peschel A, Bae T, Lee BL.
- Journal Title
  
  Infect Immun. 87(12). pii: e00674-19, 2019.
  
  Volume: 87 Issue: 12
- DOI
  10.1128/iai.00674-19
- Data Source
  KAKENHI-PROJECT-19K08424
[Journal Article] The effect of MR1 ligand glycol-analogues on mucosal-associated invariant T (MAIT) cell activation.2019
- Author(s)
  Braganza, CD., Shibata, K., Fujiwara, A., Motozono, C., Sonoda, KH., Yamasaki, S., Stocker, BL., Timmer, MSM.
- Journal Title
  
  Org Biomol Chem.
  
  Volume: 17 Issue: 40 Pages: 8992-9000
- DOI
  10.1039/c9ob01436e
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07623, KAKENHI-PROJECT-19K08424, KAKENHI-PROJECT-17H04087, KAKENHI-PROJECT-16H06276
[Journal Article] In vivo blockade of T cell development reveals alternative pathways for generation of intraepithelial lymphocytes in mice2017
- Author(s)
  Mondoon Surenchimeg、Shibata Kensuke、Yoshikai Yasunobu
- Journal Title
  
  Immunology Letters
  
  Volume: 191 Pages: 40-46
- DOI
  10.1016/j.imlet.2017.09.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08740, KAKENHI-PLANNED-16H06496
[Journal Article] Naturally occurring PD-1+ memory phenotype CD8 T cells belong to nonconventional CD8 T cells and are cyclophosphamide-sensitive regulatory T cells2013
- Author(s)
  Sakuraba K, Shibata K, Iwamoto Y, Yoshikai Y, Yamada H
- Journal Title
  
  J Immunol
  
  Volume: 190 Pages: 1560-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] Close link between development and function of gammadelta T cells2012
- Author(s)
  Shibata K., et al
- Journal Title
  
  Microbiology and immunology
  
  Volume: (印刷中) Issue: 4 Pages: 217-227
- DOI
  10.1111/j.1348-0421.2012.00435.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] Innate memory phenotype CD4+ T cells play a role in early protection against infection by Listeria monocytogenes in a CD30L-dependent manner2011
- Author(s)
  Umeda K, Sun X, Guo Y, Yamada H, Shibata K, Yoshikai Y.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 55 Pages: 645-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] nnate memory phenotype CD4+ T cells play a role in early protection against infection with Listeria monocytogenes in a CDsoLdependent manner2011
- Author(s)
  Umeda K., Sun X. Guo Y., Yamada H., Shibata K. and Yoshikai Y
- Journal Title
  
  Micrbiol. Immunol
  
  Volume: 55 Pages: 645-56
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] IL-17 production by gammadelta T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer2011
- Author(s)
  Takeuchi A, Dejima T, Yamada H, Shibata K, Nakamura R, Eto M, Nakatani T, Naito S, Yoshikai Y.
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Pages: 246-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] Notch-Hes1 pathway is required for the development of IL-17-producing Yδ T cells2011
- Author(s)
  K.Shibata
- Journal Title
  
  Blood
  
  Volume: 118 Issue: 3 Pages: 586-593
- DOI
  10.1182/blood-2011-02-334995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21240028, KAKENHI-PROJECT-21390130, KAKENHI-PROJECT-21390297, KAKENHI-PUBLICLY-22021032, KAKENHI-PLANNED-22118004, KAKENHI-PROJECT-22790468
[Journal Article] Protective role of naturally occurring interleukin-17A-producing gammadelta T cells in the lung at the early stage of systemic candidiasis in mice2011
- Author(s)
  Dejima T, Shibata K, Yamada H, Hara H, Iwakura Y, Naito S, Yoshikai Y
- Journal Title
  
  Infect Immun
  
  Volume: 79 Pages: 4503-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] A protective role of naturally occurring ILliAproducing 76 T cells in the lung at the early stage of systemic candidiasis in mice2011
- Author(s)
  Dejima T., Shibata K., Yamada H., Hara H., Iwakura Y., Naito S. and Yoshikai Y.
- Journal Title
  
  Infect. Immun
  
  Volume: 79 Pages: 4503-10
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Notch-Hesl pathway is required for thedevelopment of ILliproducing y8 T cells2011
- Author(s)
  Shibata K., Yamada H., Sate T., Dejima S., Nakamura M., , Ikawa T., Hara H., Yamasaki S., Kageyama R., Iwakura Y., Kawamoto H., Ton H. and Yoshikai Y.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 586-93
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] IL-li production by 78 T cells is important for the antitumor effect of Mycobacterium bovis bacillus CalmetteGuerin treatment against bladder cancer2011
- Author(s)
  Takeuchi A., Dejima T., Yamada H., Shibata K., Nakamura R., Eta M., Nakatani T., Naito S., and Yoshikai Y
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 41 Pages: 246-51
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] CD30 ligand is a target for a novel biological therapy against allergic rhinitis2011
- Author(s)
  Fuchiwaki T., Sun X., Yamada H., Shibata K Muta H., Podack E. R. Kawauchi H and Yoshikai Y
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 41 Pages: 2947-54
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Notch-Hes1 pathway is required for the development of IL-17-producing gammadelta T cells2011
- Author(s)
  Shibata K, Yamada H, Sato T, Dejima T, Nakamura M, Ikawa T, Hara H, Yamasaki S, Kageyama R, Iwakura Y, Kawamoto H, Toh H, Yoshikai Y.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 586-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice2011
- Author(s)
  Fuchiwaki T, Sun X, Fujimura K, Yamada H, Shibata K, Muta H, Podack ER, Kawauchi H, Yoshikai Y.
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Pages: 2947-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] A critical role of CDso ligand in THli differentiation2010
- Author(s)
  Sun X. Yamada H., Shibata K., Muta H., Tani K., Podack E. R. Iwakura Y., and Yoshikai Y
- Journal Title
  
  J. Immunol
  
  Volume: 185 Pages: 2222-30
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Interleukin-ls is critical in the pathogenesis of influenza A virusinduced acute lung injury2010
- Author(s)
  Nakamura R., Maeda N., Shibata K. Yamada H., Kase T. and Yoshikai Y.
- Journal Title
  
  J. viral
  
  Volume: 84 Pages: 5574-82
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] CDso ligand is a target for a novel biological therapy against colitis associated with Th17 responses2010
- Author(s)
  Sun X. Yamada H., Shibata K., Muta H., Tani K., Podack E. R. Iwakura Y. and Yoshikai Y.
- Journal Title
  
  J. Immunol
  
  Volume: 185 Pages: 7671-80
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Dual specificity phosphatasel6 is a negative regulator of INK activity in T cells2010
- Author(s)
  Tang C., Yamada H., Shibata K., Yoshida S., Wajjwalku W., and Yoshikai Y.
- Journal Title
  
  Microbiol. Immunol
  
  Volume: 54 Pages: 105-11
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y.
- Journal Title
  
  J Immunol
  
  Volume: 185 Pages: 2222-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] CD30 ligand is a target for a novel biological therapy against colitis associated with Th17 responses2010
- Author(s)
  Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y
- Journal Title
  
  J Immunol
  
  Volume: 185 Pages: 7671-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790468
[Journal Article] Functions of ILliproducing y8 T cells The Open2009
- Author(s)
  Shibata K. Yoshikai Y.
- Journal Title
  
  Immunology Journal
  
  Volume: 2 Pages: 151-155
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 42009
- Author(s)
  Takeuchi A., Kamiryou Y., Yamada H., Eta M., Shibata K., Haruna K., Naito S., and Yoshikai Y.
- Journal Title
  
  Int. Immunopharma.
  
  Volume: 9 Pages: 1562-7
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] Exogenous IL-15 protects CD8+ T Cell Contraction after BCG vaccination but fails to provide protection against subsequent infection with Mycobacterium tuberculosis2009
- Author(s)
  Tang C., Yamada H., Shibata K., Yoshida S., Wajjwalku W., and Yoshikai Y.
- Journal Title
  
  J. Leuko Biol
  
  Volume: 86 Pages: 187-94
- Data Source
  KAKENHI-PROJECT-21390130
[Journal Article] 炎症と免疫2009
- Author(s)
  柴田健輔., 山田久方, 吉開泰信.
- Journal Title
  
  IL-17とγδ型Tリンパ球
- Data Source
  KAKENHI-PROJECT-21390130
[Patent] 免疫細胞特異的活性化剤の発見2019
- Inventor(s)
  柴田健輔
- Industrial Property Rights Holder
  国立大学法人山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16K08740
[Presentation] Protective roles of MAIT cells in autoimmune uveitis2024
- Author(s)
  Kensuke Shibata、Chihiro Murata、Satoshi Yamana、Eiichi Hasegawa、Nobuyo Yawata、Atsunobu Takeda、Koh-Hei Sonoda
- Organizer
  CD1-MR1 EMBO Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18330
[Presentation] Protective roles of MAIT cells in autoimmune uveitis2024
- Author(s)
  Kensuke Shibata, Chihiro Murata, Satoshi Yamana, Eiichi Hasegawa, Nobuyo Yawata, Atsunobu Takeda, Koh-Hei Sonoda
- Organizer
  CD1-MR1 EMBO Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04784
[Presentation] 粘膜関連T細胞が認識するガン由来抗原の同定2023
- Author(s)
  柴田健輔
- Organizer
  ITAM workshop
- Data Source
  KAKENHI-PROJECT-20K07539
[Presentation] MAIT細胞は自己免疫性眼疾患に対して治療効果を有する2022
- Author(s)
  柴田健輔
- Organizer
  EMBO workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07539
[Presentation] 細胞内寄生性病原細菌Francisella tularensisは代謝経路を変化させることで適応免疫から回避する2022
- Author(s)
  柴田健輔
- Organizer
  第51回日本免疫学会
- Data Source
  KAKENHI-PROJECT-20K07539
[Presentation] Mucosal-associated invariant T cells have therapeutic potential against autoimmune uveitis.2021
- Author(s)
  Kensuke Shibata
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-20K07539
[Presentation] MR1T細胞認識抗原の探索2019
- Author(s)
  柴田健輔、藤原愛紗、石川絵里、本園千尋、山崎晶、園田康平
- Organizer
  7th ITAM workshop
- Data Source
  KAKENHI-PROJECT-16K08740
[Presentation] ヒトMAIT細胞認識抗原の探索2018
- Author(s)
  藤原愛紗、柴田健輔、石川絵里、本園千尋、山崎晶、園田康平
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-16K08740
[Presentation] Innate-like T cells for health and disease2017
- Author(s)
  Kensuke Shibata
- Organizer
  International conference of Korean Society for Biochemistry and Molecular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08740
[Presentation] 自己免疫疾患発症に関わるabT細胞サブセットの同定と機能解析2016
- Author(s)
  柴田健輔
- Organizer
  京都T cell conference
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-16K08740
[Presentation] Intrathymic programming of murine gd T cells by Notch signaling2012
- Author(s)
  柴田健輔
- Organizer
  gd T cell conference
- Place of Presentation
  フライブルグ、ドイツ
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Notch-RBP-Jκ-IL-7 receptor alpha axis is essential for the maintenance of IL-17-producing γδ T cells2012
- Author(s)
  柴田健輔
- Organizer
  日本免疫学会
- Place of Presentation
  神戸, 日本
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Notch-RBP-Jκ-IL-7 receptor alpha axis is essential for the maintenance of IL-17-producing γδ T cells2012
- Author(s)
  柴田健輔
- Organizer
  日本免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Notch、γδTCRシグナルによるγδ T細胞機能分化制御2012
- Author(s)
  柴田健輔
- Organizer
  日本生体防御学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] NotchシグナルはIL-17産生γδ T細胞の維持に必須である2012
- Author(s)
  柴田健輔
- Organizer
  京都 T cell conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Intrathymic programming of murine gd T cells by Notch signaling2012
- Author(s)
  柴田健輔
- Organizer
  gd T cell conference
- Place of Presentation
  Freiburg, Germany
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] IL-7-receptor-α-mediated signaling is required for the development of naturally occurring IL-17-producing γδ T cells in the adult thymus2011
- Author(s)
  中村真隆、柴田健輔
- Organizer
  日本免疫学会
- Place of Presentation
  千葉, 日本
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Notchr-Hes1経路は自然発生IL-17産生γδT細胞分化に必要である2011
- Author(s)
  柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] IL-7-receptor a rediated signaling is required for the devel opnent of naturally occurri ng IL-17-producingγδT cells in the adult thymus2011
- Author(s)
  Nakamura Masataka, Shibata Kensuke, Yanada Hsakata, Ikuta Koichi, Yoshikai Yasunobu
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] 自然発生IL 17産生γδT細胞活性化におけるCDBOLigandの役割2011
- Author(s)
  孫遜、郭穎、黄銀霞、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] Naturally occurring IL-17-producing γδ T cells commit at the DN2 stage of mouse fetal thymus in Notch-dependent manner2011
- Author(s)
  柴田健輔
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Naturally occurri ng IL-17-producingγδT cells commit at the DN2 stage of mouse fetal thymus in Notch dependent nanner2011
- Author(s)
  Shibata kensuke, Yanada Hsakata, Yoshi kai Yasunobu
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] 自然発生IL 17産生γδT細胞機能制御機構の解析2011
- Author(s)
  中村真隆、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] 胸腺におけるγδT細胞機能獲得機構の解析2011
- Author(s)
  柴田健輔
- Organizer
  京都T cell conference
- Place of Presentation
  京都
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Notch-Hes1経路は自然発生IL-17産生γδT細胞分化に必要である2011
- Author(s)
  柴田健輔
- Organizer
  日本生体防御学会
- Place of Presentation
  沖縄
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] Candi da al bi cans感染防御におけるIL-17産生γδT細胞の役割2011
- Author(s)
  出嶋卓、柴田健輔、山田久方、吉開泰信
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] The Basic Helix-Loop-Helix protein HES1 controls the differentiation of naturally occurring interleukin (IL)-17-producing γδ T cells.2010
- Author(s)
  Kensuke Shibata
- Organizer
  International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] The Basic Helix-Loop-Helixprotein HES1, is required for the differentiation of naturally occurring2010
- Author(s)
  Kensuke Shibata, Hsakata Yanada, Tetsuya Sato, Hromitsu Hara, Sho Yanasaki, Ryoichiro Kageyana, Yoichiro Iwakura, Hroyuki Toh and Yasunobu Yoshi kai
- Organizer
  interleukin(IL)-17-producing gd T cells. gd Tcell conference, Kiel
- Place of Presentation
  G rnanv
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21390130
[Presentation] The Basic Helix-Loop-Helix protein HES1, is required for the differentiation of naturally occurring interleukin(IL)-17-producing gd T cells2010
- Author(s)
  柴田健輔
- Organizer
  gd T cell conferenc
- Place of Presentation
  Kiel, Germany
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] The basic Helix-loop-Helix protein HES1は自然発生IL-17産生γδ T細胞分化に必要である2010
- Author(s)
  柴田健輔
- Organizer
  生体防御学会
- Place of Presentation
  仙台市
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] The Basic Helix-Loop-Helix protein HES1 controls the differentiation of naturally occurring interleukin (IL)-17-producing γδ T cells2010
- Author(s)
  柴田健輔
- Organizer
  14th International Congress Of Immunology
- Place of Presentation
  神戸、日本
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] The Basic Helix-Loop-Helix protein HES1, is required for the differentiation of naturally occurring interleukin (IL)-17-producing γδ T cells.2010
- Author(s)
  Kensuke Shibata
- Organizer
  γδ T cell conference
- Place of Presentation
  Kiel, Germany
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22790468
[Presentation] BCG膀胱内注入療法の抗腫瘍効果にはγδT細胞によるIL 17産生が重要である2009
- Author(s)
  武内在雄,山田久方,柴田健輔,吉開泰信
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-21390130

1. Seiki Makoto (50226619)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. 園田康平 (10294943)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. 永野浩昭 (10294050)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 硲彰一 (50253159)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 浅岡洋一 (10436644)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MUTSUNORI SHIRAI (20196596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. Hasegawa Eiichi (70636521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 山崎晶 (40312946)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. 武田篤信 (40560313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 宮本達雄 (40452627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. YOSHIKAI Yasunobu (90158402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMADA Hsakata (20363369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
13. Murakami Yusuke (50634995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 池田康博 (20380389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田尾嘉誉 (30425417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 浅井義之 (00415639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 徳永雅之 (10845043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 元岡大祐 (10636830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 中山二郎 (40217930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 真野純一 (50243100)

# of Collaborated Projects: 1 results

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21. 田口昭彦 (20634744)

# of Collaborated Projects: 1 results

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22. 太田康晴 (60448280)

# of Collaborated Projects: 1 results

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23. 富永直臣 (90891507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 八幡信代 (90315812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OGAWA Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 吉開康信

# of Collaborated Projects: 0 results

# of Collaborated Products: 19 results
27. 和泉自泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 本園千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Kensuke 柴田 健輔

SHIBATA Kensuke 柴田 健輔

SHBATA Kensuke 柴田 健輔

Research Projects

Research Products

Co-Researchers

空間遺伝子発現解析による自己免疫性ぶどう膜炎後に誘導される視覚保護機構の解明Principal Investigator

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共生微生物由来代謝産物を感知するMAIT細胞による功と罪Principal Investigator

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自己分子としての共生微生物由来代謝産物の免疫学的意義の解明Principal Investigator

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Development of a treatment strategy for autoimmune uveitis using metabolites derived from intestinal bacteriaPrincipal Investigator

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Development of innovative cancer immunotherapy targeting metabolites applicable to all patientsPrincipal Investigator

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Elucidation of molecular mehcanisms of autoimmune pancreatitisPrincipal Investigator

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Shibata Kensuke 柴田健輔

SHIBATA Kensuke 柴田健輔

SHBATA Kensuke 柴田健輔