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Kaito Tomoko  藤幸 知子

… Alternative Names

Fujiyuki Tomoko  藤幸 知子

垣内 知子  カイト トモコ

藤幸知子

FUJIYUKI Tomoko  藤幸 知子

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Researcher Number 50610630
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5533-4129
Affiliation (Current) 2025: 帝京大学, 先端総合研究機構, 准教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 東京大学, 生産技術研究所, 特任准教授
2019: 東京大学, 生産技術研究所, 主任研究員
2018: 東京大学, 生産技術研究所, 特任准教授
2014 – 2018: 東京大学, 医科学研究所, 助教
2012: 東京大学, 医科学研究所, 助教
2011: 東京大学, 医科学研究所, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Virology / Tumor therapeutics
Except Principal Investigator
Medium-sized Section 49:Pathology, infection/immunology, and related fields / Nanomaterials/Nanobioscience
Keywords
Principal Investigator
麻疹ウイルス / 細胞死 / 腫瘍溶解性ウイルス / 免疫誘導性細胞死 / がん / 免疫誘導 / がん治療 / 免疫応答 / nectin-4 / Nectin-4 … More / 癌治療 / 抵抗性 / 投与経路 / 組換え麻疹ウイルス / 抗腫瘍効果 / 難治性癌 / 腫瘍溶解性麻疹ウイルス / 難治性乳癌 / H5N1 / ウイルスベクター / 組換えウイルス / ベクター / ワクチン / 発症防御 / 感染モデル / カニクイザル / 高病原性鳥インフルエンザウイルス / 輸送 / 細胞内輸送 / 糖タンパク質 / 細胞内局在 / 膜タンパク質 / ニパウイルス … More
Except Principal Investigator
ニパウイルス / 野外迅速診断法 / 疫学調査 / 迅速診断法 / AMCA培養系 / 神経細胞 / 個体内伝播 / 細胞内局在 / 病原性 / アクセサリー蛋白 / 膜たんぱく / 麻疹ウイルス / 細胞 Less
  • Research Projects

    (7 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (14 People)
  •  癌治療用組換え麻疹ウイルスによる細胞死メカニズムと免疫誘導性の解析Principal Investigator

    • Principal Investigator
      藤幸 知子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      The University of Tokyo
  •  ニパウイルスの野外迅速診断法確立とこれを用いた流行地域におけるウイルス性状の解析

    • Principal Investigator
      米田 美佐子
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      The University of Tokyo
  •  Cell death mechanisms induced by infection with oncolytic measles virusPrincipal Investigator

    • Principal Investigator
      Fujiyuki Tomoko
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      The University of Tokyo
  •  Molecular basis underlying anti-tumor activity of an oncolytic measles virusPrincipal Investigator

    • Principal Investigator
      Fujiyuki Tomoko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      The University of Tokyo
  •  Development of measles virus vector-based vaccine against highly pathogenic avian influenza virusPrincipal Investigator

    • Principal Investigator
      Fujiyuki Tomoko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  Analysis of intracellular trafficking of membrane proteins of Nipah virusPrincipal Investigator

    • Principal Investigator
      FUJIYUKI Tomoko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  Analysis of propagation manners of paramyxoviruses in neural cells.

    • Principal Investigator
      YONEDA Misako
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      The University of Tokyo

All 2019 2018 2017 2016 2015 2014 2012 2011 Other

All Journal Article Presentation Other

  • [Journal Article] Measles virus selectively blind to SLAM has oncolytic efficacy against nectin-4-expressing pancreatic cancer cells.2016

    • Author(s)
      Awano M, Fujiyuki T, Shoji K, Amagai Y, Murakami Y, Furukawa Y, Sato H, Yoneda M, Kai C
    • Journal Title

      Cancer Sci

      Volume: 11 Issue: 11 Pages: 1647-1652

    • DOI

      10.1111/cas.13064

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16J10993, KAKENHI-PROJECT-16H02587, KAKENHI-PROJECT-16K20991
  • [Journal Article] Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay2012

    • Author(s)
      Fujiyuki T, Hamamoto H, Ishii K, Urai M, Kataoka K, Takeda T, Shibata S, Sekimizu K
    • Journal Title

      Drug Discoveries and Therapeutics

      Volume: 6 Pages: 88-93

    • NAID

      130005054745

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890038
  • [Journal Article] Evidence of a novel immune responsive protein in the Hymenoptera2011

    • Author(s)
      Albert S, Gatschenberger H, Azzami K, Gimple O, Grimmer G, Sumner S, Fujiyuki T, Tautz J, Mueller MJ
    • Journal Title

      Insect Biochemistry and Molecular Biology

      Volume: 41 Pages: 968-981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890038
  • [Presentation] 正常免疫腫瘍モデルを用いた腫瘍溶解性組み換え麻疹ウイルス療法における免疫反応の評価2019

    • Author(s)
      森藤可南子、庄司紘一郎、雨貝陽介、藤幸知子、佐藤宏樹、米田美佐子、甲斐知惠子
    • Organizer
      第67回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] 犬の原発性肺腺癌細胞における腫瘍溶解性組み替え麻疹ウイルスの抗腫瘍効果2019

    • Author(s)
      田村啓、藤幸知子、森藤可南子、飯塚恵悟、佐藤宏樹、浅野和之、米田美佐子、甲斐知惠子
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] 癌細胞における Raf/MAPK 経路の活性化が腫瘍溶解性組換え麻疹 ウイルスの増殖を促進する2019

    • Author(s)
      藤幸知子、庄司紘一郎、佐藤宏樹、米田美佐子、甲斐知惠子
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] 正常免疫マウス腫瘍モデルを用いた組み換え麻疹ウイルス療法における免疫反応の解析2019

    • Author(s)
      森藤可南子、庄司紘一郎、雨貝陽介、藤幸知子、佐藤宏樹、米田美佐子、甲斐知惠子
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] A recombinant measles virus blind to SLAM is a promising candidate for scirrhous gastric cancer therapy.2018

    • Author(s)
      Kai C, Shoji K, Kwon HJ, Sugai A, Yanagihara K, Yamaguchi H, Sato H, Fujiyuki T, Yoneda M.
    • Organizer
      XIX International meeting on Negative strand viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Oncolytic recombinant measles is a candidate therapeutic agent for refractory breast cancer.2018

    • Author(s)
      Fujiyuki T, Amagai Y, Shoji K, Sugai A, Awano M, Sato H, Yoneda M, Kai C.
    • Organizer
      XIX International meeting on Negative strand viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Anti-tumor acitivity of a recombinant oncolytic measles virus, rMV-SLAMblind, against scirrhous gastric cancer cells.2018

    • Author(s)
      Kai C, Shoji K, Kwon HJ, Sugai A, Yanagihara K, Yamaguchi H, Nakanishi T, Sato H, Fujiyuki T, Yoneda M.
    • Organizer
      第66回日本ウイルス学会
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Antitumor effects of a recombinant SLAM-blind measles virus in immunocompetent murine model.2018

    • Author(s)
      Shoji K, Fujiyuki T, Amagai Y, Yoneda M, Sato H, Kai C.
    • Organizer
      11th International Oncolytic Virus Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] A recombinant SLAMblind measles virus is applicable for breast cancer treatment.2018

    • Author(s)
      Yoneda M, Fujiyuki T, Sato H, Daigo Y, Kai C.
    • Organizer
      11th International Oncolytic Virus Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] A recombinant SLAM-blind measles virus is a promising candidate for scirrhous gastric cancer treatment.2018

    • Author(s)
      Kai C, Shoji K, Kwon HJ, Sugai A, Yanagihara K, Yamaguchi H, Sato H, Fujiyuki T, Yoneda M.
    • Organizer
      11th International Oncolytic Virus Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Influence of anti-measles virus immunity on recombinant measles virus therapy for cancer in immunocompetent tumor model.2018

    • Author(s)
      Shoji K, Moritoh K, Amagai Y, Fujiyuki T, Sato H, Yoneda M, Kai C.
    • Organizer
      第66回日本ウイルス学会
    • Data Source
      KAKENHI-PROJECT-18K07291
  • [Presentation] Development of oncolytic measles virus, rMV-SLAMblind.2017

    • Author(s)
      Kai C, Fujiyuki T, Shoji K, Sato H, Yoneda M.
    • Organizer
      XXVth European Society of Gene & Cell Therapy, Oct 17-21, Berlin, Germany.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 正常免疫マウス腫瘍モデルを用いた組換え麻疹ウイルスの抗腫瘍効果 に対する抗体の影響2017

    • Author(s)
      庄司 紘一郎、雨貝 陽介、藤幸 知子、佐藤 宏樹、米田 美佐子、甲斐 知惠子
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 組換え麻疹ウイルスのスキルス胃癌細胞株に対する抗腫瘍効果2017

    • Author(s)
      藤幸 知子、庄司 紘一郎、菅井 亮宏、山口 英樹、柳原 五吉、 佐藤 宏樹、米田 美佐子、甲斐 知惠子
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] An oncolytic recombinant measles virus is a candidate of a novel therapeutic agent for triple negative breast cancer.2017

    • Author(s)
      Fujiyuki T, Amagai Y, Shoji K, Sugai A, Awano M, Sato H, Yoneda M, Kai C.
    • Organizer
      XXVth European Society of Gene & Cell Therapy, Oct 17-21, Berlin, Germany.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 正常免疫腫瘍移植モデルを用いた組換え麻疹ウイルスの治療効果および免疫の影響2017

    • Author(s)
      庄司紘一郎、藤幸知子、雨貝陽介、佐藤宏樹、米田美佐子、甲斐知惠子
    • Organizer
      第160回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Recombinant SLAM-blind measles virus is a promising candidate for triple negative breast cancer therapy.2016

    • Author(s)
      Fujiyuki T, Amagai Y, Shoji K, Kuraishi T, Sugai A, Awano M, Sato H, Hattori S, Yoneda M, Kai C.
    • Organizer
      第64回日本ウイルス学会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 腫瘍溶解性組換え麻疹ウイルスの難治性乳癌細胞に対する抗腫瘍効果2016

    • Author(s)
      藤幸知子、雨貝陽介、庄司紘一郎、菅井亮宏、粟野睦美、佐藤宏樹、米田美佐子、甲斐知惠子
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 麻疹ウイルスベクターを利用した高病原性鳥インフルエンザウイルスワクチンの霊長類感染モデルにおける効果2016

    • Author(s)
      藤幸知子、堀江亮、米田美佐子、倉石武、安井文彦、権賢貞、池田房子、宗片圭祐、石井美穂、木曽有里、佐藤宏樹、服部正策、喜田宏、小原道法、甲斐知恵子
    • Organizer
      第63回日本実験動物学会
    • Place of Presentation
      川崎
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26870147
  • [Presentation] Immunocompetent animal model to examine influence of immunity on oncolytic virotherapy with a recombinant measles virus.2016

    • Author(s)
      Shoji K, Fujiyuki T, Amagai Y, Sato H, Yoneda M, Kai C.
    • Organizer
      International Veterinary Immunology Symposium 2016
    • Place of Presentation
      ゴールドコースト(オーストラリア)
    • Year and Date
      2016-08-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] 癌幹細胞様サイドポピュレーションに対する腫瘍溶解性組換え麻疹ウイルスの抗腫瘍効果解析2016

    • Author(s)
      Awano M, Fujiyuki T, Shoji K, Yoneda M, Kai C.
    • Organizer
      第75回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K20991
  • [Presentation] Efficacy of recombinant measles virus expressing highly pathogenic avian influenza virus antigen in non-human primate model2015

    • Author(s)
      Tomoko Fujiyuki, Ryo Horie, Misako Yoneda, Takeshi Kuraishim Fumihiko Yasui, Hyun-jeoung Kwon, Fusako Ikeda, Keisuke Munekata, Miho Ishii, Yuri Kiso, Mio Omi, Hiroki Sato, Hiroshi Kida, Shosaku Hattori, Michinori Kohara, Chieko Kai.
    • Organizer
      第63回日本ウイルス学会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26870147
  • [Presentation] Macaque models of highly pathogenic avian influenza virus infection using a wild water bird-derived strain.2014

    • Author(s)
      Tomoko Fujiyuki, Misako Yoneda, Fumihiko Yasui, Takeshi Kuraishi, Shosaku Hattori, Hyun-jeong Kwon, Keisuike Munekata, Yuri Kiso, Hiroshi Kida, Michinori Kohara, Chieko Kai.
    • Organizer
      第14回東京大学生命科学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-04-26
    • Data Source
      KAKENHI-PROJECT-26870147
  • [Presentation] H5N1高病原性鳥インフルエンザ組換えワクチニアワクチン単回接種による免疫長期持続作用機序の解析2014

    • Author(s)
      安井文彦、宗片圭祐、倉石武、服部正策、藤幸知子、米田美佐子、迫田義博、喜田宏、甲斐知恵子、小原道法
    • Organizer
      第62回日本ウイルス学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10
    • Data Source
      KAKENHI-PROJECT-26870147
  • [Presentation] 日本の野鳥由来高病原性鳥インフルエンザウイルスの霊長類への感染2012

    • Author(s)
      藤幸知子、米田美佐子、安井文彦、倉石武、服部正策、権賢貞、宗片圭祐、木曽有里、喜田宏、小原道法、甲斐知恵子
    • Organizer
      第60回日本ウイルス学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23890038
  • [Presentation] Discriminative survey of distribution of Kakugo virus and deformed wing virus in honeybee (Apis mellifera carnica) colonies in Germany2011

    • Author(s)
      Fujiyuki T, Beier H, Azzami K, Tautz J, Kubo T
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23890038
  • [Presentation] Attenuated recombinant measles virus expressing highly pathogenic avian influenza virus (HPAIV) antigen is protective against HPAIV challenge in cynomolgus monkeys

    • Author(s)
      Tomoko Fujiyuki, Ryo Horie, Misako Yoneda, Takeshi Kuraishi, Fumihiko Yasui, Keisuke Munekata, Shosaku Hattori, Hiroshi Kida, Michinori Kohara, Chieko Kai.
    • Organizer
      XVIth International Congress of Virology
    • Place of Presentation
      カナダ、モントリオール
    • Year and Date
      2014-07-27 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-26870147
  • [Presentation] 霊長類感染モデルを用いた高病原性鳥インフルエンザウイルス抗原発現組換え麻疹ウイルスの防御効果の解析

    • Author(s)
      藤幸知子、堀江亮、米田美佐子、倉石武、安井文彦、宗片圭祐、池田房子、木曽有里、権賢貞、石井美穂、佐藤宏樹、服部正策、喜田宏、小原道法、甲斐知恵子
    • Organizer
      第61回日本実験動物学会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26870147
  • []

  • 1.  YONEDA Misako (40361620)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 20 results
  • 2.  KAI Chieko (10167330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 3.  OMI Mio (00526767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  YASUDA Kenji (20313158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KOHARA Michinori (10250218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  KIDA Hiroshi (10109506)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 7.  HATTORI Shosaku (00164864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  竹内 円雅 (80887711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  沈 秀珍 (70905942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  佐々木 由比 (00913922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  朴 成和 (50505948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  森藤 可南子 (90867524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  佐藤 宏樹 (50418654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  甲斐 知恵子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results

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