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Ito Hikaru  伊藤 日加瑠

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伊藤 日加瑠  イトウ ヒカル

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Researcher Number 50587392
Other IDs
Affiliation (Current) 2025: 香川大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2025: 香川大学, 医学部, 准教授
2021 – 2023: 香川大学, 医学部, 准教授
2018 – 2020: 東京医科歯科大学, 統合研究機構, 助教
2017: 広島大学, 医歯薬保健学研究科(医), 助教
2016: 広島大学, 医歯薬保健学研究院(医), 助教
2012: 東京医科歯科大学, 難治疾患研究所, 助教
2011: 東京医科歯科大学, 難治疾患研究所, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 52030:Psychiatry-related / Basic Section 42040:Laboratory animal science-related / Basic Section 46020:Anatomy and histopathology of nervous system-related / Neurology / Neuroscience in general
Except Principal Investigator
Basic Section 42040:Laboratory animal science-related
Keywords
Principal Investigator
神経科学 / モデル動物 / 精神疾患 / モデルマウス / 精神的ストレス / 周産期うつ病 / 実験動物 / ストレス / 周産期 / うつ病 … More / 分化 / 発達障害 / 発生 / 小頭症 / 神経発達障害 / 細胞・組織 / 動物 / 発生・分化 / 移植・再生医療 / 老化 / 再生医学 / キメラ / 骨格筋 / サルコペニア / 筋ジストロフィー / 発生工学 / 胚盤胞胚補完法 / 骨格筋幹細胞 / 再生医療 / 神経病理 / 病態脳 / AAVベクター / 治療 / ポリグルタミン病 / 神経変性疾患 … More
Except Principal Investigator
分娩 / Nrk / 早産 / 分娩遅延 / NRK / 胎盤 Less
  • Research Projects

    (6 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (9 People)
  •  新規周産期うつ病モデルを用いた分子病態解析と抗うつ薬の開発Principal Investigator

    • Principal Investigator
      伊藤 日加瑠
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Kagawa University
  •  In vivo study of the maternal envionment and delivery system.

    • Principal Investigator
      Kanai Masami
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of a novel depression model in female mice.Principal Investigator

    • Principal Investigator
      Ito Hikaru
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kagawa University
  •  Pathophysiological mechanisms for microcephaly and macrocephalyPrincipal Investigator

    • Principal Investigator
      Hikaru Ito
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Generation of myogenic stem cells from iPS cells via blastocyst complementation.Principal Investigator

    • Principal Investigator
      Ito Hikaru
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurology
    • Research Institution
      Hiroshima University
  •  新規病態関連分子をターゲットとしたポリグルタミン病の治療効果Principal Investigator

    • Principal Investigator
      伊藤 日加瑠
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019 2018 2017 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Chronic non-discriminatory social defeat stress during the perinatal period induces depressive-like outcomes in female mice2024

    • Author(s)
      Ito Masumi、Ito Hikaru、Miyoshi Kaori、Kanai-Azuma Masami
    • Journal Title

      Brain Research

      Volume: 1825 Pages: 148734-148734

    • DOI

      10.1016/j.brainres.2023.148734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K05998
  • [Journal Article] Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors2023

    • Author(s)
      Li Wan-Ru、Nakano Takashi、Mizutani Kohta、Matsubara Takanori、Kawatani Masahiro、Mukai Yasutaka、Danjo Teruko、Ito Hikaru、Aizawa Hidenori、Yamanaka Akihiro、Petersen Carl C.H.、Yoshimoto Junichiro、Yamashita Takayuki
    • Journal Title

      Current Biology

      Volume: 33 Issue: 16 Pages: 3436-3451

    • DOI

      10.1016/j.cub.2023.07.013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18256, KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-21K05998, KAKENHI-PROJECT-21K19315, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21H02581
  • [Journal Article] A possible function of <i>Nik-related kinase</i> in the labyrinth layer of delayed delivery mouse placentas2023

    • Author(s)
      Hiroshi Yomogita, Hikaru Ito, Kento Hashimoto, Akihiko Kudo, Toshiaki Fukushima, Tsutomu Endo, Yoshikazu Hirate, Yoshihiro Akimoto, Masayuki Komada, Yoshiakira Kanai, Naoyuki Miyasaka, Masami Kanai-Azuma
    • Journal Title

      J. Reprod. Dev.

      Volume: 69 Issue: 1 Pages: 32-40

    • DOI

      10.1262/jrd.2022-120

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02387, KAKENHI-PROJECT-19K09821, KAKENHI-PROJECT-22K06039, KAKENHI-PROJECT-22K06816, KAKENHI-PROJECT-21K05998, KAKENHI-PROJECT-23K21308
  • [Journal Article] Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress2020

    • Author(s)
      Nozaki Kanako、Ito Hikaru、Ohgidani Masahiro、Yamawaki Yosuke、Sahin Ezgi Hatice、Kitajima Takashi、Katsumata Seishi、Yamawaki Shigeto、Kato Takahiro A.、Aizawa Hidenori
    • Journal Title

      Neuropharmacology

      Volume: 162 Pages: 107835-107835

    • DOI

      10.1016/j.neuropharm.2019.107835

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-18H04042
  • [Journal Article] Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress.2020

    • Author(s)
      Cui, W., Aida, T., Ito, H., Kobayashi, K., Wada, Y., Kato, S., Nakano, T., Zhu, M., Isa, K., Kobayashi, K., Isa, T., Tanaka, K. and Aizawa, H.
    • Journal Title

      J Neurosci.

      Volume: 40 Issue: 38 Pages: 7241-7254

    • DOI

      10.1523/jneurosci.0444-20.2020

    • NAID

      120007170786

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06912, KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K19494
  • [Journal Article] Activation of proprotein convertase in the mouse habenula causes depressive-like behaviors through remodeling of extracellular matrix2020

    • Author(s)
      Ito Hikaru、Nozaki Kanako、Sakimura Kenji、Abe Manabu、Yamawaki Shigeto、Aizawa Hidenori
    • Journal Title

      Neuropsychopharmacology

      Volume: 46 Issue: 2 Pages: 442-454

    • DOI

      10.1038/s41386-020-00843-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-19K17112
  • [Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019

    • Author(s)
      Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
    • Journal Title

      Neurochemistry International

      Volume: 131 Pages: 104563-104563

    • DOI

      10.1016/j.neuint.2019.104563

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
  • [Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice2018

    • Author(s)
      Yamawaki Y, Yoshioka N, Nozaki K, Ito H, Oda K, Harada K, Shirawachi S, Asano S, Aizawa H, Yamawaki S, Kanematsu T, Akagi H
    • Journal Title

      Brain research

      Volume: 1;1680 Pages: 13-38

    • DOI

      10.1016/j.brainres.2017.12.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16H07001, KAKENHI-PROJECT-17K11644
  • [Journal Article] Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.2017

    • Author(s)
      Fujita K, Mao Y, Uchida S, Chen X, Shiwaku H, Tamura T, Ito H, Watase K, Homma H, Tagawa K, Sudol M, Okazawa H.
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 1864-1864

    • DOI

      10.1038/s41467-017-01790-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16367, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16H07001
  • [Presentation] 新たなうつ病モデル雌マウスの作製2024

    • Author(s)
      伊藤 日加瑠、伊藤 益美、三好 香央梨、金井 正美
    • Organizer
      第46回日本神経科学大会(仙台)
    • Data Source
      KAKENHI-PROJECT-21K05998
  • [Presentation] 慢性ストレス負荷うつ病モデルマウスの手綱核におけるPcsk5発現増加と神経炎症2022

    • Author(s)
      伊藤日加瑠、野崎香菜子、相澤秀紀
    • Organizer
      日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-21K05998
  • [Presentation] マウス、ヒト胎盤におけるNrk下流遺伝子群と分娩遅延の関連について2021

    • Author(s)
      蓬田裕、高峰愛幸、伊藤日加瑠、平手良和、福嶋俊明、駒田雅之、金井克晃、宮坂尚幸、金井正美
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-21H02387
  • [Presentation] 細胞外基質分解酵素の不活性化によるうつ病モデルマウスの治療2020

    • Author(s)
      伊藤日加瑠、野崎香菜子、相澤秀紀
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K06504
  • [Presentation] Generation of myogenic stem cells from iPS cells via blastocyst complementation.2019

    • Author(s)
      伊藤日加瑠
    • Organizer
      第66回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K06504
  • [Presentation] Blastocyst complementation法を用いた骨格筋幹細胞の産生2017

    • Author(s)
      伊藤日加瑠, 朝倉よう子, 朝倉淳
    • Organizer
      日本解剖学会第72回中国・四国支部学術集会
    • Data Source
      KAKENHI-PROJECT-16H07001
  • [Presentation] Generation of myogenic stem cells from iPS cells via blastocyst complementation.2017

    • Author(s)
      Hikaru Ito, Yoko Asakura, Atsushi Asakura
    • Organizer
      2017年度生命科学系学会合同年次大会(日本分子生物学会)
    • Data Source
      KAKENHI-PROJECT-16H07001
  • [Presentation] Blastocyst complementation法を用いた骨格筋幹細胞の産生2017

    • Author(s)
      伊藤日加瑠、朝倉よう子、朝倉淳
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H07001
  • [Presentation] HMGB1を用いた脊髄小脳変性症1型モデルマウス治療への試み2013

    • Author(s)
      伊藤日加瑠
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1を用いた脊髄小脳変性症1型モデルマウス治療の試み2013

    • Author(s)
      伊藤日加瑠
    • Organizer
      Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1を用いた脊髄小脳変性症1型モデルマウス治療の試み2013

    • Author(s)
      伊藤日加瑠
    • Organizer
      第54回日本神経病理学会総会学術研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1 as a therapeutic molecule candidate for spinocerebellar ataxia type1 (SAC1). ~脊髄小脳変性症1型(SCA1)の治療候補分子HMGB1~2012

    • Author(s)
      Hikaru Ito
    • Organizer
      第35回日本分子生物学会総会
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1を用いた脊髄小脳変性症1型モデルマウス治療の試み

    • Author(s)
      伊藤日加瑠
    • Organizer
      平成24年度難治疾患研究所研究発表会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1 as a therapeutic molecule candidate for spinocerebellar ataxia type1

    • Author(s)
      Hikaru Ito
    • Organizer
      The 2nd International Conference of Neural Tissue Culture
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23700373
  • [Presentation] HMGB1を用いた脊髄小脳変性症1型モデルマウス治療の試み

    • Author(s)
      伊藤日加瑠
    • Organizer
      第5回東京医科歯科大学脳機能統合機能研究センター若手インスパイアシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23700373
  • 1.  Kanai Masami (70321883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  Asakura Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  Asakura Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  KATO Shigeki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  相澤 秀紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  兼松 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  山脇 洋輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  浅野 智志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  塩飽 裕紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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