Hira Daiki 平大樹

Researcher Number	50636959
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 講師 2022: 京都大学, 医学研究科, 助教 2022: 京都大学, 医学研究科, 講師 2021: 京都大学, 医学研究科, 特定助教 2017 – 2020: 立命館大学, 薬学部, 助教 2013 – 2016: 滋賀医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 個別医療 / 薬物動態 / ファーマコゲノミクス / 遺伝子多型 / 薬力学 / 疼痛管理 / 遺伝子検査 / 医療薬学 / 遺伝子多型解析 / 関節リウマチ / トファシチニブ … More Except Principal Investigator … More 薬物動態 / 網羅的解析 / 遺伝子多型 / ゲノム薬理学 / 母集団解析 / 個別化投与設計 / 薬理ゲノム解析 / PK/PD解析 / 母集団薬物速度論 / 第Xa因子阻害薬 / 薬学 / 個別医療 Less

Clinical utility and safety of pre-emptive pharmacogenomic panel analysis
- Principal Investigator
  
  寺田智祐
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto University
Precision medicine based on real-world clinical pharmacogenomics databasePrincipal Investigator
- Principal Investigator
  
  Hira Daiki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto University
  Ritsumeikan University
Usefulness of Pharmacogenomics in Clinical PracticePrincipal Investigator
- Principal Investigator
  
  Hira Daiki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Pharmacokinetic and pharmacodynamic analysis of oral direct inhibitors of activated coagulation factor X for application to individualized pharmacotherapy
- Principal Investigator
  
  Ueshima Satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Ritsumeikan University
Individual dose of tofacitinib based on pharmacokinetic and pharmacogenomic analysisPrincipal Investigator
- Principal Investigator
  
  Hira Daiki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Shiga University of Medical Science
Pharmacokinetics and pharmacodynamics of novel antihyperuricemic drug.
- Principal Investigator
  
  Terada Tomohiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Shiga University of Medical Science

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Single-Nucleotide Polymorphisms, c.415C > T (Arg139Cys) and c.416G > A (Arg139His), in the <i>NUDT15</i> Gene Are Associated with Thiopurine-Induced Leukopenia2023
- Author(s)
  Isono Tetsuichiro、Hira Daiki、Ikeda Yoshito、Kawahara Masahiro、Noda Satoshi、Nishida Atsushi、Inatomi Osamu、Fujimoto Noriki、Andoh Akira、Terada Tomohiro、Morita Shin-ya
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 3 Pages: 412-418
- DOI
  10.1248/bpb.b22-00686
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06665, KAKENHI-PROJECT-20K07211, KAKENHI-PROJECT-20K16042
[Journal Article] Incorrect holding angle of dry powder inhaler during the drug-loading step significantly decreases output efficiency2021
- Author(s)
  Kana Suenaga, Daiki Hira, Eri Ishido, Hiroyoshi Koide, Satoshi Ueshima, Tomoyuki Okuda, Masafumi Yamaguchi, Shin-ya Morita, Hirokazu Okamoto, Tomonobu Okano, Yasutaka Nakano, Tomohiro Terada, and Mikio Kakumoto
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 44 (6) Pages: 1-9
- NAID
  130008046714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07211
[Journal Article] Effects of antiepileptic drugs’ administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells2021
- Author(s)
  Mikio Kakumoto, Kosuke Shimokawa, Satoshi Ueshima, Daiki Hira,Tomonobu Okano
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 554 Pages: 151-157
- DOI
  10.1016/j.bbrc.2021.03.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-20K07211
[Journal Article] Impact of silicone oil tamponade on intravitreally injected vancomycin pharmacokinetics in cynomolgus monkey eyes2021
- Author(s)
  Hira Daiki、Kitagawa Tomoya、Imamura Taku、Kakinoki Masashi、Ueshima Satoshi、Okano Tomonobu、Ohji Masahito、Kakumoto Mikio、Terada Tomohiro
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 609 Pages: 121185-121185
- DOI
  10.1016/j.ijpharm.2021.121185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-20K07211
[Journal Article] Urine volume to hydration volume ratio is associated with pharmacokinetics of high‐dose methotrexate in patients with primary central nervous system lymphoma2021
- Author(s)
  Isono Tetsuichiro、Hira Daiki、Morikochi Aya、Fukami Tadateru、Ueshima Satoshi、Nozaki Kazuhiko、Terada Tomohiro、Morita Shin‐ya
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 9 Issue: 6
- DOI
  10.1002/prp2.883
- NAID
  120007174617
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-20K07211
[Journal Article] Is “Slow Inhalation” Always Suitable for Pressurized Metered Dose Inhaler?2020
- Author(s)
  Hira Daiki, Okuda Tomoyuki, Mizutani Ayano, Tomida Nao, Mizuno Megumi, Ueshima Satoshi, Kakumoto Mikio, Okano Tomonobu, Okamoto Hirokazu
- Journal Title
  
  AAPS PharmSciTech
  
  Volume: 21 Issue: 2 Pages: 53-53
- DOI
  10.1208/s12249-019-1610-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-17K15504
[Journal Article] 薬学的視点に基づいたプレシジョン・メディシンの国内基盤構築のための調査研究2020
- Author(s)
  辻大樹、斎藤嘉朗、莚田泰誠、三浦昌朋、平大樹、寺田智祐
- Journal Title
  
  医療薬学
  
  Volume: 46 Pages: 66-76
- NAID
  130007983444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Genetic variants of alcohol‐metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol2019
- Author(s)
  Wu Qi、Hayashi Hideki、Hira Daiki、Sonoda Keiko、Ueshima Satoshi、Ohno Seiko、Makiyama Takeru、Terada Tomohiro、Katsura Toshiya、Miura Katsuyuki、Horie Minoru
- Journal Title
  
  Journal of Arrhythmia
  
  Volume: 35 Issue: 5 Pages: 752-759
- DOI
  10.1002/joa3.12227
- NAID
  120006848263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K15504
[Journal Article] Low Body Mass Index and Myeloablative Conditioning Regimen Prolong the Duration of Parenteral Nutrition During Hematopoietic Stem Cell Transplantation2019
- Author(s)
  Kamiya Takaki、Hira Daiki、Hoshino Nobuo、Kurihara Mika、Nakagawa Mayumi、Sasaki Masaya、Terada Tomohiro
- Journal Title
  
  Annals of Nutrition and Metabolism
  
  Volume: 74 Issue: 2 Pages: 107-114
- DOI
  10.1159/000496457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Population pharmacokinetics and pharmacodynamics of apixaban linking its plasma concentration to intrinsic activated coagulation factor X activity in Japanese patients with atrial fibrillation2019
- Author(s)
  Ueshima Satoshi、Hira Daiki、Tomitsuka Chiho、Nomura Miki、Kimura Yuuma、Yamane Takuya、Tabuchi Yohei、Ozawa Tomoya、Itoh Hideki、Horie Minoru、Terada Tomohiro、Katsura Toshiya
- Journal Title
  
  The AAPS Journal
  
  Volume: 21 Issue: 5 Pages: 80-80
- DOI
  10.1208/s12248-019-0353-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-19K07234, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K15504
[Journal Article] Exploratory Investigation of Target Pazopanib Concentration Range for Patients With Renal Cell Carcinoma2019
- Author(s)
  Satoshi Noda, Tetsuya Yoshida, Daiki Hira, Ryosuke Murai, Keiji Tomita, Teruhiko Tsuru, Susumu Kageyama, Akihiro Kawauchi, Yoshito Ikeda, Shin-ya Morita, Tomohiro Terada.
- Journal Title
  
  Clinical Genitourinary Cancer
  
  Volume: 17 Issue: 2 Pages: e306-e313
- DOI
  10.1016/j.clgc.2018.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-17K15504
[Journal Article] Concomitant administration of candesartan cilexetil in patients on paclitaxel and carboplatin combination therapy increases risk of severe neutropenia2018
- Author(s)
  Katsube Yurie、Hira Daiki、Tsujimoto Masayuki、Koide Hiroyoshi、Minegaki Tetsuya、Ikeda Yoshito、Morita Shin-ya、Nishiguchi Kohshi、Terada Tomohiro
- Journal Title
  
  Int. Journal of Clinical Pharmacology and Therapeutics
  
  Volume: 56 Issue: 07 Pages: 328-336
- DOI
  10.5414/cp203180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline2018
- Author(s)
  Daiki Hira, Asami Suzuki, Yusuke Kono, Kosuke Shimokawa, Serika Matsuoka, Ken-yuh Hasumoto, Hiroyuki Kawahara, Masahide Onoue, Takuya Fujita, Tomonobu Okano and Mikio Kakumoto
- Journal Title
  
  J. Pharm. Health Care Sci.
  
  Volume: 4 Issue: 1 Pages: 1-6
- DOI
  10.1186/s40780-018-0116-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08430, KAKENHI-PROJECT-17K15438, KAKENHI-PROJECT-17K15504
[Journal Article] In-vitro evaluation of optimal inhalation flow patterns for commercial dry powder inhalers and pressurized metered dose inhalers with human inhalation flow pattern simulator2018
- Author(s)
  Hira Daiki、Okuda Tomoyuki、Mizutani Ayano、Tomida Nao、Okamoto Hirokazu
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 107 Issue: 6 Pages: 1731-1735
- DOI
  10.1016/j.xphs.2018.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Assessment of inhalation flow patterns of soft mist inhaler co-prescribed with dry powder inhaler using inspiratory flow meter for multi inhalation devices2018
- Author(s)
  Hira Daiki、Koide Hiroyoshi、Nakamura Shigemi、Okada Toyoko、Ishizeki Kazunori、Yamaguchi Masafumi、Koshiyama Setsuko、Oguma Tetsuya、Ito Kayoko、Funayama Saori、Komase Yuko、Morita Shin-ya、Nishiguchi Kohshi、Nakano Yasutaka、Terada Tomohiro
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 2 Pages: e0193082-e0193082
- DOI
  10.1371/journal.pone.0193082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] BCRP/ABCG2 and high-alert medications: Biochemical, pharmacokinetic, pharmacogenetic, and clinical implications.2018
- Author(s)
  Hira D, Terada T.
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 147 Pages: 201-210
- DOI
  10.1016/j.bcp.2017.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-18K06782
[Journal Article] Effect of nasally exhaling budesonide/formoterol dry powder inhaled at “fast” inspiratory flow on eosinophilic chronic rhinosinusitis2018
- Author(s)
  Hamada Satoshi、Hira Daiki、Kobayashi Yoshiki、Yasuba Hirotaka
- Journal Title
  
  Int. Journal of Clinical Pharmacology and Therapeutics
  
  Volume: 56 Issue: 11 Pages: 539-543
- DOI
  10.5414/cp203272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation.2018
- Author(s)
  Ueshima S, Hira D, Kimura Y, Fujii R, Tomitsuka C, Yamane T, Tabuchi Y, Ozawa T, Itoh H, Ohno S, Horie M, Terada T, Katsura T.
- Journal Title
  
  Br. J. Clin. Pharmacol.
  
  Volume: - Issue: 6 Pages: 1301-1312
- DOI
  10.1111/bcp.13561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-17K15528, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K06766, KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-15K08114
[Journal Article] Systematic review of salivary versus blood concentrations of antituberculosis drugs and their potential for salivary therapeutic drug monitoring.2018
- Author(s)
  van den Elsen Simone H.J.、Oostenbrink Lisette M.、Heysell Scott K.、Hira Daiki、Touw Daan J.、Akkerman Onno W.、Bolhuis Mathieu S.、Alffenaar Jan-Willem C.
- Journal Title
  
  Therapeutic Drug Monitoring
  
  Volume: 40 Issue: 1 Pages: 17-37
- DOI
  10.1097/ftd.0000000000000462
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15504
[Journal Article] Oral mucositis associated with anti-EGFR therapy in colorectal cancer: single institutional retrospective cohort study2018
- Author(s)
  Dote Satoshi、Itakura Shoji、Kamei Kohei、Hira Daiki、Noda Satoshi、Kobayashi Yuka、Terada Tomohiro
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 957-957
- DOI
  10.1186/s12885-018-4862-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06782, KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-18H00400
[Journal Article] Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation2017
- Author(s)
  Satoshi Ueshima, Daiki Hira, Ryo Fujii, Yuuma Kimura, Chiho Tomitsuka, Takuya Yamane, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Minoru Horie, Tomohiro Terada, Toshiya Katsura
- Journal Title
  
  Pharmacogenetics and Genomics
  
  Volume: 27 Issue: 9 Pages: 329-336
- DOI
  10.1097/fpc.0000000000000294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08114, KAKENHI-PROJECT-17K09494, KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-17K15528, KAKENHI-PROJECT-15H04818
[Journal Article] Letter: CYP3A4/5 genotype status and outcome of vonoprazan-containing Helicobacter pylori eradication therapy in Japan.2017
- Author(s)
  Sugimoto M, Ban H, Hira D, Kamiya T, Otsuka T, Inatomi O, Bamba S, Terada T, Andoh A.
- Journal Title
  
  Aliment Pharmacol Ther.
  
  Volume: 45 Issue: 7 Pages: 1009-1010
- DOI
  10.1111/apt.13959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460966, KAKENHI-PROJECT-26860100, KAKENHI-PROJECT-16K08787, KAKENHI-PROJECT-17K15504, KAKENHI-PROJECT-15K08948, KAKENHI-PROJECT-17H00518
[Journal Article] Previous Dosage of Allopurinol Is a Strong Determinant of Febuxostat Efficacy2017
- Author(s)
  Koide H, Hira D, Tsujimoto M, Katsube Y, Minegaki T, Uzu T, Ikeda Y, Morita SY, Nishiguchi K, Terada T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 5 Pages: 681-686
- DOI
  10.1248/bpb.b16-00972
- NAID
  130005631961
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860100
[Journal Article] Pharmacokinetic analysis of a hemodialyzed patient treated with pazopanib.2016
- Author(s)
  S. Noda, D. Hira, S. Kageyama, (他6名)
- Journal Title
  
  Clinical Genitourinary Cancer
  
  Volume: 14(4) Issue: 4 Pages: e453-e456
- DOI
  10.1016/j.clgc.2016.03.016
- Description
  in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H00499, KAKENHI-PROJECT-26860100
[Journal Article] Assessment of Sunitinib-Induced Toxicities and Clinical Outcomes Based on Therapeutic Drug Monitoring of Sunitinib for Patients With Renal Cell Carcinoma. Clin Genitourin Cancer.2015
- Author(s)
  Noda S, Otsuji T, Baba M, Yoshida T, Kageyama S, Okamoto K, Okada Y, Kawauchi A, Onishi H, Hira D, Morita SY, Terada T
- Journal Title
  
  Clinical Genitourinary Cancer
  
  Volume: in press Issue: 4 Pages: 350-358
- DOI
  10.1016/j.clgc.2015.01.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592384, KAKENHI-PROJECT-25460187, KAKENHI-PROJECT-26860100
[Journal Article] Population pharmacokinetics and therapeutic efficacy of febuxostat in patients with severe renal impairment.2015
- Author(s)
  Daiki Hira, Yugo Chisaki, Satoshi Noda, Hisazumi Araki, Takashi Uzu, Hiroshi Maegawa, Yoshitaka Yano, Shin-ya Morita, and Tomohiro Terada.
- Journal Title
  
  Pharmacology
  
  Volume: 96 Issue: 1-2 Pages: 90-98
- DOI
  10.1159/000434633
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860100, KAKENHI-PROJECT-25460187
[Journal Article] Intestinal and hepatic drug transporters: pharmacokinetic, pathophysiological, and pharmacogenetic roles.2015
- Author(s)
  Tomohiro Terada, Daiki Hira.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: .
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460187
[Journal Article] Intestinal and hepatic drug transporters: pharmacokinetic, pathophysiological, and pharmacogenetic roles.2015
- Author(s)
  Tomohiro Terada, Daiki Hira.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 50 Issue: 5 Pages: 508-519
- DOI
  10.1007/s00535-015-1061-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860100, KAKENHI-PROJECT-25460187
[Journal Article] Reduction in gastrointestinal toxicity during S-1 monotherapy for patients with gastric cancer by gastric secretion inhibitors.2014
- Author(s)
  Yugo Chisaki, Satoshi Noda, Daiki Hira, Shin-ya Morita, Yoshitaka Yano, Tomohiro Terada.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37 Pages: 1158-1161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460187
[Journal Article] Reduction in gastrointestinal toxicity during S-1 monotherapy for patients with gastric cancer by gastric secretion inhibitors.2014
- Author(s)
  Yugo Chisaki, Satoshi Noda, Daiki Hira, Shin-ya Morita, Yoshitaka Yano, Tomohiro Terada.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37 Pages: 1158-1161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860100
[Presentation] 抗凝固薬内服者の消化器診療とPharmacogenomicsの重要性.2022
- Author(s)
  平大樹, 上島智, 桂敏也, 寺田智祐
- Organizer
  JPW2022 (第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会)
- Invited
- Data Source
  KAKENHI-PROJECT-20K07211
[Presentation] Simultaneous quantification of 15 inhalants in exhaled breath for confirmation of adequate inhalation.2022
- Author(s)
  Daiki Hira, Shunsaku Nakagawa, Kotaro Itohara, Sakiko Hatazoe, Satoshi Imai, Satoshi Ueshima, Atsushi Yonezawa, Takayuki Nakagawa, Tomonobu Okano, Mikio Kakumoto, Tomohiro Terada
- Organizer
  20th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07211
[Presentation] 腎を主軸とした臨床研究の経験と期待.2022
- Author(s)
  平大樹, 國津侑貴, 幾田慧子, 中川俊作, 森田真也, 寺田智祐
- Organizer
  第16回日本腎臓病薬物療法学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07211
[Presentation] 実臨床における薬物動態関連遺伝子多型検査の活用事例2021
- Author(s)
  平　大樹, 森田真也, 寺田智祐
- Organizer
  第61回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07211
[Presentation] トラマドールの鎮痛効果におけるCYP2D6遺伝子多型測定の臨床的意義2019
- Author(s)
  神谷貴樹、中島亮、平大樹、元持杏津子、森河内彩、篠田和葉、米田真悟、今井晋二、寺田智祐
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] 日本人におけるトラマドールの鎮痛効果に及ぼすCYP2D6遺伝子型の影響2019
- Author(s)
  篠田和葉、神谷貴樹、平　大樹、岩下成人、中島　亮、上島　智、角本幹夫、今井晋二、福井　聖、寺田智祐
- Organizer
  第3回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] 実臨床におけるファーマコゲノミクス検査の活用状況2019
- Author(s)
  平　大樹、辻大樹、齋藤嘉朗、莚田泰誠、三浦昌朋、寺田智祐
- Organizer
  第29回日本医療薬学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] CYP2D6遺伝子型に応じた鎮痛薬トラマドールの個別投与法に関するレトロスペクティブ解析2019
- Author(s)
  神谷貴樹、中島亮、平大樹、森河内彩、元持杏津子、篠田和葉、米田真悟、今井晋二、寺田智祐
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] 薬物代謝酵素の遺伝子多型測定に基づくトラマドールの個別化投与設計2018
- Author(s)
  平　大樹, 岩下成人, 神谷貴樹, 中島　亮, 磯野哲一郎, 赤羽理也, 池田義人, 角本幹夫, 森田真也, 岡野友信, 今井晋二, 福井　聖, 寺田智祐
- Organizer
  第40回　日本疼痛学会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] ファーマコゲノミクス検査に基づいた抗血小板薬選択の実態調査（優秀発表賞受賞）2018
- Author(s)
  磯野哲一郎, 平　大樹, 福井里佳, 田淵陽平, 赤羽理也, 池田義人, 森田真也, 寺田智祐
- Organizer
  第35回日本TDM学会学術大会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] ファーマコゲノミクス検査の臨床実装2018
- Author(s)
  寺田智祐, 平　大樹
- Organizer
  第35回日本TDM学会学術大会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] 実臨床における薬効・薬物動態評価のためのファーマコメトリクスの活用2017
- Author(s)
  平　大樹, 寺田　智祐
- Organizer
  第27回　日本医療薬学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] トラマドールの個別化投与設計を目指したCYP2D6遺伝子多型測定体制の構築2017
- Author(s)
  平　大樹, 岩下成人, 神谷貴樹, 中島　亮, 磯野哲一郎, 赤羽理也, 森田真也, 今井晋二, 福井　聖, 寺田智祐
- Organizer
  第39回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] 経口抗凝固薬の副作用と血中薬物濃度に及ぼす薬物動態関連遺伝子多型の影響2017
- Author(s)
  平　大樹、上島　智、伊藤英樹、小澤友哉、堀江　稔、桂　敏也、寺田智祐
- Organizer
  第33回滋賀医科大学シンポジウム
- Place of Presentation
  滋賀医科大学 (滋賀県大津市)
- Year and Date
  2017-02-21
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] Pharmacogenomics in Clinical Practice2017
- Author(s)
  Daiki Hira, Tomohiro Terada
- Organizer
  15th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15504
[Presentation] Pharmacometrics in clinical practice: Population PK analysis of febuxostat in patients with severe renal impairment2016
- Author(s)
  Daiki Hira, Tomohiro Terada
- Organizer
  The 2nd A3 Pharmcometrics Symposium
- Place of Presentation
  Daejeon, Republic of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860100
[Presentation] アピキサバンの血中濃度と血液凝固活性に関する速度論的解析2016
- Author(s)
  冨塚知歩、上島　智、平　大樹、野村実希、木村悠馬、山根拓也、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2016
- Place of Presentation
  ピアザ淡海 (滋賀県草津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] 腎機能低下患者におけるフェブキソスタットの臨床薬理学的研究2016
- Author(s)
  平　大樹
- Organizer
  腎疾患と高尿酸血症セミナー2016
- Place of Presentation
  ボストンプラザホテル草津
- Year and Date
  2016-01-30
- Data Source
  KAKENHI-PROJECT-25460187
[Presentation] 院内におけるPGｘ検査の体制構築に向けた取組みについて2016
- Author(s)
  平　大樹, 寺田智祐
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  京都
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-26860100
[Presentation] アピキサバン服用患者における出血症状と血中薬物濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  上島智、平大樹、藤井亮、木村悠馬、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江稔、寺田智祐、桂敏也
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] アピキサバンの血中トラフ濃度に及ぼす薬物動態関連遺伝子多型の影響2016
- Author(s)
  木村悠馬、上島　智、平　大樹、藤井　亮、冨塚知歩、山根拓也、伊藤英樹、小澤友哉、堀江　稔、寺田智祐、桂　敏也
- Organizer
  医療薬学フォーラム2016
- Place of Presentation
  ピアザ淡海 (滋賀県草津市)
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K18938
[Presentation] フェブキソスタットの尿酸低下作用に及ぼす患者背景因子の探索2016
- Author(s)
  小出博義, 平　大樹, 辻本雅之, 峯垣哲也, 森田真也, 西口工司, 寺田智祐
- Organizer
  日本薬学会　第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25460187
[Presentation] 経口関節リウマチ分子標的薬の薬物動態影響因子の探索2015
- Author(s)
  平　大樹, 寺田智祐
- Organizer
  平成26年度学長裁量経費による研究助成成果発表会
- Place of Presentation
  滋賀医科大学
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26860100
[Presentation] CKD患者におけるフェブキソスタットの薬物動態解析2015
- Author(s)
  寺田智祐, 平　大樹, 地嵜悠吾, 野田哲史, 宇津　貴, 前川　聡, 矢野義孝, 森田真也
- Organizer
  第58回日本腎臓学会, 2015年6月 (名古屋)
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-25460187
[Presentation] フェブキソスタットの代謝経路の同定とその臨床的な影響の評価2013
- Author(s)
  平　大樹他
- Organizer
  医療薬学フォーラム2013/第21回クリニカルファーマシーシンポジウム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25460187
[Presentation] 高度腎機能低下患者における高尿酸血症治療薬フェブキソスタットの薬物動態解析
- Author(s)
  平　大樹，森田真也，寺田智祐
- Organizer
  第30回滋賀医科大学シンポジウム
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-25460187
[Presentation] 高度腎機能低下患者におけるフェブキソスタットの薬物動態、治療効果の解析
- Author(s)
  平大樹, 地嵜悠吾, 野田哲史, 宇津貴, 前川聡, 矢野義孝, 森田真也, 寺田智祐
- Organizer
  医療薬学フォーラム 2014
- Place of Presentation
  東京
- Year and Date
  2014-06-28 – 2014-06-29
- Data Source
  KAKENHI-PROJECT-26860100
[Presentation] 高尿酸血症治療薬フェブキソスタットの薬物動態/薬力学的研究
- Author(s)
  平　大樹
- Organizer
  第2回腎疾患と高尿酸血症セミナー
- Place of Presentation
  草津
- Invited
- Data Source
  KAKENHI-PROJECT-25460187

1. Terada Tomohiro (10324641)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. Ueshima Satoshi (70734771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. Katsura Toshiya (10283615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. Horie Minoru (90183938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 中川俊作 (50721916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. BAMBA Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 影山進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 河内明宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 藤田卓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 伴宏充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 池田義人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hira Daiki 平 大樹

Research Projects

Research Products

Co-Researchers

Clinical utility and safety of pre-emptive pharmacogenomic panel analysis

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Precision medicine based on real-world clinical pharmacogenomics databasePrincipal Investigator

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Usefulness of Pharmacogenomics in Clinical PracticePrincipal Investigator

Principal Investigator

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Pharmacokinetic and pharmacodynamic analysis of oral direct inhibitors of activated coagulation factor X for application to individualized pharmacotherapy

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Individual dose of tofacitinib based on pharmacokinetic and pharmacogenomic analysisPrincipal Investigator

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Pharmacokinetics and pharmacodynamics of novel antihyperuricemic drug.

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[Journal Article] Single-Nucleotide Polymorphisms, c.415C &gt; T (Arg139Cys) and c.416G &gt; A (Arg139His), in the <i>NUDT15</i> Gene Are Associated with Thiopurine-Induced Leukopenia2023

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[Journal Article] Incorrect holding angle of dry powder inhaler during the drug-loading step significantly decreases output efficiency2021

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NAID

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[Journal Article] Effects of antiepileptic drugs’ administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells2021

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[Journal Article] Impact of silicone oil tamponade on intravitreally injected vancomycin pharmacokinetics in cynomolgus monkey eyes2021

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[Journal Article] Urine volume to hydration volume ratio is associated with pharmacokinetics of high‐dose methotrexate in patients with primary central nervous system lymphoma2021

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NAID

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[Journal Article] Is “Slow Inhalation” Always Suitable for Pressurized Metered Dose Inhaler?2020

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[Journal Article] 薬学的視点に基づいたプレシジョン・メディシンの国内基盤構築のための調査研究2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Genetic variants of alcohol‐metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol2019

Hira Daiki 平大樹

[Journal Article] Single-Nucleotide Polymorphisms, c.415C > T (Arg139Cys) and c.416G > A (Arg139His), in the <i>NUDT15</i> Gene Are Associated with Thiopurine-Induced Leukopenia2023