Ide Satoru 井手聖

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IDE Satoru 井手聖

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Researcher Number	50534567
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 助教 2025: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 研究員 2025: 国立遺伝学研究所, 遺伝メカニズム研究系, 外来研究員(客員研究員)
Affiliation (based on the past Project Information) *help	2024: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 研究員 2022 – 2023: 国立遺伝学研究所, 遺伝メカニズム研究系, 外来研究員(客員研究員) 2018 – 2023: 国立遺伝学研究所, 遺伝メカニズム研究系, 助教 2015 – 2016: 国立遺伝学研究所, 構造遺伝学研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 45010:Genetics-related / Transformative Research Areas, Section (III) / Basic Section 43050:Genome biology-related / Biological Sciences / Genetics/Chromosome dynamics Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator クロマチン / 核小体 / 液ー液相分離 / リボソームRNA遺伝子 / コンデンセート / 遺伝疾患 / RNAポリメラーゼI / 転写 / rRNA遺伝子 / 一分子イメージング … More / rRNA合成 / 液-液相分離 / 試験管内再構成 / 相分離 / 非コードRNA / ノンコーディングRNA / 相転移 / 神経疾患 / 希少疾患 / プロテオミクス / 人工核酸 / 遺伝子サイレンシング / リボソームRNA遺伝子（rDNA） / 液滴 / RNAポリメラーゼ / サイレンシング … More Except Principal Investigator 分子間相互作用 / 蛍光1分子観察 / 液-液相分離 / 蛍光ライブイメージング / 蛍光異方性 / 蛍光偏光 / 染色体 / 液液相分離 Less

A novel fluorescence anisotropy imaging for imaging nano-scale LLPS in living cells
- Principal Investigator
  
  谷知己
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
I型RNAポリメラーゼがつくる非ドメイン型バイオポリマーの探索と機能解析Principal Investigator
- Principal Investigator
  
  井手聖
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  National Institute of Genetics
Spatial regulation of ribosomal RNA transcription by phase separation and transitionPrincipal Investigator
- Principal Investigator
  
  井手聖
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
  National Institute of Genetics
Transcriptional suppression of ribosomal DNA with phase separationPrincipal Investigator
- Principal Investigator
  
  Ide Satoru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  National Institute of Genetics
Dissection of nucleolar silent chromatin structure by proteomics and single- molecule imagingPrincipal Investigator
- Principal Investigator
  
  IDE Satoru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  National Institute of Genetics
rRNA遺伝子上での包括的なDNA-タンパク相互作用情報の抽出基盤の構築Principal Investigator
- Principal Investigator
  
  井手聖
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 現代化学増刊46『相分離生物学の全貌』白木賢太郎 (編集)2020
- Author(s)
  井手聖, 前島一博
- Total Pages
  6
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-18K06187
[Book] 教科書を書き換えろ！染色体の新常識2018
- Author(s)
  井手　聖、平野　達也、胡桃坂　仁志
- Total Pages
  214
- Publisher
  羊土社
- ISBN
  9784758103749
- Data Source
  KAKENHI-PROJECT-18K06187
[Book] 実験医学別冊「エピジェネティクススタンダード」2017
- Author(s)
  井手聖、牛島俊和、眞貝洋一、塩見春彦
- Total Pages
  398
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-15H01361
[Book] 実験医学別冊「エピジェネティクス実験スタンダード」2017
- Author(s)
  井手聖、牛島俊和、眞貝洋一、塩見春彦
- Total Pages
  398
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K18580
[Journal Article] POLR1A variants underlie phenotypic heterogeneity in neural, craniofacial, and cardiac anomalies2023
- Author(s)
  Smallwood, K., Saitoh, N., Weaver, K. N., et al.
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 110, 1_17, Issue: 5 Pages: 809-825
- DOI
  10.1016/j.ajhg.2023.03.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03520, KAKENHI-PLANNED-18H05531, KAKENHI-PROJECT-23K21326, KAKENHI-PROJECT-22K19466, KAKENHI-PROJECT-23H00411
[Journal Article] Condensed but liquid-like domain organization of active chromatin regions in living human cells2023
- Author(s)
  Nozaki Tadasu、Shinkai Soya、Ide Satoru、Higashi Koichi、Tamura Sachiko、Shimazoe Masa A.、Nakagawa Masaki、Suzuki Yutaka、Okada Yasushi、Sasai Masaki、Onami Shuichi、Kurokawa Ken、Iida Shiori、Maeshima Kazuhiro
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 14 Pages: 1-19
- DOI
  10.1126/sciadv.adf1488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05763, KAKENHI-PROJECT-23K21326, KAKENHI-PROJECT-23KJ0996, KAKENHI-PUBLICLY-23H04297, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-22H00406
[Journal Article] Chromatin behavior in living cells: lessons from single-nucleosome imaging and tracking.2022
- Author(s)
  Ide, S., Tamura, S., Maeshima, K.
- Journal Title
  
  BioEssays
  
  Volume: 44 Issue: 7 Pages: 2200043-2200043
- DOI
  10.1002/bies.202200043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02453, KAKENHI-PROJECT-23K21326, KAKENHI-PLANNED-20H05936, KAKENHI-PUBLICLY-22H05606
[Journal Article] 核内構造体と液-液相分離～核小体と転写コンデンセートを中心に～2022
- Author(s)
  井手聖 , 前島一博
- Journal Title
  
  生化学特集「今，解き明かされつつある液-液相分離による生体機能制御」椎名伸之、奥野浩行編
  
  Volume: 94 Pages: 485-493
- Data Source
  KAKENHI-PUBLICLY-22H05606
[Journal Article] 物性から迫るクロマチンの実像―相分離するクロマチンは液体か?固体か?2022
- Author(s)
  島添將誠 , 井手聖 , 前島一博
- Journal Title
  
  実験医学増刊号セントラルドグマの新常識
  
  Volume: 40 Pages: 32-41
- Data Source
  KAKENHI-PUBLICLY-22H05606
[Journal Article] Hexanediol Condenses Chromatin2021
- Author(s)
  伊藤優志，井手聖, 前島一博
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 61 Issue: 6 Pages: 385-388
- DOI
  10.2142/biophys.61.385
- NAID
  130008120205
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02453, KAKENHI-PROJECT-23K21326, KAKENHI-PLANNED-20H05936
[Journal Article] Telomere-specific chromatin capture using a pyrrole-imidazole polyamide probe for the identification of proteins and non-coding RNAs2021
- Author(s)
  Ide Satoru、Sasaki Asuka、Kawamoto Yusuke、Bando Toshikazu、Sugiyama Hiroshi、Maeshima Kazuhiro
- Journal Title
  
  Epigenetics & Chromatin
  
  Volume: 14 Issue: 1 Pages: 46-46
- DOI
  10.1186/s13072-021-00421-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15225, KAKENHI-PROJECT-21H02453, KAKENHI-PROJECT-23K21326, KAKENHI-PLANNED-20H05936
[Journal Article] 1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells2021
- Author(s)
  Itoh Yuji、Iida Shiori、Tamura Sachiko、Nagashima Ryosuke、Shiraki Kentaro、Goto Tatsuhiko、Hibino Kayo、Ide Satoru、Maeshima Kazuhiro
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 4 Pages: e202001005-e202001005
- DOI
  10.26508/lsa.202001005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06594, KAKENHI-PROJECT-20J00572, KAKENHI-PROJECT-18K06187, KAKENHI-PLANNED-20H05936
[Journal Article] Transcriptional suppression of ribosomal DNA with phase separation.2020
- Author(s)
  Ide, T., Ochi, H., Imai, R., Maeshima, K.
- Journal Title
  
  Science Advances.
  
  Volume: 6 Issue: 42
- DOI
  10.1126/sciadv.abb5953
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05273, KAKENHI-PROJECT-18K06187
[Journal Article] SETDB1 dependent heterochromatin stimulates alternative lengthening of telomeres2019
- Author(s)
  Mathilde Gauchier、Sophie Kan、Amandine Barral、Sandrine Sauzet、 Eneritz Agirre、Erin Bonnell、Nehme. Saksouk、Teresa K. Barth、Satoru Ide、Serge Urbach、Raymund J. Wellinger、Reini F. Luco、Axel Imhof、Jerome Dejardin
- Journal Title
  
  Science Advances
  
  Volume: 5 Issue: 5
- DOI
  10.1126/sciadv.aav3673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06187
[Journal Article] Dynamic chromatin organization without the 30-nm fiber2019
- Author(s)
  Maeshima Kazuhiro、Ide Satoru、Babokhov Michael
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 58 Pages: 95-104
- DOI
  10.1016/j.ceb.2019.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06187, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05273
[Journal Article] Targeting 24 bp within Telomere Repeat Sequences with Tandem Tetramer Pyrrole-Imidazole Polyamide Probes.2016
- Author(s)
  Kawamoto, Y.,Sasaki, A., Chandrana, A., Hashiya, K., Ide, S., Bando, T., Maeshima, K., Sugiyama, H.
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 138 Issue: 42 Pages: 14100-14107
- DOI
  10.1021/jacs.6b09023
- NAID
  120006462489
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01361, KAKENHI-PROJECT-16H06356, KAKENHI-PROJECT-15J00928, KAKENHI-PROJECT-16H04746
[Journal Article] Telomere Visualization in Tissue Sections Using Pyrrole-Imidazole Polyamide Probes.2016
- Author(s)
  Sasaki, A., Ide, S., Kawamoto, Y., Bando, T., Murata, Y., Shimura, M., Yamada, K., Hirata, A., Nokihara, K., Hirata, T., Sugiyama, H., Maeshima, K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 29261-29261
- DOI
  10.1038/srep29261
- NAID
  120005774690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01361, KAKENHI-PUBLICLY-15H01453, KAKENHI-PROJECT-16H06356, KAKENHI-PROJECT-15J00928, KAKENHI-PROJECT-15K10124, KAKENHI-PROJECT-16H04659, KAKENHI-PROJECT-16H04746, KAKENHI-PROJECT-15K14323
[Journal Article] Liquid-like behavior of chromatin2016
- Author(s)
  Kazuhiro Maeshima, Satoru Ide, Kayo Hibino and Masaki Sasai
- Journal Title
  
  Current Opinion in Genetics and Development
  
  Volume: 37 Pages: 36-45
- DOI
  10.1016/j.gde.2015.11.006
- NAID
  120005822509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26610130, KAKENHI-PUBLICLY-15H01361, KAKENHI-PLANNED-23115005
[Presentation] Telomere-specific chromatin capture using a pyrrole-imidazole polyamide probe for the identification of proteins and non-coding RNAs2022
- Author(s)
  Satoru Ide, Asuka Sasaki, Yusuke Kawamoto, Toshikazu Bando, Hiroshi Sugiyama, Kazuhiro Maeshima
- Organizer
  第74回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 核小体サブコンパートメントの相分離2022
- Author(s)
  井手聖
- Organizer
  第45回分子生物学会年会ワークショップ『転移因子コードによる核内相分離構造の理解』
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05606
[Presentation] Phase separation and transition of nucleolar condensate2022
- Author(s)
  Satoru Ide
- Organizer
  金沢大学新学術創成研究機構ナノマテリアル研究所異分野融合セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05606
[Presentation] Phase separation and transition of nucleolar condensate2022
- Author(s)
  Satoru Ide
- Organizer
  The NIG International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 核小体サブコンパートメントの相分離2022
- Author(s)
  井手聖、村山泰斗、前島一博
- Organizer
  第45回分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] Phase separation of the subnucleolar compartments, the fibrillar centers2021
- Author(s)
  Satoru Ide, Yasuto Murayama, Ryosuke Imai, Hiroko Ochi, Kazuhiro Maeshima
- Organizer
  第44回分子生物学会年会　ワークショップ『核小体から考える隔離系から混雑系の化学への発展』
- Invited
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 非膜オルガネラの転写制御2021
- Author(s)
  井手聖、今井亮輔、大地弘子、前島一博
- Organizer
  第30回日本バイオイメージング学会学術集会（Web会議）『非膜オルガネラをみる』
- Invited
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 相分離が駆動するリボソームRNA遺伝子の転写制御2021
- Author(s)
  井手聖、今井亮輔、大地弘子、前島一博
- Organizer
  生物物理学会サブグループ第1回ゲノム生物物理学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 相分離が駆動するリボソームRNA遺伝子の転写制御2021
- Author(s)
  井手聖、今井亮輔、大地弘子、前島一博
- Organizer
  第94回日本生化学会大会シンポジウム　『核小体の構造と機能の新たな発見』
- Invited
- Data Source
  KAKENHI-PROJECT-23K21326
[Presentation] 相分離に伴うリボソームRNA遺伝子の転写抑制2021
- Author(s)
  井手聖、今井亮輔、大地弘子、前島一博
- Organizer
  第38 回染色体ワークショップ/第19 回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K06187
[Presentation] 相分離に伴うリボソームRNA遺伝子の転写抑制2020
- Author(s)
  井手聖、今井亮輔、大地弘子、前島一博
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06187
[Presentation] Shut-down of ribosomal RNA transcription by liquid-like behavior of inactive RNA polymerase I2019
- Author(s)
  Satoru Ide
- Organizer
  第４２回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06187
[Presentation] Liquid droplets induced by aberrant RNA polymerase I in a craniofacial disorder lead to ribosome dysfunction2019
- Author(s)
  Satoru Ide
- Organizer
  3R&3C Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06187
[Presentation] 分子の動態から見えてきた転写装置と鋳型DNAが織り成す形2017
- Author(s)
  井手聖
- Organizer
  転写研究会・冬の若手ワークショップ2017
- Place of Presentation
  千葉県一宮シーサイドオーツカ
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PROJECT-15K18580
[Presentation] 分子の動態から見えてきた転写装置と鋳型DNAが織り成す形2017
- Author(s)
  井手聖
- Organizer
  転写研究会・冬の若手ワークショップ2017
- Place of Presentation
  千葉県一宮シーサイドオーツカ
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PUBLICLY-15H01361
[Presentation] 核小体クロマチンの動態と形態2016
- Author(s)
  井手聖
- Organizer
  遺伝研研究会「クロマチン・細胞核の動的構造変換とエピジェネティック制御」
- Place of Presentation
  国立遺伝学研究所
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K18580
[Presentation] rRNA遺伝子上での包括的なDNA-タンパク相互作用情報が照らし出す新たな転写制御2016
- Author(s)
  井手　聖
- Organizer
  転写研究会、冬の若手ワークショップ2016
- Place of Presentation
  山中湖ホテル清渓
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PROJECT-15K18580
[Presentation] rRNA遺伝子上での包括的なDNA-タンパク相互作用情報が照らし出す新たな転写制御2016
- Author(s)
  井手　聖
- Organizer
  転写研究会、冬の若手ワークショップ2016
- Place of Presentation
  山中湖ホテル清渓
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PUBLICLY-15H01361
[Presentation] 核小体クロマチンの動態と形態2016
- Author(s)
  井手聖
- Organizer
  遺伝研研究会「クロマチン・細胞核の動的構造変換とエピジェネティック制御」
- Place of Presentation
  国立遺伝学研究所
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PUBLICLY-15H01361
[Presentation] Transcription regulation of mammalian ribosomal RNA gene revealed by proteomic analysis for local chromatin configuration2015
- Author(s)
  井手　聖
- Organizer
  International Symposium on Chromatin Structure, Dynamics, and Function
- Place of Presentation
  淡路夢舞台
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01361
[Presentation] Transcription regulation of mammalian ribosomal RNA gene revealed by proteomic analysis for local chromatin configuration2015
- Author(s)
  井手　聖
- Organizer
  International Symposium on Chromatin Structure, Dynamics, and Function
- Place of Presentation
  淡路夢舞台
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18580
[Presentation] A method to dissect protein composition on regulatory DNA sequence and the future2015
- Author(s)
  井手　聖
- Organizer
  第３８回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K18580
[Presentation] A method to dissect protein composition on regulatory DNA sequence and the future2015
- Author(s)
  井手　聖
- Organizer
  第３８回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01361

1. 村山泰斗 (60531663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 谷知己 (80332378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 前島一博 (00392118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SHINKAI Soya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 斉藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 河本佑介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 笹井理生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 日比野佳代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ide Satoru 井手 聖

IDE Satoru 井手 聖

Research Projects

Research Products

Co-Researchers

A novel fluorescence anisotropy imaging for imaging nano-scale LLPS in living cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

I型RNAポリメラーゼがつくる非ドメイン型バイオポリマーの探索と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spatial regulation of ribosomal RNA transcription by phase separation and transitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transcriptional suppression of ribosomal DNA with phase separationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dissection of nucleolar silent chromatin structure by proteomics and single- molecule imagingPrincipal Investigator

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rRNA遺伝子上での包括的なDNA-タンパク相互作用情報の抽出基盤の構築Principal Investigator

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[Book] 現代化学増刊46『相分離生物学の全貌』白木 賢太郎 (編集)2020

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[Book] 教科書を書き換えろ！染色体の新常識2018

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[Book] 実験医学別冊「エピジェネティクススタンダード」2017

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[Book] 実験医学別冊「エピジェネティクス実験スタンダード」2017

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[Journal Article] POLR1A variants underlie phenotypic heterogeneity in neural, craniofacial, and cardiac anomalies2023

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[Journal Article] Condensed but liquid-like domain organization of active chromatin regions in living human cells2023

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[Journal Article] Chromatin behavior in living cells: lessons from single-nucleosome imaging and tracking.2022

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[Journal Article] 核内構造体と液-液相分離 ～核小体と転写コンデンセートを中心に～2022

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Ide Satoru 井手聖

IDE Satoru 井手聖

[Book] 現代化学増刊46『相分離生物学の全貌』白木賢太郎 (編集)2020

[Journal Article] 核内構造体と液-液相分離～核小体と転写コンデンセートを中心に～2022