Kozaka Takashi 小阪孝史

… Alternative Names

KOZAKA Takashi 小阪孝史

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Researcher Number	50579836
Other IDs	https://orcid.org/0009-0007-2580-2738
External Links
Affiliation (Current)	2024: 金沢大学, 疾患モデル総合研究センター, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 金沢大学, 疾患モデル総合研究センター, 助教 2011 – 2021: 金沢大学, 学際科学実験センター, 助教
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator σ-2受容体 / イメージング / vesamicol / σ受容体 / シグマ受容体 / ベサミコール / シグマ-2受容体 / 中枢神経系疾患 / イメージング剤 / イメージングプローブ … More / シグマ（σ）受容体 / BNCT / ホウ素含有イメージング剤 / 分子イメージング / 脳内σ-1受容体 / 選択的σ-2受容体リガンド … More Except Principal Investigator ベサミコール類似体 / SPECT / アセチルコリントランスポーター / 分子イメージング / アルツハイマー病 / 早期診断 / 放射性医薬品 / シグマ－１受容体 / OI5V / （+)-OI5V / vesamicol誘導体 / ストレス / σ-1受容体 / ストレス性疾患 / SPECT/CT / イメージング剤 / シグマ-1受容体 / ベサミコール / 光学分割 / アセチルコリントランスポータ / PET / ベサミコール類縁体 / PET用分子イメージング剤 / (-)-[11C]OMDV / アセチルコリントランスポーター(VAChT) / 早期診断薬 / ＰＥＴ / ＳＰＥＣＴ / コリン作動性神経系 / コリン作動性神経 Less

Development of CNS disease imaging probes targeting sigma-2 receptorsPrincipal Investigator
- Principal Investigator
  
  小阪孝史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of Novel Solid Tumor Imaging Agents Targeting the sigma ReceptorPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of sigma-1 receptor imaging agent for early diagnosis of stress-related diseases
- Principal Investigator
  
  Shiba Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Development of a new sigma-2 receptor ligand for imaging and BNCTPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of the sigma-2 receptor imaging agent for the purpose of early detection and the proliferation potency diagnosis of the solid tumorPrincipal Investigator
- Principal Investigator
  
  Kozaka Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
The development of the presynaptic cholinergic nerve molecules imaging agent for early diagnosis of Alzheimer's disease
- Principal Investigator
  
  Shiba Kazuhiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of the Colin transporter imaging agent for early diagnosis of Alzheimer's disease
- Principal Investigator
  
  SHIBA Kazuhiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
The imaging study of sigma-1 receptor in the brain for the objective evaluation method of the disease caused by aging or stressPrincipal Investigator
- Principal Investigator
  
  KOZAKA Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] 125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia2023
- Author(s)
  Wakabayashi Hiroshi、Mori Hiroshi、Hiromasa Tomo、Akatani Norihito、Inaki Anri、Kozaka Takashi、Kitamura Yoji、Ogawa Kazuma、Kinuya Seigo、Taki Junichi
- Journal Title
  
  Journal of Nuclear Cardiology
  
  Volume: 30 Issue: 2 Pages: 653-661
- DOI
  10.1007/s12350-022-03064-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08047, KAKENHI-PROJECT-20K08102, KAKENHI-PROJECT-22K15841, KAKENHI-PROJECT-23K07152
[Journal Article] In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.2021
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Kazuhiro Shiba.
- Journal Title
  
  Ann Nucl Med.
  
  Volume: 35 Issue: 2 Pages: 165-175
- DOI
  10.1007/s12149-020-01552-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08197, KAKENHI-PROJECT-20K07991, KAKENHI-PROJECT-20K08047, KAKENHI-PROJECT-20K08102, KAKENHI-PROJECT-19H03598
[Journal Article] (－)‐o‐[11C]methyl‐trans‐decalinvesamicol ((－)‐[11C]OMDV) as a PET ligand for the vesicular acetylcholine transporter2020
- Author(s)
  Miwa Daisuke、Kitamura Yoji、Kozaka Takashi、Shigeno Taiki、Ogawa Kazuma、Taki Junichi、Kinuya Seigo、Shiba Kazuhiro
- Journal Title
  
  Synapse
  
  Volume: 74 Issue: 11
- DOI
  10.1002/syn.22176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07991, KAKENHI-PROJECT-20K08102
[Journal Article] Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging2019
- Author(s)
  Ogawa Kazuma、Masuda Ryohei、Mishiro Kenji、Wang Mengfei、Kozaka Takashi、Shiba Kazuhiro、Kinuya Seigo、Odani Akira
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 18 Issue: 10 Pages: 31998-31999
- DOI
  10.1016/j.bmc.2019.03.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02668, KAKENHI-PROJECT-17K10355
[Journal Article] Development of a novel radiobromine-labeled sigma-1 receptor imaging probe2018
- Author(s)
  Kazuma Ogawa, Ryohei Masuda, Yoshiaki Mizuno, Akira Makino, Takashi Kozaka, Yoji Kitamura, Yasushi Kiyono, Kazuhiro Shiba, Akira Odani
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 61 Pages: 28-35
- DOI
  10.1016/j.nucmedbio.2018.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10355
[Journal Article] In vivo differences between two optical isomers of radioiodinated o-iodo-trans-decalinvesamicol for use as a radioligand for the vesicular acetylcholine transporter.2016
- Author(s)
  Uno I, KOzaka T, Miwa D, Kitamura Y, M.A Azim, Ogawa K, Taki J, Kinuya S, Shiba K.
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1371/journal.pone.0146719
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273, KAKENHI-PROJECT-15K09886
[Journal Article] Synthesis and evaluation of a new vesamicol analog o-[11C]methyl-trans-decalinvesamicol as a PET ligand for the vesicular acetylcholine transporter.2015
- Author(s)
  Kitamura Y., Kozaka T., Miwa D., Uno I., Azim M. A.-u., Ogawa K., Taki J., Kinuya S. and Shiba K.
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 30 Issue: 2 Pages: 122-129
- DOI
  10.1007/s12149-015-1039-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09886, KAKENHI-PROJECT-26293273, KAKENHI-PROJECT-26461847
[Journal Article] Regional brain imaging of vesicular acetylcholine transporter (VAChT) using o-[^<12>5I]iodo-trans-decalin vesamicol as a new potential imaging probe2014
- Author(s)
  Kozaka, T., Uno, I., Kitamura, Y., Miwa, D., Azim,MA., Ogawa, K. Shiba. K
- Journal Title
  
  Synapse
  
  Volume: Vol. 68 Issue: 3 Pages: 107-113
- DOI
  10.1002/syn.21720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813, KAKENHI-PROJECT-24591812
[Journal Article] Regional brain imaging of vesicular acetylcholine transporter (VAChT) using o-[125I]iodo-trans-decalinvesamicol as a new potential imaging probe.2014
- Author(s)
  Takashi Kozaka, Izumi Uno, Yoji Kitamura, Daisuke Miwa, Mohammad Anwar-ul Azim, Kazuma Ogawa, Kazuhiro Shiba.
- Journal Title
  
  Synapse
  
  Volume: 68 Pages: 107-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813
[Journal Article] Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT).2012
- Author(s)
  Takashi Kozaka, Izumi Uno, Yoji Kitamura, Daisuke Miwa, Kazuma Ogawa, Kazuhiro Shiba.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 20 Pages: 4936-4941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813
[Journal Article] Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT)2012
- Author(s)
  Kozaka, T., Uno, I., Kitamura, Y., Miwa, D., Ogawa, K., Shiba, K
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: Vol.20 Issue: 16 Pages: 4936-4941
- DOI
  10.1016/j.bmc.2012.06.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591813, KAKENHI-PROJECT-24591812
[Presentation] 新規σ-2受容体リガンドMILVの開発とイメージング剤としての基礎評価2024
- Author(s)
  小阪孝史, 北村陽二, 小川数馬, 木村寛之
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] Dynamic Expression of Myocardial Sigma-1 Receptor in Doxorubicin-Induced Cardiomyopathy using Radioiodine Labeled 2-[4- (2iodophenyl)piperidino]cyclopentanol (OI5V) Imaging2023
- Author(s)
  Chen Z, Wakabayashi H, Mori H, Hiromasa T, Zhang X, Kozaka T, Ogawa K, Kinuya S, Taki J
- Organizer
  Congress of European Association of Nuclear Medicine 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] Positive Protective Effects of Sigma-1 Receptor Stimulation with Fluvoxamine after Myocardial Ischemia and Reperfusion in Rat2023
- Author(s)
  Zhang X, Wakabayashi H, Mori H, Hiromasa T, Chen Z, Kozaka T, Ogawa K, Kinuya S, Taki J
- Organizer
  Congress of European Association of Nuclear Medicine 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07152
[Presentation] 125I-Labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) imaging Visualized Augmented Sigma-1 Receptor Expression by Depending on the Severity of Myocardial Ischemia2022
- Author(s)
  Hiroshi Wakabayashi, Junichi Taki, Hiroshi Mori, Tomo Hiromasa, Norihito Akatani, Anri Inaki, Takashi Kozaka, Yoji Kitamura, Kazuma Ogawa, Seigo Kinuya
- Organizer
  第13回世界核医学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07991
[Presentation] Development of PET / SPECT probes for Vesicular acetylcholine transporter (VAChT) imaging2021
- Author(s)
  小阪孝史
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07991
[Presentation] ストレス負荷マウスにおけるストレス強度と局所脳血流量の関係2020
- Author(s)
  野坂朋代、池田朝海、北村陽二、小阪孝史、小川数馬、柴和弘
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] VAChTイメージング剤(OIDV)の脳内移行性におけるP糖蛋白の影響2019
- Author(s)
  小阪孝史, 髙橋茉衣夏, 北村陽二, 池田朝海, 小川数馬, 柴和弘
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] (+)-[125/123I]OI5Vのシグマ-1受容体イメージング剤としての基礎的評価2019
- Author(s)
  高橋茉衣夏、小阪孝史、北村陽二、池田朝海、小川数馬、柴和弘
- Organizer
  第59回日本核医学学術総会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ストレス負荷マウスにおけるコリン作動性神経系(VAChT)の変化2019
- Author(s)
  柴和弘, 髙橋茉衣夏, 北村陽二, 小阪孝史, 池田朝海, 小川数馬
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] [125I]OI5Vによる15q重複Tgマウス（自閉症マウス）の脳内σ-1受容体密度測定2019
- Author(s)
  髙橋茉衣夏, 小阪孝史, 北村陽二, 池田朝海, 小川数馬, 柴和弘
- Organizer
  日本薬学会第139年会（幕張メッセ，千葉）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] Usefulness of radioiodinated 2-[4-(2-iodophenyl)piperidino]cyclopentanol(OI5V) for early diagnosing neurodegenerative disorder caused by stress.2018
- Author(s)
  Shigeno T, Takahashi M, Kozaka T, Kitamura Y, Kamide M, Hamamoto M, Yoshida K, Ogawa K, Shiba K.
- Organizer
  12th World Congress of the World Federation of Nuclear Medicine and Biology. （Melbourne, Australlia）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ストレス性精神疾患の早期診断用新規イメーイング剤の開発2018
- Author(s)
  高橋茉衣夏、茂野泰貴、小阪孝史、北村陽二、上出茉歩、濱本萌凪、吉田楓、小川数馬、柴　和弘
- Organizer
  第58回日本核医学会学術総会（沖縄コンベンションセンター，沖縄）
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] ヒト染色体15番長腕重複モデルマウスのストレス負荷によるドーパミン受容体への影響2017
- Author(s)
  北嶋祥太郎，小澤梓，北村陽二，小阪孝史，茂野泰貴，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] [123I]OI5Vの新規シグマ-1受容体イメージング剤としての評価2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴　和弘
- Organizer
  第15回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2017)
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] 5員環を有するvesamicol類縁体のシグマ-1受容体イメージング剤としての基礎的評価2017
- Author(s)
  茂野泰貴，小阪孝史，北村陽二，石山史奈，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 環サイズの異なるvesamicol類縁体の小胞アセチルコリントランスポーター及びシグマ受容体との構造活性相関2017
- Author(s)
  石山史奈，小阪孝史，高橋茉衣夏，北村陽二，茂野泰貴，小川数馬，柴　和弘
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 1,2環サイズの異なるvesamicol類縁体の小胞アセチルコリントランスポーター及びシグマ受容体との構造活性相関2017
- Author(s)
  石山　史奈、小阪　孝史、高橋　茉衣夏、北村　陽二、茂野　泰貴、小川　数馬、柴　和弘
- Organizer
  日本薬学会　第137年会
- Place of Presentation
  仙台国際センター　(仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] Characteristics of 2-[4-(2-iodophenyl)piperidino]cyclopenntanon (OI5V) as a new siguma-1 receptor imaging agent.2017
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Rina Ishiyama, Kazuma Ogawa, Kazuhiro Shiba
- Organizer
  SNMMI 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規SPECT用シグマ-1受容体イメージング剤の開発研究2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴和弘
- Organizer
  第12回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] Characteristics of 2-[4-(2-iodophenyl)piperidino]cyclopentanol(OI5V) as a new sigma-1 receptor imaging agent2017
- Author(s)
  Taiki Shigeno, Takashi Kozaka, Yoji Kitamura, Rina Ishiyama, Kazuma Ogawa, Kazuhiro Shiba
- Organizer
  2017 SNMMI 64th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10355
[Presentation] 新規SPECT用シグマ-1受容体イメージング剤の開発研究2017
- Author(s)
  茂野泰貴、小阪孝史、北村陽二、小川数馬、柴　和弘
- Organizer
  日本分子イメージング学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] In vitro Evaluation of meta-bromo benzovesamicol (MBBzV) as a Potential Vesicular Acetylcholine Transporter (VAChT) Imaging Probe2016
- Author(s)
  Azim MA, Kozaka T, Uno I, Miwa D, Kitamura Y, Shiba K.
- Organizer
  The 2nd Asian Nuclear Medicine Academic Forum 2016
- Place of Presentation
  Shanghai, China
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] In vitro evaluation meta-bromo benzovesamicol as PET VAChT imaging Probe.2016
- Author(s)
  Azim MA, Kozaka T, Uno I, Miwa D, Kitamura Y, Shiba K.
- Organizer
  he 2nd Asian Nuclear Medicine Academic Forum 2016,(ANMAF 2016)
- Place of Presentation
  Shanghai, China.
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] SPECT用σ-2受容体イメージング剤[123I]PIDVの開発研究2016
- Author(s)
  小阪孝史、緩詰沙耶、茂野泰貴、北村陽二、小川数馬、川井恵一、絹谷清剛、柴和弘
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 有機合成化学を基盤とした分子イメージング研究2016
- Author(s)
  小阪孝史
- Organizer
  平成28年度北信越若手有機合成化学若手研究会
- Place of Presentation
  金沢
- Year and Date
  2016-04-02
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Development of a radiobromine-labeled compound as a sigma receptor ligand for tumor imaging2016
- Author(s)
  Mizuno Y, Makino A, Masuda R, Kozaka T, Kitamura Y, Kiyono Y, Shiba K, Odani A
- Organizer
  2016 SNMMI 63th annual meeting
- Place of Presentation
  Sangiego, USA
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Vesamicolを母核とする新規σ-2受容体選択的リガンドの開発研究2016
- Author(s)
  小阪孝史, 柴山怜子, 稲垣冬彦, 向智里, 北村陽二, 小川数馬, 柴和弘
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 111In標識八臭素化ポルフィリン誘導体の腫瘍イメージング剤としての開発研究2016
- Author(s)
  北村陽二、小川数馬、小阪孝史、茂野泰貴、北嶋祥太郎、石山史奈、中島美由紀、御舩正樹、川井恵一、絹谷清剛、斎藤寛、柴和弘
- Organizer
  第11回日本分子イメージング学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-05-29
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] Evaluation of radiolabeled o-bromo- decalinvesamicol (OBDV) as a PET ligand for the Vesicular Acetylcholine Transporter (VAChT)2014
- Author(s)
  Azim, MA., Kozaka, T., Uno, I., Miwa, D., Kitamura, Y., Ogawa, K., Kawai, K., Makino, A., Kiyono, Y and Shiba, K
- Organizer
  International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology
- Place of Presentation
  ユアーズホテルフクイ(福井市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用イメージング剤[11C]OMDVの光学分割と動態評価2014
- Author(s)
  三輪大輔、小阪孝史、北村陽二、Mohammad A. Azim,　黒宮里紗、緩詰沙耶、小川数馬、川井恵一、柴　和弘
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規σ－２受容体イメージング剤ＰＩＤＶの開発研究2014
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Mohammad A. Azim、黒宮里紗、北村陽二、小川数馬、川井恵一、柴和弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  大阪府豊中市・千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791400
[Presentation] Evaluation of radiolabeled o-bromo-decalinvesamicol (OBDV) as a PET ligand for the Vesicular Acetylcholine Transporter (VAChT).2014
- Author(s)
  Mohammad Anwar-ul Azim , Takashi Kozaka, Izumi Uno, Daisuke Miwa, Yoji Kitamura, Kazuma Ogawa, Keiichi Kawai, Akira Makino, Yasushi Kiyono, Kazuhiro Shiba.
- Organizer
  International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology.
- Place of Presentation
  ユアーズホテルフクイ、福井市、福井県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] Introduction of radiobromine labeled decalinvesamicol analogue as a new and promising PET vesicular acetylcholine transporter (VAChT) imaging probe.2014
- Author(s)
  Mohammad Anwar-ul Azim, Takashi Kozaka, Izumi Uno, Daisuke Miwa, Yoji Kitamura, Kazuma Ogawa, Keiichi Kawai, Yasushi Kiyono, Kazuhiro Shiba.
- Organizer
  SNMMI 61th annual meeting.
- Place of Presentation
  Louis Convention Center, St. Louis. USA.
- Year and Date
  2014-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293273
[Presentation] 新規σ-2受容体イメージング剤PIDVの開発研究2014
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Mohammad A. Azim、黒宮里紗、北村陽二、小川数馬川井恵一、柴和弘
- Organizer
  日本分子イメージング学会第9回学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-23791400
[Presentation] The development of potential vesicular acetylcholine transporter (VAChT) PET imaging probes2013
- Author(s)
  Kozaka T, Miwa D, Uno I, Kitamura Y, Azim MA, Ogawa K, Kinuya S, Kawai K, Shiba K
- Organizer
  2013 SNMMI 60th annual meeting. Vancouber Convention Centre
- Place of Presentation
  Vancouber, BC, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] アルツハイマー病の早期診断を目的とした新規PET用VAChTイメージング剤[^<11>C]OMDVの合成とin vivo評価2013
- Author(s)
  小阪孝史、三輪大輔、鵜野いずみ、北村陽二、Mohammad Anwer-ul AZIM,川村和紀、小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] In vivo evaluation of radioiodinated o-iodo-trans-decalinvesamicol（ＯＩＤＶ） as a vesicular acetylcholine transporter (VAChT) imaging agent.2013
- Author(s)
  Uno I, Kozaka T, Kitamura Y, Miwa D, Azim MA, Ogawa K, Kawai K, Taki J, Kinuya S, Shiba K.
- Organizer
  2013 SNMMI 60th annual meeting.
- Place of Presentation
  Vancouber Convention Centre, Vancouber, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] The development of potential vesicular acetylcholine transporter (VAChT) PET imaging probes.2013
- Author(s)
  Kozaka T, Miwa D, Uno I, Kitamura Y, Azim MA, Ogawa K, Kinuya S, Kawai K, Shiba K.
- Organizer
  2013 SNMMI 60th annual meeting.
- Place of Presentation
  Vancouber Convention Centre, Vancouber, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用[125I]OIDVのジアステレオマー分離と in vivo 脳内動態変化2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Azim Mohammad A、小川数馬、川井恵一、柴和弘.
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサ、静岡市、静岡県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] In vivo evaluation of radioiodinated o-iodo-trans- decalinvesamicol(OIDV)as a vesicular acetylcholine transporter (VAChT) imaging agent2013
- Author(s)
  Uno I, Kozaka T, Kitamura Y, Miwa D, Azim MA, Ogawa K, Kawai K, Taki J, Kinuya S, Shiba K
- Organizer
  2013 SNMMI 60th annual meeting
- Place of Presentation
  Vancouber Convention Centre, Vancouber, BC, Canada
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] アルツハイマー病の早期診断を目的とした新規PET用VAChTイメージング剤[11C]OMDVの合成とin vivo 評価2013
- Author(s)
  小阪孝史、三輪大輔、鵜野いずみ、北村陽二、Mohammad Anwer-ul AZIM,　川村和紀、小川数馬、川井恵一、柴　和弘
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 脳内小胞アセチルコリントランスポーター(VAChT)のPETイメージングプローブ[^<11>C]OMDVの開発2013
- Author(s)
  三輪大輔,小阪孝史,鵜野いずみ,北村陽二, Azim Mohammad A.,河村和紀,小川数馬,川井恵一,柴和弘
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサおよび三保園ホテル(静岡市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 脳内小胞アセチルコリントランスポーター（VAChT）のPETイメージングプローブ[11C]OMDVの開発,2013
- Author(s)
  三輪大輔, 小阪孝史, 鵜野いずみ, 北村陽二, Azim Mohammad A., 河村和紀, 小川数馬, 川井恵一, 柴和弘,
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサ、静岡市、静岡県
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] OIDVのジアステレオマー分離とその選択的VAChTイメージング剤としての評価2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Mohammad Anwer-ul AZIM,小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用[^<125>I]OIDVのジアステレオマー分離とin vivo脳内動態変化2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Azim Mohammad A、小川数馬、川井恵一、柴和弘
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  清水テルサおよび三保園ホテル(静岡市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] OIDVのジアステレオマー分離とその選択的VAChTイメージング剤としての評価2013
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、Mohammad Anwer-ul AZIM,　小川数馬、川井恵一、柴　和弘
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用VAChTイメージング剤の開発研究2012
- Author(s)
  小阪孝史,三輪大輔,鵜野いずみ,北村陽二,Azim Mohammad Anwar-ul,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ,京都市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] PET用VAChTイメージング剤の開発研究2012
- Author(s)
  小阪孝史，三輪大輔，鵜野いずみ，北村陽二，Azim Mohammad Anwar-ul，小川数馬，川井恵一, 絹谷清剛, 柴和弘
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 前シナプスコリン作動性神経描画用新規VAChTイメージング剤の開発2012
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、道関美祐、小川数馬、川井恵一、河原　栄、柴　和弘、
- Organizer
  第7回日本分子イメージング学会総会・学術大会
- Place of Presentation
  アクトシティ浜松(浜松市）
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 前シナプスコリン作動性神経描画用新規VAChTイメージング剤の開発2012
- Author(s)
  鵜野いずみ、小阪孝史、三輪大輔、北村陽二、道関美祐、小川数馬、川井恵一、河原栄、柴和弘
- Organizer
  第7回日本分子イメージング学会総会・学術大会
- Place of Presentation
  アクトシティ浜松(浜松市)
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] Vesamicol誘導体を用いた新規VAChTイメージング剤の開発2011
- Author(s)
  小阪孝史,鵜野いずみ,北村陽二,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  筑波市
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] VAChTイメージング用新規プローブの合成とその評価2011
- Author(s)
  鵜野いずみ,小阪孝史,北村陽二,小川数馬,川井恵一,絹谷清剛,柴和弘
- Organizer
  第11回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都市
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23591813
[Presentation] 新規σ-2受容体イメージング剤PIDVの開発研究
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Azim A. M.、黒宮里紗、北村陽二、小川数馬、川井恵一、柴和弘
- Organizer
  第9回日本分子イメージング学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] 新規vesamicol類縁体PIDVのσ-2受容体イメージング剤としての可能性
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、北村陽二、Azim A. M.、小川数馬、川井恵一、柴和弘
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県神戸市）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860987
[Presentation] SPECT用シグマ-2受容体イメージング剤の合成と基礎的評価
- Author(s)
  小阪孝史、緩詰沙耶、三輪大輔、Azim A. M.、黒宮里紗、北村陽二、小川数馬、川井恵一、絹谷清剛、柴和弘
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26860987

1. SHIBA Kazuhiro (40143929)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. KITAMURA Yoji (10368483)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
3. 横山茂 (00210633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKI Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 絹谷清剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 小川数馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Kozaka Takashi 小阪 孝史

KOZAKA Takashi 小阪 孝史

Research Projects

Research Products

Co-Researchers

Development of CNS disease imaging probes targeting sigma-2 receptorsPrincipal Investigator

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Development of Novel Solid Tumor Imaging Agents Targeting the sigma ReceptorPrincipal Investigator

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Development of sigma-1 receptor imaging agent for early diagnosis of stress-related diseases

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Development of a new sigma-2 receptor ligand for imaging and BNCTPrincipal Investigator

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Development of the sigma-2 receptor imaging agent for the purpose of early detection and the proliferation potency diagnosis of the solid tumorPrincipal Investigator

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The development of the presynaptic cholinergic nerve molecules imaging agent for early diagnosis of Alzheimer's disease

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Development of the Colin transporter imaging agent for early diagnosis of Alzheimer's disease

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The imaging study of sigma-1 receptor in the brain for the objective evaluation method of the disease caused by aging or stressPrincipal Investigator

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[Journal Article] 125I-labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (125I-OI5V) imaging visualized augmented sigma-1 receptor expression according to the severity of myocardial ischemia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro and in vivo evaluation of [125/123I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([125/123I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.2021

Author(s)

Journal Title

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[Journal Article] (－)‐o‐[11C]methyl‐trans‐decalinvesamicol ((－)‐[11C]OMDV) as a PET ligand for the vesicular acetylcholine transporter2020

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[Journal Article] Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging2019

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[Journal Article] Development of a novel radiobromine-labeled sigma-1 receptor imaging probe2018

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[Journal Article] In vivo differences between two optical isomers of radioiodinated o-iodo-trans-decalinvesamicol for use as a radioligand for the vesicular acetylcholine transporter.2016

Author(s)

Kozaka Takashi 小阪孝史

KOZAKA Takashi 小阪孝史