Usui Fumitake 河西文武

… Alternative Names

河西文武カワニシフミタケ

Kawanishi Fumitake 河西文武

USUI Fumitake 臼井文武

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Researcher Number	50585560
Other IDs
Affiliation (Current)	2025: 富山県立大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 富山県立大学, 工学部, 講師 2017 – 2021: 富山県立大学, 工学部, 講師 2013 – 2017: 自治医科大学, 医学部, 助教 2016: 富山県立大学, 工学部, 研究員 2011 – 2012: 自治医科大学, 医学部, ポスト・ドクター 2010 – 2011: 自治医科大学, 医学部, ポストドクター
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Basic Section 42010:Animal production science-related Except Principal Investigator Cardiovascular medicine / Endocrinology
Keywords	Principal Investigator 自然免疫 / 炎症 / 血栓症 / 自然炎症 / 循環器疾患 / 生薬 / バイオ医薬品 / 始原生殖細胞 / キメラ / ニワトリ … More / 生活習慣病 / 免疫 / 動脈血栓 / 静脈血栓 / マクロファージ / インフラマソーム / 無菌性炎症 / メタボリック症候群 / 循環器 … More Except Principal Investigator タンパク質修飾 / 心血管病 / 炎症反応 / サイトカイン / 糖尿病 / 肥満 / 脂肪 / 炎症 / M2 / マクロファージ / 分化 / 脂肪細胞 / 免疫プロテアソーム / diabetes / inflammation / macrophages / LMP7 / obeisty / immunoproteasome Less

NLRP3インフラマソームを制御する生薬による動脈硬化、大動脈瘤形成の予防効果の解析Principal Investigator
- Principal Investigator
  
  河西文武
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Toyama Prefectural University
Development of a novel biopharmaceutical production method via chicken eggsPrincipal Investigator
- Principal Investigator
  
  Kawanishi Fumitake
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Toyama Prefectural University
Role of adapter molecule ASC independent of inflammasomePrincipal Investigator
- Principal Investigator
  
  Kawanishi Fumitake
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Toyama Prefectural University
Molecular mechanisms underlying inflammasome-mediated cardiovascular disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Analysis of the role of the immunoproteasome in obesity and diabetes
- Principal Investigator
  
  Kimura Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Jichi Medical University
Role of inflammasome in thormbosisPrincipal Investigator
- Principal Investigator
  
  Usui Fumitake
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Role of inflammasomes in atherosclerosis and aortic aneurysmsPrincipal Investigator
- Principal Investigator
  
  USUI Fumitake
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jichi Medical University
Role of NLRP3 inflammasomes in the metabolic syndrome.Principal Investigator
- Principal Investigator
  
  USUI Fumitake
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jichi Medical University

All 2024 2023 2020 2019 2018 2017 2016 2015 2014 2012 2011 Other

All Journal Article Presentation Book Other

[Book] 疾患モデルの作製と利用：脂質代謝異常と関連疾患2015
- Author(s)
  臼井文武、高橋将文
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-15K09146
[Book] 疾患モデルの作製と利用-脂質代謝異常と関連疾患<<下巻>>2015
- Author(s)
  臼井文武、高橋将文章
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24790775
[Journal Article] Isoliquiritigenin inhibits <scp>NLRP3</scp> inflammasome activation with <scp>CAPS</scp> mutations by suppressing caspase‐1 activation and mutated <scp>NLRP3</scp> aggregation2024
- Author(s)
  Usui‐Kawanishi Fumitake、Kani Koudai、Karasawa Tadayoshi、Honda Hiroe、Takayama Nobuyuki、Takahashi Masafumi、Takatsu Kiyoshi、Nagai Yoshinori
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 5 Pages: 423-431
- DOI
  10.1111/gtc.13108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06627, KAKENHI-PROJECT-23K07558
[Journal Article] Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages.2020
- Author(s)
  1)Watanabe S, Usui-Kawanishi F, Karasawa, Kimura H, Kamata R, Inoue, Mise N, Kasahara T, Takahashi M
- Journal Title
  
  J Cell Physiol
  
  Volume: - Issue: 10 Pages: 7554-7566
- DOI
  10.1002/jcp.29659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290
[Journal Article] ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome2020
- Author(s)
  Watanabe Sachiko、Usui-Kawanishi Fumitake、Komada Takanori、Karasawa Tadayoshi、Kamata Ryo、Yamada Naoya、Kimura Hiroaki、Dezaki Katsuya、Ohmori Tsukasa、Takahashi Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 2 Pages: 125-132
- DOI
  10.1016/j.bbrc.2020.07.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K08524, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08370
[Journal Article] Implications of immune-inflammatory responses in smooth muscle dysfunction and disease2019
- Author(s)
  Usui-Kawanishi Fumitake、Takahashi Masafumi、Sakai Hiroyasu、Suto Wataru、Kai Yuki、Chiba Yoshihiko、Hiraishi Keizo、Kurahara Lin Hai、Hori Masatoshi、Inoue Ryuji
- Journal Title
  
  Journal of Smooth Muscle Research
  
  Volume: 55 Issue: 0 Pages: 81-107
- DOI
  10.1540/jsmr.55.81
- NAID
  130007795217
- ISSN
  0916-8737, 1884-8796
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-15H04678
[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018
- Author(s)
  Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 4 Pages: 744-756
- DOI
  10.1161/atvbaha.117.310581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction2017
- Author(s)
  Kobayashi Motoi、Usui-Kawanishi Fumitake、Karasawa Tadayoshi、Kimura Hiroaki、Watanabe Sachiko、Mise Nathan、Kayama Fujio、Kasahara Tadashi、Hasebe Naoyuki、Takahashi Masafumi
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: 176676-176676
- DOI
  10.1371/journal.pone.0176676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K06912, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] ARIH2 ubiquitinates NLRP3 and negatively regulates NLRP3 inflammasome activation in macrophages2017
- Author(s)
  Kawashima Akira、Karasawa Tadayoshi、Tago Kenji、Kimura Hiroaki、Kamata Ryo、Usui-Kawanishi Fumitake、Watanabe Sachiko、Ohta Satoshi、Funakoshi-Tago Megumi、Yanagisawa Ken、Kasahara Tadashi、Suzuki Koichi、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 10 Pages: 3614
- DOI
  10.4049/jimmunol.1700184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K09808, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-17K08641, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] Caspse-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.2016
- Author(s)
  Kimura H, Karasawa T, Usui F, Kawashima A, Endo Y, Kobayashi M, Sadatomo A, Nakamura J, Iwasaki Y, T Yada,Tsutsui H, Kasahara T, Takahashi M.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 311 Issue: 5 Pages: 881-890
- DOI
  10.1152/ajpendo.00174.2016
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 reduces macrophage interleukin-10 production and enhances the susceptibility to doxorubicin-induced cardiotoxicity.2016
- Author(s)
  Kobayashi M, Usui F, Karasawa T, Kawashima A, Kimura H, Mizushina Y, Shirasuna K, Mizukami H, Kasahara T, Hasebe N, Takahashi M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 26489-26489
- DOI
  10.1038/srep26489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy.2015
- Author(s)
  Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 11 Pages: 4281-4292
- DOI
  10.1210/en.2015-1408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-24592482, KAKENHI-PROJECT-26461386
[Journal Article] Letter regarding article “Inhibition of interleukin-1beta decrease aneurysm formation and progression in murine model of thoracic aortic aneurysm”.2015
- Author(s)
  Usui F, Kobayashi M, Takahashi M.
- Journal Title
  
  Circulation
  
  Volume: 131 Issue: 14
- DOI
  10.1161/circulationaha.114.013988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09146
[Journal Article] NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β2015
- Author(s)
  Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 8 Pages: 5065-5077
- DOI
  10.1074/jbc.m114.603217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146
[Journal Article] Oligomerized CARD16 Promotes Caspase-1 Assembly and IL-1β Processing2015
- Author(s)
  Tadayoshi Karasawa, Akira Kawashima, Fumitake Usui, Hiroaki Kimura, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Junji Sagara, Masafumi Takahashi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 5 Issue: 1 Pages: 348-356
- DOI
  10.1016/j.fob.2015.04.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24890217, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] Role of NLRP3 inflammasomes for rhabdomyolysis-induced acute kidney injury.2015
- Author(s)
  Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10901-10901
- DOI
  10.1038/srep10901
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M.
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461386
[Journal Article] ASC in Renal Collecting Duct Epithelial Cells Contributes to Inflammation and Injury after Unilateral Ureteral Obstruction.2014
- Author(s)
  Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi 7.
- Journal Title
  
  The American journal of pathology
  
  Volume: 184 Pages: 1287-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790775
[Journal Article] Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages2014
- Author(s)
  Hara K, Shirasuna K, Usui F, Karasawa T, Mizushina Y, Kimura H, Kawashima A, Ohkuchi A, Matsuyama S, Kimura K, Takahashi M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: 1-17
- DOI
  10.1371/journal.pone.0113974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-26461386
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Issue: 5 Pages: 1-14
- DOI
  10.3109/17435390.2014.956156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146
[Journal Article] Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm2014
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 35 Issue: 1 Pages: 127-136
- DOI
  10.1161/atvbaha.114.303763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26670621
[Journal Article] NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia-Reperfusion Injury Independently of Inflammasomes.2014
- Author(s)
  Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki, Nishimura S, Sagara J, Noda T, IwakuraY, Hiroko Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M.
- Journal Title
  
  J Immunol
  
  Volume: 192(9) Issue: 9 Pages: 4342-4351
- DOI
  10.4049/jimmunol.1302039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26461386
[Journal Article] Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice2012
- Author(s)
  Usui F, Kimura H, Ohshiro T, Tatsumi K, Kawashima A, Nishiyama A, Iwakura Y, Ishibashi S, Takahashi M
- Journal Title
  
  Biochemical andBiophysical Research Communications
  
  Volume: 420 Pages: 72-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890171
[Journal Article] Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.2012
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 425 Issue: 2 Pages: 162-168
- DOI
  10.1016/j.bbrc.2012.07.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24591419, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-24890217, KAKENHI-PUBLICLY-24117709
[Journal Article] Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice2012
- Author(s)
  Usui F, Kimura H, Ohshiro T, Tatsumi K, Kawashima A, Nishiyama A, Iwakura Y, Ishibashi S, Takahashi M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 420 Pages: 72-77
- Data Source
  KAKENHI-PROJECT-22890171
[Journal Article] Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia reperfusion injury.2011
- Author(s)
  Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U.
- Journal Title
  
  Circulation
  
  Volume: 123 Pages: 594-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890171
[Journal Article] Critical role of Th17 cells in inflammation and neovascularization after ischemia2011
- Author(s)
  Hata T, Takahashi M, Hida S, Kawaguchi M, Kashima Y, Usui F, Morimoto H, Nishiyama A, Izawa A, Koyama J, Iwakura Y, Taki S, Ikeda U
- Journal Title
  
  Cardiovasc Res
  
  Volume: 90 Pages: 364-372
- Data Source
  KAKENHI-PROJECT-22890171
[Journal Article] Critical role of Th17 cells in inflammation and neovascularization after ischemia.2011
- Author(s)
  Hata T, Takahashi M, Hida S, Kawaguchi M, Kashima Y, Usui F, Morimoto H, Nishiyama A, Izawa A, Koyama J, Iwakura Y, Taki S, Ikeda U.
- Journal Title
  
  Cardiovasc Res
  
  Volume: Jan11(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890171
[Journal Article] Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia reperfusion injury2011
- Author(s)
  Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U
- Journal Title
  
  Circulation
  
  Volume: 123 Pages: 594-604
- Data Source
  KAKENHI-PROJECT-22890171
[Presentation] 桜皮のNLRP3インフラマソーム抑制効果の評価2023
- Author(s)
  殿下由季、北林蘭、柴田理名、土田奈桜、唐澤直義、高橋将文、河西文武
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K07558
[Presentation] 良姜のNLRP3インフラマソーム抑制効果の評価2023
- Author(s)
  北林蘭、殿下由季、柴田理名、土田奈桜、唐澤直義、高橋将文、河西文武
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K07558
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食誘導型肥満における免疫プロテアソーム（LMP7）の役割．2016
- Author(s)
  木村博昭、唐澤直義、川島晃、臼井文武、笠原忠、鈴木幸一、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食による肥満・メタボリック病態における免疫プロテアソーム欠損の有益な効果2016
- Author(s)
  木村博昭　臼井文武　唐澤直義　川島晃　笠原忠　鈴木幸一　岩崎有作　矢田俊彦　高橋将文
- Organizer
  高脂肪食による肥満・メタボリック病態における免疫プロテアソーム欠損の有益な効果
- Place of Presentation
  京都国際会館（京都）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 飽和脂肪酸によるインフラマソーム活性化機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第48回日本動脈硬化学会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割．2016
- Author(s)
  高橋将文、駒田敬則、臼井文武、唐澤直義、川島晃、木村博昭．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 高脂肪食誘導型肥満における免疫プロテアソーム(LMP7)の役割2016
- Author(s)
  木村博昭　唐澤直義　川島晃　臼井文武　笠原忠　鈴木幸一　高橋将文
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2016
- Author(s)
  高橋将文、駒田敬則、臼井文武、唐澤直義、川島晃、木村博昭
- Organizer
  第3７回日本炎症・再生医学会
- Place of Presentation
  みやこメッセ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] メタボリック病態における免疫プロテアソーム欠損の有益な効果．2016
- Author(s)
  木村博昭、臼井文武、唐澤直義、川島晃、笠原忠、鈴木幸一、岩﨑有作、矢田俊彦、高橋将文．
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  高橋将文、駒田敬則、臼井文武、川島晃、唐澤直義、木村博昭．
- Organizer
  心血管抗加齢研究会2015
- Place of Presentation
  梅田スカイビル（大阪市北区）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 動脈硬化および大動脈瘤形成におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、谷口俊一郎、高橋将文．
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、駒田敬則、唐澤直義、川島晃、木村博昭、武藤重明、長田太助、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂質代謝異常におけるASCの役割2015
- Author(s)
  唐澤直義、木村博昭、臼井文武、川島晃、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂質代謝異常におけるASCの役割2015
- Author(s)
  唐澤直義、木村博昭、臼井文武、川島晃、高橋将文
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 免疫プロテアソーム欠損は高脂肪食による肥満を抑制する2015
- Author(s)
  木村博昭、臼井文武、唐澤直義、川島晃、笠原忠、岩崎有作、矢田俊彦、高橋将文
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、駒田敬則、唐澤直義、川島晃、木村博昭、武藤重明、長田太助、高橋将文
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 腹部大動脈瘤の形成におけるインフラマソームの役割2012
- Author(s)
  臼井文武、木村博昭、白砂孔明、谷口俊一郎、高橋将文.
- Organizer
  日本炎症・再生医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790775
[Presentation] 腹部大動脈瘤の形成におけるインフラマソームの役割の解明2012
- Author(s)
  13. 臼井文武、木村博昭、白砂孔明、谷口俊一郎、高橋将文.
- Organizer
  日本心血管内分泌代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790775
[Presentation] 動脈硬化の形成におけるIL-17の役割2011
- Author(s)
  臼井文武、木村博昭、岩倉洋一郎、高橋将文
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22890171
[Presentation] 動脈硬化形成におけるインフラマーソムの役割2011
- Author(s)
  臼井文武、木村博昭、谷口俊一郎、高橋将文
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22890171
[Presentation] 動脈硬化の形成におけるIL-17の役割2011
- Author(s)
  臼井文武、木村博昭、岩倉洋一郎、高橋将文
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22890171
[Presentation] 動脈硬化形成におけるインフラマソームの役割2011
- Author(s)
  臼井文武、木村博昭、谷口俊一郎、高橋将文
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22890171
[Presentation] カスパーゼ1ホモログ分子CARD16による新規炎症惹起機序の解析
- Author(s)
  唐澤直義、川島晃、臼井文武、木村博昭、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] NLRP3はインフラマソーム非依存的に肝虚血再灌流障害を軽減する
- Author(s)
  高橋将文、井上賢之、白砂孔明、臼井文武、川島晃、木村博昭
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 大動脈瘤形成におけるNLRP3インフラマソームの役割
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、高橋将文
- Organizer
  第46回日本動脈硬化学会総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10 – 2015-07-11
- Data Source
  KAKENHI-PROJECT-24790775
[Presentation] 大動脈瘤形成におけるNLRP3インフラマソームの役割の解明
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26461386
[Presentation] 大動脈瘤形成におけるNLRP3インフラマソームの役割の解明
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、高橋将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄
- Year and Date
  2015-07-01 – 2015-07-03
- Data Source
  KAKENHI-PROJECT-24790775
[]

1. Kimura Hiroaki (70593622)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. TAKAHASHI Masafumi (40296108)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
3. 渡邊幸子 (80770619)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. 唐澤直義 (60631893)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. 白砂孔明 (20552780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 中村隼明 (30613723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HONDA Hiroe

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 肥田重明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 鎌田諒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Usui Fumitake 河西 文武

河西 文武 カワニシ フミタケ

Kawanishi Fumitake 河西 文武

USUI Fumitake 臼井 文武

Research Projects

Research Products

Co-Researchers

NLRP3インフラマソームを制御する生薬による動脈硬化、大動脈瘤形成の予防効果の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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Development of a novel biopharmaceutical production method via chicken eggsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of adapter molecule ASC independent of inflammasomePrincipal Investigator

Principal Investigator

Project Period (FY)

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Molecular mechanisms underlying inflammasome-mediated cardiovascular disease

Principal Investigator

Project Period (FY)

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Research Institution

Analysis of the role of the immunoproteasome in obesity and diabetes

Principal Investigator

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Research Institution

Role of inflammasome in thormbosisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Role of inflammasomes in atherosclerosis and aortic aneurysmsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Role of NLRP3 inflammasomes in the metabolic syndrome.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] 疾患モデルの作製と利用：脂質代謝異常と関連疾患2015

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Publisher

Data Source

[Book] 疾患モデルの作製と利用-脂質代謝異常と関連疾患<<下巻>>2015

Author(s)

Publisher

Data Source

[Journal Article] Isoliquiritigenin inhibits <scp>NLRP3</scp> inflammasome activation with <scp>CAPS</scp> mutations by suppressing caspase‐1 activation and mutated <scp>NLRP3</scp> aggregation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implications of immune-inflammatory responses in smooth muscle dysfunction and disease2019

Author(s)

Usui Fumitake 河西文武

河西文武カワニシフミタケ

Kawanishi Fumitake 河西文武

USUI Fumitake 臼井文武