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Okuno Alato  奥野 海良人

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OKUNO Alato  奥野 海良人

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Researcher Number 50623980
Other IDs
Affiliation (Current) 2025: 柴田学園大学, 生活創生学部, 准教授
Affiliation (based on the past Project Information) *help 2025: 柴田学園大学, 生活創生学部, 准教授
2021 – 2023: 柴田学園大学, 生活創生学部, 准教授
2018 – 2020: つくば国際大学, 医療保健学部, 講師(移行)
2017: 国立研究開発法人国立長寿医療研究センター, その他部局等, その他
2016: 国立研究開発法人国立長寿医療研究センター, ラジオアイソトープ管理室, 外来研究員 … More
2015: 国立研究開発法人国立長寿医療研究センター, ラジオアイソトープ管理室, 特任研究員
2015: 国立研究開発法人国立長寿医療研究センター, ラジオアイソトープ管理室, 研究員
2014: 独立行政法人国立長寿医療研究センター, 長寿医療研究センター・ラジオアイソトープ管理室, 特任研究員
2012 – 2014: 独立行政法人国立長寿医療研究センター, ラジオアイソトープ管理室, 特任研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 38050:Food sciences-related / 0601:Agricultural chemistry and related fields / Basic Section 08030:Family and consumer sciences, and culture and living-related / Eating habits
Except Principal Investigator
Pathological medical chemistry / Basic Section 52010:General internal medicine-related
Keywords
Principal Investigator
トリプトファン / キヌレニン / プロバイオティクス / 脳神経疾患 / プレバイオティクス / TDO / IDO / インドール-3-プロピオン酸 / インドール-3-酢酸 / 腸内環境 … More / トリプトファン代謝 / 腸脳相関 / 神経疾患 / 免疫 / 樹状細胞 / アミロイドβ / アルツハイマー病 / 栄養 / キノリン酸 / キヌレン酸 … More
Except Principal Investigator
アルツハイマー病 / Aig1l遺伝子 / 東洋医学 / 漢方 / 鍼灸 / 膜タンパク質 / Aig1l / 疾患エクソソーム / 代謝異常学 / 軽度認知症障害 / オミックス解析 / 脳リキッドバイオプシー / アストロサイト由来エクソソーム / 神経細胞由来エクソソーム / 多層的オミックス解析 / リキッドバイオプシー / エクソソーム / 認知症 / IDO / IDO / 神経毒 / キノリン酸 / アミロイドβペプチド / トリプトファン代謝 Less
  • Research Projects

    (8 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (8 People)
  •  うつ病の原因物質キヌレニンの調節に関わる肝臓と腎臓の役割Principal Investigator

    • Principal Investigator
      奥野 海良人
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Shibata Gakuen University
  •  精神疾患に関連する中枢トリプトファン代謝の末梢調節Principal Investigator

    • Principal Investigator
      奥野 海良人
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Shibata Gakuen University
  •  Suppression of brain inflammation through induction of endogenous anti-inflammatory compound by prebiotics and probioticsPrincipal Investigator

    • Principal Investigator
      Okuno Alato
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0601:Agricultural chemistry and related fields
    • Research Institution
      Shibata Gakuen University
  •  トリプトファン摂取による腸管IDO誘導機構の解明Principal Investigator

    • Principal Investigator
      奥野 海良人
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Tsukuba International University
  •  Relationship between the biological function and/or effect of acupuncture of Aig1l gene discovered by acupuncture stimulation

    • Principal Investigator
      Takaoka Yutaka
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kobe University
  •  Pathological analysis of Alzheimer`s disease through multi-layered omics study of blood exosomes derived from brain

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  The Alzheimer's disease prevention and treatment by nutritional increase in endogenous neuro-protective mediator, kynurenic acid in brainPrincipal Investigator

    • Principal Investigator
      OKUNO Alato
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Eating habits
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  The mechanisms of quinolinic acid-induced infiltration of reactive astrocytes and the amyloid beta peptide production in the activated glial cells

    • Principal Investigator
      TAKIKAWA Osamu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Geriatrics and Gerontology

All 2024 2023 2022 2018 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

  • [Journal Article] Probiotic lactic acid bacteria promote anti-tumor immunity through enhanced major histocompatibility complex class I-restricted antigen presentation machinery in dendritic cells2024

    • Author(s)
      Saito Suguru、Okuno Alato、Peng Zhenzi、Cao Duo-Yao、Tsuji Noriko M.
    • Journal Title

      Frontiers in Immunology

      Volume: 15

    • DOI

      10.3389/fimmu.2024.1335975

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K05543
  • [Journal Article] Creatine supplementation enhances immunological function of neutrophils by increasing cellular adenosine triphosphate2022

    • Author(s)
      SAITO Suguru、CAO Duo-Yao、OKUNO Alato、LI Xiaomo、PENG Zhenzi、KELEL Musin、TSUJI Noriko M
    • Journal Title

      Bioscience of Microbiota, Food and Health

      Volume: 41 Issue: 4 Pages: 185-194

    • DOI

      10.12938/bmfh.2022-018

    • ISSN
      2186-3342
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20573
  • [Journal Article] <i>Lactococcus lactis</i> subsp. <i>cremoris</i> C60 induces macrophages activation that enhances CD4+ T cell-based adaptive immunity2022

    • Author(s)
      SAITO Suguru、OKUNO Alato、KAKIZAKI Nanae、MAEKAWA Toshio、TSUJI Noriko M.
    • Journal Title

      Bioscience of Microbiota, Food and Health

      Volume: 41 Issue: 3 Pages: 130-136

    • DOI

      10.12938/bmfh.2021-057

    • ISSN
      2186-3342
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K20573
  • [Journal Article] Lymphocyte antigen 6 complex locus G6D downregulation is a novel parameter for functional impairment of neutrophils in aged mice2022

    • Author(s)
      Suguru Saito, Alato Okuno, Toshio Maekawa, Ryoki Kobayashi, Osamu Yamashita, Noriyuki Tsujimura, Morihiko Inaba, Yasushi Kageyama, Noriko M. Tsuji.
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 1001179-1001179

    • DOI

      10.3389/fimmu.2022.1001179

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09846, KAKENHI-PROJECT-22K05543
  • [Journal Article] Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice2022

    • Author(s)
      Yajima Yuhei、Okuno Alato、Nakamura Isamu、Miyazaki Teruo、Honda Akira、Toyoda Atsushi
    • Journal Title

      International Journal of Tryptophan Research

      Volume: 15 Pages: 1-9

    • DOI

      10.1177/11786469211066285

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11219, KAKENHI-PROJECT-21K20573
  • [Journal Article] Dietary Hesperidin Suppresses Lipopolysaccharide-Induced Inflammation in Male Mice2022

    • Author(s)
      Sato Mizuho、Okuno Alato、Ishisono Keita、Yajima Yuhei、Toyoda Atsushi
    • Journal Title

      International Journal of Tryptophan Research

      Volume: 15

    • DOI

      10.1177/11786469221128697

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K05543, KAKENHI-PROJECT-21K17587, KAKENHI-PROJECT-21K20573
  • [Journal Article] Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B.2016

    • Author(s)
      Yoshio S, Sugiyama M, Shoji H, Mano Y, Mita E, Okamoto T, Matsuura Y, Okuno A, Takikawa O, Mizokami M, Kanto T.
    • Journal Title

      Hepatology

      Volume: 63 Issue: 1 Pages: 83-94

    • DOI

      10.1002/hep.28282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08326, KAKENHI-PROJECT-25860574
  • [Journal Article] New Inhibitors of Indoleamine 2,3-Dioxygenase 1: Molecular Modeling Studies, Synthesis, and Biological Evaluation.2016

    • Author(s)
      Coluccia A, Passacantilli S, Famiglini V, Sabatino M, Patsilinakos A, Ragno R, Mazzoccoli C, Sisinni L, Okuno A, Takikawa O, Silvestri R, La Regina G.
    • Journal Title

      J Med Chem.

      Volume: 59 Pages: 9760-9773

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Journal Article] Affinity imaging mass spectrometry (AIMS): high-throughput screening for specific small molecule interactions with frozen tissue sections.2015

    • Author(s)
      Yoshimi T, Kawabata S, Taira S, Okuno A, Mikawa R, Murayama S, Tanaka K, Takikawa O.
    • Journal Title

      Analyst

      Volume: 140 Issue: 21 Pages: 7202-7208

    • DOI

      10.1039/c5an01381j

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Journal Article] Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection.2013

    • Author(s)
      Higashitani K, Kanto T, Kuroda S, Yoshio S, Matsubara T, Kakita N, Oze T, Miyazaki M, Sakakibara M, Hiramatsu N, Mita E, Imai Y, Kasahara A, Okuno A, Takikawa O, Hayashi N, Takehara T.
    • Journal Title

      J Gastroenterol.[Epub ahead of print]

      Volume: 未定

    • NAID

      10031177017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Journal Article] NMR-based metabolomics of urine in a mouse model of Alzheimer’s disease: identification of oxidative stress biomarkers2013

    • Author(s)
      Fukuhara, K., Ohno, A., Ota, Y., Senoo, Y., Maekawa, K., Okuda, H., Kurihara, M., Okuno, A., Niida, S., Saito, Y., Takikawa, O
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 52 Issue: 2 Pages: 133-138

    • DOI

      10.3164/jcbn.12-118

    • NAID

      130004466706

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390038, KAKENHI-PROJECT-22790126, KAKENHI-PROJECT-24590397
  • [Journal Article] Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer's disease.2013

    • Author(s)
      Tajima Y, Ishikawa M, Maekawa K, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Ikeda K, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y.
    • Journal Title

      Lipids Health Dis

      Volume: 12 Issue: 1 Pages: 68-68

    • DOI

      10.1186/1476-511x-12-68

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-24390067, KAKENHI-PROJECT-24590397, KAKENHI-PROJECT-24619007, KAKENHI-PUBLICLY-25116702, KAKENHI-PROJECT-25750068
  • [Patent] 化学・物理現象検出方法及びその装置2014

    • Inventor(s)
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Holder
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-05-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Patent] 化学・物理現象検出方法及びその装置2013

    • Inventor(s)
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Holder
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-112444
    • Filing Date
      2013-05-29
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Patent] 化学・物理現象検出方法及びその装置2013

    • Inventor(s)
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Holder
      滝川修、奥野海良人、吉見立也、澤田和明、奥村弘一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-05-29
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Patent] アルツハイマー病の発症を予測する方法2012

    • Inventor(s)
      滝川修・奥野海良人・その他5名
    • Industrial Property Rights Holder
      滝川修・奥野海良人・その他5名
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-151620
    • Filing Date
      2012-07-05
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] 乳酸菌X株の死菌体投与がトリプトファン-キヌレニン代謝に及ぼす影響2023

    • Author(s)
      一戸唯華、前多隼人、織田夏美、奥野海良人
    • Organizer
      日本トリプトファン研究会
    • Data Source
      KAKENHI-PROJECT-22K05543
  • [Presentation] GAN誘導性NASHモデルマウスでは膵臓のキヌレニン代謝関連遺伝子が軒並み増加する2022

    • Author(s)
      橘髙 充加、髙橋 万由花、土屋 友梨華、奥野 海良人、安原 香子、小林 謙一
    • Organizer
      日本トリプトファン研究会
    • Data Source
      KAKENHI-PROJECT-22K05543
  • [Presentation] Kynurenine metabolism is involved in the link between nonalcoholic fatty liver disease (NASH) and chronic kidney disease (CKD)2022

    • Author(s)
      Mayuka Takahashi, Misaki Suzuki, Maiko Takasuga, Mika Kittaka, Mamiko Ishikawa, Junko Ohki, Alato Okuno, Yoshiko Mori, Ken-Ichi Kobayashi
    • Organizer
      IUNS-ICN 22nd International Congress of Nutrition in Tokyo, Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K05543
  • [Presentation] 飼料の摂取がトリプトファン‐キヌレニン代謝に及ぼす影響2022

    • Author(s)
      木村仁実、織田夏海、佐藤梨沙、奥野 海良人
    • Organizer
      日本トリプトファン研究会
    • Data Source
      KAKENHI-PROJECT-22K05543
  • [Presentation] 幼若期のマウスを用いた社会的敗北モデルの作成と評価2018

    • Author(s)
      大澤夏樹、奥野海良人、豊田淳
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K02211
  • [Presentation] ヘスペリジンの給与は慢性社会的敗北ストレスによる脳内キヌレニンの増加を抑制し、社会的ストレスに対する抵抗性(レジリエンス)を付与する2018

    • Author(s)
      佐藤瑞穂、奥野海良人、鈴木一徳、大澤夏樹、井上栄一、宮口右二、豊田 淳
    • Organizer
      第24回 Hindgut Club Japanシンポジウム
    • Data Source
      KAKENHI-PROJECT-18K02211
  • [Presentation] Dietary intake of hesperidin suppresses brain kynurenine levels and social avoidance behavior in the depression model of mouse2018

    • Author(s)
      Mizuho Sato, Alato Okuno, Kazunori Suzuki, Natsuki Ohsawa, Eiichi Inoue, Yuji Miyaguchi , Atsushi Toyoda
    • Organizer
      The 15th Meeting of International Society for Tryptophan Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K02211
  • [Presentation] 切皮刺激による皮下組織への治療効果の検討(第一報)2018

    • Author(s)
      奥野海良人、大田美香、高岡 裕
    • Organizer
      第67回全日本鍼灸学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K07414
  • [Presentation] ヘスペリジンの慢性給与は心理社会的ストレスに対する抵抗性を向上させる2018

    • Author(s)
      佐藤瑞穂、鈴木一徳、大澤夏樹、奥野海良人、井上栄一、宮口右二、豊田淳
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K02211
  • [Presentation] Relationship between non-B, non-C hepatocellular carcinoma and tryptophan-kynurenine metabolism2018

    • Author(s)
      Okuno A, Kamiya S, Watanabe Y, Kobayashi K, Yamamoto Y, Tsuji MN
    • Organizer
      The 15th Meeting of International Society for Tryptophan Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K02211
  • [Presentation] ヒト血清中のアミロイドβ分解活性の性状解析2015

    • Author(s)
      三河隆太、奥野海良人、吉見立也、滝川修
    • Organizer
      第38回日本基礎老化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-14
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] Development of High-speed and Super Sensitive Device for Detection of Amyloid-β Peptide Using an Ion Image Sensor.2015

    • Author(s)
      Okuno A, Yoshimi T, Okumura K, Sawada K, Takikawa O.
    • Organizer
      26th IEEE International Symposium on Micro-NanoMehatronics and Human Science in 2015
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2015-11-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] マウスにおけるトリプトファン摂取が神経保護物質キヌレン酸および神経毒キノリン酸の脳内および血液レベルに及ぼす影響2015

    • Author(s)
      奥野 海良人,三河 隆太,吉見 立也,滝川 修
    • Organizer
      日本アミノ酸学会 第9回学術大会(JSAAS2015)
    • Place of Presentation
      滋賀県彦根市
    • Year and Date
      2015-10-23
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] Trp supplementation decreases KYNA/QA ratio in the mouse brain.2015

    • Author(s)
      Okuno A, Yoshimi T, Mikawa R and Takikawa O.
    • Organizer
      The 14th Meeting of International Society for Tryptophan Research
    • Place of Presentation
      アメリカ(ミシガン)
    • Year and Date
      2015-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] Trp supplementation decreases KYNA/QA ratio in the mouse brain.2015

    • Author(s)
      Okuno A, Yoshimi T, Mikawa R, Takikawa O.
    • Organizer
      2015 ISTRY Conference
    • Place of Presentation
      Grand Rapids, USA.
    • Year and Date
      2015-11-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] マウスにおけるトリプトファン摂取が神経保護物質キヌレン酸および神経毒キノリン酸の脳内および血液レベルに及ぼす影響2015

    • Author(s)
      奥野海良人、三河隆太、吉見立也、滝川修
    • Organizer
      日本アミノ酸学会第9回学術大会(JSAAS2011)
    • Place of Presentation
      彦根
    • Year and Date
      2015-10-24
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] AIMS: 親和性化合物イメージング質量分析スクリーニングシステム2015

    • Author(s)
      吉見立也、川畑慎一郎、奥野海良人、三河隆太、田中耕一、滝川修
    • Organizer
      BMB2015(分子生物学会、生化学会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] マイクロバイオ化学センサによる健康管理2015

    • Author(s)
      澤田和明、奥野海良人、滝川修、奥村弘一、服部敏明
    • Organizer
      日本機械学会第7回マイクロ・ナノ工学シンポジウム
    • Place of Presentation
      新潟
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-15K08326
  • [Presentation] Characterization of Amyloid-β Degrading Activity in Human Serum.2014

    • Author(s)
      Mikawa R, Okuno A, Takayanagi A, Okada K, Yoshimi T, Takikawa O.
    • Organizer
      日本基礎老化学会第37回大会
    • Place of Presentation
      東浦
    • Year and Date
      2014-06-26
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] イオンイメージセンサを用いたアルツハイマー病原因物質の高速高感度測定装置の開発2014

    • Author(s)
      奥野海良人
    • Organizer
      中部地区 医療・バイオ系シーズ発表会 新技術説明会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2014-12-10
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] New modulator of the tumoural immuno escape via Indoleamin 2,3-dioxygenase (IDO) inhibition.2014

    • Author(s)
      Antonio Coluccia, Giuseppe La Regina, Okuno A, Takikawa O, Romano Silvestri.
    • Organizer
      XXV CONGRESSO NAZIONALE DELLA SCI “SCI2014”
    • Place of Presentation
      Rend CS, Italy.
    • Year and Date
      2014-09-07
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] ヒト血清中のアミロイドβ分解活性の同定2014

    • Author(s)
      三河隆太、奥野海良人、高柳亜紀子、吉見立也、滝川修
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Kinetic and protein-ligand interaction studies of human tryptophan 2,3-dioxygenase, identified the modulation of enzymatic reactions by tryptophan.2013

    • Author(s)
      岡田健、三河隆太、奥野海良人、高柳亜紀子、山岸まゆみ、吉見立也、滝川修
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] ヒトTryptophan 2,3-dioxygenaseのアロステリック効果による酵素反応調節機構2013

    • Author(s)
      岡田健、三河隆太、奥野海良人、吉見立也、滝川修
    • Organizer
      第35回日本トリプトファン研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] 経管栄養施行中の重症心身障害児(者)の栄養障害と免疫機能 -インドールアミン酸素添加酵素(IDO)との関連について-2013

    • Author(s)
      大森啓充、滝川修、眞山義民、奥野海良人、山﨑雅美、福場浩正、村田芳夫、松本信夫、品川友江、宮地隆史、住元了、鈴木修一、 宮野前健、児玉浩子
    • Organizer
      第35回日本臨床栄養学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Implications of brain microvessel endothelial cell-derived amyloid β peptide in cerebral amyloid angiopathy associated with Alzheimer’s disease.2013

    • Author(s)
      Takikawa O, Mikawa R, Okuno A, Yoshimi T, Okada K, Takayanagi A.
    • Organizer
      Alzheimer’s disease Association International Conference (AAIC) 2013
    • Place of Presentation
      Boston, America
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] 経管栄養施行中の重症心身障害児(者)の栄養障害と免疫機能 – インドールアミン酸素添加酵素(IDO)との関連について–2013

    • Author(s)
      大森啓充、滝川修、眞山義民、奥野海良人、山﨑雅美、福場浩正、村田芳夫、松本信夫、品川友江、宮地隆史、住元了、鈴木修一、 宮野前健、児玉浩子
    • Organizer
      第35回日本臨床栄養学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] 血管内皮細胞によるAβ産生調節機構:脳アミロイド血管症におけるその病態生理学的意義2013

    • Author(s)
      三河隆太、吉見立也、奥野海良人、岡田健、高柳亜紀子、滝川修
    • Organizer
      第86回日本生化学会大会、2013年9月11日、
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] 血管内皮細胞におけるAβ産生機構と脳アミロイド血管症2013

    • Author(s)
      三河隆太、吉見立也、奥野海良人、岡田健、高柳亜紀子、滝川修
    • Organizer
      第36回日本基礎老化学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] 脳血管細胞によるAβ産生と脳アミロイド血管症2013

    • Author(s)
      三河隆太、奥野海良人、岡田健、高柳亜紀子、吉見立也、滝川修
    • Organizer
      第35回神経組織培養研究会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease.2013

    • Author(s)
      Tajima Y, Maekawa Keiko, Ishikawa M, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Kazutaka I, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y.
    • Organizer
      The 9th Annual Conference of the Metabolomics Society
    • Place of Presentation
      Glasgow, Scotland
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] NMRを用いたアルツハイマー病モデルマウスのメタボローム解析2012

    • Author(s)
      福原 潔、大野彰子、太田庸介、前川京子、奥田晴宏、栗原正明、奥野海良人、新飯田俊平、斎藤嘉朗、滝川 修
    • Organizer
      第65回日本酸化ストレス学会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] 脳血管細胞によるAβ産生と脳アミロイド血管症

    • Author(s)
      三河隆太、奥野海良人、岡田健、高柳亜紀子、吉見立也、滝川修
    • Organizer
      第35回神経組織培養研究会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] 反応性アストロサイトによるアミロイドβペプチド産生機構

    • Author(s)
      吉見立也、奥野海良人、岡田健、三河隆太、高柳亜紀子、滝川修
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Development of High-speed and Super Sensitive Device for Detection of Amyloid-β Peptide Using an Ion Image Sensor.

    • Author(s)
      Okuno A, Yoshimi T, Okumura K, Sawada K, Takikawa O.
    • Organizer
      IEEE International Symposium on Micro-NanoMechatronics and Human Science(MHS) 2014
    • Place of Presentation
      Nagoya,Japan.
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Kinetic and protein-ligand interaction studies of human tryptophan 2,3-dioxygenase, identified the modulation of enzymatic reactions by tryptophan.

    • Author(s)
      岡田健、三河隆太、奥野海良人、高柳亜紀子、山岸まゆみ、吉見立也、滝川修
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Characterization of Amyloid-βDegrading Activity in Human Serum.

    • Author(s)
      三河隆太、吉見立也、奥野海良人、岡田健、高柳亜紀子、滝川修
    • Organizer
      第6回NAGOYAグローバルリトリート
    • Place of Presentation
      東浦
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] 血管内皮細胞におけるAβ産生機構と脳アミロイド血管症

    • Author(s)
      三河隆太、吉見立也、奥野海良人、岡田健、高柳亜紀子、滝川修
    • Organizer
      第36回日本基礎老化学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Lipidomic analysis of brain and plasma from a mouse model of Alzheimer’s disease.

    • Author(s)
      Tajima Y, Maekawa K, Ishikawa M, Murayama M, Nishimaki-Mogami T, Nakanishi1 H, Ikeda K, Arita M, Taguchi R, Gong J, Okuno A, Niida S, Takikawa O, Saito Y.
    • Organizer
      第53回国際脂質生化学会
    • Place of Presentation
      Banff, Canada
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Characterization of Amyloid-β Degrading Activity in Human Serum.

    • Author(s)
      Mikawa R, Okuno A, Takayanagi A, Okada K, Yoshimi T, Takikawa O.
    • Organizer
      日本基礎老化学会第37回大会
    • Place of Presentation
      愛知県知多郡
    • Year and Date
      2014-06-26 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] Implications of brain microvessel endothelial cell-derived amyloid β peptide in cerebral amyloid angiopathy associated with Alzheimer’s disease.

    • Author(s)
      Takikawa O, Mikawa R, Okuno A, Yoshimi T, Okada K, Takayanagi A.
    • Organizer
      Alzheimer’s disease Association International Conference (AAIC) 2013
    • Place of Presentation
      Boston, America.
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] 血管内皮細胞によるAβ産生調節機構:脳アミロイド血管症におけるその病態生理学的意義

    • Author(s)
      三河隆太、吉見立也、奥野海良人、岡田健、高柳亜紀子、滝川修
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] ヒトTryptophan 2,3-dioxygenaseのアロステリック効果による酵素反応調節機構

    • Author(s)
      岡田健、三河隆太、奥野海良人、吉見立也、滝川修
    • Organizer
      第35回日本トリプトファン研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease.

    • Author(s)
      Tajima Y, Maekawa Keiko, Ishikawa M, Murayama M, Senoo Y, Nishimaki-Mogami T, Nakanishi H, Kazutaka I, Arita M, Taguchi R, Okuno A, Mikawa R, Niida S, Takikawa O, Saito Y.
    • Organizer
      The 9th Annual Conference of the Metabolomics Society
    • Place of Presentation
      Glasgow, Scotland
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Aβ Production from Reactive Astrocytes Induced by Endogenous Neurotoxin Quinolinic Acid : A New Aspect of Alzheimer’s Disease.

    • Author(s)
      Okuno A, Zhang G, Yoshimi T, Mikawa R, Takikawa O.
    • Organizer
      Alzheimer’s disease Association International Conference (AAIC) 2012
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Pathogenic role of IDO in Alzheimer’s disease: Astrocytes but not neurons are responsible for the increase of amyloid β peptide induced by neurotoxin quinolinic acid.

    • Author(s)
      Okuno A, Yoshimi T, Okada K, Mikawa R, Takayanagi A, Takikawa O.
    • Organizer
      第13回国際トリプトファン研究会
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24590397
  • [Presentation] Development of High-speed and Super Sensitive Device for Detection of Amyloid-β Peptide Using an Ion Image Sensor.

    • Author(s)
      Okuno A, Yoshimi T, Okumura K, Sawada K, Takikawa O.
    • Organizer
      IEEE International Symposium on Micro-NanoMechatronics and Human Science(MHS) 2014
    • Place of Presentation
      Nagoya, Aichi, Japan
    • Year and Date
      2014-11-23 – 2014-11-25
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] New modulator of the tumoural immuno escape via Indoleamin 2,3-dioxygenase (IDO) inhibition.

    • Author(s)
      Antonio Coluccia, Giuseppe La Regina, Okuno A, Takikawa O, Romano Silvestri.
    • Organizer
      XXV CONGRESSO NAZIONALE DELLA SCI “SCI2014”
    • Place of Presentation
      Rend CS, Italy
    • Year and Date
      2014-09-07 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-25750068
  • [Presentation] アルツハイマー病モデルマウスの脳組織及び血漿における脂質メタボローム解析

    • Author(s)
      田島陽子、前川京子、石川将己、村山真由子、妹尾勇弥、最上(西巻)知子、中西広樹、池田和貴、有田誠、田口良、檜垣小百合、奥野海良人、新飯田俊平、滝川修、斎藤嘉朗
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590397
  • 1.  TAKIKAWA Osamu (70163342)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 2.  Takaoka Yutaka (20332281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  大田 美香 (20274706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  菅野 亜紀 (20457039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  鈴木 高史 (70305530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KOBAYASHI Ryoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  中村 勇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  有田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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