Kuwayama Kazuyuki 桑山一行

… Alternative Names

KUWAYAMA Kauyuki 桑山一行

Less

Researcher Number	50614236
Affiliation (Current)	2025: 独立行政法人国立病院機構四国こどもとおとなの医療センター(臨床研究部(成育)、臨床研究部(循環器)), 臨床研究部, 脳神経外科医長
Affiliation (based on the past Project Information) *help	2017: 徳島大学, 大学病院, 非常勤講師 2015 – 2016: 独立行政法人国立病院機構四国こどもとおとなの医療センター(臨床研究部(成育)、臨, 臨床研究部, 脳神経外科医長 2015: 徳島大学, 大学病院, 非常勤講師 2015: 四国こどもとおとなの医療センター, 臨床研究部, 脳神経外科医長 2014: 徳島大学, 病院, 講師 2013 – 2014: 徳島大学, 大学病院, 講師
Review Section/Research Field	Principal Investigator Neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator エストロゲン受容体作動薬（SERM） / エストロゲン受容体作動薬(SERM） / 脳動脈瘤破裂 / エストロゲン受容体調節薬 / エストロゲン受容体α/β / 脳血管病 Except Principal Investigator 高血圧 / 血行動態変化 / 脳動脈瘤破裂 / エストロゲン … More / 脳血管病 / 脳・神経 / 脳動脈瘤破裂　血行動態変化 / 歯周病 / 脳動脈瘤 / エストロゲン受容体調整薬 / Wntシグナル / Ad-REIC / 悪性脳腫瘍 / ｸﾞﾘｵﾌﾞﾗｽﾄｰﾏ / 遺伝子治療 / DKK3 / Wnt / グリオブラストーマ / 脳腫瘍 / 高塩食 / 破裂脳動脈瘤 / くも膜下出血 / 脳血管障害 / 結構動態変化 Less

Early diagnosis and pharmacological treatment to prevent the rupture of cerebral aneurysms
- Principal Investigator
  
  NAGAHIRO Shinji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima
Role of selective estrogen receptor modulators on cerebrovascular diseasesPrincipal Investigator
- Principal Investigator
  
  Kuwayama Kazuyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  独立行政法人国立病院機構四国こどもとおとなの医療センター(臨床研究部(成育)、臨床研究部(循環器))
  The University of Tokushima
Anti-tumor effects and Regulation of Wnt signaling pathway of adenovirus-mediated DKK3 in glioblastoma
- Principal Investigator
  
  MIZOBUCHI Yoshifumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima
Molecular mechanisms underlying the rupture of cerebral aneurysms and the pharmacological regulation
- Principal Investigator
  
  NAGAHIRO Shinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokushima

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study2018
- Author(s)
  1.Nagahiro S, Tada Y, Satomi J, Kinouchi T, Kuwayama K, Yagi K, Nakajima K, Matsushita N, Miyamoto T, Yamaguchi T, Shimada K, Korai M, Mure H, Okayama Y, Abe T, Harada M, Kitazato KT, Kanematsu Y
- Journal Title
  
  Stroke Cerebrovasc Dis
  
  Volume: - Issue: 8 Pages: 2134-2140
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.03.008
- NAID
  120006961144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10831, KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-17K10832, KAKENHI-PROJECT-18K16562
[Journal Article] Treatment Outcome of Carotid Artery Stenting Underwent within 14 Days of Stroke Onset – Consideration of Safety and Efficacy of Urgent Carotid Artery Stenting for Neurologically Progressing Patients2017
- Author(s)
  Kanematsu Y, Satomi J, Kuwayama K, Yamaguchi I, Yoshioka S, Kinouchi T, Tada Y, Yamamoto N, Matsubara S, Satoh K, Nagahiro S
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 57 Issue: 6 Pages: 278-283
- DOI
  10.2176/nmc.oa.2016-0236
- NAID
  130006882460
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-17K10832
[Journal Article] Pulsatile Tinnitus due to an Aberrant Internal Carotid Artery in the Middle Ear:A Case Report2017
- Author(s)
  Kuwayama K, Satomi J, Yamaguchi T, Yamaguchi I, Sogabe S, Yoshioka S, Nagahiro S
- Journal Title
  
  Neurological Surgery 脳神経外科
  
  Volume: 45 Issue: 4 Pages: 321-324
- DOI
  10.11477/mf.1436203502
- ISSN
  0301-2603, 1882-1251
- Year and Date
  2017-04-10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04950
[Journal Article] Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment2017
- Author(s)
  Sogabe S, Satomi J, Tada Y, Kanematsu Y, Kuwayama K, Yagi K, Yoshioka S, Mizobuchi Y, Mure H, Yamaguchi I, Abe T, Yamamoto N, Kitazato KT, Kaji R, Harada M, Nagahiro S
- Journal Title
  
  Neuroradiology.
  
  Volume: － Issue: 6 Pages: 587-595
- DOI
  10.1007/s00234-017-1828-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-16K10788, KAKENHI-PROJECT-17K10832, KAKENHI-PROJECT-15K10305
[Journal Article] PPARγ-Dependent and -Independent Inhibition of the HMGB1/TLR9 Pathway by Eicosapentaenoic Acid Attenuates Ischemic Brain Damage in Ovariectomized Rats2015
- Author(s)
  Sumiyoshi M, Satomi J, Kitazato KT, Yagi K, Shimada K, Kurashiki Y, Korai M, Miyamoto T, Suzue R, Kuwayama K, Nagahiro S
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 24 Issue: 6 Pages: 1187-1195
- DOI
  10.1016/j.jstrokecerebrovasdis.2015.01.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] Improvement of plasma biomarkers including angiotensin-(1-7) after switching from other angiotensin II type I receptor blockers to olmesartan in stroke patients with insufficient blood pressure control2015
- Author(s)
  Tada Y, Yagi K, Uno M, Matsushita N, Kanematsu Y, Kuwayama K, Shimada K, Nishi K, Hirasawa M, Satomi, J, Kitazato, K, Kageji T, Matsuura E, Nagahiro S
- Journal Title
  
  J stroke cerebrovasc dis
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462159
[Journal Article] Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma2015
- Author(s)
  Hara K, Kageji T, Mizobuchi Y, Kitazato KT, Okazaki T, Fujihara T, Nakajima K, Mure H, Kuwayama K, Hara T, Nagahiro S
- Journal Title
  
  Cancer Lett
  
  Volume: 356 Issue: 2 Pages: 496-505
- DOI
  10.1016/j.canlet.2014.09.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462264, KAKENHI-PROJECT-26861153
[Journal Article] The accumulation of brain water-free sodium is associated with ischemic damage independent of the blood pressure in female rats2015
- Author(s)
  Sumiyoshi M, Kitazato KT, Yagi K, Miyamoto T, Kurashiki Y, Matsushita N, Kinouchi T, Kuwayama K, Satomi J, Nagahiro S
- Journal Title
  
  Brain Res
  
  Volume: 1616 Pages: 37-44
- DOI
  10.1016/j.brainres.2015.04.051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan2015
- Author(s)
  Tada Y, Yagi K, Uno M, Matsushita N, Kanematsu Y, Kuwayama K, Shimada K, Nishi K, Hirasawa M, Satomi J, Kitazato KT, Kageji T, Matsuura E, Nagahiro S
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 24 Issue: 7 Pages: 1487-1492
- DOI
  10.1016/j.jstrokecerebrovasdis.2015.03.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15H04950
[Journal Article] Intra-arterial signal on arterial spin labeling perfusion MRI to identify the presence of acute middle cerebral artery occlusion2014
- Author(s)
  Tada Y, Satomi J, Abe T, Kuwayama K, Sogabe S, Fujita K, Yamamoto N, Kaji R, Harada M, Nagahiro S
- Journal Title
  
  Cerebrovasc Dis
  
  Volume: 38 Pages: 191-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462159
[Presentation] Impact of Periodontal Disease and －Bacteria on Intracranial Aneurysms2016
- Author(s)
  S. Yoshioka, Y. Tada, J. Satomi, K. Yagi, K. Naruishi, K. Kuwayama, K. T. Kitazato, T. Miyamoto, Y. Kanematsu, M. Harada, T. Nagata, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462159
[Presentation] A Pilot Study of the Mineralocorticoid Receptor Blocker Eplerenone in Hypertensive Patients with Unruptured Cerebral Aneurysms2016
- Author(s)
  J. Satomi, Y. Tada, Y. Kanematsu, K. Kuwayama, K. Yagi, T. Kinouchi, K. Nakajima, N. Matsushita, T. Miyamoto, T. Yamaguchi, M. Korai, H. Mure, K. T. Kitazato, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Impact of Periodontal Disease and －Bacteria on Intracranial Aneurysms2016
- Author(s)
  S. Yoshioka, Y. Tada, J. Satomi, K. Yagi, K. Naruishi, K. Kuwayama, K. T. Kitazato, T. Miyamoto, Y. Kanematsu, M. Harada, T. Nagata, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] A Pilot Study of the Mineralocorticoid Receptor Blocker Eplerenone in Hypertensive Patients with Unruptured Cerebral Aneurysms2016
- Author(s)
  J. Satomi, Y. Tada, Y. Kanematsu, K. Kuwayama, K. Yagi, T. Kinouchi, K. Nakajima, N. Matsushita, T. Miyamoto, T. Yamaguchi, M. Korai, H. Mure, K. T. Kitazato, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462159
[Presentation] Down-regulation of MDR1 by DKK3 attenuates chemoresistance to temozolomide, and potentiates its anti-tumor effects2015
- Author(s)
  T.Fujihara, T.Kageji, Y.Mizobuchi, R.Otsuka K.Kitazato, K.Hara, K.Shono, K.Nakajima H.Mure, K.Kuwayama, S.Nagahiro
- Organizer
  20th Annual Socientific Meeting and Education Day of the Society for Neuro-Oncology
- Place of Presentation
  Texas, USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Sonodynamic 5-ALA plus ultrasound therapy augments anti-tumor effects in the oncogene knock-in glioma stemcells2015
- Author(s)
  K.Shono, T.Kageji, Y.Mizobuchi, T.Fujihara, K.Kitazato, K.Nakajima, H.Mure, K.Kuwayama, S.Nagahiro
- Organizer
  20th Annual Socientific Meeting and Education Day of the Society for Neuro-Oncology,
- Place of Presentation
  Texas,USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] A combination of interferon-b and temozolomide augments anti-tumor effects through p73/YAP-mediated apoptosis by PML in glioblastoma2013
- Author(s)
  Y.Mizobuchi, T.Okazaki, T.Kageji, K.Kuwayama, K.T.Kitazato, H.Mure, K.Hara, R.Morigaki, K.Matsuzaki, K.Nakajima, T.Fujihara, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Down-regulation of MDR by Ad-Dkk3 contributes to augment the chemotherapy by temozolomide2013
- Author(s)
  K.Nakajima, K.Hara, T.Kageji, Y.Mizobuchi, K.T.Kitazato, T.Fujihara, K.Kuwayama, R.Otsuka, D K.Kung, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Dkk-3, one of Dickkopf (Dkk) family members, contributes to the anti-tumor effects in glioblastoma through regulation of both Wnt signal pathways2013
- Author(s)
  K.Hara, T.Kageji, Y.Mizobuchi, K.T.Kitazato, T.Okazaki, T.Fujihara, K.Nakajima, H.Mure, K.Kuwayama, T.Hara, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Role of hyperhomocysteinemia in the development of intracranial aneurysms
- Author(s)
  Korai M, Kitazato KT, Miyamoto T, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  International Stroke Conference
- Place of Presentation
  Nashville、USA
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-24390344
[Presentation] Hemodynamic change elicits the formation and rupture of experimental cerebral aneurysms
- Author(s)
  Miyamoto T,, David K. Kung, Korai M, Kitazato KT, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  International Stroke Conference
- Place of Presentation
  Nashville、USA
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-24390344
[Presentation] Hemodynamic changes may elicit the formation and rupture of experimental cerebral aneurysms
- Author(s)
  Miyamoto T, David K. Kung, Korai M, Kitazato KT, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390344
[Presentation] Activation of M2 macrophage in the late phase after cerebral ischemia promotes the expression of neurogenesis related molecules
- Author(s)
  Kurashiki Y, Kitazato K1, Uto Y, Yagi K, Shimada K, Miyamoto T1, Sumiyoshi M, Tada Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390344
[Presentation] Is the regulation of M1 macrophage activation beneficial in the acute phase of post cerebral ischemia?
- Author(s)
  Kurashiki Y, Kitazato K, Uto Y, Yagi K, Shimada K, Miyamoto T, Sumiyoshi M, Tada Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  International Stroke Conference
- Place of Presentation
  Nashville、USA
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-24390344
[Presentation] Is the regulation of M1 macrophage activation beneficial in the acute phase of post cerebral ischemia?
- Author(s)
  Kurashiki Y, Kitazato K1, Uto Y, Yagi K, Shimada K, Miyamoto T1, Sumiyoshi M, Tada Y, Kuwayama K, Satomi J, Nagahiro S
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390344

1. NAGAHIRO Shinji (60145315)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. TADA Yoshiteru (30547964)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. SATOMI Junichiro (10304510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. 兼松康久 (90363142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. MORIGAKI Ryoma (70710565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MIZOBUCHI Yoshifumi (80547993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. MURE Hideo (00624355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. KAGEJI Teruyoshi (70294684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. NAKAJIMA Kohei (40710554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. HARA Keijirou (60710340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 八木謙次 (80551837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 高麗雅章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 島田健司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuwayama Kazuyuki 桑山 一行

KUWAYAMA Kauyuki 桑山 一行

Research Projects

Research Products

Co-Researchers

Early diagnosis and pharmacological treatment to prevent the rupture of cerebral aneurysms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of selective estrogen receptor modulators on cerebrovascular diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anti-tumor effects and Regulation of Wnt signaling pathway of adenovirus-mediated DKK3 in glioblastoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms underlying the rupture of cerebral aneurysms and the pharmacological regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Treatment Outcome of Carotid Artery Stenting Underwent within 14 Days of Stroke Onset – Consideration of Safety and Efficacy of Urgent Carotid Artery Stenting for Neurologically Progressing Patients2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Pulsatile Tinnitus due to an Aberrant Internal Carotid Artery in the Middle Ear:A Case Report2017

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PPARγ-Dependent and -Independent Inhibition of the HMGB1/TLR9 Pathway by Eicosapentaenoic Acid Attenuates Ischemic Brain Damage in Ovariectomized Rats2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of plasma biomarkers including angiotensin-(1-7) after switching from other angiotensin II type I receptor blockers to olmesartan in stroke patients with insufficient blood pressure control2015

Author(s)

Journal Title

Data Source

[Journal Article] Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The accumulation of brain water-free sodium is associated with ischemic damage independent of the blood pressure in female rats2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intra-arterial signal on arterial spin labeling perfusion MRI to identify the presence of acute middle cerebral artery occlusion2014

Kuwayama Kazuyuki 桑山一行

KUWAYAMA Kauyuki 桑山一行