FUJIWARA Hiroaki 藤原弘明

Researcher Number	50634200
Affiliation (based on the past Project Information) *help	2016: 九州大学, 歯学研究院, 助教 2015: 九州大学, 大学院歯学研究院, 助教 2013 – 2015: 九州大学, 歯学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Morphological basic dentistry Except Principal Investigator Morphological basic dentistry
Keywords	Principal Investigator シグナル伝達経路 / 歯胚再生 / Runx2 / Thymosin beta 4 / シグナル伝達 / 歯の再生 Except Principal Investigator アポトーシス / 扁平上皮癌 / DCC / neural crest … More / tooth development / neural crest cell / set-alpha / FRG1 / I2PP2A / 象牙質形成 / エナメル質形成 / 歯の発生 Less

Thymosinシグナル伝達機構を利用したヒト歯胚の作製法の確立Principal Investigator
- Principal Investigator
  
  藤原弘明
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Novel anticancer therapy targeting specific genes for squamous cell carcinoma
- Principal Investigator
  
  Wada Hiroko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
A study of cellular signaling of PP2A inhibitor during the tooth development
- Principal Investigator
  
  Nagata Kengo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
変異型DCC遺伝子を利用した口腔癌細胞のアポトーシス誘導
- Principal Investigator
  
  坂井英隆
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Generation of the odontogenic epithelial cell by Thymosin beta 4 gene introductionPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hiroaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University

All 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Thymosin beta 4 is associated with RUNX2 expression via the Smad and Akt signaling pathways in mouse dental epithelial cells2015
- Author(s)
  Someya H., Fujiwara H.†, Nagata K., Wada H., Hasegawa K., Mikami Y., Jinno A., Sakai H., Koyano K. and Kiyoshima T. (†: Corresponding author)
- Journal Title
  
  Int. J. Mol. Med.
  
  Volume: 35 Issue: 5 Pages: 1169-1178
- DOI
  10.3892/ijmm.2015.2118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861747, KAKENHI-PROJECT-26462788, KAKENHI-PROJECT-25463124
[Journal Article] Itm2a expression in the developing mouse first lower molar, and the subcellular localization of itm2a in mouse dental epithelial cells.2014
- Author(s)
  Kihara M., Kiyoshima T., Nagata K., Wada H., Fujiwara H., Hasegawa K., Someya H., Takahashi I. and Sakai H.
- Journal Title
  
  PLoS One
  
  Volume: 9 (7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462788
[Journal Article] Induction of dental epithelial cell differentiation marker gene expression in non-odontogenic human keratinocytes by transfection with thymosin beta 4.2013
- Author(s)
  Kiyoshima T, Fujiwara H, Nagata K, Wada H, Ookuma YF, Shiotsuka M, Kihara M, Hasegawa K, Someya H, Sakai H
- Journal Title
  
  Stem Cell Res
  
  Volume: 12 Pages: 309-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861747
[Journal Article] Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression.2013
- Author(s)
  Kiyoshima T, Yoshida H, Wada H, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H, Sakai H.
- Journal Title
  
  PLoS One
  
  Volume: 8(11) Issue: 11 Pages: e80998-e80998
- DOI
  10.1371/journal.pone.0080998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463124, KAKENHI-PROJECT-25670779
[Presentation] 硬組織形成期歯胚におけるGlucose regulated protein-78タンパクの発現局在について2015
- Author(s)
  永田健吾、和田裕子、藤原弘明、三上友理恵、神野彰子、安倍みさき、清島　保
- Organizer
  第５７回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26462788
[Presentation] Immunoexpression of glucose regulated protein-78 in the mouse molar and incisor teeth during tooth development2015
- Author(s)
  永田健吾、藤原弘明、和田裕子、清島保
- Organizer
  第57回歯科基礎医学会学術大会・総会
- Place of Presentation
  朱鷺メッセ（新潟）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K20362
[Presentation] V-ATPase 阻害剤 Concanamycin A 抵抗性口腔扁平上皮癌細胞株に対する SAHA 併用による細胞増殖抑制効果2014
- Author(s)
  清島保, 永田健吾, 和田裕子, 藤原弘明, 坂井英隆
- Organizer
  第103回日本病理学会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25670779
[Presentation] 非歯原性上皮細胞へのThymosin beta 4 遺伝子導入による歯原性上皮細胞への誘導2014
- Author(s)
  藤原弘明、清島保、永田健吾、和田裕子、坂井英隆
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  ANAクラウンプラザホテル広島（広島）
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-25861747
[Presentation] 扁平上皮癌移植モデルマウスを用いたNetrin-1結合部位欠失DCC遺伝子導入の影響2013
- Author(s)
  和田裕子, 清島保, 藤原弘明, 坂井英隆
- Organizer
  第２４回日本臨床口腔病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25670779
[Presentation] 非歯原性上皮細胞へのThymosin beta 4 遺伝子導入による歯原性上皮細胞への誘導.
- Author(s)
  藤原弘明、清島保、永田健吾、和田裕子、坂井英隆
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  ANAクラウンプラザホテル広島（広島）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26462788
[Presentation] 歯胚の発生・発育におけるFacioscapulohumeral Muscular Dystrophy Region Gene 1（FRG1）の発現様式.
- Author(s)
  長谷川佳那、和田裕子、永田健吾、藤原弘明、染矢祐孝、神野彰子、三上友理恵、赤峰昭文、清島保
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462788
[Presentation] V-ATPase 阻害剤 Concanamycin A 抵抗性口腔扁平上皮癌細胞株に対する SAHA 併用による細胞増殖抑制効果.
- Author(s)
  清島保、永田健吾、和田裕子、藤原弘明、坂井英隆
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  ANAクラウンプラザホテル広島（広島）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26462788
[Presentation] マウス歯肉上皮由来角化細胞へのThymosin beta 4遺伝子導入による歯原性上皮細胞誘導
- Author(s)
  染矢祐孝、清島保、永田健吾、和田裕子、藤原弘明、木原槇子、長谷川佳那、古谷野潔、坂井英隆
- Organizer
  第55回歯科基礎医学会学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Data Source
  KAKENHI-PROJECT-25861747
[Presentation] Thymosin beta 4遺伝子導入による歯原性上皮細胞の作製
- Author(s)
  藤原弘明、清島保、永田健吾、和田裕子、木原槇子、長谷川佳那、染矢祐孝、坂井英隆
- Organizer
  第55回歯科基礎医学会学術大会・総会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Data Source
  KAKENHI-PROJECT-25861747

1. Nagata Kengo (90189134)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. KIYOSHIMA Tamotsu (20264054)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. WADA Hiroko (70380706)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. SAKAI Hidetaka (80136499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 藤井慎介 (60452786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJIWARA Hiroaki 藤原 弘明

Research Projects

Research Products

Co-Researchers

Thymosinシグナル伝達機構を利用したヒト歯胚の作製法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel anticancer therapy targeting specific genes for squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of cellular signaling of PP2A inhibitor during the tooth development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

変異型DCC遺伝子を利用した口腔癌細胞のアポトーシス誘導

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of the odontogenic epithelial cell by Thymosin beta 4 gene introductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Thymosin beta 4 is associated with RUNX2 expression via the Smad and Akt signaling pathways in mouse dental epithelial cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Itm2a expression in the developing mouse first lower molar, and the subcellular localization of itm2a in mouse dental epithelial cells.2014

Author(s)

Journal Title

Data Source

[Journal Article] Induction of dental epithelial cell differentiation marker gene expression in non-odontogenic human keratinocytes by transfection with thymosin beta 4.2013

Author(s)

Journal Title

Data Source

[Journal Article] Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 硬組織形成期歯胚におけるGlucose regulated protein-78タンパクの発現局在について2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Immunoexpression of glucose regulated protein-78 in the mouse molar and incisor teeth during tooth development2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] V-ATPase 阻害剤 Concanamycin A 抵抗性口腔扁平上皮癌細胞株に対する SAHA 併用による細胞増殖抑制効果2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 非歯原性上皮細胞へのThymosin beta 4 遺伝子導入による歯原性上皮細胞への誘導2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 扁平上皮癌移植モデルマウスを用いたNetrin-1結合部位欠失DCC遺伝子導入の影響2013

Author(s)

Organizer

Place of Presentation

Data Source

FUJIWARA Hiroaki 藤原弘明