Hosono Kunihiro 細野邦広

… Alternative Names

HOSONO Kunihiro 細野邦広

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Researcher Number	50537339
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 附属病院, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 横浜市立大学, 附属病院, 講師 2012 – 2015: 横浜市立大学, 附属病院, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 化学予防 / 大腸癌 / メトホルミン / 膵癌 / TNF-R1 / TNF-α / バイオマーカー

Chemoprevention of pancreatic cancer by metforminPrincipal Investigator
- Principal Investigator
  
  HOSONO Kunihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University
Increased TNF-R1 expression as a promising biomarker of human colorectal cancerPrincipal Investigator
- Principal Investigator
  
  HOSONO Kunihiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Chemopreventive effects of metformin for colon carcinogenesisPrincipal Investigator
- Principal Investigator
  
  HOSONO Kunihiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University

All 2021 2020 2019 2016 2014 2013 2012

All Journal Article Presentation

[Journal Article] Pathological Findings of the Host Immune Reaction in the Tumor Microenvironment of Gastroenteropancreatic Neuroendocrine Neoplasms2021
- Author(s)
  Hasegawa Sho、Kobayashi Noritoshi、Okubo Naoki、Tokuhisa Motohiko、Goto Ayumu、Kurita Yusuke、Sato Takamitsu、Hosono Kunihiro、Endo Itaru、Nakajima Atsushi、Ichikawa Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 7 Pages: 977-983
- DOI
  10.2169/internalmedicine.5648-20
- NAID
  130008014370
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08011
[Journal Article] The placement of multiple plastic stents still has important roles in candidates for chemotherapy for unresectable perihilar cholangiocarcinoma2020
- Author(s)
  Iwasaki Akito、Kubota Kensuke、Kurita Yusuke、Hasegawa Sho、Fujita Yuji、Kagawa Koji、Kato Shingo、Sekino Yusuke、Hosono Kunihiro、Nakajima Atsushi
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 27 Issue: 10 Pages: 700-711
- DOI
  10.1002/jhbp.804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08011
[Journal Article] Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial.2016
- Author(s)
  Higurashi T, Hosono K, Takahashi H, Komiya Y, Umezawa S, Sakai E, Uchiyama T, Taniguchi L, Hata Y, Uchiyama S, Hattori A, Nagase H, Kessoku T, Arimoto J, Matsuhashi N, Inayama Y, Yamanaka S, Taguri M, Nakajima A.
- Journal Title
  
  Lancet Oncol.
  
  Volume: 17 Issue: 4 Pages: 475-783
- DOI
  10.1016/s1470-2045(15)00565-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860519, KAKENHI-PROJECT-16K19357
[Journal Article] 【生活習慣と肝・胆疾患】生活習慣からみた胆管癌の危険因子2014
- Author(s)
  細野邦広, 藤田祐司, 関野雄典, 窪田賢輔, 中島淳
- Journal Title
  
  消化器内科
  
  Volume: 58 Pages: 677-681
- Data Source
  KAKENHI-PROJECT-26860519
[Journal Article] Covered self-expandable metal stent deployment promises safe neoadjuvant chemoradiation therapy in patients with borderline resectable pancreatic head cancer2014
- Author(s)
  Kubota K, Sato T, Watanabe S, Hosono K, Kobayashi N, Mori R, Taniguchi K, Matsuyama R, Endo I, Nakajima A
- Journal Title
  
  Dig Endosc.
  
  Volume: 26 Issue: 1 Pages: 77-86
- DOI
  10.1111/den.12049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Diagnosis of biliary cystadenoma by peroral video cholangioscopy.2013
- Author(s)
  Watanabe S, Sato T, Hosono K, Kobayashi N, Endo I, Nakayama T, Inayama Y, Nakajima A, Kubota K.
- Journal Title
  
  Endoscopy
  
  Volume: 45 Issue: 10 Pages: 835-837
- DOI
  10.1055/s-0033-1344330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Needle-knife precut papillotomy with a small incision over a pancreatic stent improves the success rate and reduces the complication rate in difficult biliary cannulations2013
- Author(s)
  Kubota K, Sato T, Kato S, Watanabe S, Hosono K, Kobayashi N, Hisatomi K, Matsuhashi N, Nakajima A.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 20 Issue: 3 Pages: 382-8
- DOI
  10.1007/s00534-012-0552-4
- NAID
  10031168235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Colon epithelial proliferation and carcinogenesis in diet-induced obesity2013
- Author(s)
  Takahashi H, Hosono K, Endo H, Nakajima A
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 28 Issue: S4 Pages: 41-47
- DOI
  10.1111/jgh.12240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] A novel scoring system for arterial invasion of pancreatic body and tail cancer based on multidetector row computed tomography and biomarkers2013
- Author(s)
  Watanabe S, Kobayashi N, Kubota K, Sato T, Kato S, Hosono K, Shimamura T, Inayama Y, Nakajima A, Endo I
- Journal Title
  
  Pancreatology
  
  Volume: 13 Issue: 2 Pages: 161-9
- DOI
  10.1016/j.pan.2012.12.364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Inamori MEarly Effect of Single-dose Sitagliptin Administration on Gastric Emptying : Crossover Study Using the (13)C Breath Test2013
- Author(s)
  Nonaka T, Sekino Y, Iida H, Yamada E, Ohkubo H, Sakai E, Higurashi T, Hosono K, Endo H, Koide T, Takahashi H, Fujita K, Yoneda M, Goto A, Kusakabe A, Kobayashi N, Gotoh E, Maeda S, Nakajima A, Nosaka C
- Journal Title
  
  J Neurogastroenterol Motil.
  
  Volume: 19 Issue: 2 Pages: 227-32
- DOI
  10.5056/jnm.2013.19.2.227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714, KAKENHI-PROJECT-25860505, KAKENHI-PROJECT-25860506
[Journal Article] Factors predicting the presence of small bowel lesions in patients with obscure gastrointestinal bleeding.2013
- Author(s)
  Sakai E, Endo H, Taniguchi L, Hata Y, Ezuka A, Nagase H, Yamada E, Ohkubo H, Higurashi T, Sekino Y, Koide T, Iida H, Hosono K, Nonaka T, Takahashi H, Inamori M, Maeda S, Nakajima A.
- Journal Title
  
  Dig Endosc.
  
  Volume: 25 Issue: 4 Pages: 412-420
- DOI
  10.1111/den.12002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714, KAKENHI-PROJECT-25860506
[Journal Article] aPKClambda/iota is a beneficial prognostic marker for pancreatic neoplasms.2013
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K, Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo I, Ohno S, Maeda S, Nakajima A
- Journal Title
  
  Pancreatology
  
  Volume: 13 Issue: 4 Pages: 360-8
- DOI
  10.1016/j.pan.2013.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-24790714
[Journal Article] Diagnosis of biliary cystadenoma by peroral video cholangioscopy2013
- Author(s)
  Watanabe S, Sato T, Hosono K, Kobayashi N, Endo I, Nakayama T, Inayama Y, Nakajima A, Kubota K
- Journal Title
  
  Endoscopy
  
  Volume: 45 Issue: S 02 Pages: E284-E285
- DOI
  10.1055/s-0033-1344416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Tumor diameter and Ki-67 expression in biopsy could be diagnostic markers discriminating from adenoma and early stage cancer in patients with ampullary tumors2013
- Author(s)
  Kubota K, Fujita Y, Sato T, Watanabe S, Hosono K, Yoneda M, Kirikoshi H, Hisatomi K, Matsuhashi N, Endo I, Inayama Y, Nakajima A
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 20 Issue: 5 Pages: 531-7
- DOI
  10.1007/s00534-013-0594-2
- NAID
  10031183511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790714
[Journal Article] Relationship of human rectal aberrant crypt foci and formation of colorectal polyp: One-year following up after polypectomy.2012
- Author(s)
  Hirokazu Takahashi
- Journal Title
  
  World J Gastrointest Endosc
  
  Volume: 4 Issue: 12 Pages: 561-4
- DOI
  10.4253/wjge.v4.i12.561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas.2012
- Author(s)
  Kunihiro Hosono
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 18 Issue: 38 Pages: 5360-8
- DOI
  10.3748/wjg.v18.i38.5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF): a double-blind randomized controlled trial.2012
- Author(s)
  Takuma Higurashi
- Journal Title
  
  BMC Cancer
  
  Volume: 12 Issue: 1 Pages: 413-413
- DOI
  10.1186/1471-2407-12-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Journal Article] Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.2012
- Author(s)
  Higurashi T, Takahashi H, Endo H, Hosono K, Uchiyama T, Hata Y,Ezuka A, Yamanaka S, Inayama Y,et.al.
- Journal Title
  
  BMC Cancer.
  
  Volume: 12(1) Issue: 1 Pages: 118-118
- DOI
  10.1186/1471-2407-12-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590468, KAKENHI-PROJECT-23790374, KAKENHI-PROJECT-24590948, KAKENHI-PROJECT-24790714
[Presentation] サルコペニアからみた高齢者のERCP関連偶発症の検討2020
- Author(s)
  細野邦広　佐藤高光　中島淳
- Organizer
  JDDW 2020
- Data Source
  KAKENHI-PROJECT-18K08011
[Presentation] 胆汁オルガノイドを用いた胆道癌診療の新たな展開2019
- Author(s)
  細野邦広　松浦哲也　中島淳
- Organizer
  第105回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K08011
[Presentation] New diagnostic approach for biliary tract cancer using organoid culture2019
- Author(s)
  Kunihiro Hosono, Tetsuya matuura, Atsushi Nakajima
- Organizer
  DDW 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08011

1. SASAKI Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 高橋宏和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 大野茂男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山中正二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hosono Kunihiro 細野 邦広

HOSONO Kunihiro 細野 邦広

Research Projects

Research Products

Co-Researchers

Chemoprevention of pancreatic cancer by metforminPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Increased TNF-R1 expression as a promising biomarker of human colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemopreventive effects of metformin for colon carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pathological Findings of the Host Immune Reaction in the Tumor Microenvironment of Gastroenteropancreatic Neuroendocrine Neoplasms2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The placement of multiple plastic stents still has important roles in candidates for chemotherapy for unresectable perihilar cholangiocarcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【生活習慣と肝・胆疾患】 生活習慣からみた胆管癌の危険因子2014

Author(s)

Journal Title

Data Source

[Journal Article] Covered self-expandable metal stent deployment promises safe neoadjuvant chemoradiation therapy in patients with borderline resectable pancreatic head cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnosis of biliary cystadenoma by peroral video cholangioscopy.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Needle-knife precut papillotomy with a small incision over a pancreatic stent improves the success rate and reduces the complication rate in difficult biliary cannulations2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Colon epithelial proliferation and carcinogenesis in diet-induced obesity2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel scoring system for arterial invasion of pancreatic body and tail cancer based on multidetector row computed tomography and biomarkers2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inamori MEarly Effect of Single-dose Sitagliptin Administration on Gastric Emptying : Crossover Study Using the (13)C Breath Test2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors predicting the presence of small bowel lesions in patients with obscure gastrointestinal bleeding.2013

Author(s)

Journal Title

Hosono Kunihiro 細野邦広

HOSONO Kunihiro 細野邦広

[Journal Article] 【生活習慣と肝・胆疾患】生活習慣からみた胆管癌の危険因子2014