ABE Jun 阿部淳

Researcher Number	50581831
Affiliation (based on the past Project Information) *help	2012 – 2014: 東京大学, 医学(系)研究科(研究院), 助教 2010 – 2012: 東京大学, 大学院・医学系研究科, 助教 2011: 東京大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Immunology Except Principal Investigator Tumor immunology / Immunology
Keywords	Principal Investigator 抗体産生 / リモデリング / 間質ネットワーク / ゲノムワイド遺伝子発現解析 / CD4陽性ヘルパーT細胞 / 間質細胞ネットワーク / リンパ節 / 獲得免疫 Except Principal Investigator 免疫治療 / DC … More / 骨髄性抑制細胞 / 細胞傷害性T細胞 / 癌性腹膜炎 / 胃がん / 細胞周期 / IFN-γ / スニチニブ / MDSC / γδT細胞 / 樹状細胞 / がん免疫 / 抗腫瘍免疫応答 / γδ T細胞 / PD-1 / 免疫抑制 / CTL / 老化 / メモリーCTL / 免疫記憶 / 免疫学 / 感染症 / 遺伝子 Less

Reverse Translational Research for Understanding immune response in the Tumor and Identification of Biomarkers
- Principal Investigator
  
  KAKIMI KAZUHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor immunology
- Research Institution
  The University of Tokyo
Analysis of the mechanism for the regulation of antibody responses by inflammation-associated remodeling of lymph nodesPrincipal Investigator
- Principal Investigator
  
  ABE Jun
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Elucidation of the molecular bases of the generation and maintenance of CTL memory by next generation DNA sequencer
- Principal Investigator
  
  MATSUSHIMA Kouji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo

All 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Cytotoxic T lymphocytes block tumor growth both by lytic activity and IFN-γ-dependent cell cycle arrest.2015
- Author(s)
  Matsushita H, Hosoi A, Ueha S, Abe J, Fujieda N, Tomura M, Maekawa R, Matsushima K, Ohara O, Kakimi K.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 3 Issue: 1 Pages: 26-36
- DOI
  10.1158/2326-6066.cir-14-0098
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-24501329, KAKENHI-PUBLICLY-25113711, KAKENHI-PROJECT-25460491
[Journal Article] Adoptive cytotoxic T lymphocyte therapy triggers a counter-regulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells.2014
- Author(s)
  Hosoi A, Matsushita H, Shimizu K, Fujii SI, Ueha S, Abe J, Kurachi M, Maekawa R, Matsushima K, Kakimi K.
- Journal Title
  
  Int J Cancer.
  
  Volume: 134 Issue: 8 Pages: 1810-22
- DOI
  10.1002/ijc.28506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-24390326, KAKENHI-PROJECT-24501329, KAKENHI-PROJECT-24659625, KAKENHI-PROJECT-25430148, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-25462014, KAKENHI-PROJECT-26460583
[Journal Article] Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells2013
- Author(s)
  Hashimoto S, Ogoshi K, Sasaki A, Abe J, Qu W, Nakatani Y, Ahsan B, Oshima K, Shand FH, Ametani A, Suzuki Y, Kaneko S, Wada T, Hattori M, Sugano S,Morishita S, Matsushima K
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 8 Pages: 4076-4091
- DOI
  10.4049/jimmunol.1202267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23241058, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25670269, KAKENHI-PLANNED-22129008
[Journal Article] Coordinated changes in DNA methylation in antigen-specific memory CD4 T cells.2013
- Author(s)
  Abe J
- Journal Title
  
  J.Immunol.
  
  Volume: 190(8) Pages: 4076-4091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790525
[Journal Article] B cells regulate antibody responses through the medullary remodeling of inflamed lymph nodes2012
- Author(s)
  Jun Abe, Satoshi Ueha, Hiroyuki Yoneyama, Yusuke Shono, Makoto Kurachi, Akiteru Goto, Masashi Fukayama, Michio Tomura, Kazuhiro Kakimi, and Kouji Matsushima
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 1 Pages: 17-27
- DOI
  10.1093/intimm/dxr089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790525, KAKENHI-ORGANIZER-24111001
[Journal Article] B cells regulate antibody responses through the medullary remodeling of inflamed lymph nodes. Int.2012
- Author(s)
  Abe J
- Journal Title
  
  Immunol.
  
  Volume: 24(1) Pages: 17-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790525
[Journal Article] Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration2011
- Author(s)
  Kurachi Makoto
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 208 Issue: 8 Pages: 1605-1620
- DOI
  10.1084/jem.20102101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05757, KAKENHI-PLANNED-19059004, KAKENHI-PROJECT-21390340, KAKENHI-PROJECT-22300332, KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-22790453
[Journal Article] Chemokine receptor CXCR3 facilitates CD8+ T cell differentiation into short-lived effector cells leading to memory degeneration.2011
- Author(s)
  Abe J
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208(8) Pages: 1605-1620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790525
[Presentation] B cells regulate antibody responses through the medullary remodeling of antigen-draining lymph nodes2013
- Author(s)
  Abe J
- Organizer
  Keystone Symposia B Cell Development and Function
- Place of Presentation
  KeystoneResort, USA
- Year and Date
  2013-02-11
- Data Source
  KAKENHI-PROJECT-23790525
[Presentation] Killing and IFN-γ-dependent G1 cell cycle arrest is the mechanism of regulation of tumor growth by Cytotoxic T Lymphocytes.2013
- Author(s)
  Hirokazu Matsushita, Akihiro Hosoi, Satoshi Ueha, Jun Abe, Michio Tomura, Ryuji Maekawa, Osamu Ohara, Kazuhiro Kakimi.
- Organizer
  21st Annual cancer research Institute International cancer
- Place of Presentation
  NY, USA (The Grand Hyatt in New York City)
- Data Source
  KAKENHI-PROJECT-24501329
[Presentation] Adoptive cytotoxic T lymphocyte therapy triggers a counterregulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells2013
- Author(s)
  Hosoi Akihiro, Matsushita Hirokazu, Shimizu Kanako, Fujii Shin-ichiro, Ueha Satoshi, Abe Jun, Maekawa Ryuji, Matsushima Kouji, Kakimi Kazuhiro
- Organizer
  第42回日本免疫学会総会/学術集会
- Place of Presentation
  千葉県千葉市（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-24501329
[Presentation] CTL therapy regulates tumor growth by IFN-g-dependent cell cycle arrest2012
- Author(s)
  Matsuhsia Hirokazu, Hosoi Akihiro, Ueha Satoshi, Abe Jun, Tomura Michio, Maekawa Ryuji, Ohara Osamu, Kakimi Kazuhiro
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24501329
[Presentation] Cognate and non-cognate B cells mediate the remodeling of lymph node medulla that contributes toantibody responses2011
- Author(s)
  Abe J
- Organizer
  40th Annual Meeting of Japanese Society of Immunology.
- Place of Presentation
  幕張
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790525
[Presentation] Cognate and non-cognate B cells mediate the remodeling of lymph node medulla that contributes to antibody responses2011
- Author(s)
  Jun Abe, Satoshi Ueha, Yusuke Shono, Makoto Kurachi, Michio Tomura, Kazuhiro Kakimi, and Kouji Matsushima
- Organizer
  日本免疫学会
- Place of Presentation
  幕張国際会議場　（千葉県　幕張市）
- Data Source
  KAKENHI-PROJECT-23790525
[Presentation] B cells regulate antibody responses through the medullary remodeling of antigen-draining lymph nodes
- Author(s)
  Jun Abe, Satoshi Ueha, Hiroyuki Yoneyama, Yusuke Shono, Makoto Kurachi, Akiteru Goto, Masashi Fukayama, Michio Tomura, Kazuhiro Kakimi, Kouji Matsushima
- Organizer
  Keystone Symposia "B Cell Development and Function"
- Place of Presentation
  Keystone Resort (米国)
- Data Source
  KAKENHI-PROJECT-23790525

1. UEHA Satoshi (00447385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. MATSUSHIMA Kouji (50222427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. HASHIMOTO Shinichi (00313099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. KURACHI Makoto (00396722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAKIMI KAZUHIRO (80273358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. MATSUSHITA Hirokazu (80597782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. FUJII Shinーichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 清水佳奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ABE Jun 阿部 淳

Research Projects

Research Products

Co-Researchers

Reverse Translational Research for Understanding immune response in the Tumor and Identification of Biomarkers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism for the regulation of antibody responses by inflammation-associated remodeling of lymph nodesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular bases of the generation and maintenance of CTL memory by next generation DNA sequencer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cytotoxic T lymphocytes block tumor growth both by lytic activity and IFN-γ-dependent cell cycle arrest.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adoptive cytotoxic T lymphocyte therapy triggers a counter-regulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coordinated changes in DNA methylation in antigen-specific memory CD4 T cells.2013

Author(s)

Journal Title

Data Source

[Journal Article] B cells regulate antibody responses through the medullary remodeling of inflamed lymph nodes2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] B cells regulate antibody responses through the medullary remodeling of inflamed lymph nodes. Int.2012

Author(s)

Journal Title

Data Source

[Journal Article] Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemokine receptor CXCR3 facilitates CD8+ T cell differentiation into short-lived effector cells leading to memory degeneration.2011

Author(s)

Journal Title

Data Source

[Presentation] B cells regulate antibody responses through the medullary remodeling of antigen-draining lymph nodes2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Killing and IFN-γ-dependent G1 cell cycle arrest is the mechanism of regulation of tumor growth by Cytotoxic T Lymphocytes.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Adoptive cytotoxic T lymphocyte therapy triggers a counterregulatory immunosuppressive mechanism via recruitment of myeloid-derived suppressor cells2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] CTL therapy regulates tumor growth by IFN-g-dependent cell cycle arrest2012

Author(s)

Organizer

Place of Presentation

Data Source

ABE Jun 阿部淳