Hayashi Kyoko 林杏子 (大岡杏子)

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Kyoko Hayashi 林杏子

大岡杏子

HAYASHI (OH-OKA) Kyoko 林杏子

大岡

OH-OKA Kyoko 大岡杏子

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Researcher Number	50569019
Other IDs
Affiliation (Current)	2025: 筑波大学, 革新的創薬開発研究センター, 研究員
Affiliation (based on the past Project Information) *help	2023: 筑波大学, 革新的創薬開発研究センター, 研究員 2021 – 2022: 筑波大学, 医学医療系, 特別研究員(RPD) 2018: 筑波大学, 生存ダイナミクス研究センター, 研究員 2017: 筑波大学, 生命領域学際研究センター, 研究員 2016: 山梨大学, 総合研究部, 医学研究員 2015: 山梨大学, 総合研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Gastroenterology / Pediatrics
Keywords	Principal Investigator アレルギー / 抗体治療 / γδT / 乾癬 / 抗体医療 / 免疫受容体 / γδT細胞 / 免疫学 / 芳香族炭化水素受容体 / 炎症性腸疾患 … More / 腸管免疫 / 膠原病学 / 腸内細菌 / 腸管バリア機能 / 小児免疫 Less

Mechanism of gdT cell activation by immunoreceptor CD96Principal Investigator
- Principal Investigator
  
  Kyoko Hayashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  University of Tsukuba
The analysis of new action mechanism of IBD treating medicine 5-ASAPrincipal Investigator
- Principal Investigator
  
  HAYASHI (OH-OKA) Kyoko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
The effect of microbiota on the gut barrier maturationPrincipal Investigator
- Principal Investigator
  
  OH-OKA Kyoko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi

All 2023 2022 2021 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] CD96 Blockade Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis via Suppression of IL-17A Production by Dermal γδ T Cells2022
- Author(s)
  Oh-oka Kyoko、Abe Fumie、Shibuya Akira、Shibuya Kazuko
- Journal Title
  
  The Journal of Immunology
  
  Volume: 209 Issue: 12 Pages: 2313-2321
- DOI
  10.4049/jimmunol.2200502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06943, KAKENHI-PROJECT-20J40217, KAKENHI-PROJECT-21K19369
[Journal Article] 8.Yamashita-Kanemaru Y, Oh-oka K, Abe F, Shibuya K, Shibuya A. Suppression of Th1 and Th17 proinflammatory cytokines and upregulation of Foxp3 expression by a humanized anti-DNAM-1 monoclonal antibody2021
- Author(s)
  Yamashita-Kanemaru Y, Oh-oka K, Abe F, Shibuya K, Shibuya A.
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 40 Issue: 2 Pages: 52-59
- DOI
  10.1089/mab.2020.0042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04836, KAKENHI-PROJECT-21H02708, KAKENHI-PROJECT-20J40217, KAKENHI-PROJECT-21K06943, KAKENHI-PROJECT-21K19369
[Journal Article] Induction of colonic regulatory T cells by 5-aminosalicylic acid (5-ASA) by activating the aryl hydrocarbon receptor.2017
- Author(s)
  Oh-oka K, Kojima Y, Uchida K, Yoda M, Ishimaru K, Nakajima S, Hemmi J, Kano H, Fujii-Kuriyama Y, Katoh R, Ito H, Nakao A
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 1 Pages: 135-151
- DOI
  10.1016/j.jcmgh.2017.03.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-15K19607, KAKENHI-PROJECT-17K15935, KAKENHI-PROJECT-15H04864
[Journal Article] The frequency of Th17 cells in the small intestine exhibits a day-night varidation dependent on circadian clock activity.2017
- Author(s)
  Thu Le HP, Nakamura Y, Oh-Oka K, Ishimaru K, Nakajima S, Nakao A
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 490 (2) Issue: 2 Pages: 290-295
- DOI
  10.1016/j.bbrc.2017.06.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15935, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K09548
[Journal Article] Synergistic anti-tumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.2016
- Author(s)
  1.Hanihara M, Kawataki T, Oh-oka K, Mitsuka K, Nakao A, and Kinouchi H
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: in printing Issue: 6 Pages: 1594-1601
- DOI
  10.3171/2015.5.jns141901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19607, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26870237
[Presentation] 乾癬における免疫受容体CD96の作用機序の解析2023
- Author(s)
  大岡杏子、渋谷彰、渋谷和子
- Organizer
  Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-21K06943
[Presentation] CD96 mediates a costimulatory signal in dermal γδT cells and exacerbates imiquimod-induced psoriasis-like dermatitis.2022
- Author(s)
  Oh-oka K, Shibuya A, Shibuya K
- Organizer
  第86回日本インターフェロン、サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06943
[Presentation] 乾癬における免疫受容体CD96の作用機序の解析。2022
- Author(s)
  大岡杏子、渋谷彰、渋谷和子
- Organizer
  第9回筑波大・理科大合同リトリート
- Data Source
  KAKENHI-PROJECT-21K06943
[Presentation] CD96 blockade ameliorates imiquimod-induced psoriasis-like dermatitis via suppression of IL-17A production by dermal γδ T cells2022
- Author(s)
  Oh-oka K, Shibuya A, Shibuya K
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06943
[Presentation] Involvement of CD96 immunoreceptor on dermal gdT cells in the development of imiquimod-induced psoriasis2021
- Author(s)
  Kyoko Oh-oka;Akira Shibuya;Kazuko Shibuya
- Organizer
  The 50th Annual meeting of the Japanese society for immunology
- Data Source
  KAKENHI-PROJECT-21K06943
[Presentation] 乾癬における免疫受容体CD96の作用機序の解析2019
- Author(s)
  大岡　杏子、渋谷　彰、渋谷　和子
- Organizer
  第7回筑波大学・東京理科大学合同リトリート
- Data Source
  KAKENHI-PROJECT-17K15935
[Presentation] 5-ASA induces the colonic regulatory T cells via the activation of the AhR signaling pathway.2016
- Author(s)
  Oh-oka K, Nakao A
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター (沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19607
[Presentation] レスベラトロール二量体であるε-ビニフェリンによるIgE依存性アレルギー反応の抑制効果.2015
- Author(s)
  齋藤一歩,大岡杏子,久本雅嗣,奥田徹,中尾篤人
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪 (東京都港区)
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K19607

1. 石丸かよ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 渋谷彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Kyoko 林 杏子 (大岡 杏子)

Kyoko Hayashi 林 杏子

大岡杏子

HAYASHI (OH-OKA) Kyoko 林 杏子

大岡

OH-OKA Kyoko 大岡 杏子

Research Projects

Research Products

Co-Researchers

Mechanism of gdT cell activation by immunoreceptor CD96Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The analysis of new action mechanism of IBD treating medicine 5-ASAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of microbiota on the gut barrier maturationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CD96 Blockade Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis via Suppression of IL-17A Production by Dermal γδ T Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 8.Yamashita-Kanemaru Y, Oh-oka K, Abe F, Shibuya K, Shibuya A. Suppression of Th1 and Th17 proinflammatory cytokines and upregulation of Foxp3 expression by a humanized anti-DNAM-1 monoclonal antibody2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of colonic regulatory T cells by 5-aminosalicylic acid (5-ASA) by activating the aryl hydrocarbon receptor.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The frequency of Th17 cells in the small intestine exhibits a day-night varidation dependent on circadian clock activity.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic anti-tumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 乾癬における免疫受容体CD96の作用機序の解析2023

Author(s)

Organizer

Data Source

[Presentation] CD96 mediates a costimulatory signal in dermal γδT cells and exacerbates imiquimod-induced psoriasis-like dermatitis.2022

Author(s)

Organizer

Data Source

[Presentation] 乾癬における免疫受容体CD96の作用機序の解析。2022

Author(s)

Organizer

Data Source

[Presentation] CD96 blockade ameliorates imiquimod-induced psoriasis-like dermatitis via suppression of IL-17A production by dermal γδ T cells2022

Author(s)

Organizer

Data Source

[Presentation] Involvement of CD96 immunoreceptor on dermal gdT cells in the development of imiquimod-induced psoriasis2021

Author(s)

Organizer

Data Source

[Presentation] 乾癬における免疫受容体CD96の作用機序の解析2019

Author(s)

Organizer

Data Source

[Presentation] 5-ASA induces the colonic regulatory T cells via the activation of the AhR signaling pathway.2016

Author(s)

Organizer

Place of Presentation

Hayashi Kyoko 林杏子 (大岡杏子)

Kyoko Hayashi 林杏子

HAYASHI (OH-OKA) Kyoko 林杏子

OH-OKA Kyoko 大岡杏子