Iguchi Akiko 井口研子 (間中研子)

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間中研子

井口研子(間中研子) イグチアキコ

IGUCHI Akiko 井口研子

間中研子

井口研子イグチアキコ

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Researcher Number	50575644
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 筑波大学, 医学医療系, 講師 2012 – 2015: 筑波大学, 医学医療系, 講師 2011: University of Tsukuba, 人間総合科学研究科, 講師
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Tumor immunology
Keywords	Principal Investigator 腫瘍免疫 / CD155 / 免疫チェックポイント分子 / 可溶型CD155 / DNAM-1 / シングルセル遺伝子解析 / 甲状腺未分化癌 / 免疫学 / 癌 / 乳癌 … More / TIL / TIGIT / 免疫逃避 / 細胞免疫 Less

Research for the development of novel immunotherapy for anaplastic thyroid carcinomaPrincipal Investigator
- Principal Investigator
  
  Iguchi Akiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of Tsukuba
Clinicopathological significance of TIGIT and soluble CD155 in breast cancerPrincipal Investigator
- Principal Investigator
  
  Iguchi Akiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  University of Tsukuba
The development of a new molecular target treatment by control of cancer immune escapePrincipal Investigator
- Principal Investigator
  
  Iguchi Akiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  University of Tsukuba
Involvement of soluble CD155 in cancer immune escapePrincipal Investigator
- Principal Investigator
  
  IGUCHI Akiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor immunology
- Research Institution
  University of Tsukuba

All 2022 2020 2019 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Other

[Journal Article] CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT2022
- Author(s)
  Matsuo Tomohei、Iguchi‐Manaka Akiko、Shibuya Akira、Shibuya Kazuko
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 11 Pages: 4001-4004
- DOI
  10.1111/cas.15526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08950, KAKENHI-PROJECT-21K19369
[Journal Article] Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.2020
- Author(s)
  Okumura G, Iguchi-Manaka A,Murata R,Yamashita-Kanemaru Y, Shibuya A, Shibuya K
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 217(4) Issue: 4
- DOI
  10.1084/jem.20191290
- NAID
  120007165432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-18J21441, KAKENHI-PROJECT-17K10533
[Journal Article] Increased soluble CD155 in the serum of cancer patients2016
- Author(s)
  Iguchi-Manaka A, Okumura G, Kojima H, Cho Y, Hirochika R, Bando H, Sato T, Yoshikawa H, Hara H, Shibuya A, Shibuya K.
- Journal Title
  
  PLoS One
  
  Volume: 11(4) Issue: 4 Pages: 1-12
- DOI
  10.1371/journal.pone.0152982
- NAID
  120007135543
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15659, KAKENHI-PROJECT-26670575, KAKENHI-PROJECT-25293091, KAKENHI-PROJECT-26861038, KAKENHI-PUBLICLY-15H01365, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-16H05169, KAKENHI-PROJECT-16K14629, KAKENHI-PROJECT-16K15455
[Presentation] CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT.2022
- Author(s)
  松尾知平、井口研子、渋谷彰、渋谷和子
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08950
[Presentation] 新規免疫チェックポイント阻害療法開発への取り組み2022
- Author(s)
  井口研子、松尾知平、原尚人、渋谷和子、渋谷彰
- Organizer
  第34回日本内分泌外科学会総会
- Data Source
  KAKENHI-PROJECT-20K08950
[Presentation] Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.2019
- Author(s)
  Okumura G, Iguchi-Manaka A, Murata R, Yamashita-Kanemaru Y, Shibuya A, Shibuya K
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10533
[Presentation] 乳癌における可溶型CD155の発現解析2017
- Author(s)
  井口研子、渋谷和子、市岡恵美香、都島由希子、池田達彦、坂東裕子、渋谷彰、原尚人
- Organizer
  第25回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10533
[Presentation] 癌患者血清における可溶型CD155の発現解析2017
- Author(s)
  井口研子、渋谷彰、渋谷和子
- Organizer
  第9回血液疾患免疫療法学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10533
[Presentation] Soluble CD155 is involved in the escape from tumor immunity2015
- Author(s)
  IGUCHI Akiko
- Organizer
  第5回新学術発がんスパイラル国際シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2015-02-26
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] Increased soluble CD155 in the serum of cancer patients2015
- Author(s)
  Iguchi A, Kojima H, Cho Y, Shibuya A, Shibuya K
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] Soluble CD155 is involved in the escape from tumor immunity2015
- Author(s)
  IGUCHI Akiko
- Organizer
  第3回筑波大学・東京理科大学生命医科学研究所合同リトリート
- Place of Presentation
  野田
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] Increased soluble CD155 in patients with various cancers2015
- Author(s)
  Iguchi A, Shibuya A, Shibuya K
- Organizer
  2015日本免疫学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] 癌患者血清における可溶型CD155の上昇2015
- Author(s)
  井口研子、渋谷彰、渋谷和子
- Organizer
  第7回血液疾患免疫療法研究会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] The role of DNAM-1 and CD155 in tumor immunity and escape2015
- Author(s)
  Shibuya K, Iguchi Akiko, Kojima H, Cho Y, Hirochika R, Shibuya A
- Organizer
  International Symposium on Immune Regulation
- Place of Presentation
  茨城県大洗町
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] 腫瘍免疫逃避機構における可溶型CD155の役割2014
- Author(s)
  井口研子
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] 腫瘍免疫逃避機構における可溶型CD155の役割2014
- Author(s)
  井口研子
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館、京都市
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] Involvement of soluble CD155 in cancer immune escape2013
- Author(s)
  Akiko Iguchi
- Organizer
  2013日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] Involvement of soluble CD155 in cancer immune escape2013
- Author(s)
  Akiko Iguchi
- Organizer
  2013日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] Involvement of soluble CD155 in cancer immune escape2013
- Author(s)
  Akiko Iguchi
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] Involvement of soluble CD155 in cancer immune escape2013
- Author(s)
  Akiko Iguchi
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23701072
[Presentation] 腫瘍免疫逃避機構における可溶型CD155の役割
- Author(s)
  井口研子
- Organizer
  第23回乳癌基礎研究会
- Place of Presentation
  つくば
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] Soluble CD155 is involved in the escape from tumor immunity.
- Author(s)
  IGUCHI Akiko
- Organizer
  第43回日本免疫学会総会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] Involement of soluble CD155 in cancer immune escape
- Author(s)
  IGUCHI Akiko
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861038
[Presentation] 腫瘍免疫逃避機構における可溶型CD155の役割
- Author(s)
  井口研子
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-26861038
[]

1. 渋谷彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Iguchi Akiko 井口 研子 (間中 研子)

間中研子

井口 研子(間中研子) イグチ アキコ

IGUCHI Akiko 井口 研子

間中 研子

井口 研子 イグチ アキコ

Research Projects

Research Products

Co-Researchers

Research for the development of novel immunotherapy for anaplastic thyroid carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinicopathological significance of TIGIT and soluble CD155 in breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of a new molecular target treatment by control of cancer immune escapePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of soluble CD155 in cancer immune escapePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Increased soluble CD155 in the serum of cancer patients2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT.2022

Author(s)

Organizer

Data Source

[Presentation] 新規免疫チェックポイント阻害療法開発への取り組み2022

Author(s)

Organizer

Data Source

[Presentation] Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.2019

Author(s)

Organizer

Data Source

[Presentation] 乳癌における可溶型CD155の発現解析2017

Author(s)

Organizer

Data Source

[Presentation] 癌患者血清における可溶型CD155の発現解析2017

Author(s)

Organizer

Data Source

[Presentation] Soluble CD155 is involved in the escape from tumor immunity2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Increased soluble CD155 in the serum of cancer patients2015

Author(s)

Organizer

Place of Presentation

Iguchi Akiko 井口研子 (間中研子)

井口研子(間中研子) イグチアキコ

IGUCHI Akiko 井口研子

間中研子

井口研子イグチアキコ