Yamazaki Tatsuya 山崎達也

Researcher Number	50624087
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 愛知医科大学, 医学部, 講師 2019: 愛知医科大学, 医学部, 助教 2014 – 2015: 東京大学, 医科学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Virology Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator インフルエンザウイルス / RP105 / ワクチン / アジュバント / 遺伝子免疫 / 抗体遺伝子 / トル様受容体 / 架橋 / エピトープ / アゴニスト抗体 … More / インフルエンザ / ヘマグルチニン / 自然免疫 / 感染症 / 遺伝子ワクチン / DNA免疫 / 糖鎖 / B細胞 / TLR / 自然免疫受容体 / RP105(CD180) / CD4T細胞 / ヒトリンパ球 / HA / 抗原 / 並体結合マウス / IgA … More Except Principal Investigator 抗原特異的抗体 / 自然免疫受容体 / ヒトB細胞 Less

Development of an innovative method to generate antigen-specific antibody-producing B-cells from human naive B cells in vitro
- Principal Investigator
  
  岩崎研太
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Aichi Medical University
トル様受容体RP105特異抗体を基盤とした遺伝子ワクチンアジュバントの開発Principal Investigator
- Principal Investigator
  
  山崎達也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Aichi Medical University
Development of a vaccine adjuvant with an agonistic monoclonal antibody against Toll-like receptorPrincipal Investigator
- Principal Investigator
  
  Yamazaki Tatsuya
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Aichi Medical University
The mechanism of virus-specific IgA induction in nasal mucosaPrincipal Investigator
- Principal Investigator
  
  Yamazaki Tatsuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Antibody gene transfer for passive-immunization and vaccine adjuvant against influenza virus2024
- Author(s)
  山崎達也、髙村(赤司) 祥子
- Journal Title
  
  Endotoxin and Innate Immunity
  
  Volume: 24 Issue: 0 Pages: 1-8
- DOI
  10.24753/jeiis.24.0_1
- ISSN
  2434-1177
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07491
[Journal Article] Cell surface expression of human<scp>RP105</scp>depends on<i>N</i>‐glycosylation of<scp>MD</scp>‐12022
- Author(s)
  Biswas Mrityunjoy、Yamazaki Tatsuya、Tomono Susumu、Karnan Sivasundaram、Takagi Hidekazu、Ichimonji Isao、Inui Masanori、Nagaoka Fumiaki、Hosokawa Yoshitaka、Akashi‐Takamura Sachiko
- Journal Title
  
  FEBS Letters
  
  Volume: 596 Issue: 24 Pages: 3211-3231
- DOI
  10.1002/1873-3468.14452
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07491, KAKENHI-PROJECT-22K08294, KAKENHI-PROJECT-22K08611, KAKENHI-PROJECT-17K08874, KAKENHI-PROJECT-19K08500, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-20K11635, KAKENHI-PROJECT-22K08985
[Journal Article] A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza2020
- Author(s)
  Yamazaki Tatsuya、Biswas Mrityunjoy、Kosugi Kouyu、Nagashima Maria、Inui Masanori、Tomono Susumu、Takagi Hidekazu、Ichimonji Isao、Nagaoka Fumiaki、Ainai Akira、Hasegawa Hideki、Chiba Joe、Akashi-Takamura Sachiko
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 606518-606518
- DOI
  10.3389/fimmu.2020.606518
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08874, KAKENHI-PROJECT-19K07491, KAKENHI-PROJECT-19K08500, KAKENHI-PROJECT-20K11635
[Journal Article] Broadly Neutralizing Antibodies for Influenza: Passive Immunotherapy and Intranasal Vaccination2020
- Author(s)
  Biswas Mrityunjoy、Yamazaki Tatsuya、Chiba Joe、Akashi-Takamura Sachiko
- Journal Title
  
  Vaccines
  
  Volume: 8 Issue: 3 Pages: 424-424
- DOI
  10.3390/vaccines8030424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07491, KAKENHI-PROJECT-19K08500
[Journal Article] Could a sugar chain on IgE be a new target for therapy for allergy?2019
- Author(s)
  Tatsuya Yamazaki, Sachiko Akashi-Takamura
- Journal Title
  
  Glycoforum
  
  Volume: 22 Issue: 5 Pages: A15
- DOI
  10.32285/glycoforum.22A15
- ISSN
  1349-9416
- Year and Date
  2019-12-02
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07491, KAKENHI-PROJECT-19K08500
[Journal Article] Receptor-destroying enzyme (RDE) from <i>Vibrio cholerae</i> inactivates the function of IgE and reduces anaphylaxis2019
- Author(s)
  山崎達也、高村 (赤司) 祥子
- Journal Title
  
  Endotoxin and Innate Immunity
  
  Volume: 22 Issue: 0 Pages: 72-78
- DOI
  10.24753/jeiis.22.0_72
- NAID
  130007742297
- ISSN
  2434-1177
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] TLRファミリー分子RP105に対するアゴニスト抗体はインフルエンザウイルス感染予防のための遺伝子免疫でアジュバント効果を示す2023
- Author(s)
  山崎達也,高村祥子
- Organizer
  ２０２２年度東海乳酸菌研究会総会・研究発表会
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] 自然免疫受容体RP105に対するアゴニスト抗体を用いたB細胞活性化とその応用2022
- Author(s)
  山崎達也
- Organizer
  第10回Transplant Immunology Forum
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] Recombinant anti-RP105 provides an adjuvant effect for gene immunization against influenza2022
- Author(s)
  Tatsuya Yamazaki,Mrityunjoy Biswas,Masanori Inui,Susumu Tomono,Sachiko Akashi-Takamura
- Organizer
  The 51th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] ヒトRP105の細胞膜上への発現はMD-1に付加したN結合型糖鎖に依存する2022
- Author(s)
  山崎達也,高村(赤司)祥子
- Organizer
  第27回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] Agonistic anti-radioprotective 105 shows adjuvant effect for DNA immunization against influenza2021
- Author(s)
  山崎達也, Mrityunjoy Biswas, 乾匡範, 伴野勧, 一文字功, 相内章, 高村(赤司)祥子
- Organizer
  第50回免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] 「抗体遺伝子を用いた感染症防御への挑戦」2021
- Author(s)
  山崎達也
- Organizer
  第26回日本エンドトキシン・自然免疫研究会奨励賞(最優秀賞)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] The effect of commercial receptor-destroying enzyme (RDE) from Vibrio cholerae to human IgE activity2019
- Author(s)
  Tatsuya Yamazaki, Susumu Tomono, Masanori Inui, Isao Ichimonji, and Sachiko Akashi-Takamura
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07491
[Presentation] インフルエンザウイルス特異的IgA応答における上気道常在菌の役割2016
- Author(s)
  山崎達也
- Organizer
  5th Negative Strand Virus-Japan
- Place of Presentation
  ホテルモントレ沖縄（沖縄県国頭郡恩納村）
- Year and Date
  2016-01-25
- Data Source
  KAKENHI-PROJECT-26870127
[Presentation] 並体結合マウスを用いたインフルエンザウイルス特異的IgA抗体応答の解析2015
- Author(s)
  山崎達也
- Organizer
  第29回インフルエンザ研究者交流会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26870127
[Presentation] 並体結合マウスを用いたインフルエンザウイルス特異的IgA抗体応答の解析2014
- Author(s)
  山崎達也、一戸猛志
- Organizer
  第14回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学　伊藤国際学術研究センター
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26870127
[Presentation] ミトコンドリア品質管理タンパク質PINK1/ParkinによるNLRP3 inflammasomeの制御機構
- Author(s)
  山崎達也、小柴琢己、一戸猛志
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26870127
[Presentation] 並体結合マウスを用いたインフルエンザウイルス特異的IgA抗体応答の解析
- Author(s)
  山崎達也
- Organizer
  4th Negative Strand Virus-Japan
- Place of Presentation
  ラグナガーデンホテル　沖縄
- Year and Date
  2015-01-19 – 2015-01-21
- Data Source
  KAKENHI-PROJECT-26870127

1. 岩崎研太 (10508881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 高村祥子 (00325599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小林孝彰 (70314010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. INUI Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Tatsuya 山崎 達也

Research Projects

Research Products

Co-Researchers

Development of an innovative method to generate antigen-specific antibody-producing B-cells from human naive B cells in vitro

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

トル様受容体RP105特異抗体を基盤とした遺伝子ワクチンアジュバントの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a vaccine adjuvant with an agonistic monoclonal antibody against Toll-like receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of virus-specific IgA induction in nasal mucosaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Antibody gene transfer for passive-immunization and vaccine adjuvant against influenza virus2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Cell surface expression of human<scp>RP105</scp>depends on<i>N</i>‐glycosylation of<scp>MD</scp>‐12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Broadly Neutralizing Antibodies for Influenza: Passive Immunotherapy and Intranasal Vaccination2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Could a sugar chain on IgE be a new target for therapy for allergy?2019

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Receptor-destroying enzyme (RDE) from <i>Vibrio cholerae</i> inactivates the function of IgE and reduces anaphylaxis2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] TLRファミリー分子RP105に対するアゴニスト抗体はインフルエンザウイルス感染予防のための遺伝子免疫でアジュバント効果を示す2023

Author(s)

Organizer

Data Source

[Presentation] 自然免疫受容体RP105に対するアゴニスト抗体を用いたB細胞活性化とその応用2022

Author(s)

Organizer

Data Source

[Presentation] Recombinant anti-RP105 provides an adjuvant effect for gene immunization against influenza2022

Author(s)

Organizer

Data Source

[Presentation] ヒトRP105の細胞膜上への発現はMD-1に付加したN結合型糖鎖に依存する2022

Author(s)

Yamazaki Tatsuya 山崎達也

[Presentation] インフルエンザウイルス特異的IgA応答における上気道常在菌の役割2016

[Presentation] 並体結合マウスを用いたインフルエンザウイルス特異的IgA抗体応答の解析2015

[Presentation] 並体結合マウスを用いたインフルエンザウイルス特異的IgA抗体応答の解析