Shiba Norio 柴徳生

… Alternative Names

SHIBA NORIO 柴徳生

SHIBA Norio 柴徳生

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Researcher Number	50600615
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員准教授
Affiliation (based on the past Project Information) *help	2025: 横浜市立大学, 医学研究科, 客員准教授 2019 – 2021: 横浜市立大学, 附属病院, 講師 2018: 横浜市立大学, 医学部, 講師 2017: 横浜市立大学, 医学部, 助教 2016: 群馬大学, 医学部附属病院, 助教 … More 2013 – 2014: 群馬大学, 医学部附属病院, 助教 2012: 群馬大学, 医学部附属病院小児科 2011: 群馬大学, 医学部, 医員 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 急性骨髄性白血病 / 小児 / DNAメチル化 / 治療層別化 / 遺伝子変異解析 / 遺伝子発現 / AML / ATACシーケンス / 遺伝子解析 / microRNAシーケンス … More / Chipシーケンス / micro RNA / ATAC-seq / プロテオーム解析 / メチル化アレイ解析 / 遺伝子発現解析 / メチル化アレイ / 予後予測 / 抑制性ポリコーム / FLT3-ITD / PRDM16 / DNMT3A / JMML / 白血病 / NUP98-NSD1 / CBL … More Except Principal Investigator インプリンティング / 癌 / マイクロアレイ / ゲノム / 遺伝子 / 小児腫瘍学 Less

PRDM16遺伝子高発現難治急性骨髄性白血病に対する分子標的薬の開発Principal Investigator
- Principal Investigator
  
  柴徳生
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Yokohama City University
Epigenomic analysis in refractory AMLPrincipal Investigator
- Principal Investigator
  
  SHIBA Norio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Yokohama City University
Identification of molecular target of high risk pediatric AML by comprehensive genetic analysisPrincipal Investigator
- Principal Investigator
  
  SHIBA NORIO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Yokohama City University
  Gunma University
Comprehensive genetic analysis of pediatric acute myeloid leukemiaPrincipal Investigator
- Principal Investigator
  
  SHIBA NORIO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hematology
- Research Institution
  Gunma University
乳児期を中心とした小児急性白血病と骨髄異形成症候群における新規原因遺伝子の解析Principal Investigator
- Principal Investigator
  
  柴徳生
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Gunma University
Genome wide analysis of imprinting gene in pediatric solid tumor
- Principal Investigator
  
  HAYASHI Yasuhide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Gunma Institute of Public Health and Environmental Sciences

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Other

[Journal Article] Genome-wide DNA Methylation Analysis in Pediatric Acute Myeloid Leukemia.2022
- Author(s)
  Yamato G, Kawai T, Shiba N, Ikeda J, Hara Y, Ohki K, Tsujimoto SI, Kaburagi T, Yoshida K, Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Taga T, Horibe K, Ogawa S, Hata K, Hayashi Y.
- Journal Title
  
  Blood advances
  
  Volume: in press Issue: 11 Pages: 3207-3219
- DOI
  10.1182/bloodadvances.2021005381
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K16762, KAKENHI-PROJECT-20K08157, KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-21K20937, KAKENHI-PROJECT-20K17414
[Journal Article] Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts.2021
- Author(s)
  Sasaki K, Tsujimoto S, Miyake M, Uchiyama Y, Ikeda J, Yoshitomi M, Shimosato Y, Tokumasu M, Matsuo H, Yoshida K, Ohki K, Kaburagi T, Yamato G, Hara Y, Takeuchi M, Kinoshita A, Tomizawa D, Taga T, Adachi S, Tawa A, Horibe K, Hayashi Y, Matsumoto N, Ito S, Shiba N.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 194(2) Issue: 2 Pages: 414-422
- DOI
  10.1111/bjh.17569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K16762, KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-20K17414, KAKENHI-PROJECT-21K20937
[Journal Article] Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia.2021
- Author(s)
  Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Tabuchi K, Shiraishi Y,Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y.
- Journal Title
  
  Haematologica
  
  Volume: － Issue: 3 Pages: 583-592
- DOI
  10.3324/haematol.2020.269431
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20K08157, KAKENHI-PROJECT-20K17414, KAKENHI-PROJECT-20K08744, KAKENHI-PROJECT-21K20937
[Journal Article] Allogeneic Bone Marrow Transplantation versus Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies in Children: A Systematic Review and Meta-Analysis.2020
- Author(s)
  Shimosato Y, Tanoshima R, Tsujimoto SI, Takeuchi M, Shiba N, Kobayashi T, Ito S.
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 26 Issue: 1 Pages: 88-93
- DOI
  10.1016/j.bbmt.2019.07.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08350
[Journal Article] A 2‐year‐old patient with a diffuse intrinsic pontine glioma and radiation‐induced moyamoya syndrome.2020
- Author(s)
  Iizuka A, Shiba N, Shimosato Y, Yoshitomi M, Nakamura T, Miyatake S, Takano Y, Sasaki K, Takeuchi M, Nurata H, Yamamoto N, Ito S.
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 67 Issue: 10
- DOI
  10.1002/pbc.28618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-20K07907
[Journal Article] The outcomes of relapsed acute myeloid leukemia in children: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group AML‐05R study.2020
- Author(s)
  Moritake H, Tanaka S, Miyamura T, Nakayama H, Shiba N, Shimada A, Terui K, Yuza Y, Koh K, Goto H, Kakuda H, Saito A, Hasegawa D, Iwamoto S, Taga T, Adachi S, Tomizawa D.
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 68 Issue: 1
- DOI
  10.1002/pbc.28736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-20K08157
[Journal Article] A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma2020
- Author(s)
  Tateishi Kensuke、Miyake Yohei、Kawazu Masahito、Sasaki Nobuyoshi、Nakamura Taishi、Sasame Jo、Yoshii Yukie、Ueno Toshihide、Miyake Akio、Matsushita Yuko、Shiba Norio、Udaka Naoko、Ohki Kentaro、Fink Alexandria L.、Tummala Shilpa S.、Natsumeda Manabu、Miller Julie J.、Fujii Yukihiko、et al
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 23 Pages: 5330-5343
- DOI
  10.1158/0008-5472.can-20-2425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10888, KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K09476, KAKENHI-PROJECT-19K09488, KAKENHI-PROJECT-19K18398, KAKENHI-PROJECT-17K10057, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-18K08950, KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-19H03774
[Journal Article] Patients aged less than 3 years with acute myeloid leukaemia characterize a molecularly and clinically distinct subgroup.2020
- Author(s)
  Hara Y, Shiba N, Yamato G, Ohki K, Tabuchi K, Sotomatsu M, Tomizawa D, Kinoshita A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, Hayashi Y
- Journal Title
  
  Br J Haematol
  
  Volume: 188 Issue: 4 Pages: 528-539
- DOI
  10.1111/bjh.16203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08335, KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-19K21333
[Journal Article] Predisposition to prolonged neutropenia after chemotherapy for paediatric acute myeloid leukaemia is associated with better prognosis in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML‐05 study.2020
- Author(s)
  Aoki T, Takahashi H, Tanaka S, Shiba N, Hasegawa D, Iwamoto S, Terui K, Moritake H, Nakayama H, Shimada A, Koh K, Goto H, Kosaka Y, Saito AM, Horibe K, Kinoshita A, Tawa A, Taga T, Adachi S, Tomizawa D.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 193 Issue: 1 Pages: 176-180
- DOI
  10.1111/bjh.16656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08350
[Journal Article] Clinical and biological features of paediatric acute myeloid leukaemia (AML) with primary induction failure in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study.2019
- Author(s)
  Miyamura T, Moritake H, Nakayama H, Tanaka S, Tomizawa D, Shiba N, Saito AM, Tawa A, Shimada A, Iwamoto S, Hayashi Y, Koike T, Horibe K, Manabe A, Mizutani S, Taga T, Adachi S.
- Journal Title
  
  Br J Haematol.
  
  Volume: 19 Issue: 2 Pages: 284-288
- DOI
  10.1111/bjh.15799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17H04110, KAKENHI-PROJECT-15K09653, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-19K08350
[Journal Article] Negative CD19 expression is associated with inferior relapse‐free survival in children with RUNX1‐RUNX1T1 ?positive acute myeloid leukaemia: results from the Japanese Paediatric Leukaemia/Lymphoma Study Group AML‐05 study2019
- Author(s)
  Sakamoto Kenichi、Shiba Norio、Deguchi Takao、Kiyokawa Nobutaka、Hashii Yoshiko、Moriya‐Saito Akiko、Tomizawa Daisuke、Taga Takashi、Adachi Soichi、Horibe Keizo、Imamura Toshihiko
- Journal Title
  
  British Journal of Haematology
  
  Volume: 187 Issue: 3 Pages: 372-376
- DOI
  10.1111/bjh.16080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08350
[Journal Article] Whole transcriptome sequencing reveals a KMT2A‐USP2 fusion in infant acute myeloid leukemia2019
- Author(s)
  Ikeda Junji、Shiba Norio、Tsujimoto Shin‐ichi、Yoshida Masanori、Nakabayashi Kazuhiko、Ogata‐Kawata Hiroko、Okamura Kohji、Takeuchi Masanobu、Osumi Tomoo、Tomizawa Daisuke、Hata Kenichiro、Kiyokawa Nobutaka、Ito Shuichi、Kato Motohiro
- Journal Title
  
  Genes, Chromosomes and Cancer
  
  Volume: in press Issue: 9 Pages: 1-1
- DOI
  10.1002/gcc.22751
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07137, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-17H04234
[Journal Article] Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia2019
- Author(s)
  Shiba N, Yoshida K, Hara Y, Yamato G, Shiraishi Y, Matsuo H, Okuno Y, Chiba K, Tanaka H, Kaburagi T, Takeuchi M, Ohki K, Sanada M, Okubo J, Tomizawa D, Taki T, Shimada A, Sotomatsu M, Horibe K, Taga T, Adachi S, Tawa A, Miyano S, Ogawa S, Hayashi Y
- Journal Title
  
  Blood Adv
  
  Volume: 3 Issue: 20 Pages: 3157-3169
- DOI
  10.1182/bloodadvances.2019000404
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08335, KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K16832, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17H04110, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17K10136, KAKENHI-PROJECT-19K21333
[Journal Article] Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia2018
- Author(s)
  Matsuo Hidemasa、Itonaga Hidehiro、et al.
- Journal Title
  
  Blood Advances
  
  Volume: 2 Issue: 21 Pages: 2879-2889
- DOI
  10.1182/bloodadvances.2018019398
- NAID
  120006534600
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16189, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H03597, KAKENHI-PROJECT-17H04110, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-16K19193, KAKENHI-PROJECT-16K20951
[Journal Article] RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis.2018
- Author(s)
  1.Yamato G, Shiba N, Yoshida K, Hara Y, Shiraishi Y, Ohki K, Okubo J, Park MJ, Sotomatsu M, Arakawa H, Kiyokawa N, Tomizawa D, Adachi S, Taga T, Horibe K, Miyano S, Ogawa S, Hayashi Y.
- Journal Title
  
  Blood
  
  Volume: Epub Issue: 20 Pages: 2266-2270
- DOI
  10.1182/blood-2017-11-814442
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-17K10130, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H04110
[Journal Article] Risk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study.2018
- Author(s)
  Shimada A, Iijima-Yamashita Y, Tawa A, Tomizawa D, Yamada M, Norio S, Watanabe T, Taga T, Iwamoto S, Terui K, Moritake H, Kinoshita A, Takahashi H, Nakayama H, Koh K, Goto H, Kosaka Y, Saito AM, Kiyokawa N, Horibe K, Hara Y, Oki K, Hayashi Y, Tanaka S, Adachi S.
- Journal Title
  
  Int J Hematol.
  
  Volume: 107(5) Issue: 5 Pages: 586-595
- DOI
  10.1007/s12185-017-2395-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17H04110, KAKENHI-PROJECT-15K09653, KAKENHI-PROJECT-16K20951
[Journal Article] Comparison of conditioning regimens for autologous stem cell transplantation in children with acute myeloid leukemia: A nationwide retrospective study in Japan2018
- Author(s)
  Sakaguchi Hirotoshi、Muramatsu Hideki、Hasegawa Daiichiro、Kudo Kazuko、Ishida Hiroyuki、Yoshida Nao、Koh Katsuyoshi、Noguchi Maiko、Shiba Norio、Tokimasa Sadao、Fukuda Takhiro、Goto Hiroaki、Miyamura Takako、Nakazawa Yozo、Hashii Yoshiko、Inoue Masami、Atsuta Yoshiko、et al
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 66 Issue: 1
- DOI
  10.1002/pbc.27459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07816, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-19K08350
[Journal Article] Genetic aberrations and new treatment strategies for pediatric acute myeloid leukemia2018
- Author(s)
  柴徳生
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 10 Pages: 2260-2267
- DOI
  10.11406/rinketsu.59.2260
- NAID
  130007496727
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20951
[Journal Article] Allogeneic hematopoietic stem cell transplantation for children and adolescents with high-risk cytogenetic AML: distinctly poor outcomes of FUS-ERG-positive cases2018
- Author(s)
  Tomizawa Daisuke、Yoshida Masanori、Kondo Tadakazu、Miyamura Takako、Taga Takashi、Adachi Souichi、Koh Katsuyoshi、Noguchi Maiko、Kakuda Harumi、Watanabe Kenichiro、Cho Yuko、Fukuda Takahiro、Kato Motohiro、Shiba Norio、Goto Hiroaki、Okada Keiko、Inoue Masami、Hashii Yoshiko、Atsuta Yoshiko、Ishida Hiroyuki
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 54 Issue: 3 Pages: 393-401
- DOI
  10.1038/s41409-018-0273-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04110, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-19K08350
[Journal Article] Outcome of relapsed core binding factor acute myeloid leukemia in children: A result from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R study.2017
- Author(s)
  Moritake H, Tanaka S, Nakayama H, Miyamura T, Iwamoto S, Shimada A, Terui K, Saito A, Shiba N, Hayashi Y, Tomizawa D, Taga T, Goto H, Hasegawa D, Horibe K, Mizutani S, Adachi S.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 64(10) Issue: 10
- DOI
  10.1002/pbc.26491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-16K20951
[Journal Article] Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia2017
- Author(s)
  Yamato Genki、Yamaguchi Hiroki、Handa Hiroshi、Shiba Norio、Kawamura Machiko、Wakita Satoshi、Inokuchi Koiti、Hara Yusuke、Ohki Kentaro、Okubo Jun、Park Myoung-Ja、Sotomatsu Manabu、Arakawa Hirokazu、Hayashi Yasuhide
- Journal Title
  
  Genes, Chromosomes and Cancer
  
  Volume: 56 Issue: 11 Pages: 800-809
- DOI
  10.1002/gcc.22483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-17K09942, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-16K20951
[Journal Article] Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non-Down syndrome.2017
- Author(s)
  Hara Y, Shiba N, Ohki K, Tabuchi K, Yamato G, Park MJ, Tomizawa D, Kinoshita K, Shimada A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, and Hayashi Y.
- Journal Title
  
  Genes, Chromosomes & Cancer
  
  Volume: 14 February 2017 Issue: 5 Pages: 394-404
- DOI
  10.1002/gcc.22444
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461599, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-15K09486
[Journal Article] ASXL2 Mutations are Frequently Found in Pediatric AML Patients with t(8;21)/RUNX1-RUNX1T1 and Associated with a Better Prognosis.2017
- Author(s)
  Yamato G, Shiba N, Yoshida K, Shiraishi Y, Hara Y, Ohki K, Okubo J, Okuno H, Chiba K, Tanaka H, Kinoshita A, Moritake H, Kiyokawa N, Tomizawa D, Park MJ, Sotomatsu M, Taga T, Adachi S, Tawa A, Horibe K, Arakawa H, Miyano S, Ogawa S, Hayashi Y.
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: - Issue: 5 Pages: 382-393
- DOI
  10.1002/gcc.22443
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26461599, KAKENHI-PROJECT-16K20951, KAKENHI-PROJECT-17K10130
[Journal Article] 次世代シーケンサーによる小児血液、腫瘍疾患における研究の進展　急性骨髄性白血病における遺伝子異常2015
- Author(s)
  柴　徳生
- Journal Title
  
  日本小児血液がん学会雑誌
  
  Volume: 51 Pages: 397-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893028
[Journal Article] 癌になりやすい体質，胚細胞変異とモザイク2015
- Author(s)
  柴　徳生
- Journal Title
  
  小児外科
  
  Volume: 47 Pages: 118-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893028
[Journal Article] High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.2015
- Author(s)
  Jo A, Mitani S, Shiba N, Hayashi Y, Hara Y, Takahashi H, Tsukimoto I, Tawa A, Horibe K, Tomizawa D, Taga T, Adachi S, Yoshida T, Ichikawa H
- Journal Title
  
  Leukemia
  
  Volume: 29 Issue: 5 Pages: 1067-1083
- DOI
  10.1038/leu.2015.5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591567, KAKENHI-PROJECT-25893028, KAKENHI-PROJECT-26670277, KAKENHI-PROJECT-26461599, KAKENHI-PUBLICLY-26114703, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482
[Journal Article] CSF3R and CALR mutations in paediatric myeloid disorders and the association of CSF3R mutations with translocations, including t(8; 21).2015
- Author(s)
  Sano H, Ohki K, Park MJ, Shiba N, et al.
- Journal Title
  
  Br J Haematol.
  
  Volume: Epub ahead of print Issue: 3 Pages: 319-397
- DOI
  10.1111/bjh.13439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25893028, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26461599, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482
[Journal Article] NUP98-NSD1 related gene expression signature is strongly associated with a poor prognosis in pediatric acute myeloid leukemia: a study of the Japanese Childhood AML Cooperative Study Group Cooperative Study Group2013
- Author(s)
  Shiba N, Ichikawa H, Taki T, Park M, Jo A, Mitani S, Shimada A, Sotomatsu M, Arakawa H, Tabuchi K, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 52 Issue: 7 Pages: 683-693
- DOI
  10.1002/gcc.22064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591172, KAKENHI-PROJECT-23390273, KAKENHI-PROJECT-23591537, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24591407, KAKENHI-PROJECT-24591567, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25893028
[Journal Article] CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia2012
- Author(s)
  Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 11 Pages: 2612-2614
- DOI
  10.1182/blood-2011-02-333435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390268
[Journal Article] CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML).2012
- Author(s)
  Shiba N, Hasegawa D, Park MJ, Murata C, Sato-Otsubo A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 2612-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791151
[Journal Article] DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia.2012
- Author(s)
  Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y.
- Journal Title
  
  Br J Haematol.
  
  Volume: 156 Pages: 413-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791151
[Journal Article] DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia2012
- Author(s)
  Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y
- Journal Title
  
  Br J Haematol
  
  Volume: 156 Pages: 413-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659196
[Journal Article] DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia2012
- Author(s)
  Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y.
- Journal Title
  
  Br J Haematol
  
  Volume: 156 Issue: 3 Pages: 413-414
- DOI
  10.1111/j.1365-2141.2011.08879.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591172, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23390273, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24659273
[Journal Article] CBL mutations in infant acute lymphoblastic leukaemia.2012
- Author(s)
  Shiba N, Park MJ, Taki T, Takita J, Hiwatari M, Kanazawa T, Sotomatsu M, Ishii E, Arakawa H, Ogawa S, Hayashi Y.
- Journal Title
  
  Br J Haematol.
  
  Volume: 156 Pages: 672-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791151
[Journal Article] CBL mutation in childhood therapy-related leukemia2011
- Author(s)
  Shiba N, Taki T, Park MJ, Nagasawa M, Kanazawa T, Takita J, Ohnishi H, Sotomatsu M, Arakawa H, Hayashi Y.
- Journal Title
  
  Leukemia
  
  Volume: 25 Issue: 8 Pages: 1356-1358
- DOI
  10.1038/leu.2011.75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22591172, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23591530, KAKENHI-PROJECT-23591560
[Journal Article] Expression of ADAMTS4 in Ewing's sarcoma2010
- Author(s)
  Minobe K, Ono R, Matsumine A, Shibata-Minoshima F, Izawa K, Oki T, Kitaura J, Iino T, Takita J, Iwamoto S, Hori H, Komada Y, Uchida A, Hayashi Y, Kitamura T, Nosaka T
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 569-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659196
[Journal Article] CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome.2010
- Author(s)
  Shiba N, et al.
- Journal Title
  
  Leukemia
  
  Volume: 24 Pages: 1090-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659196
[Journal Article] NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia.2010
- Author(s)
  Shiba N, et al.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 55 Pages: 1406-1409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659196
[Journal Article] CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome2010
- Author(s)
  Shiba N, Kato M, Park MJ, Sanada M, Ito E, Fukushima K, Sako M, Arakawa H, Ogawa S, Hayashi Y.
- Journal Title
  
  Leukemia
  
  Volume: 24 Issue: 5 Pages: 1090-1092
- DOI
  10.1038/leu.2010.49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196
[Journal Article] NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia2010
- Author(s)
  Shiba N, Kanazawa T, Park MJ, Okuno H, Tamura K, Tsukada S, Hayashi Y, Arakawa H.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 55 Issue: 7 Pages: 1406-1409
- DOI
  10.1002/pbc.22758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390316, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196
[Journal Article] CBL mutation in childhood therapy-related .leukemia.
- Author(s)
  Shiba N, et al.
- Journal Title
  
  Leukemia
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659196
[Journal Article] NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with apoor prognosis inpediatric acute myeloid leukemia
- Author(s)
  Norio Shiba, et al.
- Journal Title
  
  Genes Chromosomes and Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] Cytokine Analysis in 154 Patients with Transient Abnormal Myelopoiesis: Jccg JPLSG TAM-10 Clinical Study.2021
- Author(s)
  Yamato G, MD, Park MJ, Shimada A, Shiba N, Yamada Y, Terui K, Ito E, MD, Muramatsu H, Watanabe K, and Hayashi Y.
- Organizer
  The 63rd American Society of Hematology Annual Meeting and Exposition(virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Clonal Evolution Pattern and Prognostic Significance of Clonal Architecture in KMT2A-Rearranged Acute Myeloid Leukemia.2021
- Author(s)
  Matsuo H, Yoshida K, Nannya Y, Ito Y, Saito S, Koga Y, Moritake H, Terui K, Kawaguchi K, Okamoto Y, Nakayama H, Kanno M, Hino M, Akane Y, Inoue A, Shimada A, Goto H, Ueno H, Takita J, Yamato G, Shiba N, Hayashi Y, Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Taga T, Tawa A, Ogawa S and Adachi S
- Organizer
  The 63rd American Society of Hematology Annual Meeting and Exposition(virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] The genetic landscape of pediatric acute promyelocytic leukemia - the JCCG study, JPLSG AML-P05 -（小児急性骨髄性白血病に対するカスタムパネルを用いた網羅的遺伝子解析 - the JCCG study, JPLSG AML-P05 -2020
- Author(s)
  Yamato G, Ueno H, Takahashi H, Shiba N, Ohki K, Yuza Y, Tomizawa D, Adachi S, Ogawa S, Hayashi Y
- Organizer
  第62回日本小児血液・がん学会学術集会，福島（ Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Outcome of relapsed pediatric acute leukemia in Japan: The results of 111 cases from the JPLSG AML-05R study（本邦における再発小児急性骨髄性白血病の予後：JPLSG AML-05R登録111例の解析）.2020
- Author(s)
  Moritake H, Tanaka S, Miyamura T, Nakayama H, Shiba N, Hasegawa D, Iwamoto S, Taga T, Adachi S, Tomizawa D
- Organizer
  第62回日本小児血液・がん学会学術集会，福島（ Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Thiotepaによる皮膚障害の小児例．2020
- Author(s)
  竹内正宣，林　弘明，吉富誠弘，飯塚敦広，辻本信一，田野島玲大，柴　徳生，渡邊友也，伊藤秀一
- Organizer
  第47回日本小児臨床薬理学会，前橋（Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] A bioadhesive barrier-forming lipid solution for oral mucositis of pediatric patients with chemotherapy or radiation therapy （小児の科学療法、放射線療法に伴う口腔粘膜炎への局所管理ハイドロゲル創傷被覆・保護剤の使用経験）．2020
- Author(s)
  Tanoshima R, Iizuka A, Hayashi H, Shimosato Y, Sasaki K, Tsujimoto S, Takeuchi M, Ohashi N, Shiba N
- Organizer
  第62回日本小児血液・がん学会学術集会，福島（ Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] 当院における新生児貧血5例に対する診断および治療戦略．2020
- Author(s)
  柴　徳生，瀧澤かすみ，黒沢英里，小峰弘美，岩上　薫，原田佐保，飯塚淳広，吉富誠弘，佐々木康二，剱持孝博、魚住　梓，竹内正宣，伊藤秀一
- Organizer
  第68回日本輸血・細胞治療学会学術総会，札幌
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] A pediatric case of acute lymphoblastic leukemia with DVT and PYE（T細胞性急性リンパ性白血病治療中に深部静脈血栓症・肺動脈血栓塞栓症を合併した1例）.2020
- Author(s)
  飯塚淳広，下里侑子，吉富誠弘，佐々木康二，竹内正宣，柴　徳生，伊藤秀一
- Organizer
  第123回日本小児科学会学術総会, 神戸
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] 内部制度管理における試験管法目合わせの取り組み．2020
- Author(s)
  岩上　薫，瀧澤かすみ，黒沢英里，小峰弘美，原田佐保，山崎悦子，柴　徳生，上條亜紀
- Organizer
  第68回日本輸血・細胞治療学会学術総会，札幌
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Etoposide, Cytarabine and Mitoxantrone- or Fludarabine, Cytarabine and Granulocyte Colony-Stimulating Factor-Based Intensive Reinduction Chemotherapy Is Recommended for Children with Relapsed Acute Myeloid Leukemia: The Results from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R Study.2020
- Author(s)
  Moritake H, Tanaka S, Miyamura T, Nakayama H, Shiba N, Shimada A, Terui K, Yuza Y, Koh K, Goto H, Kakuda H, Saito A M, Hasegawa D, Iwamoto S, Taga T, Adachi S, Tomizawa D
- Organizer
  The 62nd ASH Annual Meeting and Exposition (virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] 服薬不遵守は国境を超えた問題である - 日加双方での小児がん患者の内服抗腫瘍薬服薬不遵守の経験を通して -2020
- Author(s)
  田野島玲大，竹内正宣，吉富誠弘，Bruce C Carleton，佐々木康二，柴　徳生，伊藤秀一
- Organizer
  第47回日本小児臨床薬理学会学術集会，前橋（Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity.2020
- Author(s)
  Nishimura A, Yokoyama K, Yamagishi C, Imamura T, Naruto T, Morio T, Tanaka Y, Kanai A, Matsui H, Higuchi N, Shiba N, Miki M, Kimura F, Nakayama H, Nakazawa Y, Taga T, Taki T, Adachi S, Manabe A, Koh K, Ishida Y, Tojo A, Takagi M. et.al.
- Organizer
  The 62nd ASH Annual Meeting and Exposition (virtual)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] High gene expression of DOCK1 shows poor prognosis in children with acute myeloid leukemia（小児急性骨髄性白血病においてDOCK1遺伝子高発現は予後不良因子となり得る）．2020
- Author(s)
  Yoshitomi M, Ikeda J, Tsujimoto S, Ito S, Hasegawa D, Iwamoto S, Hayashi Y, Adachi S, Tomizawa D, Shiba N
- Organizer
  第62回日本小児血液・がん学会学術集会，福島（ Web）
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Significant Feature of DNA Methylation at Bivalent Promotor and Repressed Polycomb Regions in Padiatric AML-the Jccg Study, JPLSG AML-05-.2019
- Author(s)
  Yamato G, Kawai T, Shiba N, Hara Y, Ohki K, Kaburagi T, Yoshida K, Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Tago T, Horibe K, Ogawa S, Hata K, Hayashi Y
- Organizer
  61st American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Comprehensive methylation analysis in pediatric AML patients -the JCCG, JPLSG AML-05 study-.2019
- Author(s)
  Yamato G, Kawai T, Shiba N, Hara Y, Ohki K，Kaburagi T, Yoshida K，Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Taga T，Horibe K, Ogawa S, Hata K, Hayashi Y
- Organizer
  81st Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Recurrent Gene Mutations in Peadiatric Patients with AML By Targeted Sequencing -the Jccg Study, JPLSG AML-05-.2019
- Author(s)
  Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Shiraishi Y, Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y
- Organizer
  61st American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Recurrent gene mutations in pediatric AML by targeted sequencing using a 343-gene custom panel.2019
- Author(s)
  Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Shiraishi Y, Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Adachi S, Taga T, Ogawa S, Hayashi Y
- Organizer
  81st Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Pediatric AML patients with FLT3-ITD/NUP98-NSD1 have maintained long-term complete remission.2019
- Author(s)
  Yoshitomi M，Shimosato Y，Sasaki K，Oya T，Takeuchi M，Shiba N，Ito S
- Organizer
  81st Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] 小児急性骨髄性白血病患者におけるKMT2C変異とPHF6変異の臨床的意義について．2019
- Author(s)
  鏑木多映子，大和玄季，柴　徳生，吉田健一，原　勇介，白石友一，大木健太郎，外松　学、荒川浩一，松尾英将，嶋田　明，滝　智彦，清河信敬，富澤大輔，堀部敬三，宮野　悟，足立壮一，多賀　崇，小川誠司，林　泰秀
- Organizer
  第61回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] ATAC-seqを用いた小児急性骨髄性白血病におけるオープンクロマチン領域の解析．2019
- Author(s)
  池田順二，柴　徳生，飯塚淳広，吉富誠弘，佐々木康二，竹内正宣，鏑木多映子，大和玄季，原　勇介，林　泰秀，伊藤秀一
- Organizer
  第61回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] 小児急性骨髄性白血病におけるdroplet digital PCRを用いたKIT D816V変異を有するminor cloneの検出．2019
- Author(s)
  佐々木康二，柴　徳生，内山由理，徳舛麻友，松尾英将，吉田健一，大木健太郎，大和玄季，原　勇介，木下明俊，富澤大輔，多賀　崇，足立壮一，多和昭雄，堀部敬三，松本直通，伊藤秀一
- Organizer
  第61回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] The Detection of Minor Clones with Somatic KIT D8 16V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/ Lymphoma Study Group.2019
- Author(s)
  Sasaki K, Uchiyama Y, Ikeda J, Yoshitomi M, Shimosato-Wada Y, Tokumasu M, Matsuo H, Yoshida K, Oki K, Yamato G, Hara Y, Kinoshita A, Tomizawa D, Taga T, Adachi S, Tawa A, Horibe K, Matsumoto N, Ito S, Hayashi Y, Shiba N
- Organizer
  61st American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Clinical Features of Pediatric Acute Myeloid Leukemia with TP53 and CDKN2A/2B copy Number Alterations.2019
- Author(s)
  Hara Y, Taki T, Yamato G, Yoshida K, Shiozawa Y, Shiba N, Kaburagi T, Shiraishi Y, Ohki K, Kawamura M, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Toki T, Kiyokawa N, Tomizawa D, Tago T, Ito E, Horibe K, Miyano S, Ogawa S, Adachi S, Hayashi Y
- Organizer
  61st American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] TP53遺伝子異常を伴う小児急性骨髄性白血病の臨床像と分子生物学異常の解析．2019
- Author(s)
  原　勇介，滝　智彦，大和玄季，吉田健一，柴　徳生，鏑木多映子，白石友一，大木健太郎，川村眞智子，外松　学，荒川浩一，松尾英将，嶋田　明，土岐　力，清河信敬，富澤大輔，多賀　崇，伊藤悦朗，堀部敬三，宮野　悟，小川誠司，足立壮一，林　泰秀
- Organizer
  第61回日本小児血液・がん学会
- Data Source
  KAKENHI-PROJECT-19K08350
[Presentation] Clinical significance and prognostic analyses of PTPN11, RAS, and CBL mutations in pediatric AML -the JCCG study, JPLSG AML05-2018
- Author(s)
  Taeko Kaburagi, Genki Yamato, Norio Shiba, Yusuke Hara, Kentaro Ohki, Manabu Sotomatsu, Hirokazu Arakawa, Nobutaka Kiyokawa, Daisuke Tomizawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Yasuhide Hayashi.
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] 4.Allogeneic bone marrow versus peripheral blood stem cell transplantation for hematological malignancies in children: systematic review and meta-analyses.2018
- Author(s)
  Yuko Shimosato-Wada, Reo Tanoshima, Shin-ichi Tsujimoto, Masanobu Takeuchi, Norio Shiba, Tohru Kobayashi, and Shuichi Ito.
- Organizer
  米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] 3.Comprehensive Analysis of 343 Genes using Targeted Sequencing Panel by Next-Generation Sequencer In 77 Pediatric AML Patients with Normal and Complex Karyotypes: JCCG Study, JPLSG AML-05.2018
- Author(s)
  Genki Yamato, Norio Shiba, Kenichi Yoshida, Yusuke Hara, Yuichi Shiraishi, Kentaro Ohki, Manabu Sotomatsu, Hirokazu Arakawa, Hidemasa Matsuo, Akira Shimada, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Keizo Horibe, Satoru Miyano, Seishi Ogawa, Souichi Adachi, Yasuhide Hayashi
- Organizer
  米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Prognosis of pediatric AML patient with FLT3-ITD is predicted by DNA methylation pattern; the JCCG study, JPLSG AML052018
- Author(s)
  Genki Yamato, Tomoko Kawai, Norio Shiba, Kentaro Ohki, Yusuke Hara, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Hirokazu Arakawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Kenichiro Hata, Yasuhide Hayashi.
- Organizer
  世界小児がん学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Clinical Features and Prognostic Impact of RUNX1 and PTPN11 Mutations in Pediatric Acute Myeloid Leukemia ;the JCCG study, -JPLSG AML-05-2017
- Author(s)
  Genki Yamato, Norio Shiba, Kenichi Yoshida, Yusuke Hara, et al.
- Organizer
  第59回米国血液学会（ASH）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Biology and Prognostic Markers in Young Children with Acute Myeloid Leukemia -the Jccg Study, JPLSG AML-05-2017
- Author(s)
  Yusuke Hara, Norio Shiba, Ken Tabuchi et al.
- Organizer
  第59回米国血液学会（ASH）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Comprehensive Methylation Analysis in Pediatric Patients with Acute Myeloid Leukemia.2017
- Author(s)
  enki Yamato, Tomoko Kawai, Norio Shiba, Kentaro Ohki, et al.
- Organizer
  第59回米国血液学会（ASH）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] RNA sequencing illustrates the genetic backgrounds of pediatric acute myeloid leukemia: the result of the JCCG study, JPLSG AML-052017
- Author(s)
  Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, et al.
- Organizer
  第59回米国血液学会（ASH）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Integrated genetic analysis using next generation sequencing in pediatric AML2016
- Author(s)
  柴　徳生
- Organizer
  第75回日本がん学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Identification of two distinct poor prognostic subgroups related to high expression of BMP2 or PRDM16 in pediatric AML2016
- Author(s)
  Hara Y, Yamato G, Shiba N, Okubo J, Ohki K, Park MJ, Sotomatsu M, Tomizawa D, Taki T, Kinoshita A, Kiyokawa N, Taga T, Arakawa H, Tawa A, Horibe K, Adachi S and Hayashi Y
- Organizer
  58th Annual Meeting of the American Society of Hematology（ASH)
- Place of Presentation
  San Diego
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Transcriptome Analysis Revealed the Entire Genetic Understanding of Pediatric Acute Myeloid Leukemia with a Normal Karyotype2016
- Author(s)
  Shiba N, Yoshida K, Shiraishi Y, Hara Y, Yamato G, Kaburagi K, Sanada M, Ohki K, Park MJ, Tomizawa D, Chiba K, Tanaka H, Sotomatsu M, Arakawa H, Horibe K, Taga T, Adachi S, Tawa A, Miyano S, Ogawa S and Hayashi Y.
- Organizer
  58th Annual Meeting of the American Society of Hematology（ASH)
- Place of Presentation
  San Diego
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] Retrospective Evaluation of Correlations Between Genetic Backgrounds and Stem Cell Transplantation for De Novo Pediatric Acute Myeloid Leukemia2016
- Author(s)
  Kaburagi T, Yamato G, Shiba N, Hara Y, Ohki K, Ichikawa H, Park MJ, Shimada A, Sotomatsu M, Arakawa H, Horibe K, Adachi S, Taga T, Tawa A, Hayashi Y
- Organizer
  58th Annual Meeting of the American Society of Hematology（ASH)
- Place of Presentation
  San Diego
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20951
[Presentation] 小児AMLにおける分子生物学的背景を用いた新たな治療層別化への試み2014
- Author(s)
  Norio Shiba et al.
- Organizer
  第117回日本小児科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] 全エクソーム解析による小児AML の新規原因遺伝子の同定2013
- Author(s)
  Norio Shiba et al.
- Organizer
  第55回日本小児血液がん学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] NUP98-NSD1 gene fusiontranslocation is a strong poor prognostic factor in pediatric AML2013
- Author(s)
  Yusuke Hara, Norio Shiba et al.
- Organizer
  The 45th International Society of Paediatric Oncology
- Place of Presentation
  香港
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] Whole-exome resequencing identifies somatic mutations of BCORL1 and major cohesin complex component genes in pediatric AML2013
- Author(s)
  Norio Shiba et al.
- Organizer
  第75回日本血液学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] Whole-Exome Resequencing Identifies Somatic Mutations of BCOR and BCORL1 Transcriptional Corepressor Genes and Major Cohesin Complex Component Genes in Pediatric AML2013
- Author(s)
  Norio Shiba et al.
- Organizer
  The 55th ASH
- Place of Presentation
  ニューオリンズ
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] Whole exome sequencing reveals spectrum of gene mutations in pediatric AML2012
- Author(s)
  Norio Shiba
- Organizer
  第54回米国血液学会
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] Whole exome resequencing reveals novel gene mutaions in pediatric AML2012
- Author(s)
  柴徳生
- Organizer
  第72回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] NUP98-NSD1 related gene expression signature is strongly associated with a poor prognosis in pediatric acute myeloid leukemia2012
- Author(s)
  Norio Shiba
- Organizer
  第54回米国血液学会
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] NUP98-NSD1 related gene expression signature is associated with a poor prognosis in pediatric AML2012
- Author(s)
  柴徳生
- Organizer
  第72回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] GATA2 mutations in pediatric acute myeloid leukemia2012
- Author(s)
  Norio Shiba
- Organizer
  第54回米国血液学会
- Place of Presentation
  アトランタ(米国)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] 発現アレイを用いた小児急性骨髄性白血病におけるNUP98-NSD1再構成関連群の解析2012
- Author(s)
  柴徳生
- Organizer
  第115回日本小児科学会
- Place of Presentation
  福岡
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] Identification of Scmatic Mutations in pediatric Acute Myeloid Leukeimia Using Whole-Exoroe Sequencing2012
- Author(s)
  柴徳生
- Organizer
  第54回日本小児血液学会
- Place of Presentation
  横浜
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] Identification of Somatic Mutations in pediatric Acute Myeloid Leukeimia Using Whole-Exome Sequencing2012
- Author(s)
  柴徳生
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] GATA2 mutations in pediatric acute myeloid leukemia2012
- Author(s)
  柴徳生
- Organizer
  第54回日本小児血液学会
- Place of Presentation
  横浜
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] 小児急性白血病におけるDNMT3A遺伝子変異の解析2011
- Author(s)
  柴徳生, 他
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 治療関連白血病と乳児白血病におけるCBL遺伝子変異の解析2011
- Author(s)
  柴徳生, 他
- Organizer
  第114回日本小児科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-08-13
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] CBL Mutation in Chronic Myelomonocytic Leukemia Secondary to Familial Platelet Disorder with Propensity to Develop Acute Myeloid Leukemia (FPD/AML)2011
- Author(s)
  Norio Shiba, Daisuke Hasegawa, Myoung-ja Park, Chisato Murata, Aiko Matsubara, Chitose Ogawa, Atsushi Manabe, Hirokazu Arakawa, Seishi Ogawa, and Yasuhide Hayashi
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋国際会議場、名古屋
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] NUP98-NSD1 Fusion Gene Is Strongly Associated with a Poor Prognosis in Pediatric Acute Myeloid Leukemia: A Study of the Japanese Childhood AML99 Cooperative Study Group2011
- Author(s)
  Norio Shiba, Tomohiko Taki, Myoung-ja Park, MD, Hitoshi Ichikawa, Manabu Sotomatsu, Souichi Adachi, Akio Tawa, Keizo Horibe, Hirokazu Arakawa, and Yasuhide Hayashi
- Organizer
  American Society of Hematology (ASH)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] CBL mutations in pediatric leukemia including therapy-related leukemia and infant leukemia2011
- Author(s)
  SHIBA Norio, TAKI Tomohiko, PARK Myoung-ja, and HAYASHI Yasuhide
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場、名古屋
- Data Source
  KAKENHI-PROJECT-23791151
[Presentation] CBL mutation in CMML secondary to familial platelet disorder with propensity to develop AML2011
- Author(s)
  Shiba N, et al
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] NUP98-NSD1 fusion gene is strongly associated with a poor prognosis in pediatric acute myeloid leukemia : a study of the Japanese Childhood AML99 Cooperative Study Group2011
- Author(s)
  Shiba N, et al
- Organizer
  53rd Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児急性骨髄性白血病におけるNUP98-NSD転座の解析2011
- Author(s)
  柴徳生, 他
- Organizer
  第53回日本小児血液・がん学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児白血病とMDSにおけるCBLとMPL遺伝子の解析2010
- Author(s)
  柴徳生, 他
- Organizer
  第7回北関東小児がんセミナー
- Place of Presentation
  高崎
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児急性白血病と骨髄異形成症候群におけるCBL遺伝子の解析2010
- Author(s)
  柴徳生, 朴明子, 林泰秀
- Organizer
  第114回小児血液腫瘍懇話会
- Place of Presentation
  東京
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 若年性骨髄単球性白血病におけるCBL遺伝子の解析2010
- Author(s)
  柴徳生, 他
- Organizer
  第113回日本小児科学会学術集会
- Place of Presentation
  岩手
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 治療関連白血病におけるCBLとRAS遺伝子の解析2010
- Author(s)
  柴徳生, 他
- Organizer
  第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] Mutation analyses of CBL and MPL genes in childhood leukemia and myelodysplastic syndrome.2010
- Author(s)
  Shiba N, et al.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] CBL mutations in therapy-related leukemia and infant leukemia.2010
- Author(s)
  Shiba N, et al.
- Organizer
  The 53rd ASH Annual Meeting and Exposition
- Place of Presentation
  Orlando, U.S.A.
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児悪性造血腫瘍におけるCBL遺伝子とMPL遺伝子の変異解析2010
- Author(s)
  柴徳生, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] PRDM16
- Author(s)
  Norio Shiba
- Organizer
  アメリカ血液学会（ASH）
- Place of Presentation
  サンフランシスコ
- Year and Date
  2014-12-09 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] 発現アレイを用いた小児急性骨髄性白血病における、NUP98-NSD1融合遺伝子の解析.
- Author(s)
  柴　徳生,　他
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児急性骨髄性白血病における分子生物学的背景を用いた新たな治療層別化への試み
- Author(s)
  柴　徳生
- Organizer
  日本小児科学会
- Place of Presentation
  広島
- Year and Date
  2014-04-13 – 2014-04-15
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] AML
- Author(s)
  Norio Shiba
- Organizer
  日本小児血液がん学会
- Place of Presentation
  岡山
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] 全エクソーム解析による小児急性骨髄性白血病の新規発症原因遺伝子変異の同定,
- Author(s)
  柴　徳生,　他
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] NUP98-NSD1 related gene expression signature is strongly associated with a poor prognosis in pediatric acute myeloid leukemia.,
- Author(s)
  Shiba N, et al.
- Organizer
  54rd Annual Meeting of the American Society of Hematology
- Place of Presentation
  Atlanta
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] Whole exome sequencing reveals spectrum of gene mutations in pediatric AML.
- Author(s)
  Shiba N, et al.
- Organizer
  54rd Annual Meeting of the American Society of Hematology
- Place of Presentation
  Atlanta
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 小児急性骨髄性白血病におけるGATA2遺伝子変異同定．
- Author(s)
  柴　徳生，他
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] NUP98-NSD1 related gene expression signature is associated with a poor prognosis in pediatric AML.
- Author(s)
  Shiba N, et al.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] Whole exome resequencing reveals novel gene mutations in pediatric AML.
- Author(s)
  Shiba N, et al.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] 全エクソーム解析による小児急性骨髄性白血病の新規発症原因遺伝子変異の同定
- Author(s)
  柴　徳生，他
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659196
[Presentation] AML
- Author(s)
  Norio Shiba
- Organizer
  日本血液学会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25893028
[Presentation] GATA2 mutations in pediatric acute myeloid leukemia: a study of the Japanese Childhood AML Cooperative Study Group.
- Author(s)
  Shiba N, et al.
- Organizer
  54rd Annual Meeting of the American Society of Hematology
- Place of Presentation
  Atlanta
- Data Source
  KAKENHI-PROJECT-22659196
[]

1. HAYASHI Yasuhide (30238133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. PARK Myoung-ja (50450375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. SANO Hirozumi (20469878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OHKI Kentaro (50400966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KAWAMURA Machiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. HARA YUSUKE

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. FUJII Yukihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. YAMADA Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. MURAMATSU Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SOTOMATSU Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 糸永英弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 足立壮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岡村浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 市川仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiba Norio 柴 徳生

SHIBA NORIO 柴 徳生

SHIBA Norio 柴 徳生

Research Projects

Research Products

Co-Researchers

PRDM16遺伝子高発現難治急性骨髄性白血病に対する分子標的薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenomic analysis in refractory AMLPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of molecular target of high risk pediatric AML by comprehensive genetic analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive genetic analysis of pediatric acute myeloid leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

乳児期を中心とした小児急性白血病と骨髄異形成症候群における新規原因遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome wide analysis of imprinting gene in pediatric solid tumor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Genome-wide DNA Methylation Analysis in Pediatric Acute Myeloid Leukemia.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Allogeneic Bone Marrow Transplantation versus Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies in Children: A Systematic Review and Meta-Analysis.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A 2‐year‐old patient with a diffuse intrinsic pontine glioma and radiation‐induced moyamoya syndrome.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The outcomes of relapsed acute myeloid leukemia in children: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group AML‐05R study.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Patients aged less than 3 years with acute myeloid leukaemia characterize a molecularly and clinically distinct subgroup.2020

Author(s)

Journal Title

Shiba Norio 柴徳生

SHIBA NORIO 柴徳生

SHIBA Norio 柴徳生