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Yasuda Shumpei  安田 俊平

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YASUDA Shumpei  安田 俊平

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Researcher Number 50534012
Other IDs
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員
2013 – 2019: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員
Review Section/Research Field
Principal Investigator
Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Except Principal Investigator
Laboratory animal science
Keywords
Principal Investigator
マウス / 難聴 / 遺伝学 / 加齢性難聴 / 遺伝性難聴 / C57BL/6J / MSM/Ms / マウス遺伝学 / DPOAE / ABR … More / ゲノムマッピング / scRNA-seq / 順遺伝学 / 外有毛細胞 / シングルセルRNA-seq / 極性異常 / 不動毛 / 平面内細胞極性 / Usher症候群 / 選択的スプライシング / 遺伝子 / Whirlin / whirlin … More
Except Principal Investigator
対立遺伝子発現量 / 遺伝子発現 / カドヘリン23 / コンソミックマウス / アレル発現量比較 / ゲノム編集 / 難聴 / 遺伝学 / 実験動物学 Less
  • Research Projects

    (5 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (9 People)
  •  Identification and functional analysis of genes suppressing the onset of age-related hearing loss in the Japanese wild-derived inbred MSM/Ms micePrincipal Investigator

    • Principal Investigator
      YASUDA Shumpei
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Identification of novel genes responsible for sex differences of age-related hearing lossPrincipal Investigator

    • Principal Investigator
      YASUDA Shumpei
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Function of scaffold proteins in the polarization of stereocilia on inner ear hair cellsPrincipal Investigator

    • Principal Investigator
      YASUDA Shumpei
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Identification of genetic risk factors and phenotypic rescue of deaf mutant mice based on technological innovations of the forward genetics approach

    • Principal Investigator
      KIKKAWA Yoshiaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  To elucidate the mechanism of stereocilia development based on functions of whirlin isoformsPrincipal Investigator

    • Principal Investigator
      YASUDA Shumpei
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

  • [Book] An Excursus into Hearing Loss2018

    • Author(s)
      Yasuda SP, Miyasaka Y, Kikkawa Y
    • Publisher
      InTech
    • ISBN
      9781789232127
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Journal Article] Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSMMs Mice2022

    • Author(s)
      Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, Toyoyuki Takada, Toshihiko Shiroishi, Ryo Kominami and Yoshiaki Kikkawa
    • Journal Title

      Biomedicines

      Volume: 10 Issue: 9 Pages: 2221-2221

    • DOI

      10.3390/biomedicines10092221

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09643, KAKENHI-PROJECT-21K19196, KAKENHI-PROJECT-22K20739, KAKENHI-PROJECT-20K06466
  • [Journal Article] c.753A>G genome editing of a Cdh23ahl allele delays age-related hearing loss and degeneration of cochlear hair cells in C57BL/6J mice.2020

    • Author(s)
      Yasuda SP, Seki Y, Suzuki S, Ohshiba Y, Hou X, Matsuoka K, Wada K, Shitara H, Miyasaka Y, Kikkawa Y
    • Journal Title

      Hear Res

      Volume: 389 Pages: 107926-107926

    • DOI

      10.1016/j.heares.2020.107926

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06466, KAKENHI-PROJECT-18K09364
  • [Presentation] Two loci, ahl3 and ahl10, contribute to age-related hearing loss resistance in the Japanese wild-derived inbred MSM/Ms mice2023

    • Author(s)
      Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, Toyoyuki Takada, Toshihiko Shiroishi, Ryo Kominami, and Yoshiaki Kikkawa
    • Organizer
      36th International Mammalian Genome Conference (IMGC2023)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] MSM/Msマウス由来ahl10ゲノム領域の置換はC57BL/6Jマウスの加齢性難聴の発症を長期的に抑制する2023

    • Author(s)
      安田俊平,関 優太,侯 雪含,吉川欣亮
    • Organizer
      第33回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] MSM マウスの加齢性難聴抵抗性の遺伝学的解明2023

    • Author(s)
      安田俊平
    • Organizer
      第33回モロシヌス研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] ahl3およびahl10遺伝子座は日本産野生マウス由来MSM系統の加齢性難聴抵抗性に関与する2022

    • Author(s)
      安田俊平,宮坂勇輝,侯 雪含,小原 央,設楽浩志,関 優太,松岡邦枝,髙橋あい,若井恵里,日比野浩,高田豊行,城石俊彦,木南 凌,吉川欣亮
    • Organizer
      日本遺伝学会第94回大会
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] MSM/Msマウスのahl10遺伝子座の加齢性難聴発症抑制効果の検証2022

    • Author(s)
      安田俊平,関 優太,侯 雪含,高田豊行,城石俊彦,吉川欣亮
    • Organizer
      第69回 日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] C57BL/6マウスの高周波音域の加齢性難聴発症を抑制する新規遺伝子座の同定2021

    • Author(s)
      安田俊平, 関 優太, 松岡邦枝, 侯 雪含, 吉川欣亮
    • Organizer
      第31回日本耳科学会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09643
  • [Presentation] BALB/c亜系統を用いた新規難聴遺伝子の探索2019

    • Author(s)
      安田俊平,関 優太,松岡邦枝,吉川欣亮
    • Organizer
      第29回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-18K09364
  • [Presentation] カドヘリン23 のc.753 遺伝子型が異なるC57BL/6Jマウス間の加齢に伴う聴力表現型の比較2017

    • Author(s)
      鈴木沙理,宮坂勇輝,関 優太,安田俊平,松岡邦枝,設楽浩志,吉川欣亮
    • Organizer
      第64回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] 早発性難聴モデルマウスの遺伝要因の解析2017

    • Author(s)
      鈴木沙理,松岡邦枝,関 優太,安田俊平,吉川欣亮
    • Organizer
      生理学研究所研究会
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] B6-MSMコンソミックマウスを用いた新規加齢性難聴関連遺伝子の探索2017

    • Author(s)
      安田俊平, 小原 央, 鈴木沙理, 和田健太, 西藤泰昌, 高田豊行, 城石俊彦, 吉川欣亮
    • Organizer
      第30回モロシヌス研究会
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] マウス12番染色体上に存在する新規加齢性難聴修飾遺伝子の探索2017

    • Author(s)
      安田俊平,小原 央,鈴木沙理,高田豊行,城石俊彦,吉川欣亮
    • Organizer
      第64回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] 近交系の聴力差の遺伝的要因を探る2017

    • Author(s)
      吉川欣亮,宮坂勇輝,安田俊平,設楽浩志
    • Organizer
      2017年度遺伝研研究会「マウスとラットで拓く新しい比較実験動物学」
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] Intersubspecific replacement across a broad genomic region of chromosome 12 reduces symptoms of early-onset high-frequency hearing loss in C57BL/6J mice.2016

    • Author(s)
      Yasuda SP, Obara Y, Suzuki S, Wada K, Nishito Y, Takada T, Shiroishi T, Kikkawa Y
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] hfhl4, a novel locus on mouse chromosome 12 affects early-onset, high frequency hearing loss.2016

    • Author(s)
      Yasuda SP, Obara Y, Suzuki S, Wada K, Nishito Y, Takada T, Shiroishi T, Kikkawa Y
    • Organizer
      Inner Ear Biology Workshop 2016
    • Place of Presentation
      Le Corum(Montpellier, France)
    • Year and Date
      2016-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] 成熟内耳におけるLrrc30の高発現とマウス加齢性難聴抑制効果の関連2015

    • Author(s)
      宮坂勇輝, 安田俊平, 城石俊彦, 木南 凌, 吉川欣亮
    • Organizer
      第29回モロシヌス研究会
    • Place of Presentation
      かんぽの宿有馬(兵庫県・神戸市)
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] マウス成熟内耳におけるLrrc30の高発現と加齢性難聴抑制効果の関連を探る!2015

    • Author(s)
      宮坂勇輝,安田俊平,関 優太,松岡邦枝,日比野浩,木南 凌,吉川欣亮
    • Organizer
      第62回実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府・京都市)
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15H04291
  • [Presentation] Characterization of Expression and Transcriptional Regulation in Short Isoform of the Deafness Gene Whirlin in Mice2014

    • Author(s)
      Shumpei P. Yasuda, Yoshiaki Kikkawa
    • Organizer
      Inner Ear Biology Workshop 2014 in Kyoto
    • Place of Presentation
      国立京都国際会館 (京都府・京都市)
    • Year and Date
      2014-11-03
    • Data Source
      KAKENHI-PROJECT-25861604
  • [Presentation] 難聴責任遺伝子Whirlinアイソフォームの発現解析と選択的プロモーターの同定2014

    • Author(s)
      安田俊平, 吉川欣亮
    • Organizer
      第11回北海道実験動物研究会(HALAS)学術集会
    • Place of Presentation
      北海道大学大学院獣医学研究科 (北海道・札幌市)
    • Year and Date
      2014-07-26
    • Data Source
      KAKENHI-PROJECT-25861604
  • [Presentation] 難聴責任遺伝子Whirlinのshortアイソフォームの組織特異的発現プロセスと転写制御2014

    • Author(s)
      安田俊平, 吉川欣亮
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター (北海道・札幌市)
    • Year and Date
      2014-05-17
    • Data Source
      KAKENHI-PROJECT-25861604
  • [Presentation] 難聴責任遺伝子Whirlinのlongおよびshort型アイソフォームの異なった発現制御

    • Author(s)
      安田俊平,吉川欣亮
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25861604
  • [Presentation] 難聴責任遺伝子Whirlinの2つのアイソフォームの異なった発現制御

    • Author(s)
      安田俊平,Steve Brown,吉川欣亮
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-25861604
  • [Presentation] 難聴責任遺伝子Whirlinのlongおよびshort型アイソフォームの異なった発現制御

    • Author(s)
      安田俊平,吉川欣亮
    • Organizer
      日本遺伝学会第85回大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25861604
  • 1.  KIKKAWA Yoshiaki (20280787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  SHITARA Hiroshi (90321885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  SEKI Yuta (10615636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  高田 豊行 (20356257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  宮坂 勇輝 (30778098)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 6.  OBARA Yo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  SUZUKI Sari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  WADA Kenta
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  松岡 邦枝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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