Takashima Shigeo 高島茂雄

… Alternative Names

TAKASHIMA Shigeo 高島茂雄

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Researcher Number	50537610
Other IDs
Affiliation (Current)	2025: 岐阜大学, 糖鎖生命コア研究所, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岐阜大学, 糖鎖生命コア研究所, 准教授 2021: 岐阜大学, 糖鎖生命コア研究所, 助教 2019 – 2020: 岐阜大学, 高等研究院, 助教 2018: 岐阜大学, 研究推進・社会連携機構, 助教 2013 – 2017: 岐阜大学, 生命科学総合研究支援センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 42020:Veterinary medical science-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 極長鎖脂肪酸 / ペルオキシソーム形成異常症 / プラズマローゲン / ペルオキシソーム / ゼブラフィッシュ / PEX遺伝子 / 先天代謝異常症 / フィタン酸 / CD22 / LC-MS … More / iPS細胞 / 質量分析 / 分枝脂肪酸 / HEK293細胞 / ペルオキシソーム病 / 先天性代謝異常症 / 疾患モデル動物 … More Except Principal Investigator 極長鎖脂肪酸 / 脱髄 / iPS細胞 / ペルオキシソーム / ゼブラフィッシュ / ペルオキシソーム病 / 病型規定因子 / 副腎白質ジストロフィー / モデル生物 / ゲノム編集 / モデルフィッシュ / DBP欠損症 / マーカー / バイオマーカー / 牛伝染性リンパ腫 / エクソソーム / ERストレス / TFE3 / ATF6/CREB3ファミリー / FAM134B / CREB3L2 / CREB3 / CREB3ファミリー / 小胞体関連分解 / 小胞体ストレス / FAM143B / ATF6/CREB3 family / ERAD / CREB3 family / ゴルジ体ストレス / 神経発生異常 / 全エクソーム解析 / 診断システム / 脂肪肝 / Zellweger症候群 / モデルマウス / 造血細胞移植 / 疾患モデルマウス / 大脳型発症因子 / 神経細胞接着因子 / 二頭酵素欠損症 / マイクロアレイ解析 / 神経接着因子 / 早期診断 / 造血幹細胞移植 / エピゲノム解析 / 白質変性症 / マイクロアレイ / 疾患モデル / 副腎機能不全 / 脱随 / バイオインフォマティクス / 網羅的解析 / 脂肪酸代謝異常 / 発生異常 / 脂質代謝異常 Less

ペルオキシソーム生合成におけるCD22/Siglec-2の役割の解明Principal Investigator
- Principal Investigator
  
  高島茂雄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
ぺルオキシソーム病モデルフィッシュを用いた神経変性疾患の重症度予測と治療法の開発
- Principal Investigator
  
  久保田一生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
Studies on the interaction between changes of molecules in exosomes and the development of enzootic bovine leukosis
- Principal Investigator
  
  猪島康雄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Identification of the pathological metabolites of peroxisome biogenesis disorder using disease modelsPrincipal Investigator
- Principal Investigator
  
  Takashima Shigeo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
Analysis of novel mechanisms of aging-related diseases focusing on Golgi stress signaling
- Principal Investigator
  
  Oh-hashi Kentaro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu University
Study of disease model fish with peroxisomal biogenesis disorder for identification of pathological agent and treatment.Principal Investigator
- Principal Investigator
  
  Takashima Shigeo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Development of phenotype predictive diagnosis method and treatment in adrenoleukodystrophy by the methods combines patient resource and disease model
- Principal Investigator
  
  SHIMOZAWA Nobuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Research on elucidation of pathology and drug discovery in peroxisomal diseases using stem cells and diseased model organisms
- Principal Investigator
  
  SHIMOZAWA Nobuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Understanding the pathology of peroxisomal diseasesPrincipal Investigator
- Principal Investigator
  
  Takashima Shigeo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Clarification of the relation between the pathology of neurometabolic diseases and peroxisomal function
- Principal Investigator
  
  SHIMOZAWA Nobuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Clarification of the pathology of adrenoleukodystrophy
- Principal Investigator
  
  SHIMOZAWA Nobuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University

All 2023 2022 2021 2020 2018 2017 2015 2013 Other

All Journal Article Presentation

[Journal Article] Characterization of mRNA signature in milk small extracellular vesicles from cattle infected with bovine leukemia virus2023
- Author(s)
  Rahman Md. Matiur、Ishikawa Hinata、Yamauchi Marika、Takashima Shigeo、Kamatari Yuji O.、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Pathogens
  
  Volume: 12 Issue: 10 Pages: 1239-1239
- DOI
  10.3390/pathogens12101239
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0161, KAKENHI-PROJECT-23K21269, KAKENHI-PROJECT-23K28190
[Journal Article] Identification of Suitable Internal Control miRNAs in Bovine Milk Small Extracellular Vesicles for Normalization in Quantitative Real-Time Polymerase Chain Reaction2023
- Author(s)
  Rahman Md. Matiur、Nakanishi Ryoka、Tsukada Fumi、Takashima Shigeo、Wakihara Yoshiko、Kamatari Yuji O.、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Membranes
  
  Volume: 13 Issue: 2 Pages: 185-185
- DOI
  10.3390/membranes13020185
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-22KF0161, KAKENHI-PROJECT-23K21269, KAKENHI-PROJECT-23K28190
[Journal Article] Development of a system adapted for the diagnosis and evaluation of peroxisomal disorders by measuring bile acid intermediates.2023
- Author(s)
  Hiroki Kawai, Shigeo Takashima, Akiko Ohba, Kayoko Toyoshi, Kazuo Kubota, Hidenori Ohnishi, Nobuyuki Shimozawa
- Journal Title
  
  Brain & development
  
  Volume: 45 Pages: 58-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08254
[Journal Article] Hypomorphic mutation of PEX3 with peroxisomal mosaicism reveals the oscillating nature of peroxisome biogenesis coupled with differential metabolic activities2022
- Author(s)
  Takashima Shigeo、Fujita Haruka、Toyoshi Kayoko、Ohba Akiko、Hirata Yoko、Shimozawa Nobuyuki、Oh-hashi Kentaro
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 137 Issue: 1-2 Pages: 68-80
- DOI
  10.1016/j.ymgme.2022.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03640, KAKENHI-PROJECT-20K08254, KAKENHI-PROJECT-19H04030
[Journal Article] Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle2022
- Author(s)
  Tsukada Fumi、Takashima Shigeo、Wakihara Yoshiko、Kamatari Yuji O.、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 18 Pages: 10782-10782
- DOI
  10.3390/ijms231810782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-22KF0161, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-23K21269
[Journal Article] Identification of Potential mRNA Biomarkers in Milk Small Extracellular Vesicles of Enzootic Bovine Leukosis Cattle2022
- Author(s)
  Hiraoka Mami、Takashima Shigeo、Wakihara Yoshiko、Kamatari Yuji O.、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 5 Pages: 1022-1022
- DOI
  10.3390/v14051022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-22KF0161, KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-23K21269
[Journal Article] Comparing microRNA in milk small extracellular vesicles among healthy cattle and cattle at high risk for bovine leukemia virus transmission2022
- Author(s)
  Nakanishi Ryoka、Takashima Shigeo、Wakihara Yoshiko、Kamatari Yuji O.、Kitamura Yuko、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Journal of Dairy Science
  
  Volume: 105 Issue: 6 Pages: 5370-5380
- DOI
  10.3168/jds.2021-20989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KF0161, KAKENHI-PROJECT-23K21269
[Journal Article] Comprehensive Proteomic Analysis Revealed a Large Number of Newly Identified Proteins in the Small Extracellular Vesicles of Milk from Late-Stage Lactating Cows2021
- Author(s)
  Rahman Md. Matiur、Takashima Shigeo、Kamatari Yuji O.、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Animals
  
  Volume: 11 Issue: 9 Pages: 2506-2506
- DOI
  10.3390/ani11092506
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21269
[Journal Article] Putative Internal Control Genes in Bovine Milk Small Extracellular Vesicles Suitable for Normalization in Quantitative Real Time-Polymerase Chain Reaction2021
- Author(s)
  Rahman Md. Matiur、Takashima Shigeo、Kamatari Yuji O.、Badr Yassien、Shimizu Kaori、Okada Ayaka、Inoshima Yasuo
- Journal Title
  
  Membranes
  
  Volume: 11 Issue: 12 Pages: 933-933
- DOI
  10.3390/membranes11120933
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21269
[Journal Article] Proteomic profiling of milk small extracellular vesicles from bovine leukemia virus-infected cattle.2021
- Author(s)
  Rahman MM, Takashima S, Kamatari YO, Badr Y, Kitamura Y, Shimizu K, Okada A, Inoshima Y
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 2951-2951
- DOI
  10.1038/s41598-021-82598-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06390, KAKENHI-PROJECT-20H04285, KAKENHI-PROJECT-23K21269
[Journal Article] Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes.2021
- Author(s)
  Takashima S, Takemoto S, Toyoshi K, Ohba A, Shimozawa N.
- Journal Title
  
  Mol Genet Metab
  
  Volume: 133 Issue: 3 Pages: 307-323
- DOI
  10.1016/j.ymgme.2021.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03640, KAKENHI-PROJECT-20K08254
[Journal Article] Positional determination of the carbon?carbon double bonds in unsaturated fatty acids mediated by solvent plasmatization using LC?MS2020
- Author(s)
  Takashima Shigeo、Toyoshi Kayoko、Yamamoto Takuhei、Shimozawa Nobuyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12988-12988
- DOI
  10.1038/s41598-020-69833-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08254, KAKENHI-PROJECT-20H03640
[Journal Article] Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.2018
- Author(s)
  Hama K, Fujiwara Y, Morita M, Yamazaki F, Nakashima Y, Takei S, Takashima S, Setou M, Shimozawa N, Imanaka T, Yokoyama K.
- Journal Title
  
  Lipids
  
  Volume: 53 Issue: 1 Pages: 85-102
- DOI
  10.1002/lipd.12022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01691, KAKENHI-PROJECT-16K09961, KAKENHI-PROJECT-17K10062, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04875, KAKENHI-PROJECT-15K15389
[Journal Article] Analyses of the fatty acid separation principle using liquid chromatography-mass spectrometry2018
- Author(s)
  Takashima S, Toyoshi K, Shimozawa N
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 2 Pages: 21-33
- NAID
  130007897983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09963
[Journal Article] Ataxic form of autosomal recessive PEX10-related peroxisome biogenesis disorders with a novel compound heterozygous gene mutation and characteristic clinical phenotype.2017
- Author(s)
  Toru Yamashita, Jun Mitsui, Nobuyuki Shimozawa, Shigeo Takashima, Hiroshi Umemurad, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Takashi Matsukawa, Hiroyuki Ishiura, Jun Yoshimura, Koichiro Doi, Shinichi Morishita, Shoji Tsuji, Koji Abe.
- Journal Title
  
  J Neurological Sciences
  
  Volume: 375 Pages: 424-429
- DOI
  10.1016/j.jns.2017.02.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15389, KAKENHI-PROJECT-16K09963
[Journal Article] bHLH proneural genes as cell fate determinants of entero-endocrine cells, an evolutionarily conserved lineage sharing a common root with sensory neurons2017
- Author(s)
  Hartenstein Volker、Takashima Shigeo、Hartenstein Parvana、Asanad Samuel、Asanad Kian
- Journal Title
  
  Developmental Biology
  
  Volume: 431 Issue: 1 Pages: 36-47
- DOI
  10.1016/j.ydbio.2017.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09963
[Journal Article] A first case of adrenomyeloneuropathy with mutation Y174S of the adrenoleukodystrophy gene.2017
- Author(s)
  Horikawa Y, Enya M, Yoshikura N, Kitagawa J, Takashima S, Shimozawa N, Takeda J.
- Journal Title
  
  Neuro Endocrinol Lett.
  
  Volume: 38 Pages: 13-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15389
[Journal Article] Effect of Lorenzo's Oil on Hepatic Gene Expression and the Serum Fatty Acid Level in abcd1-Deficient Mice.2017
- Author(s)
  Morita M, Honda A, Kobayashi A, Watanabe Y, Watanabe S, Kawaguchi K, Takashima S, Shimozawa N, Imanaka T.
- Journal Title
  
  JIMD Rep.
  
  Volume: 38 Pages: 67-74
- DOI
  10.1007/8904_2017_32
- ISBN
  9783662566091, 9783662566107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09961, KAKENHI-PROJECT-16K09963, KAKENHI-PROJECT-15H04875, KAKENHI-PROJECT-15K15389
[Journal Article] Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry.2017
- Author(s)
  Shigeo Takashima, Kayoko Toyoshi, Takahiro Itoh, Naomi Kajiwara, Ayako Honda, Akiko Ohba, Shoko Takemoto, Satoshi Yoshida, Nobuyuki Shimozawa.
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 120 Issue: 3 Pages: 255-268
- DOI
  10.1016/j.ymgme.2016.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04875, KAKENHI-PROJECT-16K09963, KAKENHI-PROJECT-15K15389
[Journal Article] A first case of adrenomyeloneuropathy with mutation Y174S of the adrenoleukodystrophy gene2017
- Author(s)
  Horikawa Y, Enya M, Yoshikura N, Kitagawa J, Takashima S, Shimozawa N, Takeda J.
- Journal Title
  
  Neuro Endocrinol Lett
  
  Volume: 38 Pages: 13-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04875
[Presentation] Identification of suitable internal control mRNAs and miRNAs in bovine milk small extracellular vesicles for normalization in quantitative real-time polymerase chain reaction2023
- Author(s)
  Md. Matiur Rahman, Ryoka Nakanishi, Fumi Tsukada, Shigeo Takashima, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
- Organizer
  International Society for Extracellular Vesicles 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] モザイク様ペルオキシソームを生じるPEX3変異細胞ではペルオキシソームの周期的な生合成が起こっている2022
- Author(s)
  高島茂雄, 藤田遥, 豊吉佳代子, 大場亜希子, 平田洋子, 下澤伸行, 大橋憲太郎
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08254
[Presentation] 軽症型ペルオキシソーム病モデル細胞が示すペルオキシソーム生合成の周期的変化と代謝変動2022
- Author(s)
  高島茂雄, 藤田遥, 豊吉佳代子, 大場亜希子, 平田洋子, 下澤伸行, 大橋憲太郎
- Organizer
  第63回日本先天代謝異常学会学術集会, 第18回アジア先天代謝異常症シンポジウム
- Data Source
  KAKENHI-PROJECT-20K08254
[Presentation] Development of a monitoring method for high risk cattle of bovine leukemia virus transmission and onset of enzootic bovine leukosis using milk exosomes2022
- Author(s)
  Md. Matiur Rahman, Shigeo Takashima, Yuji O. Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
- Organizer
  第29回アジア獣医師会連合(FAVA)大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] mRNA dynamics in milk extracellular vesicles in correlation with bovine leukemia virus copy number in cattle2021
- Author(s)
  Md. Matiur Rahman, Shigeo Takashima, Yuji O. Kamatari, Yuko Kitamura, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima
- Organizer
  第8回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] ゼブラフィッシュZellweger syndromeモデルにおける遺伝子発現変動解析2021
- Author(s)
  高島茂雄, 豊吉佳代子, 大場亜希子, 下澤伸行
- Organizer
  第６２回日本先天代謝異常学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08254
[Presentation] 生乳エクソソーム内包miRNAの網羅的解析による地方病性牛伝染性リンパ腫の発症バイオマーカーの探索2021
- Author(s)
  塚田文、脇原祥子、高島茂雄、葛岡功弥子、岡田彩加、猪島康雄
- Organizer
  第8回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] LC-MSを用いた不飽和脂肪酸の二重結合位置の同定2021
- Author(s)
  高島茂雄, 豊吉佳代子, 大場亜希子, 下澤伸行
- Organizer
  第６０回日本油化学会年会
- Data Source
  KAKENHI-PROJECT-20K08254
[Presentation] 地方病性牛伝染性リンパ腫発症牛における生乳エクソソーム内包mRNAの網羅的解析による発症バイオマーカーの探索2021
- Author(s)
  平岡真実，脇原祥子，高島茂雄，葛岡功弥子，岡田彩加，猪島康雄
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] 地方病性牛伝染性リンパ腫発症を反映する生乳エクソソーム内包miRNAバイオマーカーの探索2021
- Author(s)
  塚田文, 脇原祥子, 高島茂雄, 葛岡功弥子, 岡田彩加, 猪島康雄
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] mRNA biomarkers in milk extracellular vesicles2021
- Author(s)
  Md. Matiur Rahman, 高島茂雄, 鎌足雄司, Badr Yassien, 北村夕子, 清水薫, 岡田彩加, 猪島康雄
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] 地方病性牛伝染性リンパ腫発症牛の生乳エクソソーム内包mRNA解析と発症バイオマーカーの探索2021
- Author(s)
  平岡真実, 脇原祥子, 高島茂雄, 葛岡功弥子, 岡田彩加, 猪島康雄
- Organizer
  令和3年度獣医学術中部地区学会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] 生乳エクソソームを用いた地方病性牛伝染性リンパ腫発症リスクを反映するmiRNAバイオマーカーの探索2021
- Author(s)
  塚田文, 脇原祥子, 高島茂雄, 葛岡功弥子, 岡田彩加, 猪島康雄
- Organizer
  令和3年度獣医学術中部地区学会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] 地方病性牛伝染性リンパ腫発症牛の生乳エクソソームにおけるmRNAの網羅的解析と発症バイオマーカーの探索および有用性の検証2021
- Author(s)
  平岡真実、脇原祥子、高島茂雄、葛岡功弥子、岡田彩加、猪島康雄
- Organizer
  第8回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-23K21269
[Presentation] ゼブラフィッシュモデルを使ったZellweger syndrome病態発症機構の探索2021
- Author(s)
  高島茂雄, 豊吉佳代子, 大場亜希子, 下澤伸行
- Organizer
  第６２回日本先天代謝異常学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08254
[Presentation] Pathological study of Zellweger syndrome using disease model fish2018
- Author(s)
  Shigeo Takashima, Shoko Takemoto, Kayoko Toyoshi, Akiko Ohba, Nobuyuki Shimozawa
- Organizer
  第60回日本先天代謝異常学会総会/第16回アジア先天代謝異常症シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] ゲノム編集により作製したPEX3変異細胞を用いたペルオキシソーム形成異常症の病態解明と治療法に関する研究2018
- Author(s)
  藤田遥, 高島茂雄, 下澤伸行, 平田洋子, 大橋憲太郎
- Organizer
  日本生化学会中部支部第82回例会
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] PEX3変異細胞を用いたペルオキシソーム形成異常症発症因子の探索2018
- Author(s)
  藤田遥, 大橋憲太郎, 平田洋子, 下澤伸行, 高島茂雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] Therapeutic effect by bezafibrate, using fibroblasts from patients with peroxisomal diseases2018
- Author(s)
  Hiroki Kawai, Shigeo Takashima, Toshiyuki Fukao and Nobuyuki Shimozawa
- Organizer
  第60回日本先天代謝異常学会総会/第16回アジア先天代謝異常症シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] Pathological study of Zellweger syndrome using disease model fish2018
- Author(s)
  Shigeo Takashima, Shoko Takemoto, Kayoko Toyoshi, Akiko Ohba, Nobuyuki Shimozawa
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] Study of the molecular pathology of the human peroxisome biogenesis disorder using zebrafish2017
- Author(s)
  Shoko Takemoto, Kayoko Toyoshi, Akiko Ohba, Haruka Fujita, Nobuyuki Shimozawa, Shigeo Takashima
- Organizer
  第50回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] 質量分析を応用したペルオキシソーム病代謝解析法の開発2017
- Author(s)
  高島茂雄
- Organizer
  第42回日本医用マススペクトル学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] Establishment and Phenotypic Analysis of the Disease Model Fish for Peroxisomal Biogenesis Disorder2017
- Author(s)
  Shigeo Takashima, Shoko Takemoto, Kayoko Toyoshi, Akiko Ohba, Haruka Fujita, Kentaro Oh-hashi, Yoko Morita, Nobuyuki Shimozawa
- Organizer
  第59回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K09963
[Presentation] ペルオキシソーム形成異常症モデルゼブラフィッシュの表現型解析2015
- Author(s)
  高島茂雄, 豊吉佳代子, 本田綾子, 大場亜希子, 下澤伸行
- Organizer
  第57回日本先天代謝異常学会総会・第13回アジア先天代謝異常症シンポジウム
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25860855
[Presentation] LC／MSを用いたペルオキシソーム病関連因子の解析2015
- Author(s)
  高島茂雄, 伊藤貴洋, 吉田敏, 下澤伸行
- Organizer
  第57回日本先天代謝異常学会総会・第13回アジア先天代謝異常症シンポジウム
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25860855
[Presentation] Zebrafish as a model system to understand the pathology of peroxisomal diseases2013
- Author(s)
  Shigeo Takashima, Kayoko Toyoshi, Nobuyuki Shimozawa
- Organizer
  The 3rd Asian Congress for Inherited Metabolic Diseases (ACIMD)/The 55th Annual Meeting of The Japanese Society for Inherited Metabolic Diseases (JSIMD)
- Place of Presentation
  Tokyo Bay Maihama Hotel Club Resort, Chiba, Japan
- Data Source
  KAKENHI-PROJECT-25860855
[Presentation] Analysis of phathology of peroxisomal biogenesis disorder
- Author(s)
  Shigeo Takashima, Kayoko Toyoshi, Takahiro Ito, Naomi Kajiwara, Akiko Ohba, Ayako Honda, Satoshi Yoshida, Nobuyuki Shimozawa
- Organizer
  第56回日本先天代謝異常学会, The 12th Annual Symposium of the Asian Society for Inherited Metabolic Diseases
- Place of Presentation
  Koyo Grand Hotel, Sendai, Japan
- Year and Date
  2014-11-13 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-25860855

1. SHIMOZAWA Nobuyuki (00240797)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. Oh-hashi Kentaro (50332953)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 石垣診祐 (40378170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 天谷文昌 (60347466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 内尾こずえ (70373397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 猪島康雄 (20355184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. 岡田彩加 (70784221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 松橋珠子 (60504355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 久保田一生 (10526940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAMA Kotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 鎌足雄司

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
12. 守田雅志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. RAHMAN MD. MATIUR

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takashima Shigeo 高島 茂雄

TAKASHIMA Shigeo 高島 茂雄

Research Projects

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Co-Researchers

ペルオキシソーム生合成におけるCD22/Siglec-2の役割の解明Principal Investigator

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ぺルオキシソーム病モデルフィッシュを用いた神経変性疾患の重症度予測と治療法の開発

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Studies on the interaction between changes of molecules in exosomes and the development of enzootic bovine leukosis

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Identification of the pathological metabolites of peroxisome biogenesis disorder using disease modelsPrincipal Investigator

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Analysis of novel mechanisms of aging-related diseases focusing on Golgi stress signaling

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Study of disease model fish with peroxisomal biogenesis disorder for identification of pathological agent and treatment.Principal Investigator

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Development of phenotype predictive diagnosis method and treatment in adrenoleukodystrophy by the methods combines patient resource and disease model

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Research on elucidation of pathology and drug discovery in peroxisomal diseases using stem cells and diseased model organisms

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Understanding the pathology of peroxisomal diseasesPrincipal Investigator

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Clarification of the relation between the pathology of neurometabolic diseases and peroxisomal function

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Clarification of the pathology of adrenoleukodystrophy

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[Journal Article] Characterization of mRNA signature in milk small extracellular vesicles from cattle infected with bovine leukemia virus2023

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[Journal Article] Identification of Suitable Internal Control miRNAs in Bovine Milk Small Extracellular Vesicles for Normalization in Quantitative Real-Time Polymerase Chain Reaction2023

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DOI

Takashima Shigeo 高島茂雄

TAKASHIMA Shigeo 高島茂雄