Ban Tatsuma 藩龍馬

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BAN Tatsuma 藩龍馬

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Researcher Number	50635357
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 横浜市立大学, 医学部, 講師 2013 – 2018: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related
Keywords	Principal Investigator IRF5 / 自己免疫疾患 / 転写因子 / 全身性エリテマトーデス / 自然免疫応答 / 自己免疫関連B細胞 (ABC) / 免疫学 / 全身性エリテマトーデス (SLE) / MAPキナーゼ / 翻訳後修飾

転写因子IRF5を介した自己免疫関連B細胞の生成メカニズムの解明Principal Investigator
- Principal Investigator
  
  藩龍馬
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Yokohama City University
Understanding the mechanisms of IRF5-selective regulation towards the development of novel SLE treatmentPrincipal Investigator
- Principal Investigator
  
  Ban Tatsuma
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Yokohama City University
Understanding the novel regulatory mechanism of transcription factors in innate immune responsesPrincipal Investigator
- Principal Investigator
  
  BAN Tatsuma
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Yokohama City University

All 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] TLR-MyD88経路と全身性エリテマトーデスにおける転写因子IRF5の制御と役割2018
- Author(s)
  藩龍馬, 田村智彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 1185-1191
- Data Source
  KAKENHI-PROJECT-16K19161
[Journal Article] Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus2018
- Author(s)
  Ban T, Sato GR, Tamura T
- Journal Title
  
  Int Immunol
  
  Volume: 30 Issue: 11 Pages: 529-536
- DOI
  10.1093/intimm/dxy032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19161
[Journal Article] 全身性エリテマトーデスの治療法開発に向けた自然免疫応答制御機構の解明2018
- Author(s)
  藩龍馬
- Journal Title
  
  横浜医学
  
  Volume: 69 Pages: 59-65
- Data Source
  KAKENHI-PROJECT-16K19161
[Journal Article] 転写因子IRF5の活性を選択的に阻害する分子Lynの同定と全身性エリテマトーデス2017
- Author(s)
  藩龍馬, 田村智彦
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 67 Pages: 532-538
- NAID
  40021211284
- Data Source
  KAKENHI-PROJECT-16K19161
[Journal Article] Phos-tag Immunoblot Analysis for Detecting IRF5 Phosphorylation2017
- Author(s)
  Sato GR, Ban T, Tamura T
- Journal Title
  
  Bio-protocol
  
  Volume: 7 Issue: 10
- DOI
  10.21769/bioprotoc.2295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19161
[Journal Article] Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.2016
- Author(s)
  Ban T., Sato G.R., Nishiyama A., Akiyama A., Takasuna M., Umehara M., Suzuki S., Ichino M., Matsunaga S., Kimura A., Kimura Y., Yanai H., Miyashita S., Kuromitsu J., Tsukahara K., Yoshimatsu K., Endo I., Yamamoto T., Hirano H., Ryo A., Taniguchi T., Tamura T.
- Journal Title
  
  Immunity
  
  Volume: 45 Issue: 2 Pages: 319-332
- DOI
  10.1016/j.immuni.2016.07.015
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H07105, KAKENHI-PROJECT-26460373, KAKENHI-PROJECT-15K19028, KAKENHI-PROJECT-16K19161, KAKENHI-PROJECT-16H05230, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04860
[Journal Article] LynはToll様受容体-MyD88シグナル伝達経路において転写因子IRF5を抑制することにより自己免疫疾患の発症を阻止する2016
- Author(s)
  藩龍馬, 田村智彦
- Journal Title
  
  First Author's
  
  Volume: － Pages: 089
- DOI
  10.7875/first.author.2016.089
- Open Access
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] IRF5 as a potent target beyond type I interferons for the next stage SLE therapy2018
- Author(s)
  Kikuchi M, Ban T, Sato GR, Manabe A, Yoshimi R, Yanai H, Taniguchi T, Ito S, Tamura T
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] Stepwise and mutual activation of enhancers and promoters during cell differentiation2018
- Author(s)
  Nishiyama A, Ban T, Fushimi K, Nakabayashi J, Kurotaki D, Tamura T
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] IRF5 as a potent target beyond type I interferons for the next stage SLE therapy2018
- Author(s)
  Kikuchi M, Ban T, Sato GR, Manabe A, Yoshimi R, Yanai H, Taniguchi T, Ito S, Tamura T
- Organizer
  第2回東京理科大-横浜市大合同シンポジウム
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] Selective suppression of IRF5 activity by Lyn in the TLR-MyD88 pathway restrains the development of SLE-like disease2017
- Author(s)
  Ban T, Sato GR, Nishiyama A, Matsunaga S, Kimura A, Kimura Y, Yanai H, Matsumoto Y, Hihara H, Yamamoto T, Hirano H, Ryo A, Tsukahara K, Yoshimatsu K, Taniguchi T, Tamura T
- Organizer
  Cytokines 2017 (5th Annual Meeting of the International Cytokine & Interferon Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] LynはTLR-MyD88経路において転写因子IRF5の活性化を抑制することで自己免疫の発症を阻止する2017
- Author(s)
  藩龍馬，佐藤豪，田村智彦
- Organizer
  第13回麒麟塾
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] Lyn suppresses IRF5 by preventing the stepwise IRF5 post-translational modifications2016
- Author(s)
  Sato GR, Ban T, Nishiyama A, Ichino M, Yanai H, Ryo A, Taniguchi T, Tamura T
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター・ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] IRF5 hyperactivation caused by Lyn deficiency is linked to the development of SLE-like disease2016
- Author(s)
  Ban T, Sato GR, Nishiyama A, Ichino M, Yanai H, Ryo A, Taniguchi T, Tamura T
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター・ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] A critical link between Lyn-mediated suppression of the TLR-MyD88-IRF5 pathway and the development of SLE-like disease2016
- Author(s)
  Ban T, Sato GR, Nishiyama A, Akiyama A, Takasuna M, Umehara M, Suzuki S, Ichino M, Matsunaga S, Kimura A, Kimura Y, Yanai H, Miyashita S, Kuromitsu J, Tsukahara K, Yoshimatsu K, Endo I, Yamamoto T, Hirano H, Ryo A, Taniguchi T, Tamura T
- Organizer
  The Annual Meeting of the American Association of Immunologists 2016
- Place of Presentation
  Seattle (USA)
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] 免疫系転写因子IRF5による転写活性化の新規調節機構とその破綻による自己免疫疾患の発症2016
- Author(s)
  佐藤豪, 藩龍馬, 西山晃, 田村智彦
- Organizer
  新学術領域研究「転写サイクル」班会議
- Place of Presentation
  松島一の坊（宮城県宮城郡松島町）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-16K19161
[Presentation] SrcファミリーキナーゼLynによる転写因子IRF5の抑制と全身性エリテマトーデス（SLE）様病態発症との関わり2015
- Author(s)
  藩龍馬，佐藤豪，西山晃，田村智彦
- Organizer
  第17回神奈川血液・免疫フォーラム
- Place of Presentation
  小田急ホテルセンチュリー相模大野（神奈川県相模原市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25860368
[Presentation] 免疫系転写因子の翻訳後修飾と機能解析を基盤とした自己免疫疾患およびがんの病態解明と治療法開発2015
- Author(s)
  藩龍馬，佐藤豪，西山晃，松永智子，梁明秀，木村鮎子，木村弥生，平野久，宮下定一，黒光淳郎，塚原克平，吉松賢太郎，田村智彦
- Organizer
  イノベーションシステム整備事業「翻訳後修飾プロテオミクス医療研究拠点の形成」第6回シンポジウム
- Place of Presentation
  横浜市立大学（神奈川県横浜市）
- Year and Date
  2015-10-19
- Data Source
  KAKENHI-PROJECT-25860368
[Presentation] Suppression of the TLR-MyD88-IRF5 pathway by the non-receptor type tyrosine kinase Lyn: A critical link to the pathogenesis of SLE2014
- Author(s)
  Tatsuma Ban, Go R. Sato, Akira Nishiyama, Marie Takasuna, Shinsuke Suzuki, Motohide Ichino, Hideyuki Yanai, Akihide Ryo, Tadatsugu Taniguchi and Tomohiko Tamura
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府）
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25860368

1. TAMURA Tomohiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. NISHIYAMA Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. SATO Go

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. KIKUCHI Masako

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MANABE Akio

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YANAI Hideyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 谷口維紹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山本一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ban Tatsuma 藩 龍馬

BAN Tatsuma 藩 龍馬

Research Projects

Research Products

Co-Researchers

転写因子IRF5を介した自己免疫関連B細胞の生成メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the mechanisms of IRF5-selective regulation towards the development of novel SLE treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding the novel regulatory mechanism of transcription factors in innate immune responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TLR-MyD88経路と全身性エリテマトーデスにおける転写因子IRF5の制御と役割2018

Author(s)

Journal Title

Data Source

[Journal Article] Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 全身性エリテマトーデスの治療法開発に向けた自然免疫応答制御機構の解明2018

Author(s)

Journal Title

Data Source

[Journal Article] 転写因子IRF5の活性を選択的に阻害する分子Lynの同定と全身性エリテマトーデス2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Phos-tag Immunoblot Analysis for Detecting IRF5 Phosphorylation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LynはToll様受容体-MyD88シグナル伝達経路において転写因子IRF5を抑制することにより自己免疫疾患の発症を阻止する2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] IRF5 as a potent target beyond type I interferons for the next stage SLE therapy2018

Author(s)

Organizer

Data Source

[Presentation] Stepwise and mutual activation of enhancers and promoters during cell differentiation2018

Author(s)

Organizer

Data Source

[Presentation] IRF5 as a potent target beyond type I interferons for the next stage SLE therapy2018

Author(s)

Organizer

Data Source

[Presentation] Selective suppression of IRF5 activity by Lyn in the TLR-MyD88 pathway restrains the development of SLE-like disease2017

Author(s)

Organizer

Data Source

[Presentation] LynはTLR-MyD88経路において転写因子IRF5の活性化を抑制することで自己免疫の発症を阻止する2017

Author(s)

Organizer

Data Source

[Presentation] Lyn suppresses IRF5 by preventing the stepwise IRF5 post-translational modifications2016

Author(s)

Organizer

Place of Presentation

Ban Tatsuma 藩龍馬

BAN Tatsuma 藩龍馬