Takami Hirokazu 高見浩数

Researcher Number	50548625
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 講師 2020 – 2024: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 中枢神経 / 胚細胞腫 / 発現解析 / 腫瘍マーカー / コピー数異常 / メチル化解析 / RNAシークエンス / 空間トランスクリプトーム / ロングリードシークエンス / ゲノム構造異常 / 腫瘍免疫 / 予後 … More Except Principal Investigator … More ゲノム解析 / JCCG / 中枢神経系胚細胞腫 / グリオーマ / 小児脳腫瘍 / 血管芽腫 / 腫瘍血管新生 / エピゲノム解析 / 多層オミクス解析 / 頭蓋底脊索腫 / 神経膠腫 / カルパイン阻害薬 / Calpain-1 / HMRG / 蛍光プローブ / バイオマーカー / ユビキタス検査 / 感染症 / がん / 未病 / 網羅的発現解析 / DNAメチル化 / 中枢神経系腫瘍 / 人体病理 Less

Integrated genomic pathological and clinical analysis of pediatric brain tumors using the Japan Childrens Cancer Group cohort
- Principal Investigator
  
  市村幸一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyorin University
微量検体のユビキタス自動分析装置開発と、未病とバイオマーカーの相関解明
- Principal Investigator
  
  笠間敏博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
  Basic Section 90140:Medical technology assessment-related
  Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
- Research Institution
  The University of Tokyo
中枢神経胚細胞腫の治療抵抗性克服に向けた腫瘍内不均一性と起源細胞・腫瘍免疫の解明Principal Investigator
- Principal Investigator
  
  高見浩数
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Novel fluorescent labeling system for brain tumor surgery and its therapeutic application
- Principal Investigator
  
  田中將太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Okayama University
  The University of Tokyo
ゲノム・エピゲノム解析に基づく多層オミクス解析による頭蓋底脊索腫の悪性度分類
- Principal Investigator
  
  長谷川洋敬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Elucidation of tumor angiogenesis mechanisms other than HIF pathway and search for novel anti-angiogenic drugs
- Principal Investigator
  
  高柳俊作
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
The novel classification system of pediatric brain tumors using machine learning technology
- Principal Investigator
  
  里見介史
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyorin University
中枢神経悪性胚細胞腫に対する標的治療に向けた、ゲノム構造異常・変異の解明Principal Investigator
- Principal Investigator
  
  高見浩数
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
Analysis on tumor-immune interaction landscape in CNS germ cell tumorsPrincipal Investigator
- Principal Investigator
  
  Takami Hirokazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 遺伝統計学の新潮流 ─新規創薬・個別化医療への挑戦2024
- Author(s)
  高見浩数
- Total Pages
  240
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22K16650
[Book] 臨床脳腫瘍学─最新の診断・治療と病態─2023
- Author(s)
  高見浩数
- Total Pages
  705
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-22K16650
[Book] 脳腫瘍に対する標準治療と薬物療法2023
- Author(s)
  高見浩数
- Publisher
  自然科学社
- ISBN
  9784909260697
- Data Source
  KAKENHI-PROJECT-22K16650
[Journal Article] Successful Multimodal Treatment of Intracranial Growing Teratoma Syndrome with Malignant Features.2024
- Author(s)
  Satake D, Natsumeda M, Satomi K, Tada M, Sato T, Okubo N, Kawabe K, Takahashi H, Tsukamoto Y, Okada M, Sano M, Iwabuchi H, Shibata N, Imamura M, Imai C, Takami H, Ichimura K, Nishikawa R, Umezu H, Kakita A, Oishi M.
- Journal Title
  
  Current Oncology
  
  Volume: 31 Issue: 4 Pages: 1831-1838
- DOI
  10.3390/curroncol31040138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-23K24297
[Journal Article] Distinct patterns of copy number alterations may predict poor outcome in central nervous system germ cell tumors2023
- Author(s)
  Takami Hirokazu、Satomi Kaishi、Fukuoka Kohei、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 15760-15760
- DOI
  10.1038/s41598-023-42842-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16650, KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-22K09272, KAKENHI-PROJECT-21K09166, KAKENHI-PROJECT-21H03047, KAKENHI-PROJECT-23K24096
[Journal Article] Impact of tumor markers on diagnosis, treatment and prognosis in CNS germ cell tumors: correlations with clinical practice and histopathology2023
- Author(s)
  Takami Hirokazu、Graffeo Christopher S.、Perry Avital、Giannini Caterina、Nakazato Yoichi、Saito Nobuhito、Matsutani Masao、Nishikawa Ryo、Daniels David J.、Ichimura Koichi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 2 Pages: 124-132
- DOI
  10.1007/s10014-023-00460-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16650, KAKENHI-PROJECT-23K24096
[Journal Article] Advances in Molecular Profiling and Developing Clinical Trials of CNS Germ Cell Tumors: Present and Future Directions2022
- Author(s)
  Takami Hirokazu
- Journal Title
  
  Current Oncology Reports
  
  Volume: 24 Issue: 1 Pages: 105-112
- DOI
  10.1007/s11912-022-01195-2
- Data Source
  KAKENHI-PROJECT-20K17918
[Journal Article] Biomarkers for risk-based treatment modifications for CNS germ cell tumors: Updates on biological underpinnings, clinical trials, and future directions2022
- Author(s)
  Takami Hirokazu、Ichimura Koichi
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12
- DOI
  10.3389/fonc.2022.982608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16650
[Journal Article] Still divergent but on the way to convergence: clinical practice of CNS germ cell tumors in Europe and North America from the perspectives of the East2022
- Author(s)
  Takami Hirokazu、Nakamura Hideo、Ichimura Koichi、Nishikawa Ryo
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: 4 Issue: 1
- DOI
  10.1093/noajnl/vdac061
- Data Source
  KAKENHI-PROJECT-20K17918
[Journal Article] Transcriptome and Methylome Analysis of CNS Germ Cell Tumor Finds its Cell-of-Origin in Embryogenesis and Reveals Shared Similarities with Testicular Counterparts.2022
- Author(s)
  Takami H, Elzawahry A, Mamatjan Y, Nishikawa R, Matsutani M, Ichimura K, et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: ePub Issue: 8 Pages: 1246-1258
- DOI
  10.1093/neuonc/noac021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03440, KAKENHI-PROJECT-21K09166, KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-22K09272, KAKENHI-PROJECT-21H03047, KAKENHI-PROJECT-20K17918
[Journal Article] Roles of Tumor Markers in Central Nervous System Germ Cell Tumors Revisited with Histopathology-Proven Cases in a Large International Cohort2022
- Author(s)
  Takami Hirokazu、Graffeo Christopher S.、Perry Avital、Giannini Caterina、Nakazato Yoichi、Saito Nobuhito、Matsutani Masao、Nishikawa Ryo、Ichimura Koichi、Daniels David J.
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 4 Pages: 979-979
- DOI
  10.3390/cancers14040979
- Data Source
  KAKENHI-PROJECT-20K17918
[Journal Article] 12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors.2021
- Author(s)
  Satomi K, Takami H, Fukushima S, Matsutani M, Nishikawa R, Ichimura K, et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: epub Issue: 5 Pages: 834-846
- DOI
  10.1093/neuonc/noab246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03440, KAKENHI-PROJECT-20K17918, KAKENHI-PROJECT-21K09166, KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-21H03047
[Journal Article] Low tumor cell content predicts favorable prognosis in germinoma patients.2021
- Author(s)
  Takami H, Satomi K, Fukuoka K, Nishikawa R, Matsutani M, Ichimura K, et al.
- Journal Title
  
  Neuro-Oncology Advanced
  
  Volume: 3 Issue: 1
- DOI
  10.1093/noajnl/vdab110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03440, KAKENHI-PROJECT-21H03047, KAKENHI-PROJECT-21K09166, KAKENHI-PROJECT-20K17918
[Presentation] 当施設における中枢神経系血管芽腫の集学的治療と今後の展望2023
- Author(s)
  高柳俊作、高見　浩数、田中將太、庄野　直之、金　太一、梅川　元之、長谷川　洋敬、小泉　聡、齊藤　延人
- Organizer
  第28回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-23K08559
[Presentation] Pathogenesis of central nervous system germ cell tumors elucidated by transcriptome and methylome analyses2023
- Author(s)
  Hirokazu Takami
- Organizer
  International Conference on Brain Tumor Research and Therapy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] IDH野生型低悪性度星細胞腫症例の臨床・病理学的特徴と治療の変遷 -46症例の解析- .2023
- Author(s)
  高柳　俊作　田中　將太高見　浩数池村　雅子齊藤　延人.
- Organizer
  第41回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-23K08559
[Presentation] 中枢神経系血管芽腫におけるVHL遺伝子異常の臨床的意義-手術成績における検討と新規分子標的薬belzutifanの適応拡大の可能性-2023
- Author(s)
  高柳　俊作、南部　翔平　高見　浩数、田中　將太、齊藤　延人
- Organizer
  第41回日本脳腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K08559
[Presentation] 中枢神経胚細胞腫におけるコピー数異常と予後との相関2023
- Author(s)
  高見浩数
- Organizer
  脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] 初発の頭蓋内原発胚細胞腫に対する多施設共同前向き臨床試験の長期フォローアップ研究2022
- Author(s)
  高見浩数
- Organizer
  脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] 中枢神経胚細胞腫における腫瘍マーカーの役割と限界2022
- Author(s)
  高見浩数
- Organizer
  脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] Prognostic Factors of CNS Germinomas; Histopathological Analyses on 114 Cases from the iGCT Consortium2022
- Author(s)
  Hirokazu Takami
- Organizer
  World Federation of Neuro Oncology Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 12p gainは中枢神経系胚細胞腫瘍の予後不良群を同定する2022
- Author(s)
  里見　介史、高見　浩数、福島　慎太郎ら
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06951
[Presentation] 中枢神経胚細胞腫のomics解析による起源細胞の同定と病態の解明2022
- Author(s)
  高見浩数
- Organizer
  第81回脳神経外科学術総会
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors2022
- Author(s)
  Kaishi Satomi, Hirokazu Takami, Shintaro Fukushima et al.
- Organizer
  World Federation of Neuro-Oncology Societies (WFNOS) 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06951
[Presentation] Biology of CNS germ cell tumors: pathological and multi-omics perspectives2022
- Author(s)
  Hirokazu Takami
- Organizer
  Society of Neuro-Oncology Latin America
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 中枢神経胚細胞腫のomics解析による起源細胞の同定と病態の解明2022
- Author(s)
  高見浩数
- Organizer
  脳神経外科学術総会
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] Transcriptome and methylome profiles of CNS germ cell tumors and their comparison with testicular counterpart2022
- Author(s)
  Hirokazu Takami
- Organizer
  Iinternational Society of Pediatric Neuro-Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 胚細胞腫の診断・治療における課題2022
- Author(s)
  高見浩数
- Organizer
  脳神経外科コングレス
- Invited
- Data Source
  KAKENHI-PROJECT-22K16650
[Presentation] Prognostic Factors of CNS Germ Cell Tumors; Molecular and Histopathological Analyses on 154 Cases from the iGCT Consortium2021
- Author(s)
  Hirokazu Takami
- Organizer
  Society of Neuro-Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 中枢神経胚細胞腫の予後を決める病理・分子マーカー2021
- Author(s)
  高見浩数
- Organizer
  日本脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-20K17918
[Presentation] 中枢神経胚細胞腫の予後因子の解明：154症例における分子病理解析2021
- Author(s)
  高見浩数
- Organizer
  日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K17918

1. 田中將太 (80643725)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. 高柳俊作 (90406489)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. 里見介史 (10633977)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 義岡孝子 (50381182)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 鈴木穣 (40323646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 笠間敏博 (00564717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 篠原満利恵 (00789133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 北川陽介 (50885150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石田穣治 (90771949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大谷理浩 (60902989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 長谷川洋敬 (60733897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 市村幸一 (40231146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 加藤元博 (40708690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 荒川芳輝 (20378649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 齋藤竜太 (10400243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 柴原純二 (60334380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤実穂 (00870859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 隈部俊宏 (10250747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山崎夏維 (30746954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 福岡講平 (60746717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 富山新太 (40385810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小森隆司 (90205526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takami Hirokazu 高見 浩数

Research Projects

Research Products

Co-Researchers

Integrated genomic pathological and clinical analysis of pediatric brain tumors using the Japan Childrens Cancer Group cohort

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

微量検体のユビキタス自動分析装置開発と、未病とバイオマーカーの相関解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

中枢神経胚細胞腫の治療抵抗性克服に向けた腫瘍内不均一性と起源細胞・腫瘍免疫の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel fluorescent labeling system for brain tumor surgery and its therapeutic application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム・エピゲノム解析に基づく多層オミクス解析による頭蓋底脊索腫の悪性度分類

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of tumor angiogenesis mechanisms other than HIF pathway and search for novel anti-angiogenic drugs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The novel classification system of pediatric brain tumors using machine learning technology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

中枢神経悪性胚細胞腫に対する標的治療に向けた、ゲノム構造異常・変異の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis on tumor-immune interaction landscape in CNS germ cell tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 遺伝統計学の新潮流 ─新規創薬・個別化医療への挑戦2024

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床脳腫瘍学─最新の診断・治療と病態─2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 脳腫瘍に対する標準治療と薬物療法2023

Author(s)

Publisher

ISBN

Data Source

[Journal Article] Successful Multimodal Treatment of Intracranial Growing Teratoma Syndrome with Malignant Features.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct patterns of copy number alterations may predict poor outcome in central nervous system germ cell tumors2023

Author(s)

Takami Hirokazu 高見浩数

[Presentation] 初発の頭蓋内原発胚細胞腫に対する多施設共同前向き臨床試験の長期フォローアップ研究2022