KUROKI Hideyuki 黒木秀幸

Researcher Number	50594876
Other IDs
Affiliation (based on the past Project Information) *help	2019: 熊本大学, 病院, 非常勤診療医師 2015 – 2018: 熊本大学, 医学部附属病院, 非常勤診療医師
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator TSP-1 / LSKL peptide / Sorafenib / TGF-β / Hepatectomy / HCC / 肝再生 / 肝切除術 / SB203580 / p38 MAP kinase … More / sorafenib / Thrombospondin 1 / 肝細胞癌 / 肝中心静脈閉塞症 / bevacizumab / Thrombospondin-1（TSP-1） / oxaliplatin / 肝類洞閉塞症候群 / 大腸癌肝転移 … More Except Principal Investigator Smad2 / 増殖 / 肝肥大 / 肝血流低下 / アポトーシス / 増殖抑制 / 肝類洞内皮細胞 / 肝細胞アポトーシス誘導 / 肝細胞増殖抑制 / TSP-1 / 肝萎縮 / 門脈血流低下 Less

TSP-1 expression of hepatocellular carcinoma in recurrence and metastasis after hepatectomy: the mechanism and therapeutic strategy.Principal Investigator
- Principal Investigator
  
  Kuroki Hideyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Clarification the molecular mechanism of chemotherapy-related sinusoidal obstructive syndrome and the study for efficacy of anti–vascular endothelial growth factor therapy.Principal Investigator
- Principal Investigator
  
  KUROKI Hideyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
The mechanism of liver atrophy after portal vein hypoperfusion and therapeutic method using LSKL peptide
- Principal Investigator
  
  IKUTA Yoshiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Enhancer of zeste homolog 2 (EZH2) regulates tumor angiogenesis and predicts recurrence and prognosis of intrahepatic cholangiocarcinoma2018
- Author(s)
  Nakagawa Shigeki、Okabe Hirohisa、Ouchi Mayuko、Tokunaga Ryuma、Umezaki Naoki、Higashi Takaaki、Kaida Takatoshi、Arima Kota、Kitano Yuki、Kuroki Hideyuki、Mima Kosuke、Nitta Hidetoshi、Imai Katsunori、Hashimoto Daisuke、Yamashita Yo-ichi、Chikamoto Akira、Baba Hideo
- Journal Title
  
  HPB
  
  Volume: 20 Issue: 10 Pages: 939-948
- DOI
  10.1016/j.hpb.2018.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-18K16369, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16K19939
[Journal Article] Erratum to: Sarcopenia, but not visceral fat amount, is a risk factor of postoperative complications after major hepatectomy.2017
- Author(s)
  Higashi T, Hayashi H, Taki K, Sakamoto K, Kuroki H, Nitta H, Hashimoto D, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 22(5) Issue: 5 Pages: 986-990
- DOI
  10.1007/s10147-017-1163-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10670
[Journal Article] Thrombospondin-1 expression may be implicated in liver atrophic mechanism due to obstructed portal venous flow.2016
- Author(s)
  Hayashi H, Kuroki H, Higashi T, Takeyama H, Yokoyama N, Okabe H, Nitta H, Beppu T, Takamori H, Baba H.
- Journal Title
  
  Hepatol Res
  
  Volume: Epub Issue: 8 Pages: 803-812
- DOI
  10.1111/hepr.12792
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462046, KAKENHI-PROJECT-17K10670
[Journal Article] An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression.2015
- Author(s)
  Hayashi H, Higashi T, Yokoyama N, Kaida T, Sakamoto K, Fukushima Y, Ishimoto T, Kuroki H, Nitta H, Hashimoto D, Chikamoto A, Oki E, Beppu T, Baba H.
- Journal Title
  
  Cancer Res.
  
  Volume: 75(22) Issue: 22 Pages: 4985-97
- DOI
  10.1158/0008-5472.can-15-0291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-26462046, KAKENHI-PROJECT-25462098, KAKENHI-PROJECT-26293290
[Journal Article] Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy2015
- Author(s)
  Hayashi H, Beppu T, Okabe H, Kuroki H, Nakagawa S, Imai K, Nitta H, Chikamoto A, Ishiko T, Baba H
- Journal Title
  
  Surgery
  
  Volume: 157(1) Issue: 1 Pages: 20-6
- DOI
  10.1016/j.surg.2014.06.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592034, KAKENHI-PROJECT-26861088, KAKENHI-PROJECT-26462046
[Journal Article] The modified Glasgow Prognostic Score (mGPS) is a good predictor of indication for palliative bypass surgery in patients with unresectable pancreatic and biliary cancers2014
- Author(s)
  Ikuta Y, Takamori H, Sakamoto Y, Hashimoto D, Chikamoto A, Kuroki H, Sakata K, Sakamoto K, Hayashi H, Imai K, Nitta H, Hirota M, Kanemitsu K, Beppu T, Baba H
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 19(4) Issue: 4 Pages: 629-33
- DOI
  10.1007/s10147-013-0613-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791384, KAKENHI-PROJECT-26462046
[Presentation] 肝再生および肝萎縮におけるトロンボスポンディン1の役割解明と臨床応用への探索2017
- Author(s)
  林洋光、黒木秀幸、東孝暁、武山秀晶、岡部弘尚、今井克憲、山下洋市、高森啓史、馬場秀夫
- Organizer
  第117回日本外科学会定期学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-26462046
[Presentation] 血中TSP-1は肝切除後の肝障害および肝機能を予測する因子として有用である2017
- Author(s)
  黒木秀幸
- Organizer
  第72回日本消化器外科学会総会
- Place of Presentation
  石川県立音楽堂（石川県）
- Year and Date
  2017-07-20
- Data Source
  KAKENHI-PROJECT-15K19898
[Presentation] 肝再生および肝萎縮におけるトロンボスポンディン1の役割解明と臨床応用への探索2017
- Author(s)
  林洋光、黒木秀幸、東孝暁:、武山秀晶、岡部弘尚、今井克憲、山下洋市、高森啓史、馬場秀夫
- Organizer
  第117回　日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10670
[Presentation] 肝切除後の血漿中Thrombospondin-1変化の肝障害の予測因子としての可能性2016
- Author(s)
  黒木秀幸、林洋光、中川茂樹、東孝暁、橋本大輔、新田英利、近本　亮、石河隆敏、別府　透、馬場秀夫
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-26462046
[Presentation] 肝切除後の血漿中Thrombospondin-1変化の肝障害の予測因子としての可能性2016
- Author(s)
  黒木秀幸、林洋光、中川茂樹、東孝暁、橋本大輔、新田英利、近本　亮、石河隆敏、別府　透、馬場秀夫
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-15K19898

1. HAYASHI Hiromitsu (80625773)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. HIGASHI Takaaki (70594878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. NAKAGAWA Shigeki (10594872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. IKUTA Yoshiaki (70452894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 近本亮 (10419640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 馬場秀夫 (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 今井克憲 (60555746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. YAMAMURA Kensuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MIYAKE Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 新田英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUROKI Hideyuki 黒木 秀幸

Research Projects

Research Products

Co-Researchers

TSP-1 expression of hepatocellular carcinoma in recurrence and metastasis after hepatectomy: the mechanism and therapeutic strategy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification the molecular mechanism of chemotherapy-related sinusoidal obstructive syndrome and the study for efficacy of anti&#8211;vascular endothelial growth factor therapy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of liver atrophy after portal vein hypoperfusion and therapeutic method using LSKL peptide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Enhancer of zeste homolog 2 (EZH2) regulates tumor angiogenesis and predicts recurrence and prognosis of intrahepatic cholangiocarcinoma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Erratum to: Sarcopenia, but not visceral fat amount, is a risk factor of postoperative complications after major hepatectomy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thrombospondin-1 expression may be implicated in liver atrophic mechanism due to obstructed portal venous flow.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The modified Glasgow Prognostic Score (mGPS) is a good predictor of indication for palliative bypass surgery in patients with unresectable pancreatic and biliary cancers2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝再生および肝萎縮におけるトロンボスポンディン1の役割解明と臨床応用への探索2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 血中TSP-1は肝切除後の肝障害および肝機能を予測する因子として有用である2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 肝再生および肝萎縮におけるトロンボスポンディン1の役割解明と臨床応用への探索2017

Author(s)

Organizer

Data Source

[Presentation] 肝切除後の血漿中Thrombospondin-1変化の肝障害の予測因子としての可能性2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 肝切除後の血漿中Thrombospondin-1変化の肝障害の予測因子としての可能性2016

Author(s)

Organizer

Place of Presentation

Data Source

KUROKI Hideyuki 黒木秀幸

Clarification the molecular mechanism of chemotherapy-related sinusoidal obstructive syndrome and the study for efficacy of anti–vascular endothelial growth factor therapy.Principal Investigator