AKAZAWA Satoru 赤澤諭

… Alternative Names

赤澤諭アカザワサトル

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Researcher Number	50549409
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2021 – 2023: 長崎大学, 原爆後障害医療研究所, 助教 2015: 長崎大学, 保健・医療推進センター, 助教 2014: 長崎大学, 病院(医学系), 助教 2013: 長崎大学, 大学病院, 助教 … More 2012: 長崎大学, 医歯(薬)学総合研究科, 研究協力員 2012: 長崎大学, 大学病院, 研究協力員 2012: 長崎大学, 大学院・医歯薬学総合研究科, 研究協力員 2011: 長崎大学, 大学病院, 医員 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Keywords	Principal Investigator 1型糖尿病 / 自己免疫 / T細胞 / １型糖尿病 / 抗原特異的T細胞 / 樹状細胞 / IRF4 / 国際情報交流 / IRF Except Principal Investigator IRF4 … More / NODマウス / 1型糖尿病 / T細胞代謝 / 自己免疫疾患 / 膵島自己抗原 / １型糖尿病 / 膵島自己免疫 / T細胞 / Th1細胞 / Th17細胞 / IRF-4 / 樹状細胞 / グランザイムＢ / サイトカイン / Ｔ細胞 Less

1型糖尿病のエフェクター機能を反映した抗原特異的T細胞マーカーの開発Principal Investigator
- Principal Investigator
  
  赤澤諭
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nagasaki University
Exploring the relationship between changes in cellular metabolism within the pancreatic islet environment and the progression of autoimmune diabetes
- Principal Investigator
  
  Niri Tetsuro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nagasaki University
Pioneer fctor-IRF4/8-を標的にした1型糖尿病新規治療開発Principal Investigator
- Principal Investigator
  
  赤澤諭
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Nagasaki University
Development of effector cell-targeted treatment for the inhibition of type 1 diabetes
- Principal Investigator
  
  ABIRU Noriio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagasaki University
Development of new therapy for type 1 diabetes targeting for IRF-4 (interferon regulatory factor-4)Principal Investigator
- Principal Investigator
  
  AKAZAWA Satoru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Nagasaki University

All 2023 2022 2021 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Haploinsufficiency of interferon regulatory factor 4 strongly protects against autoimmune diabetes in non-obese diabetic mice.2015
- Author(s)
  Akazawa S, Kobayashi K, Kuriya G, Horie I, Yu L, Yamasaki H, Okita M, Nagayama Y, Matsuyama T, Akbari M, Yui K, Kawakami A, Abiru N.
- Journal Title
  
  Diabetologia
  
  Volume: 58 (11) Issue: 11 Pages: 2606-2614
- DOI
  10.1007/s00125-015-3724-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09437, KAKENHI-PROJECT-15H05277, KAKENHI-PROJECT-15K19518, KAKENHI-PROJECT-25293101
[Journal Article] Sequential elevation of autoantibodies to thyroglobulin and glutamic acid decarboxylase in type 1 diabetes.2013
- Author(s)
  Kawasaki E, Yasui J, Tsurumaru M, Takashima H, Ikeoka T, Mori F, Akazawa S, Ueki I, Kobayashi M, Kuwahara H, Abiru N, Yamasaki H, Kawakami A.
- Journal Title
  
  World J Diabetes
  
  Volume: 4 Issue: 5 Pages: 227-230
- DOI
  10.4239/wjd.v4.i5.227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591310, KAKENHI-PROJECT-24591334
[Journal Article] Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice.2013
- Author(s)
  Kobayashi M, Kaneko-Koike C, Abiru N, Uchida T, Akazawa S, Nakamura K, Kuriya G, Satoh T, Ida H, Kawasaki E, Yamasaki H, Nagayama Y, Sasaki H, Kawakami A
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 173(3) Issue: 3 Pages: 411-418
- DOI
  10.1111/cei.12134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591334
[Journal Article] Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.2013
- Author(s)
  Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N.
- Journal Title
  
  Diabetologia
  
  Volume: 56 Issue: 8 Pages: 1773-1780
- DOI
  10.1007/s00125-013-2935-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791060, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591334
[Presentation] Pleiotropic roles of transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2023
- Author(s)
  Tetsuro Niri, Sin-Ichi Inoue, Shinpei Nishikido, Satoru Akazawa, Masaki Miwa, Masakazu Kobayashi, Norio Abiru
- Organizer
  19th Immunology of Diabetes Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] NODマウスにおける転写因子IRF4の獲得免疫系と自然免疫系細胞への多面的関与による自己免疫性糖尿病の進展制御について2023
- Author(s)
  二里哲朗, 井上信一, 錦戸慎平, 赤澤諭, 三輪昌輝, 古林正和, 川上純, 阿比留教生
- Organizer
  第36回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] Pleiotropic roles of transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2023
- Author(s)
  Tetsuro Niri, Shin-Ichi Inoue, Shinpei Nishikido, Satoru Akazawa, Masaki Miwa, Masakazu Kobayashi, Norio Abiru
- Organizer
  19th Immunology of Diabetes Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] 転写因子IRF4の抗原特異的CD4+T細胞および自然免疫系細胞への関与と自己免疫性糖尿病進展への役割について2022
- Author(s)
  二里哲朗, 井上信一, 錦戸慎平, 赤澤諭, 三輪昌輝, 古林正和, 由井克之, 阿比留教生, 川上純
- Organizer
  第19回 1型糖尿病研究会
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] 転写因子IRF4の抗原特異的CD4+T細胞と自然免疫系細胞を介した糖尿病進展に与える影響の検討2022
- Author(s)
  二里哲朗, 井上信一, 錦戸慎平, 赤澤諭, 三輪昌輝, 古林正和, 由井克之, 川上純, 阿比留教生
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] Role of the transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2021
- Author(s)
  Tetsuro Niri, Shinpei Nishikido, Satoru Akazawa, Masaki Miwa, Masakazu Kobayashi, Norio Abiru
- Organizer
  18th Immunology of Diabetes Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] IRF4の抗原特異的CD4+T細胞および自然免疫系細胞を介した1型糖尿病における免疫制御機構の解析2021
- Author(s)
  二里哲朗, 錦戸慎, 赤澤諭, 三輪昌輝, 古林正和, 阿比留教生
- Organizer
  第20回日本先進糖尿病治療研究会・第18回1型糖尿病研究会
- Data Source
  KAKENHI-PROJECT-21K08558
[Presentation] IRF4欠損NODマウスにおける自己免疫性糖尿病の高度抑制2015
- Author(s)
  赤澤諭
- Organizer
  第13回1型糖尿病研究会
- Place of Presentation
  TKPガーデンシティPREMIUM神保町[東京都千代田区]
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15K19518
[Presentation] IL-17/IFN-γ受容体ダブル欠損NODマウスでは、離乳期以降のリンパ組織の量的増加が欠失している2015
- Author(s)
  赤澤諭
- Organizer
  第58回日本糖尿病学会　年次学術集会
- Place of Presentation
  ぱんぱしふぃっく[山口県下関市]
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K19518
[Presentation] ＩL-17/IFN-g受容体遺伝子ダブル欠損NODマウスにおける糖尿病発症抑制の相乗効果2013
- Author(s)
  阿比留教生, 厨源平, 内田隆寛, 赤澤諭, 古林正和, 川崎英二, 川上純
- Organizer
  日本糖尿病肥満動物学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] IRF4遺伝子欠損マウスにおける自己免疫性糖尿病の完全抑制2013
- Author(s)
  赤澤　諭, 阿比留教生, 古林正和, 厨　源平, 川﨑英二, 山崎浩則, 川上　純
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市国際交流会館
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] Interferon regulatory factor-4（IRF-4）欠損NODマウスにおける糖尿病の完全抑制2013
- Author(s)
  赤澤諭、阿比留教生、古林正和、厨源平、川崎英二、川上純
- Organizer
  日本糖尿病肥満動物学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] IRF4欠損NODマウスにおける糖尿病の完全抑制2013
- Author(s)
  赤澤諭, 阿比留教生, 古林正和
- Organizer
  第27回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  東京都千代田区
- Year and Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-23791036
[Presentation] Haploinsufficiency of Interferon regulatory factor 4 strongly protects from autoimmune diabetes in the non-obese diabetic mice2013
- Author(s)
  Akazawa S, Kobayashi M, Kawasaki E, Nagayama Y, Yui K, Matsuyama T, Kawakami A, Abiru N
- Organizer
  Immunology of Diabetes Society 13th International Congress
- Place of Presentation
  Lone,Australia
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] nterferon regulatory factor 4 silencing suppresses autoimmunity in the nonobese diabetic mice2012
- Author(s)
  Akazawa S, Abiru N, Uchida T, Nakamura K, Kuriya G, Satoh T, Kobayashi M, Kawasaki E, Yui K, Nagayama Y, Kawakami A
- Organizer
  International Conference of the Immunology of Diabetes
- Place of Presentation
  Victoria Canada
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] Interferon regulatory factor 4 silencing suppresses type 1 diabetes in the non-obese diabetic mice2012
- Author(s)
  Satoru Akazawa
- Organizer
  12th International Conference on the Immunology of Diabetes
- Place of Presentation
  Victoria, Canada
- Data Source
  KAKENHI-PROJECT-23791036
[Presentation] IL-17/IFN- receptor double-knockout significantly suppresses the development of diabetes compared to the IL-17 single-knockout in the NOD mouse2012
- Author(s)
  Kuriya G, Uchida T, Abiru N, Akazawa S, Kobayashi M, Nakamura K, Kawasaki E, Yamasaki H, Nagayama Y, Kanagawa O, Iwakura Y, Kawakami A
- Organizer
  International Conference of the Immunology of Diabetes
- Place of Presentation
  Victoria Canada
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] Interferon regulatory factor 4 silencing suppresses type 1 diabetes in the non-obese diabetic mice2012
- Author(s)
  Satoru Akazawa, Norio Abiru, Genpi Kuriya, Tsuyoshi Satoh, Masakazu Kobayashi
- Organizer
  12^th International Conference on the Immunology of Diabetes
- Place of Presentation
  Victoria, Canada
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PROJECT-23791036
[Presentation] IRF-4欠損NODマウスにおけるT細胞依存性膵島炎および糖尿病の抑制2012
- Author(s)
  赤澤諭, 阿比留教生, 古林正和, 厨源平
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23791036
[Presentation] IRF4遺伝子欠損NODマウスにおける膵島炎および糖尿病の完全抑制2011
- Author(s)
  赤澤諭、阿比留教生、古林正和、厨源平、中村寛、桑原宏永、内田隆寛、川崎英二、山崎浩則、川上純
- Organizer
  第9回　1型糖尿病研究会
- Place of Presentation
  大磯プリンスホテル(神奈川県)
- Data Source
  KAKENHI-PROJECT-23791036
[Presentation] IL-17/IFNγ受容体ダブル欠損ＮＯＤマウスにおけるリンパ球phenotype解析
- Author(s)
  赤澤諭，古林正和，山崎浩則，川上純，阿比留教生
- Organizer
  日本糖尿病・肥満動物学会　年次学術集会
- Place of Presentation
  芝蘭会館（京都）
- Year and Date
  2015-02-13 – 2015-02-14
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] L-17/IFN- receptor double-deficiency lacks systemic expansion of lymphocytes after weaning period which might be associated with disease susceptibility in the NOD mice
- Author(s)
  Akazawa S, Abiru N, Kobayashi M, Kawakami Ａ
- Organizer
  Immunology of Diabetes Society 14th International Congress
- Place of Presentation
  ヒルトンミュンヘンパーク(ミュンヘン）
- Year and Date
  2015-04-12 – 2015-04-16
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] IL-17/IFN-受容体遺伝子ダブル欠損NODマウスにおけるリンパ球phenotypeの経時的変化
- Author(s)
  赤澤諭，阿比留教生，古林正和，堀江一郎，安藤隆雄，山崎浩則，川上純
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] インターフェロン誘発１型糖尿病における治療中断後の抗GAD抗体価とインスリン分泌能の推移
- Author(s)
  阿比留教生，赤澤諭，野崎彩，原口愛，池岡俊幸，安井順一，堀江一郎，古林正和，安藤隆雄，川崎英二，山崎浩則，川上純
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24591334
[Presentation] エフェクター細胞を標的にした1型糖尿病発症抑制の試み
- Author(s)
  阿比留教生，赤澤諭，古林正和
- Organizer
  1型糖尿病研究会
- Place of Presentation
  イーグレひめじあいめっせホール（姫路）
- Year and Date
  2014-11-01 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-24591334

1. ABIRU Norio (00380981)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. KOBAYASHI Masakazu (00380874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. KURIYA Genpei (50457579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. NAKAMURA Kan (70530426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Niri Tetsuro (10782550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. KAWASAKI Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. NAGAYAMA Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 堀江一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AKAZAWA Satoru 赤澤 諭

赤澤 諭 アカザワ サトル

Research Projects

Research Products

Co-Researchers

1型糖尿病のエフェクター機能を反映した抗原特異的T細胞マーカーの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the relationship between changes in cellular metabolism within the pancreatic islet environment and the progression of autoimmune diabetes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pioneer fctor-IRF4/8-を標的にした1型糖尿病新規治療開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of effector cell-targeted treatment for the inhibition of type 1 diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapy for type 1 diabetes targeting for IRF-4 (interferon regulatory factor-4)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Haploinsufficiency of interferon regulatory factor 4 strongly protects against autoimmune diabetes in non-obese diabetic mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sequential elevation of autoantibodies to thyroglobulin and glutamic acid decarboxylase in type 1 diabetes.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Pleiotropic roles of transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2023

Author(s)

Organizer

Data Source

[Presentation] NODマウスにおける転写因子IRF4の獲得免疫系と自然免疫系細胞への多面的関与による自己免疫性糖尿病の進展制御について2023

Author(s)

Organizer

Data Source

[Presentation] Pleiotropic roles of transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2023

Author(s)

Organizer

Data Source

[Presentation] 転写因子IRF4の抗原特異的CD4+T細胞および自然免疫系細胞への関与と自己免疫性糖尿病進展への役割について2022

Author(s)

Organizer

Data Source

[Presentation] 転写因子IRF4の抗原特異的CD4+T細胞と自然免疫系細胞を介した糖尿病進展に与える影響の検討2022

Author(s)

Organizer

Data Source

[Presentation] Role of the transcription factor IRF4 on diabetogenic CD4+ T cells and innate immune cells in the development of autoimmune diabetes2021

Author(s)

Organizer

Data Source

[Presentation] IRF4の抗原特異的CD4+T細胞および自然免疫系細胞を介した1型糖尿病における免疫制御機構の解析2021

AKAZAWA Satoru 赤澤諭

赤澤諭アカザワサトル

[Presentation] IL-17/IFN- receptor double-knockout significantly suppresses the development of diabetes compared to the IL-17 single-knockout in the NOD mouse2012