Ito Hikaru 伊藤日加瑠

… Alternative Names

伊藤日加瑠イトウヒカル

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Researcher Number	50587392
Other IDs
Affiliation (Current)	2025: 香川大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 香川大学, 医学部, 准教授 2021 – 2023: 香川大学, 医学部, 准教授 2018 – 2020: 東京医科歯科大学, 統合研究機構, 助教 2017: 広島大学, 医歯薬保健学研究科(医), 助教 2016: 広島大学, 医歯薬保健学研究院(医), 助教 2012: 東京医科歯科大学, 難治疾患研究所, 助教 2011: 東京医科歯科大学, 難治疾患研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Basic Section 42040:Laboratory animal science-related / Basic Section 46020:Anatomy and histopathology of nervous system-related / Neurology / Neuroscience in general Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 42040:Laboratory animal science-related
Keywords	Principal Investigator 神経科学 / モデル動物 / 精神疾患 / 周産期 / うつ病 / モデルマウス / 精神的ストレス / 周産期うつ病 / 実験動物 / ストレス … More / 分化 / 発達障害 / 発生 / 小頭症 / 神経発達障害 / 細胞・組織 / 動物 / 発生・分化 / 移植・再生医療 / 老化 / 再生医学 / キメラ / 骨格筋 / サルコペニア / 筋ジストロフィー / 発生工学 / 胚盤胞胚補完法 / 骨格筋幹細胞 / 再生医療 / 神経病理 / 病態脳 / AAVベクター / 治療 / ポリグルタミン病 / 神経変性疾患 … More Except Principal Investigator 神経病態 / 加齢 / シヌクレイン / ミクログリア / パーキンソン病 / 分娩 / Nrk / 早産 / 分娩遅延 / NRK / 胎盤 Less

ミクログリアの加齢性変化とパーキンソン病病態におけるITGA9の役割
- Principal Investigator
  
  伊藤益美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kagawa University
新規周産期うつ病モデルを用いた分子病態解析と抗うつ薬の開発Principal Investigator
- Principal Investigator
  
  伊藤日加瑠
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kagawa University
In vivo study of the maternal envionment and delivery system.
- Principal Investigator
  
  Kanai Masami
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokyo Medical and Dental University
Development of a novel depression model in female mice.Principal Investigator
- Principal Investigator
  
  Ito Hikaru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kagawa University
Pathophysiological mechanisms for microcephaly and macrocephalyPrincipal Investigator
- Principal Investigator
  
  Hikaru Ito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Tokyo Medical and Dental University
Generation of myogenic stem cells from iPS cells via blastocyst complementation.Principal Investigator
- Principal Investigator
  
  Ito Hikaru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurology
- Research Institution
  Hiroshima University
新規病態関連分子をターゲットとしたポリグルタミン病の治療効果Principal Investigator
- Principal Investigator
  
  伊藤日加瑠
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019 2018 2017 2013 2012 Other

All Journal Article Presentation

[Journal Article] Chronic non-discriminatory social defeat stress during the perinatal period induces depressive-like outcomes in female mice2024
- Author(s)
  Ito Masumi、Ito Hikaru、Miyoshi Kaori、Kanai-Azuma Masami
- Journal Title
  
  Brain Research
  
  Volume: 1825 Pages: 148734-148734
- DOI
  10.1016/j.brainres.2023.148734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05998
[Journal Article] Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors2023
- Author(s)
  Li Wan-Ru、Nakano Takashi、Mizutani Kohta、Matsubara Takanori、Kawatani Masahiro、Mukai Yasutaka、Danjo Teruko、Ito Hikaru、Aizawa Hidenori、Yamanaka Akihiro、Petersen Carl C.H.、Yoshimoto Junichiro、Yamashita Takayuki
- Journal Title
  
  Current Biology
  
  Volume: 33 Issue: 16 Pages: 3436-3451
- DOI
  10.1016/j.cub.2023.07.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18256, KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-21K05998, KAKENHI-PROJECT-21K19315, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21H02581
[Journal Article] A possible function of <i>Nik-related kinase</i> in the labyrinth layer of delayed delivery mouse placentas2023
- Author(s)
  Hiroshi Yomogita, Hikaru Ito, Kento Hashimoto, Akihiko Kudo, Toshiaki Fukushima, Tsutomu Endo, Yoshikazu Hirate, Yoshihiro Akimoto, Masayuki Komada, Yoshiakira Kanai, Naoyuki Miyasaka, Masami Kanai-Azuma
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 69 Issue: 1 Pages: 32-40
- DOI
  10.1262/jrd.2022-120
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02387, KAKENHI-PROJECT-19K09821, KAKENHI-PROJECT-22K06039, KAKENHI-PROJECT-22K06816, KAKENHI-PROJECT-21K05998, KAKENHI-PROJECT-23K21308
[Journal Article] Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress2020
- Author(s)
  Nozaki Kanako、Ito Hikaru、Ohgidani Masahiro、Yamawaki Yosuke、Sahin Ezgi Hatice、Kitajima Takashi、Katsumata Seishi、Yamawaki Shigeto、Kato Takahiro A.、Aizawa Hidenori
- Journal Title
  
  Neuropharmacology
  
  Volume: 162 Pages: 107835-107835
- DOI
  10.1016/j.neuropharm.2019.107835
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-18H04042
[Journal Article] Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress.2020
- Author(s)
  Cui, W., Aida, T., Ito, H., Kobayashi, K., Wada, Y., Kato, S., Nakano, T., Zhu, M., Isa, K., Kobayashi, K., Isa, T., Tanaka, K. and Aizawa, H.
- Journal Title
  
  J Neurosci.
  
  Volume: 40 Issue: 38 Pages: 7241-7254
- DOI
  10.1523/jneurosci.0444-20.2020
- NAID
  120007170786
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K19494
[Journal Article] Activation of proprotein convertase in the mouse habenula causes depressive-like behaviors through remodeling of extracellular matrix2020
- Author(s)
  Ito Hikaru、Nozaki Kanako、Sakimura Kenji、Abe Manabu、Yamawaki Shigeto、Aizawa Hidenori
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 46 Issue: 2 Pages: 442-454
- DOI
  10.1038/s41386-020-00843-0
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-19K17112
[Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019
- Author(s)
  Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Neurochemistry International
  
  Volume: 131 Pages: 104563-104563
- DOI
  10.1016/j.neuint.2019.104563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
[Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice2018
- Author(s)
  Yamawaki Y, Yoshioka N, Nozaki K, Ito H, Oda K, Harada K, Shirawachi S, Asano S, Aizawa H, Yamawaki S, Kanematsu T, Akagi H
- Journal Title
  
  Brain research
  
  Volume: 1;1680 Pages: 13-38
- DOI
  10.1016/j.brainres.2017.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16H07001, KAKENHI-PROJECT-17K11644
[Journal Article] Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.2017
- Author(s)
  Fujita K, Mao Y, Uchida S, Chen X, Shiwaku H, Tamura T, Ito H, Watase K, Homma H, Tagawa K, Sudol M, Okazawa H.
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1864-1864
- DOI
  10.1038/s41467-017-01790-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16367, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16H07001
[Presentation] 新たなうつ病モデル雌マウスの作製2024
- Author(s)
  伊藤日加瑠、伊藤益美、三好香央梨、金井正美
- Organizer
  第46回日本神経科学大会（仙台）
- Data Source
  KAKENHI-PROJECT-21K05998
[Presentation] 慢性ストレス負荷うつ病モデルマウスの手綱核におけるPcsk5発現増加と神経炎症2022
- Author(s)
  伊藤日加瑠、野崎香菜子、相澤秀紀
- Organizer
  日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K05998
[Presentation] マウス、ヒト胎盤におけるNrk下流遺伝子群と分娩遅延の関連について2021
- Author(s)
  蓬田裕、高峰愛幸、伊藤日加瑠、平手良和、福嶋俊明、駒田雅之、金井克晃、宮坂尚幸、金井正美
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H02387
[Presentation] 細胞外基質分解酵素の不活性化によるうつ病モデルマウスの治療2020
- Author(s)
  伊藤日加瑠、野崎香菜子、相澤秀紀
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K06504
[Presentation] Generation of myogenic stem cells from iPS cells via blastocyst complementation.2019
- Author(s)
  伊藤日加瑠
- Organizer
  第66回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K06504
[Presentation] Blastocyst complementation法を用いた骨格筋幹細胞の産生2017
- Author(s)
  伊藤日加瑠, 朝倉よう子, 朝倉淳
- Organizer
  日本解剖学会第72回中国・四国支部学術集会
- Data Source
  KAKENHI-PROJECT-16H07001
[Presentation] Generation of myogenic stem cells from iPS cells via blastocyst complementation.2017
- Author(s)
  Hikaru Ito, Yoko Asakura, Atsushi Asakura
- Organizer
  2017年度生命科学系学会合同年次大会（日本分子生物学会）
- Data Source
  KAKENHI-PROJECT-16H07001
[Presentation] Blastocyst complementation法を用いた骨格筋幹細胞の産生2017
- Author(s)
  伊藤日加瑠、朝倉よう子、朝倉淳
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H07001
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療への試み2013
- Author(s)
  伊藤日加瑠
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み2013
- Author(s)
  伊藤日加瑠
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み2013
- Author(s)
  伊藤日加瑠
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1 as a therapeutic molecule candidate for spinocerebellar ataxia type1 (SAC1).　～脊髄小脳変性症１型（SCA1）の治療候補分子HMGB1～2012
- Author(s)
  Hikaru Ito
- Organizer
  第35回日本分子生物学会総会
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み
- Author(s)
  伊藤日加瑠
- Organizer
  平成24年度難治疾患研究所研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1 as a therapeutic molecule candidate for spinocerebellar ataxia type1
- Author(s)
  Hikaru Ito
- Organizer
  The 2nd International Conference of Neural Tissue Culture
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23700373
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み
- Author(s)
  伊藤日加瑠
- Organizer
  第5回東京医科歯科大学脳機能統合機能研究センター若手インスパイアシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23700373

1. Kanai Masami (70321883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 伊藤益美 (10814345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Asakura Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. Asakura Yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. KATO Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 相澤秀紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 兼松隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山脇洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 浅野智志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 塩飽裕紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Hikaru 伊藤 日加瑠

伊藤 日加瑠 イトウ ヒカル

Research Projects

Research Products

Co-Researchers

ミクログリアの加齢性変化とパーキンソン病病態におけるITGA9の役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規周産期うつ病モデルを用いた分子病態解析と抗うつ薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo study of the maternal envionment and delivery system.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel depression model in female mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological mechanisms for microcephaly and macrocephalyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of myogenic stem cells from iPS cells via blastocyst complementation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規病態関連分子をターゲットとしたポリグルタミン病の治療効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chronic non-discriminatory social defeat stress during the perinatal period induces depressive-like outcomes in female mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A possible function of <i>Nik-related kinase</i> in the labyrinth layer of delayed delivery mouse placentas2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Activation of proprotein convertase in the mouse habenula causes depressive-like behaviors through remodeling of extracellular matrix2020

Author(s)

Journal Title

DOI

Data Source

Ito Hikaru 伊藤日加瑠

伊藤日加瑠イトウヒカル

[Presentation] HMGB1 as a therapeutic molecule candidate for spinocerebellar ataxia type1 (SAC1).　～脊髄小脳変性症１型（SCA1）の治療候補分子HMGB1～2012