Koyama Keisuke 古山敬祐

Researcher Number	50611026
Other IDs	https://orcid.org/0000-0002-5946-2301
Affiliation (Current)	2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help	2024: 大阪公立大学, 大学院獣医学研究科, 准教授 2022: 大阪公立大学, 大学院獣医学研究科, 准教授 2019 – 2021: 大阪府立大学, 生命環境科学研究科, 講師 2018 – 2020: 地方独立行政法人北海道立総合研究機構, 農業研究本部酪農試験場, 研究職員 2018: 地方独立行政法人北海道立総合研究機構, 農業研究本部酪農試験場, 研究主任 2016 – 2017: 地方独立行政法人北海道立総合研究機構, 農業研究本部根釧農業試験場, 研究主任 2016 – 2017: 地方独立行政法人北海道立総合研究機構, 農業研究本部根釧農業試験場, 研究職員
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Animal production science Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Basic Section 61030:Intelligent informatics-related / Animal production science / Veterinary medical science
Keywords	Principal Investigator 牛 / 核成熟 / 機械学習 / 卵子 / 画像解析 / 着床能力 / 卵割動態 / 発生能 / ウシ卵子 / 体外受精 … More / 個別培養 / 成熟培養 / 受精卵 / 繁殖 / 卵胞数 / 卵巣予備能 / テストステロン / 妊娠期 / AMH / AFC / 繁殖性 / 妊娠 / 乳牛 / 飼養管理 / 血液生化学性状 … More Except Principal Investigator 精子 / INSL3 / 乳牛 / ウシ / 胚 / 卵子 / 受容体 / 生殖細胞 / 生殖器 / 蛍光免疫測定法 / 卵胞嚢腫 / 黄体 / 雌ウシ / INSL3受容体（RXFP2） / 卵胞 / 超音波画像検査 / 成長 / 黒毛和種雌ウシ / サンドイッチ時間分解蛍光免疫測定 / 発情発見 / 視覚化 / 繁殖 / 帰納学習 / 機械学習 / 潜在性ルーメンアシドーシス / ルーメン（第一胃） / 濃厚飼料多給 / 肝機能 / 繁殖機能 / エンドトキシン / ルーメン / 胎盤 / 炎症 / 分娩誘起 / 胎盤停滞 / 分娩 / 牛 Less

Elucidation of roles and signal transduction of INSL3 in bovine gamate maturaiton, fertilization and embryo development
- Principal Investigator
  
  川手憲俊
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
Establishment of a bovine embryo production system with high implantation competence using an artificial intelligence-based nuclear maturation speed prediction modelPrincipal Investigator
- Principal Investigator
  
  古山敬祐
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
Studies on expressions and roles of INSL3 secretory dynamics and its receptor expression in reproductive organs and germ cells in female cattle
- Principal Investigator
  
  川手憲俊
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Establishment of in vitro culture system of bovine oocyte corresponding to the speed of nuclear maturation for production of the embryo with high implantation abilityPrincipal Investigator
- Principal Investigator
  
  Koyama Keisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Developing algorithm for estrus detection based on social relationships between cows
- Principal Investigator
  
  OHWADA Hayato
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 61030:Intelligent informatics-related
- Research Institution
  Tokyo University of Science
Elucidation of factors that impair reproductive function and improvement of metabolic function due to subacute rumen acidosis in dairy cows
- Principal Investigator
  
  OHTAKI Tadatoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Nihon University
Induction of placental maturation at induced parturiton in cows
- Principal Investigator
  
  HIRAYAMA Hiroki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Tokyo University of Agriculture
Study on the mechanism for diminishing fetal ovarian reserve mediated by maternal testosteronePrincipal Investigator
- Principal Investigator
  
  Koyama Keisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Animal production science
- Research Institution
  Hokkaido Research Organization

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Expression of C–C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition2020
- Author(s)
  Hirayama, H., Sakumoto, R., Koyama, K., Yasuhara, T., Hasegawa, T., Inaba, R., Fujii, T., Naito, A., Moriyasu, S., & Kageyama, S.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 66 Issue: 1 Pages: 49-55
- DOI
  10.1262/jrd.2019-113
- NAID
  130007798074
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05040
[Journal Article] Enhanced glucocorticoid exposure facilitates the expression of genes involved in prostaglandin and estrogen syntheses in bovine placentomes at induced parturition.2019
- Author(s)
  Yasuhara, T., Koyama, K., Sakumoto, R., Fujii, T., Naito, A., Moriyasu, S., Kageyama, S., & Hirayama, H.
- Journal Title
  
  Theriogenology
  
  Volume: 139 Pages: 1-7
- DOI
  10.1016/j.theriogenology.2019.07.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05040
[Journal Article] Repeatability of antral follicle count according parity in dairy cows2018
- Author(s)
  KOYAMA Keisuke、KOYAMA Takeshi、SUGIMOTO Masahito
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 6 Pages: 535-539
- DOI
  10.1262/jrd.2018-062
- NAID
  130007530490
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18787
[Presentation] 粗飼料多給飼養環境下の乳牛における分娩後ルーメン内LPS濃度の変動と繁殖成績との関連性2019
- Author(s)
  大矢琴美, 大滝忠利, 古山敬祐, 梶川博, 住吉俊亮, 浅野早苗, 堀北哲也
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08052
[Presentation] ホルスタイン種未経産牛の妊娠中血中テストステロン濃度と産子の卵巣予備能および母体の健康状態との関連性2018
- Author(s)
  古山敬祐, 柳川洋二郎, 小山毅, 窪友瑛, 杉本昌仁
- Organizer
  日本獣医学会
- Data Source
  KAKENHI-PROJECT-16K18787
[Presentation] ウシ分娩時胎盤節における主要組織適合遺伝子複合体クラス1（BoLA-1）発現2018
- Author(s)
  泰原大治・古山敬祐・作本亮介・小林祐子・平山博樹
- Organizer
  第111回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-16H05040
[Presentation] 乳牛のグルココルチコイドによる誘起分娩時胎盤節のプロスタグランジン合成酵素発現2018
- Author(s)
  泰原大治・古山敬祐・作本亮介・平山博樹
- Organizer
  日本畜産学会第124回大会
- Data Source
  KAKENHI-PROJECT-16H05040
[Presentation] Difference in antral follicle count of daughters and testosterone concentration during pregnancy between heifers and lactating cows2017
- Author(s)
  Keisuke Koyama, Yojiro Yanagawa, Takeshi Koyama, Yoshitaka Matsui, Naohito Kusakari, Masahito Sugimoto
- Organizer
  Fourth World Congress of Reproductive Biology
- Place of Presentation
  沖縄
- Year and Date
  2017-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18787
[Presentation] ホルスタイン種泌乳牛における初産次以降のAntral follicle countの再現性2017
- Author(s)
  古山敬祐・小山毅・松井義貴・草刈直仁・杉本昌仁
- Organizer
  平成28年度日本獣医師会獣医学術学会年次大会（石川）
- Place of Presentation
  石川
- Year and Date
  2017-02-24
- Data Source
  KAKENHI-PROJECT-16K18787
[Presentation] Expression of CC chemokines and their receptors in bovine placentome at spontaneous and induced parturition2017
- Author(s)
  Hiroki Hirayama, Ryosuke Sakumoto, Keisuke Koyama, Taichi Yasuhara, Taito Hasegawa, Takashi Fujii, Satoru Moriyasu
- Organizer
  Fourth World Congress of Reproductive Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05040
[Presentation] グルココルチコイドによる誘起分娩がウシ胎盤節におけるプロスタグランジン合成酵素発現に及ぼす影響2017
- Author(s)
  平山博樹・泰原大治・古山敬祐・作本亮介・藤井貴志・森安悟
- Organizer
  日本畜産学会第122回大会
- Place of Presentation
  神戸大学（神戸市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16H05040

1. HIRAYAMA Hiroki (60390861)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 川手憲俊 (80221901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 原山洋 (30281140)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OHTAKI Tadatoshi (10434101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. OHWADA Hayato (30203954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 梶川博 (90414705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 堂腰顕 (40506606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 窪友瑛 (50825338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大島一郎 (60465466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鍋西久 (90575151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 西村亮 (20704901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Yanagawa Yojiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Koyama Keisuke 古山 敬祐

Research Projects

Research Products

Co-Researchers

Elucidation of roles and signal transduction of INSL3 in bovine gamate maturaiton, fertilization and embryo development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a bovine embryo production system with high implantation competence using an artificial intelligence-based nuclear maturation speed prediction modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on expressions and roles of INSL3 secretory dynamics and its receptor expression in reproductive organs and germ cells in female cattle

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of in vitro culture system of bovine oocyte corresponding to the speed of nuclear maturation for production of the embryo with high implantation abilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing algorithm for estrus detection based on social relationships between cows

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of factors that impair reproductive function and improvement of metabolic function due to subacute rumen acidosis in dairy cows

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of placental maturation at induced parturiton in cows

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism for diminishing fetal ovarian reserve mediated by maternal testosteronePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of C–C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Enhanced glucocorticoid exposure facilitates the expression of genes involved in prostaglandin and estrogen syntheses in bovine placentomes at induced parturition.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repeatability of antral follicle count according parity in dairy cows2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] 粗飼料多給飼養環境下の乳牛における分娩後ルーメン内LPS濃度の変動と繁殖成績との関連 性2019

Author(s)

Organizer

Data Source

[Presentation] ホルスタイン種未経産牛の妊娠中血中テストステロン濃度と産子の卵巣予備能および母体の健康状態との関連性2018

Author(s)

Organizer

Koyama Keisuke 古山敬祐

[Presentation] 粗飼料多給飼養環境下の乳牛における分娩後ルーメン内LPS濃度の変動と繁殖成績との関連性2019