SHIBATA Keisuke 柴田圭輔

Researcher Number	50580411
Affiliation (based on the past Project Information) *help	2014 – 2017: 山梨大学, 総合研究部, 助教 2011 – 2013: 山梨大学, 医学工学総合研究部, 助教 2010 – 2011: 山梨大学, 大学院・医学工学総合研究部, 助教
Review Section/Research Field	Principal Investigator Pain science / General pharmacology Except Principal Investigator Neurosurgery / Neurochemistry/Neuropharmacology / Biological Sciences
Keywords	Principal Investigator 一次体性感覚野 / 神経障害性疼痛 / アロディニア / グリア性シナプス再編 / 神経回路組み替え / シナプス再編 / ATP / 慢性疼痛 / グリア細胞 / 異常神経回路 … More / グリア細胞機能変調 / グリア性神経回路組み替え / アストロサイト / 生薬 / In vivo イメージング / 生薬・漢方 / 生薬・漢方薬 / in vivo イメージング … More Except Principal Investigator アストロサイト / グリア細胞 / P2受容体 / ATP / ミクログリア / P2X7受容体 / 虚血 / グリア / グリア伝達 / 虚血耐性 / 脳卒中 / トランスポーター / 開口放出 / グリア伝達物質 / 神経細胞障害 / UTP / 炎症 / サイトカイン / 脳傷害 / TNF-α / TGF-β / 傷害 / 貪食センサー / モーダルシフト / ATPセンサー / UDP / 神経細胞傷害 / 貪食 Less

一次体性感覚野シナプス再編の分子機構を解明し操るPrincipal Investigator
- Principal Investigator
  
  柴田圭輔
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  University of Yamanashi
Mechanisms of gilal cell-dependent synapse remodeling in primary somatosensory cortex underlying development of chronic painPrincipal Investigator
- Principal Investigator
  
  SHIBATA Keisuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pain science
- Research Institution
  University of Yamanashi
Mechanisms underlying glia-mediated ischemic tolerance
- Principal Investigator
  
  KOIZUMI Schuichi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
Analysis of therapeutic mechanisms of Bushi by using in vivo imagingPrincipal Investigator
- Principal Investigator
  
  SHIBATA Keisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Yamanashi
Mechanisms underlying gliotransmission-mediated neuronal plasticity
- Principal Investigator
  
  KOIZUMI Schuichi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Yamanashi
Information processing by the interaction of the ATP-sensors and mechano-sensors
- Principal Investigator
  
  KOIZUMI Schuichi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.2017
- Author(s)
  5.Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 1 Pages: e0168234-e0168234
- DOI
  10.1371/journal.pone.0168234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K15524, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-15H04972
[Journal Article] Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation.2017
- Author(s)
  Shinozaki Y, Shibata K, Yoshida K, Shigetomi E, Gachet C, Ikenaka K, Tanaka KF, Koizumi S.
- Journal Title
  
  Cell Rep
  
  Volume: 19 Issue: 6 Pages: 1151-1164
- DOI
  10.1016/j.celrep.2017.04.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-17K09032, KAKENHI-PROJECT-16K18390
[Journal Article] P2Y6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice2017
- Author(s)
  Kira S,Yoshiyama M,Tsuchiya S,Shigetomi E,Miyamoto T,Nakagomi H,Shibata K,Mochizuki T,Takeda M,Koizumi S
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 771-771
- DOI
  10.1038/s41598-017-00824-2
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-17K09032
[Journal Article] The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells2017
- Author(s)
  Ihara Tatsuya、Mitsui Takahiko、Nakamura Yuki、Kanda Mie、Tsuchiya Sachiko、Kira Satoru、Nakagomi Hiroshi、Sawada Norifumi、Hirayama Yuri、Shibata Keisuke、Shigetomi Eiji、Shinozaki Yoichi、Yoshiyama Mitsuharu、Nakao Atsuhito、Takeda Masayuki、Koizumi Schuichi
- Journal Title
  
  Neurourology and Urodynamics
  
  Volume: 37 Issue: 3 Pages: 942-951
- DOI
  10.1002/nau.23400
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11175, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-17K09032, KAKENHI-PROJECT-18K06481, KAKENHI-PROJECT-16K11042
[Journal Article] Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain.2016
- Author(s)
  Kim SK, Hayashi H, Ishikawa T, Shibata K, Shigetomi E, Shinozaki Y, Inada H, Roh SE, Kim SJ, Lee G, Bae H, Moorhouse AJ, Mikoshiba K, Fukazawa Y, Koizumi S, Nabekura J.
- Journal Title
  
  J Clin Invest
  
  Volume: 126(5) Issue: 5 Pages: 1983-1997
- DOI
  10.1172/jci82859
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21604, KAKENHI-PROJECT-26860380, KAKENHI-PLANNED-25117003, KAKENHI-PUBLICLY-15H01281, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-16H04662, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-15K15524
[Journal Article] The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.2016
- Author(s)
  Ihara, T., Mitsui, T., Nakamura, Y., Kira, S., Miyamoto, T., Nakagomi, H., Sawada, N., Hirayama, Y., Shibata, K., Shigetomi, E., Shinozaki, Y., Yoshiyama, M., Nakao, A., *Takeda, M. *Koizumi, S.
- Journal Title
  
  Neurourology and Urodynamics
  
  Volume: 36 Issue: 4 Pages: 1034-1038
- DOI
  10.1002/nau.23062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K11042, KAKENHI-PROJECT-15H04972
[Journal Article] An effective therapeutic approach for oxaliplatin-induced peripheral neuropathy using a combination therapy with goshajinkigan and bushi.2016
- Author(s)
  Mizuno K, Shibata K, Komatsu R, Omiya Y, Kase Y, Koizumi S.
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 17(11) Pages: 1206-1212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860380
[Journal Article] Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase2016
- Author(s)
  Nakagomi H,Yoshiyama M,Mochizuki T,Miyamoto T,Komatsu R,Imura Y,Morizawa Y,Hiasa M,Kira S,Fujishita K,Shibata K,Shigetomi E,Shinozaki Y,Takeda M,Koizumi S
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 29761-29761
- DOI
  10.1038/srep29761
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-26460067, KAKENHI-PROJECT-26461383, KAKENHI-PROJECT-26860380, KAKENHI-PROJECT-16K08230, KAKENHI-PROJECT-16K11042
[Journal Article] ブシ　神経障害性疼痛2015
- Author(s)
  小泉修一、柴田圭輔
- Journal Title
  
  日本精神神経薬理学雑誌
  
  Volume: in　press
- Data Source
  KAKENHI-PROJECT-25670622
[Journal Article] Mechanism underlying ATP release in human epidermal keratinocytes.2014
- Author(s)
  Inoue K, Komatsu R, Imura Y, Fujishita K, Shibata K, Moriyama Y, Koizumi S.
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 134(5) Issue: 5 Pages: 1465-1468
- DOI
  10.1038/jid.2013.516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790287, KAKENHI-PLANNED-25117003, KAKENHI-PROJECT-25253008
[Journal Article] In vitro blood-brain barrier models using brain microvascular endothelial cells isolated from infant and adult rats retain age-related phenotypes in the bariier properties2013
- Author(s)
  Takata, F., Dohgu, S., Yamauchi, A., Matsumoto, J., Machida, T., Fujishita, K., Shibata, K., Shinozaki, Y., Sato, K., Kataoka, Y. and Koizumi, S
- Journal Title
  
  PLoS One
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034
[Journal Article] Microglia release ATP by exocytosis.2013
- Author(s)
  Imura Y, Morizawa Y, Komatsu R, Shibata K, Shinozaki Y, Kasai H, Moriishi K, Moriyama Y, Koizumi S.
- Journal Title
  
  Glia
  
  Volume: 61(8) Issue: 8 Pages: 1320-1330
- DOI
  10.1002/glia.22517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790287, KAKENHI-PUBLICLY-25116512, KAKENHI-PLANNED-25117003
[Journal Article] Cell-autonomous enhancement of glutamate-uptake by female astrocytes2012
- Author(s)
  Morizawa, Y., Sato, K., Takaki, J., Kawasaki, A., Shibata, K., Suzuki, T., Ohta, S. and Koizumi, S
- Journal Title
  
  Cell. Mol. Neurobiol
  
  Volume: 32 Pages: 953-956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034
[Journal Article] The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice2011
- Author(s)
  Keisuke Shibata, Takeshi Sugawara T, Kayoko Fujishita, Youichi Shinozaki, Takashi Matsukawa, Tsutomu Suzuki, Schuichi Koizumi
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790287
[Journal Article] 難治性神経障害性疼痛における生薬ブシ末の鎮痛効果2011
- Author(s)
  Shibata K
- Journal Title
  
  ペインクリニック
  
  Volume: 32 Pages: 1481-1490
- Data Source
  KAKENHI-PROJECT-23790287
[Journal Article] The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice.2011
- Author(s)
  Shibata K
- Journal Title
  
  PLoS One
  
  Volume: 6(8) Issue: 8 Pages: e23510-e23510
- DOI
  10.1371/journal.pone.0023510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790287
[Journal Article] The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice2011
- Author(s)
  Shibata, K., Sugawara, T., Fujishita, K., Shinozaki, Y., Matsukawa, T., Suzuki, T. and Koizumi, S
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034
[Journal Article] Grape seed extract (GSE) acting on astrocytes, reveals its neuronal protection against oxidative stress via interleukin-6-mediated mechanisms.2009
- Author(s)
  Fujishita, K., Ozawa, T., Shibata, K., Tanabe, S., Sato, Y., Hisamoto, M., Okuda, T., Koizumi, S.
- Journal Title
  
  Cell Mol Neurobiol. 29
  
  Pages: 1121-1129
- Data Source
  KAKENHI-PLANNED-18077011
[Journal Article] Grape seed extract (GSE) acting on astrocytes, reveals its neuronal protection against oxidative stress via interleukin-6-mediated mechanisms
- Author(s)
  Fujishita, K., Ozawa, T., Shibata, K., Tanabe, S., Sato, Y, Hisamoto, M., Okuda, T. and Koizumi, S.
- Journal Title
  
  Cell Mol Neurobiol (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077011
[Journal Article] Microglia release ATP by exocytosis
- Author(s)
  Imura, Y., Morizawa, Y., Komatsu, R., Shibata, K., Shinozaki, Y., Moriyama, Y. and Koizumi S
- Journal Title
  
  Glia
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240034
[Journal Article] Grape seed extract (GSE) acting on astrocytes, reveals its neuronal protection against oxidative stress via interleukin-6-mediated mechanisms.
- Author(s)
  Fujishita, K., Ozawa, T., Shibata, K., Tanabe, S., Sato, Y., Hisamoto, M., Okuda, T. and Koizumi, S.
- Journal Title
  
  Cell Mol Neurobiol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077011
[Patent] グリア細胞の活性化抑制組成物2012
- Inventor(s)
  小泉修一、松川隆、藤下加代子、菅原健、柴田圭輔
- Industrial Property Rights Holder
  国立大学法人山梨大学
- Industrial Property Number
  2009-267902
- Filing Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-21240034
[Patent] 神経細胞の維持や修復に有用な薬剤2009
- Inventor(s)
  小泉修一(山梨大学)、柴田圭輔(山梨大学)、小澤哲朗(山梨大学)、柴田圭輔(山梨大学)、松川隆(山梨大学)
- Industrial Property Rights Holder
  小泉修一(山梨大学)、柴田圭輔(山梨大学)、小澤哲朗(山梨大学)、柴田圭輔(山梨大学)、松川隆(山梨大学)
- Industrial Property Number
  2009-183294
- Filing Date
  2009-08-06
- Data Source
  KAKENHI-PLANNED-18077011
[Patent] グリア細胞の活性化抑制組成物2009
- Inventor(s)
  小泉修一(山梨大学)、柴田圭輔(山梨大学)、藤下加代子(山梨大学)、菅原健(山梨大学)、松川隆(山梨大学)
- Industrial Property Rights Holder
  小泉修一(山梨大学)、柴田圭輔(山梨大学)、藤下加代子(山梨大学)、菅原健(山梨大学)、松川隆(山梨大学)
- Industrial Property Number
  2009-267902
- Filing Date
  2009-11-25
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] 大脳皮質体性感覚野のグリア性神経回路組み替えによる末梢感覚情報の変化-プリンシグナリングの関与-2017
- Author(s)
  柴田圭輔、久保田啓太、小泉修一
- Organizer
  CREST合同ミーティング
- Place of Presentation
  勝沼ぶどうの丘センター（山梨、甲州市）
- Year and Date
  2017-02-07
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] 一次体性感覚野におけるATPを介したアストロサイト性シナプス再編の分子メカニズム2017
- Author(s)
  久保田啓太、柴田圭輔、江藤圭、稲田浩之、篠崎陽一、繁冨英治、御子柴克彦、鍋倉淳一、小泉修一
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎パブリックホール、長崎新聞文化ホールアストピア（長崎、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] 一次体性感覚野のATP増加がアストロサイト性シナプス再編及び機械的アロディニアを引き起こす2017
- Author(s)
  柴田圭輔、久保田啓太、石川達也、篠崎陽一、繁冨英治、御子柴克彦、鍋倉淳一、小泉修一
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎パブリックホール、長崎新聞文化ホールアストピア（長崎、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] 慢性疼痛形成時の一次体性感覚野におけるATPの役割2016
- Author(s)
  柴田圭輔、久保田啓太、石川達也、鍋倉淳一、小泉修一
- Organizer
  第20回Japan　Purine　Club　Meeting
- Place of Presentation
  東京慈恵会医科大学 (東京、港区)
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] グリア細胞とシナプInhibition by Goshajinkigan, a traditional Japanese medicine, of paclitaxel-induced peripheral neuropathy via astrocytesスの近接場光学顕微鏡観察2016
- Author(s)
  Kenta Takanashi, Keisuke Shibata, Keita Kubota, Keita Mizuno, Yuji Omiya, Yoshio Kase, Schuichi Koizumi
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] グリア細胞とシナプスの近接場光学顕微鏡観察2016
- Author(s)
  酒井優、岡部菜央、櫻井杏梨、篠崎陽一、柴田圭輔、繁冨英治、小泉修一、内山和治、堀裕和、小林潔
- Organizer
  日本光学会ナノオプティクス研究グループ第22回研究討論会
- Place of Presentation
  東京農工大学科学博物館本館（東京都小金井市）
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] 牛車腎気丸の抗癌剤誘発ニューロパチー抑制作用2016
- Author(s)
  高梨健太、柴田圭輔、水野景太、大宮雄司、小泉修一
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋大学医学部医系研究棟1号館地下会議室（愛知、名古屋市）
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] アストロサイトのプリン作動性シグナルによる一次体性感覚野における神経ネットワーク制御2016
- Author(s)
  久保田啓太、柴田圭輔、江藤圭、稲田浩之、石川達也、高梨健太、繁冨英治、篠崎陽一、鍋倉淳一、小泉修一
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] ブシ末による慢性疼痛のグリア性制御2016
- Author(s)
  小泉修一、柴田圭輔
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国、ソウル
- Year and Date
  2016-07-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860380
[Presentation] Formation of synapses in somatosensory cortex of developing mice: using in vivo two photon imaging2014
- Author(s)
  Akiko Miyamoto1,2, Kei Eto2, Hideji Murakoshi3, Keisuke Shibata4, Shuichi Koizumi4, Junichi Nabekura1,2
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島）
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] 神経障害性疼痛におけるグリア細胞の役割と生薬ブシ末の鎮痛メカニズム2012
- Author(s)
  柴田圭輔
- Organizer
  日本東洋医学会関東甲信越支部山梨県部会
- Place of Presentation
  山梨県(招待講演)
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21240034
[Presentation] 神経障害性疹痛におけるグリア細胞の役割と生薬ブシ末の鎮痛メカニズム2012
- Author(s)
  柴田圭輔
- Organizer
  日本東洋医学会関東甲信越支部山梨県部会
- Place of Presentation
  山梨玉穂ふれあい診療所(口頭発表)
- Year and Date
  2012-01-28
- Invited
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] 小泉修一生薬ブシ末は活性化アストロサイトを抑制図2.受容体Xのアゴニストを処置したときのS1アストロサイトのCa2+応答して慢性化した神経障害性疹痛を緩解する2012
- Author(s)
  柴田圭輔、菅原健、藤下加代子、篠崎陽一、鈴木勉
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  山梨ベルクラシック甲府
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] 神経障害性疼痛におけるグリア細胞の役割と生薬ブシ末の鎮痛メカニズム2012
- Author(s)
  柴田圭輔
- Organizer
  日本東洋医学会関東甲信越支部山梨県部会(招待講演)
- Place of Presentation
  どちペインクリニック（山梨県）
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] 生薬ブシによるアストロサイトを標的とした神経障害性疼痛治療2011
- Author(s)
  柴田圭輔
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] The astrocytes-targeted therapy by Bushi for the neuropathic pain in mice.2011
- Author(s)
  Shibata K
- Organizer
  Neuroscience 2011
- Place of Presentation
  Walter E. Washington Convention Center（アメリカ）
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] The astrocyte-targeted therapy by Bushi for the neuropathic pain2011
- Author(s)
  Keisuke Shibata, Takeshi Sugawara, Kayoko Fujishita, Youichi Shinozaki, Takashi Matsukawa, Tsutomu Suzuki and Schuichi Koizumi
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシブィコ横浜(Oral presentation)
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice2011
- Author(s)
  Shibata, K.
- Organizer
  Society for Neuroscience Meeting
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PROJECT-21240034
[Presentation] The astrocyte-targeted therapy by Bushi for the neuropathic pain2011
- Author(s)
  柴田圭輔
- Organizer
  第34回日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21240034
[Presentation] The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice2011
- Author(s)
  Keisuke Shibata, Takeshi Sugawara, Kayoko Fujishita, Youichi Shinozaki, Takashi Matsukawa, Tsutomu Suzuki and Schuichi Koizumi
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington D.C
- Data Source
  KAKENHI-PROJECT-23790287
[Presentation] The pathology of neuropathic pain characterized by mechanisms of analgesic effect of Bushimatsu.2010
- Author(s)
  Shibata K
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21240034
[Presentation] The pathology of neuropathic pain characterized by mechanisms of analgesic effect of Bushimatsu.2010
- Author(s)
  Shibata K
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Antidepressants increase BDNF in astrocytes.2009
- Author(s)
  Ozawa, T., Fujishita, K., Shibata, K and Koizumi, S.
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Contribution of astrocytes to the "French paradox" in the CNS.2009
- Author(s)
  Koizumi, S., Fujishita, K., Shibata, K., Ozawa, T., Tanabe, S., Sato, Y.
- Place of Presentation
  Paris, France.
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Cell-to-cell communication mediated by extracellular nucleotides in the CNS.2009
- Author(s)
  柴田圭輔
- Organizer
  A lecture in commemoration of receiving prize "Japan Academy Medal" Fukuoka Purine 2009
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Analgesic effect of Bushimatsu on neuropathic pain2009
- Author(s)
  Shibata, K., Sugawara, K., Fujishita, K. Ozawa, T. Matsukawa, T., Suzuki, T. and Koizumi. S.
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] 神経因性疼痛へのブシ末の鎮痛効果2009
- Author(s)
  柴田圭輔
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保
- Data Source
  KAKENHI-PROJECT-21240034
[Presentation] Analgesic effect of Bushimatsu on neuropathic pain.2009
- Author(s)
  Shibata, K., Sugawara, K., Fujishita, K. Ozawa, T. Matsukawa, T., Suzuki, T. and Koizumi, S.
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Contribution of astrocytes to the "French paradox" in the CNS.2009
- Author(s)
  Koizumi, S., Fujishita, K., Shibata, K., Ozawa, T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago, USA.
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] Antidepressants increase BDNF in astrocytes2009
- Author(s)
  Ozawa, T., Fujishita, K., Shibata, K and Koizumi. S.
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-18077011
[Presentation] 生薬ブシ末は活性化アストロサイトを抑制して慢性化した神経障害性疼痛を緩解する
- Author(s)
  柴田圭輔
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  ベルクラシック甲府（甲府市）
- Data Source
  KAKENHI-PROJECT-23790287

1. KOIZUMI Schuichi (10280752)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. FUJISHITA Kayoko (10443102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. SHINOZAKI Youichi (10443772)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. SHIGETOMI Eiji (00631061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. OKUBO Satoko (20274954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIYAMA Yoshinori (10150658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KATAOKA Yasufumi (70136513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. KINOUCHI Hiroyuki (30241623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAMURA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. YOSHIYAMA Mitsuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. KIRA Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 中尾篤人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 石川達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 田中謙二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 武田正之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 三井貴彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIBATA Keisuke 柴田 圭輔

Research Projects

Research Products

Co-Researchers

一次体性感覚野シナプス再編の分子機構を解明し操るPrincipal Investigator

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Mechanisms of gilal cell-dependent synapse remodeling in primary somatosensory cortex underlying development of chronic painPrincipal Investigator

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Mechanisms underlying glia-mediated ischemic tolerance

Principal Investigator

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Analysis of therapeutic mechanisms of Bushi by using in vivo imagingPrincipal Investigator

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Mechanisms underlying gliotransmission-mediated neuronal plasticity

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Information processing by the interaction of the ATP-sensors and mechano-sensors

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[Journal Article] Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.2017

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[Journal Article] Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation.2017

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[Journal Article] P2Y6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice2017

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[Journal Article] The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells2017

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[Journal Article] Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain.2016

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[Journal Article] The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.2016

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[Journal Article] An effective therapeutic approach for oxaliplatin-induced peripheral neuropathy using a combination therapy with goshajinkigan and bushi.2016

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[Journal Article] Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase2016

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[Journal Article] ブシ 神経障害性疼痛2015

SHIBATA Keisuke 柴田圭輔

[Journal Article] ブシ　神経障害性疼痛2015