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YAMADA MAYUMI  山田 真弓

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Yamada Mayumi  山田 真弓

山田 真弓  ヤマダ マユミ

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Researcher Number 50583457
Other IDs
Affiliation (Current) 2025: 京都大学, 医生物学研究所, 特定准教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 京都大学, 医生物学研究所, 特定准教授
2021: 京都大学, 生命科学研究科, 講師
2018 – 2020: 京都大学, 生命科学研究科, 特定助教
2016 – 2017: 京都大学, 医学研究科, 特定助教
2015: 京都大学, 医学(系)研究科(研究院), 助教
2011: 独立行政法人国立精神・神経医療研究センター, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 44020:Developmental biology-related / Nerve anatomy/Neuropathology / Neuroscience in general
Keywords
Principal Investigator
神経幹細胞 / 転写因子 / 光遺伝学 / RNAシークエンス / 神経発生 / ニューロン / 細胞増殖 / 遺伝子発現 / ニューロン分化 / 遺伝子発現プロファイル … More / ニューロン新生 / 側脳室周囲 / 海馬歯状回 / 遺伝子発現プロファイリング / 神経新生 / NGS / 光操作技術 / 振動発現 / NGS解析 / bHLH型転写因子 / 光作動性Tetシステム / RNA-seq / Tetシステム / 細胞分化 / 遺伝子ネットワーク / RNAシークエンス解析 / 分化運命決定因子 / RNA-seq解析 / 光操作 / トランスジェニックマウス / 光作動性転写因子 / FACS / 成体脳 Less
  • Research Projects

    (5 results)
  • Research Products

    (34 results)
  • Co-Researchers

    (6 People)
  •  光操作技術とNGS解析を用いた神経幹細胞の制御メカニズムの解析Principal Investigator

    • Principal Investigator
      山田 真弓
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kyoto University
  •  Analysis of neural stem cell regulatory mechanisms using a novel light manipulation systemPrincipal Investigator

    • Principal Investigator
      Yamada Mayumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kyoto University
  •  Finding novel adult neurogenesis-related genes in the mouse brainPrincipal Investigator

    • Principal Investigator
      Yamada Mayumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  Analysis of the temporal gene expression changes in neural stem cells during brain maturation and agingPrincipal Investigator

    • Principal Investigator
      Yamada Mayumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  小脳をモデル系とした、bHLH型転写因子による神経細胞多様性獲得機構の解明Principal Investigator

    • Principal Investigator
      山田 真弓
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      National Center of Neurology and Psychiatry

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

  • [Book] 「細胞」生後脳・成体脳におけるニューロン新生と神経幹細胞の制御機構2018

    • Author(s)
      今吉 格、山田 真弓
    • Total Pages
      4
    • Publisher
      ニュー・サイエンス社
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Book] 「Clinical Neuroscience」遺伝子発現の光制御2018

    • Author(s)
      今吉 格、山田 真弓
    • Total Pages
      4
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Book] Essentials of cerebellum and cerebellar disorders2016

    • Author(s)
      Mayumi Yamada, Mikio Hoshino
    • Total Pages
      5
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Journal Article] Enhancement of Vivid-based photo-activatable Gal4 transcription factor in mammalian cells2023

    • Author(s)
      Nagasaki, S.C., Fukuda, T.D., Yamada, M., Suzuki, Y.I., Kakutani, R., Guy, A.T. and *Imayoshi, I.
    • Journal Title

      Cell Struct. Funct.

      Volume: 48 Issue: 1 Pages: 31-47

    • DOI

      10.1247/csf.22074

    • ISSN
      0386-7196, 1347-3700
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02485, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06884, KAKENHI-PROJECT-23K05792
  • [Journal Article] Functional rejuvenation of aged neural stem cells by Plagl2 and anti-Dyrk1a activity2022

    • Author(s)
      Kaise Takashi、Fukui Masahiro、Sueda Risa、Piao Wenhui、Yamada Mayumi、Kobayashi Taeko、Imayoshi Itaru、Kageyama Ryoichiro
    • Journal Title

      Genes & Development

      Volume: 36 Issue: 1-2 Pages: 23-37

    • DOI

      10.1101/gad.349000.121

    • NAID

      120007185924

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04976, KAKENHI-PROJECT-20J15083, KAKENHI-PROJECT-20K06667
  • [Journal Article] Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter.2022

    • Author(s)
      Oishi M, Stefan P, Yamazaki Y, Unekawa M, Adachi R, Yamada M, Imayoshi I, Abe Y, Steinhauser C, Tanaka KF
    • Journal Title

      Glia

      Volume: 71 Issue: 2 Pages: 317-333

    • DOI

      10.1002/glia.24273

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-22K06467, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-23K05792
  • [Journal Article] Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module2021

    • Author(s)
      Harada Yujin、Yamada Mayumi、Imayoshi Itaru、Kageyama Ryoichiro、Suzuki Yutaka、Kuniya Takaaki、Furutachi Shohei、Kawaguchi Daichi、Gotoh Yukiko
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 6562-6562

    • DOI

      10.1038/s41467-021-26605-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06481, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-21K15180, KAKENHI-PROJECT-16H06279
  • [Journal Article] An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation2021

    • Author(s)
      Inoue Yukiko U.、Morimoto Yuki、Yamada Mayumi、Kaneko Ryosuke、Shimaoka Kazumi、Oki Shinji、Hotta Mayuko、Asami Junko、Koike Eriko、Hori Kei、Hoshino Mikio、Imayoshi Itaru、Inoue Takayoshi
    • Journal Title

      Cells

      Volume: 10 Issue: 5 Pages: 1076-1076

    • DOI

      10.3390/cells10051076

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-16K21734, KAKENHI-PUBLICLY-19H04895, KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K07895, KAKENHI-PROJECT-20H02932
  • [Journal Article] Light-mediated Control of Gene Expression in Mammalian Cells.2020

    • Author(s)
      Yamada M, Nagasaki C. S, Ozawa T, Imayoshi I.
    • Journal Title

      Neuroscience Research

      Volume: 152 Pages: 66-77

    • DOI

      10.1016/j.neures.2019.12.018

    • NAID

      120006888020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K14950, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-18K19092, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06529, KAKENHI-PROJECT-18H02449, KAKENHI-PROJECT-19H00900
  • [Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020

    • Author(s)
      Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 8 Issue: 1 Pages: 206-206

    • DOI

      10.1186/s40478-020-01082-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06886, KAKENHI-PROJECT-18KK0307, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17K07063, KAKENHI-PROJECT-17K07126, KAKENHI-PROJECT-18K07577, KAKENHI-PLANNED-16H06528, KAKENHI-PLANNED-16H06532, KAKENHI-PROJECT-18H02538
  • [Journal Article] Optimization of light-inducible Gal4/UAS gene expression system in mammalian cells2020

    • Author(s)
      Yamada M., Nagasaki C. S., Suzuki Y., Imayoshi I.
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101506-101506

    • DOI

      10.1016/j.isci.2020.101506

    • NAID

      120006884197

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06667, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06529
  • [Journal Article] Enhanced lysosomal degradation maintains the quiescent state of neural stem cells2019

    • Author(s)
      T. Kobayashi, W. Piao, T. Takamura, H. Kori, H. Miyachi, S. Kitano, Y. Iwamoto, M. Yamada, I. Imayoshi, S. Shioda, A. Ballabio, R. Kageyama
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 5446-5446

    • DOI

      10.1038/s41467-019-13203-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-16H06480, KAKENHI-PLANNED-16H06529, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-18H02449, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-17K07409, KAKENHI-PROJECT-17K14950, KAKENHI-INTERNATIONAL-15K21731
  • [Journal Article] Light Control of the Tet Gene Expression System in Mammalian Cells2018

    • Author(s)
      Yamada Mayumi、Suzuki Yusuke、Nagasaki Shinji C.、Okuno Hiroyuki、Imayoshi Itaru
    • Journal Title

      Cell Reports

      Volume: 25 Issue: 2 Pages: 487-500

    • DOI

      10.1016/j.celrep.2018.09.026

    • NAID

      120006531246

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K14950, KAKENHI-PLANNED-16H06529, KAKENHI-PROJECT-15H04258, KAKENHI-PROJECT-18H02449
  • [Patent] 光活性化可能なTet発現制御システム2018

    • Inventor(s)
      今吉格、山田真弓、鈴木裕輔
    • Industrial Property Rights Holder
      今吉格、山田真弓、鈴木裕輔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] 光操作技術を用いた神経幹細胞の制御メカニズムの解明2024

    • Author(s)
      山田真弓
    • Organizer
      第17回神経発生討論会、第20回成体脳のニューロン新生懇談会合同大会
    • Data Source
      KAKENHI-PROJECT-23K05792
  • [Presentation] Analysis of regulatory mechanism of neural stem cells by optical manipulation of bHLH transcription factor expressions2023

    • Author(s)
      Mayumi Yamada
    • Organizer
      The 29th East Asia Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05792
  • [Presentation] 光操作技術とRNA-seq解析を用いた神経幹細胞の制御機構の解明2023

    • Author(s)
      山田真弓、今吉格
    • Organizer
      Neuro2023
    • Data Source
      KAKENHI-PROJECT-23K05792
  • [Presentation] 光操作技術を用いた神経幹細胞の制御メカニズムの解析2022

    • Author(s)
      山田真弓、長崎真治、Seongchun Yang、今吉格
    • Organizer
      Neuro2022
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] 遺伝子発現の光操作技術の開発と応用2022

    • Author(s)
      山田真弓
    • Organizer
      第45回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] 光操作技術とNGS解析を用いた、神経幹細胞の制御メカニズムの解明2022

    • Author(s)
      山田真弓
    • Organizer
      第18回成体脳新生ニューロン懇談会
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] Analysis of neural stem cell regulatory mechanisms using optogenetics2021

    • Author(s)
      Mayumi Yamada, Itaru Imayoshi
    • Organizer
      第16回生命医科学研究所ネットワーク国際シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] 「青色光」による遺伝子スイッチの制御2021

    • Author(s)
      山田真弓
    • Organizer
      バイオインダストリー協会“未来へのバイオ技術”勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] Dynamic transcriptional regulation of neural stem cells by bHLH factors2020

    • Author(s)
      山田真弓
    • Organizer
      第63回日本神経化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06667
  • [Presentation] 神経幹細胞におけるbHLH型転写因子のダイナミックな発現制御機構2019

    • Author(s)
      山田真弓、長崎真治、今吉格
    • Organizer
      Neuro2019(第42回日本神経科学大会)
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] Optimization of the photo-activatable gene expression system in mammalian cells2018

    • Author(s)
      Mayumi Yamada
    • Organizer
      The 17th International Joint Mini-Symposium on Molecular and Cell Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] Novel Optical Tools for Manipulating Gene Expressions in Neural Stem Cells2018

    • Author(s)
      山田真弓
    • Organizer
      第11回神経発生討論会
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Presentation] Optimization of light-inducible gene expression system in mammalian cells2018

    • Author(s)
      Mayumi Yamada
    • Organizer
      第12回神経発生討論会
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] Novel optical tools for manipulating gene expressions in neural stem cells2017

    • Author(s)
      Mayumi Yamada
    • Organizer
      第11回神経発生討論会
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] New Optical Tools for Manipulating Gene Expressions in Neural Stem Cells2017

    • Author(s)
      山田真弓、今吉格
    • Organizer
      第9回光操作研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Presentation] New optical tools for manipulating gene expressions in neural stem cells2017

    • Author(s)
      Mayumi Yamada
    • Organizer
      第9回光操作研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K14950
  • [Presentation] Dynamic regulation of Olig2 expression in oligodendrocyte differentiation2016

    • Author(s)
      Mayumi Yamada
    • Organizer
      International Society for Developmental Neuroscience (ISDN) 2016
    • Place of Presentation
      Juan les Pins, France
    • Year and Date
      2016-05-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Presentation] 生後脳海馬ニューロン新生の異常と発達障害の関与について2016

    • Author(s)
      山田真弓、今吉格
    • Organizer
      Neuro2016
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Presentation] Dynamic regulation of Olig2 expression in oligodendrocyte differentiation2016

    • Author(s)
      Mayumi Yamada
    • Organizer
      ISDN 2016
    • Place of Presentation
      Palais des Congres d’Antibes Juan les Pins, France
    • Year and Date
      2016-05-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18362
  • [Presentation] Dynamic regulation of Olig2 expression in oligodendrocyte differentiation2015

    • Author(s)
      Mayumi Yamada
    • Organizer
      XII European Meeting on Glial Cells in Health and Disease
    • Place of Presentation
      Bilbao, Spain
    • Year and Date
      2015-07-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18362
  • 1.  影山 龍一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  後藤 由季子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  関根 章博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  畝川 美悠紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  星野 幹雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  今吉 格
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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