Kato Yuko 加藤優子

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KATO Yuko 加藤優子

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Researcher Number	50580875
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 教授 2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 大分大学, 医学部, 教授 2020 – 2021: 東京医科大学, 医学部, 講師 2018 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2017: 東京医科歯科大学, 大学院保健衛生学研究科, 助教 2015: 東京医科歯科大学, 保健衛生学研究科, 助教 2012 – 2014: 東京医科歯科大学, 大学院保健衛生学研究科, 助教
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 血管平滑筋細胞 / 血管内膜肥厚 / Epac1 / 細胞老化 / 粥状動脈硬化 / 高圧力環境 / 肺動脈性肺高血圧 / 肺動脈性高血圧症 / Stanniocalcin1 / 肺動脈平滑筋細胞 … More / 低酸素誘発性肺高血圧モデル / Stanniocalcin 1 / 肺動脈性肺高血圧症 / 骨髄由来前駆細胞 / 骨髄由来細胞 / 自己抗体 Less

粥状動脈硬化を標的とした「血管平滑筋細胞老化マーカー」の同定Principal Investigator
- Principal Investigator
  
  加藤優子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Oita University
高圧力環境と炎症に着目した肺動脈性肺高血圧症の病態解明とバイオマーカー探索Principal Investigator
- Principal Investigator
  
  加藤優子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
  Tokyo Medical University
Elucidation of the mechanism of promotion of vascular intimal thickening by bone marrow-derived cells using Epac1-deficient micePrincipal Investigator
- Principal Investigator
  
  Kato Yuko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical University
  Tokyo Medical and Dental University
Autoantibodies in connective tissue disease with pulmonary hypertension possibly play a role in the pathogenesis.Principal Investigator
- Principal Investigator
  
  Kato Yuko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Epac1 promotes neointimal thickening via calcium/calcineurin-dependent smooth muscle cell polarization and migration after vascular injury.Principal Investigator
- Principal Investigator
  
  KATO Yuko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University

All 2023 2021 2020 2019 2018 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Transcriptome Analysis Reveals Differential Gene Expression between the Closing Ductus Arteriosus and the Patent Ductus Arteriosus in Humans2021
- Author(s)
  Saito Junichi、Kojima Tomoyuki、Tanifuji Shota、Kato Yuko、Oka Sayuki、Ichikawa Yasuhiro、Miyagi Etsuko、Tachibana Tsuyoshi、Asou Toshihide、Yokoyama Utako
- Journal Title
  
  Journal of Cardiovascular Development and Disease
  
  Volume: 8 Issue: 4 Pages: 45-45
- DOI
  10.3390/jcdd8040045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08976, KAKENHI-PROJECT-20H03650, KAKENHI-PROJECT-20K21638
[Journal Article] Anti-enolase１antibodies from a patient with systemic lupus erythematosus accompanied by pulmonary arterial hypertension promote migration of pulmonary artery smooth muscle cells2020
- Author(s)
  Kato Y.、Kasama T.、Soejima M.、Kubota T.
- Journal Title
  
  Immunology Letters
  
  Volume: 218 Pages: 22-29
- DOI
  10.1016/j.imlet.2019.12.005
- Data Source
  KAKENHI-PROJECT-17K08976
[Journal Article] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration2019
- Author(s)
  Yuko Kato, Utako Yokoyama, Takayuki Fujita, Masanari Umemura, Tetsuo Kubota, Yoshihiro Ishikawa
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 69 Issue: 2 Pages: 175-184
- DOI
  10.1007/s12576-018-0631-7
- NAID
  40021818894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08976, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-18KT0073
[Journal Article] 膠原病患者における肺動脈平滑筋細胞の増殖を促進する自己抗体の検出2015
- Author(s)
  石毛里奈、加藤優子、芝田和弥、笹本健太、窪田哲朗
- Journal Title
  
  臨床検査学教育
  
  Volume: 7 Pages: 80-81
- Data Source
  KAKENHI-PROJECT-26860362
[Journal Article] Inhibition of EP4 signaling attelluates aortic aneurysm formation2012
- Author(s)
  Yokoyama U
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 5 Pages: e36724-e36724
- DOI
  10.1371/journal.pone.0036724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10F00429, KAKENHI-PROJECT-11F01418, KAKENHI-PROJECT-21590936, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-23591087, KAKENHI-PROJECT-23791233, KAKENHI-PROJECT-24390017, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24659100, KAKENHI-PROJECT-24659640, KAKENHI-PROJECT-24790558, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116003, KAKENHI-PUBLICLY-23116514, KAKENHI-PUBLICLY-23136516
[Presentation] 肺動脈性肺高血圧症における疾患特異的圧力感受性分子Stanniocalcin1の役割2023
- Author(s)
  小神真梨子, 加藤優子, 伊藤智子, 中村一文, 阿部信二, 横山詩子
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07352
[Presentation] 肺動脈性肺高血圧症におけるStanniocalcin 1遺伝子の役割2023
- Author(s)
  小神真梨子, 加藤優子, 伊藤智子, 中村一文, 阿部信二, 横山詩子
- Organizer
  第26回東京呼吸病態研究会
- Data Source
  KAKENHI-PROJECT-21K07352
[Presentation] Fibulin-1 promotes intimal thickening after vascular injury in mice2021
- Author(s)
  Yuko Kato, Shota Tanifuji, Utako Yokoyama
- Organizer
  第53回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08976
[Presentation] PGE2-EP4-induced fibulin-1 expression promotes intimal thickening after vascular injury2021
- Author(s)
  Yuko Kato, Shota Tanifuji, Yuki Okumura, Kiku Shimizu, Utako Yokoyama
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08976
[Presentation] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration.2020
- Author(s)
  Kato Y, Yokoyama U, Fujita T, Umemura M, Kubota T, Ishikawa Y.
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08976
[Presentation] Epac1 deficiency inhibits bFGF-induced neointimal formation via diminished phosphorylation of GSK3β2018
- Author(s)
  Yuko Kato, Utako Yokoyama, Takayuki Fujita, Tetsuo Kubota, Yoshihiro Ishikawa
- Organizer
  The 95th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-17K08976
[Presentation] The role of Epac1 in the regulatory mechanisms of vascular smooth muscle cell migration and neointimal formation.2016
- Author(s)
  Yuko Kato, Utako Yokoyama, Yoshihiro Ishikawa.
- Organizer
  The 93th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26860362
[Presentation] Anti-enolase 1 autoantibodies in SLE with pulmonary hypertension induce migration of pulmonary artery smooth muscle cells.2016
- Author(s)
  Yuko Kato, Kazuya Shibata, Rina Ishige, Tetsuo Kubota.
- Organizer
  Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26860362
[Presentation] Epac1 promotes smooth muscle cell migration via calcium/calcineurin-dependent cell polarization.2013
- Author(s)
  Yuko Kato Utako Yokoyama, Satoshi Okumura, Susumu Minamisawa, Yoshihiro Ishikawa
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790558
[Presentation] Epac1 promotes smooth muscle cell migration via calcium/calcineurin-dependent cell polarization2013
- Author(s)
  Kato Y, Yokoyama U, Okumura S, Minamisawa S, Ishikawa S
- Organizer
  The 90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24790558
[Presentation] 膠原病患者における肺動脈平滑筋細胞の増殖を促進する自己抗体の検出
- Author(s)
  石毛里奈、加藤優子、芝田和弥、笹本健太、窪田哲朗
- Organizer
  第９回日本臨床検査学教育学会学術集会
- Place of Presentation
  東京　大田区産業プラザ
- Year and Date
  2014-08-20 – 2014-08-22
- Data Source
  KAKENHI-PROJECT-26860362

1. 横山詩子 (70404994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 中村一文 (10335630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 穴井博文 (20291544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮本伸二 (70253797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 白石裕士 (80452837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kato Yuko 加藤 優子

KATO Yuko 加藤 優子

Research Projects

Research Products

Co-Researchers

粥状動脈硬化を標的とした「血管平滑筋細胞老化マーカー」の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高圧力環境と炎症に着目した肺動脈性肺高血圧症の病態解明とバイオマーカー探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of promotion of vascular intimal thickening by bone marrow-derived cells using Epac1-deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Autoantibodies in connective tissue disease with pulmonary hypertension possibly play a role in the pathogenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epac1 promotes neointimal thickening via calcium/calcineurin-dependent smooth muscle cell polarization and migration after vascular injury.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Transcriptome Analysis Reveals Differential Gene Expression between the Closing Ductus Arteriosus and the Patent Ductus Arteriosus in Humans2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-enolase１antibodies from a patient with systemic lupus erythematosus accompanied by pulmonary arterial hypertension promote migration of pulmonary artery smooth muscle cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 膠原病患者における肺動脈平滑筋細胞の増殖を促進する自己抗体の検出2015

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of EP4 signaling attelluates aortic aneurysm formation2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肺動脈性肺高血圧症における疾患特異的圧力感受性分子Stanniocalcin1の役割2023

Author(s)

Organizer

Data Source

[Presentation] 肺動脈性肺高血圧症におけるStanniocalcin 1遺伝子の役割2023

Author(s)

Organizer

Data Source

[Presentation] Fibulin-1 promotes intimal thickening after vascular injury in mice2021

Author(s)

Organizer

Data Source

[Presentation] PGE2-EP4-induced fibulin-1 expression promotes intimal thickening after vascular injury2021

Author(s)

Organizer

Data Source

[Presentation] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration.2020

Author(s)

Organizer

Data Source

Kato Yuko 加藤優子

KATO Yuko 加藤優子