Izumi Natsuko 泉奈津子

… Alternative Names

泉奈津子イズミナツコ

Less

Researcher Number	50579274
Other IDs
Affiliation (Current)	2025: 東京大学, 定量生命科学研究所, 技術専門職員
Affiliation (based on the past Project Information) *help	2023: 東京大学, 定量生命科学研究所, 技術専門職員 2020 – 2021: 東京大学, 定量生命科学研究所, 技術専門職員 2018 – 2019: 東京大学, 定量生命科学研究所, 助教 2017: 東京大学, 分子細胞生物学研究所, 助教 2014 – 2015: 東京大学, 分子細胞生物学研究所, 助教 2010 – 2011: 東京大学, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Molecular biology / System genome science
Keywords	Principal Investigator piRNA / BmAgo3 / RNAサイレンシング / ピンポンサイクル / リン酸化 / Ago3 / Gtsf / Siwi / トランスポゾン / トリミング … More / ヌクレアーゼ / Zucchini / Trimmer / 核酸 / ゲノム / 発現制御 / 翻訳抑制 / mRNP / miRNA Less

Analysis of factors enriched in a PIWI protein complex by inhibition of the ping-pong cyclePrincipal Investigator
- Principal Investigator
  
  泉奈津子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  The University of Tokyo
Analysis of the regulation of BmAgo3 phosphorylationPrincipal Investigator
- Principal Investigator
  
  Natsuko Izumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  The University of Tokyo
Analysis of two exonucleases in the 3' end formation of piRNAsPrincipal Investigator
- Principal Investigator
  
  Izumi Natsuko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  System genome science
- Research Institution
  The University of Tokyo
Analysis of 3'-end formation mechanism of piRNAs involved in the silencing of transposonsPrincipal Investigator
- Principal Investigator
  
  Izumi Natsuko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
mRNP精製システムを用いたmiRNA作用機序の解析Principal Investigator
- Principal Investigator
  
  泉奈津子
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo

All 2024 2023 2021 2020 2018 2017 2016 2015 2014 2011 Other

All Journal Article Presentation

[Journal Article] The dual role of Spn-E in supporting heterotypic ping-pong piRNA amplification in silkworms2024
- Author(s)
  Natsuko Izumi, Keisuke Shoji, Lumi Negishi, and Yukihide Tomari
- Journal Title
  
  EMBO Reports
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05632
[Journal Article] Non-gonadal somatic piRNA pathways ensure sexual differentiation, larval growth, and wing development in silkworms2023
- Author(s)
  Kiuchi Takashi、Shoji Keisuke、Izumi Natsuko、Tomari Yukihide、Katsuma Susumu
- Journal Title
  
  PLOS Genetics
  
  Volume: 19 Issue: 9 Pages: e1010912-e1010912
- DOI
  10.1371/journal.pgen.1010912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05632, KAKENHI-PLANNED-21H05278
[Journal Article] RNase κ promotes robust piRNA production by generating 2',3'-cyclic phosphate-containing precursors.2021
- Author(s)
  Shigematsu M, Kawamura T, Morichika K, Izumi N, Kiuchi T, Honda S, Pliatsika V, Matsubara R, Rigoutsos I, Katsuma S, Tomari Y, Kirino Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 4498-4498
- DOI
  10.1038/s41467-021-24681-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06484, KAKENHI-PLANNED-17H06431, KAKENHI-PROJECT-18H05271
[Journal Article] Dynamic subcellular compartmentalization ensures the fidelity of piRNA biogenesis in silkworms2021
- Author(s)
  Pui Yuen Chung, Keisuke Shoji, Natsuko Izumi, and Yukihide Tomari
- Journal Title
  
  EMBO reports
  
  Volume: - Issue: 7
- DOI
  10.15252/embr.202051342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06484, KAKENHI-PROJECT-20J11535
[Journal Article] Zucchini consensus motifs determine the mechanism of pre-piRNA production2020
- Author(s)
  Izumi Natsuko、Shoji Keisuke、Suzuki Yutaka、Katsuma Susumu、Tomari Yukihide
- Journal Title
  
  Nature
  
  Volume: 578 Issue: 7794 Pages: 311-316
- DOI
  10.1038/s41586-020-1966-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06484, KAKENHI-PROJECT-18H05271, KAKENHI-PROJECT-17J02408, KAKENHI-PLANNED-17H06431
[Journal Article] Transcriptome profiling reveals infection strategy of an insect maculavirus2018
- Author(s)
  Katsuma Susumu、Kawamoto Munetaka、Shoji Keisuke、Aizawa Takahiro、Kiuchi Takashi、Izumi Natsuko、Ogawa Moe、Mashiko Takaaki、Kawasaki Hideki、Sugano Sumio、Tomari Yukihide、Suzuki Yutaka、Iwanaga Masashi
- Journal Title
  
  DNA Research
  
  Volume: 印刷中 Issue: 3 Pages: 277-286
- DOI
  10.1093/dnares/dsx056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08095, KAKENHI-PROJECT-17K17673, KAKENHI-PROJECT-15H02482, KAKENHI-PROJECT-17J02408, KAKENHI-PROJECT-16H05051, KAKENHI-PROJECT-16H06279
[Journal Article] PNLDC1, mouse pre-piRNA Trimmer, is required for meiotic and post-meiotic male germ cell development.2018
- Author(s)
  Nishimura T, Nagamori I, Nakatani T, Izumi N, Tomari Y, Kuramochi-Miyagawa S, Nakano T.
- Journal Title
  
  EMBO Rep.
  
  Volume: - Issue: 3
- DOI
  10.15252/embr.201744957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17673, KAKENHI-PROJECT-15H02509, KAKENHI-PROJECT-15H04699
[Journal Article] Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.2017
- Author(s)
  Zhang H, Liu K, Izumi N, Huang H, Ding D, Ni Z, Sidhu SS, Chen C, Tomari Y, Min J.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 47 Pages: 12483-12488
- DOI
  10.1073/pnas.1711486114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17673, KAKENHI-INTERNATIONAL-15K21720, KAKENHI-PLANNED-26113007
[Journal Article] Identification and functional analysis of the pre-piRNA 3′ Trimmer in silkworms.2016
- Author(s)
  Izumi N, Shoji K, Sakaguchi Y, Honda S, Kirino Y, Suzuki T, Katsuma S, Tomari Y
- Journal Title
  
  Cell
  
  Volume: 164 Issue: 5 Pages: 962-973
- DOI
  10.1016/j.cell.2016.01.008
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26891004, KAKENHI-PROJECT-15J00469, KAKENHI-PROJECT-25291007, KAKENHI-PLANNED-26113007
[Journal Article] The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs.2014
- Author(s)
  Wang W, Yoshikawa M, Han BW, Izumi N, Tomari Y, Weng Z, Zamore PD
- Journal Title
  
  Mol Cell
  
  Volume: 56 Issue: 5 Pages: 708-716
- DOI
  10.1016/j.molcel.2014.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26891004, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113007
[Journal Article] The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.2011
- Author(s)
  Arias-Palomo E, Yamashita A, Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca O.
- Journal Title
  
  Genes and Development
  
  Volume: 15 Pages: 153-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22870027
[Presentation] Analysis of 3′-end formation of silkworm piRNAs using Trimmer knockout cell line2018
- Author(s)
  Natsuko Izumi, Keisuke Shoji, Yukihide Tomari
- Organizer
  日本RNA学会
- Data Source
  KAKENHI-PROJECT-17K17673
[Presentation] Identification of pre-piRNA trimming enzyme “Trimmer” in the silkworm2015
- Author(s)
  Natsuko Izumi, Keisuke Shoji, Yuriko Sakaguchi, Tsutomu Suzuki, Susumu Katsuma, Yukihide Tomari
- Organizer
  日本RNA学会
- Place of Presentation
  札幌, ホテルライフォート札幌
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26891004
[Presentation] A biochemical approach to identify “Trimmer,” the pre-piRNA 3’-end processing enzyme
- Author(s)
  Natsuko Izumi and Yukihide Tomari
- Organizer
  Joint Australia and Japan RNA Meeting (jajRNA 2014)
- Place of Presentation
  オーストラリア (シドニー)
- Year and Date
  2014-11-02 – 2014-11-05
- Data Source
  KAKENHI-PROJECT-26891004

1. SHOJI Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 岩永将司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Izumi Natsuko 泉 奈津子

泉 奈津子 イズミ ナツコ

Research Projects

Research Products

Co-Researchers

Analysis of factors enriched in a PIWI protein complex by inhibition of the ping-pong cyclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the regulation of BmAgo3 phosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of two exonucleases in the 3' end formation of piRNAsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of 3'-end formation mechanism of piRNAs involved in the silencing of transposonsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

mRNP精製システムを用いたmiRNA作用機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The dual role of Spn-E in supporting heterotypic ping-pong piRNA amplification in silkworms2024

Author(s)

Journal Title

Data Source

[Journal Article] Non-gonadal somatic piRNA pathways ensure sexual differentiation, larval growth, and wing development in silkworms2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNase κ promotes robust piRNA production by generating 2',3'-cyclic phosphate-containing precursors.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic subcellular compartmentalization ensures the fidelity of piRNA biogenesis in silkworms2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Zucchini consensus motifs determine the mechanism of pre-piRNA production2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptome profiling reveals infection strategy of an insect maculavirus2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PNLDC1, mouse pre-piRNA Trimmer, is required for meiotic and post-meiotic male germ cell development.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and functional analysis of the pre-piRNA 3′ Trimmer in silkworms.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs.2014

Izumi Natsuko 泉奈津子

泉奈津子イズミナツコ