MURASHIMA AKI 村嶋亜紀

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Murashima Aki 村嶋亜紀

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Researcher Number	50637105
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2025: 和歌山県立医科大学, 先端医学研究所, 特別研究員
Affiliation (based on the past Project Information) *help	2025: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2023: 岐阜薬科大学, 薬学部, 講師 2022: 岩手医科大学, 医学部, 講師 2016 – 2021: 岩手医科大学, 医学部, 助教 2014 – 2015: 和歌山県立医科大学, 先端医学研究所, 特別研究員 2013: 和歌山県立医科大学, 先端医学研究所, 学内助教
Review Section/Research Field	Principal Investigator Basic Section 59030:Physical education, and physical and health education-related / Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) / General medical chemistry / Endocrinology Except Principal Investigator General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 中腎 / 遺伝子改変マウス / 血管形成 / Fgf / アンドロゲン / ウォルフ管 / 細胞増殖因子 / ファシア / 臓器間ネットワーク / 腎臓 … More / 発生 / 下大静脈 / 解剖学 / 比較発生学 / 血管発生 / 還流路形成 / 血管 / 発生学 / マウス / 性分化 / 腎臓発生 / MAPKシグナル / beta-catenin / 尿管芽 / ノックアウトマウス / Wnt/b-catenin / Shh / 生殖内分泌学 / アンドロゲン受容体 … More Except Principal Investigator 老化 / 末梢血単核球 / 生物学的年齢 / メチローム / エピゲノム Less

腎ファシアの解剖学・神経生理学的基盤研究Principal Investigator
- Principal Investigator
  
  村嶋亜紀
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59030:Physical education, and physical and health education-related
- Research Institution
  Nagoya City University
Spaciotemporal analysis for developing inferior vena cavaPrincipal Investigator
- Principal Investigator
  
  Murashima Aki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Gifu Pharmaceutical University
  Iwate Medical University
Genome-wide methylation profiles to develop a predictive model for the human biological age
- Principal Investigator
  
  Hitomi Jiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Iwate Medical University
Analyses for vascular formation during androgen dependent sexual developmentPrincipal Investigator
- Principal Investigator
  
  Murashima Aki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Iwate Medical University
Analysis of molecular mechanisms of the ureteric bud formationPrincipal Investigator
- Principal Investigator
  
  Murashima Aki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Iwate Medical University
  Wakayama Medical University
Molecular mechanisms of masculinization: role of growth factor signaling and androgen regulationPrincipal Investigator
- Principal Investigator
  
  Murashima Aki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Wakayama Medical University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Early development of the pulmonary vascular system: An anatomical and histochemical reinvestigation of the pulmonary venous return development in mice2022
- Author(s)
  Abe Shizuka、Murashima Aki、Kimura Eiji、Ema Masatsugu、Hitomi Jiro
- Journal Title
  
  Acta Histochemica
  
  Volume: 124 Issue: 2 Pages: 151840-151840
- DOI
  10.1016/j.acthis.2021.151840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07229
[Journal Article] New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development2021
- Author(s)
  Haraguchi Ryuma、Yamada Gen、Murashima Aki、Matsumaru Daisuke、Kitazawa Riko、Kitazawa Sohei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1211-1211
- DOI
  10.3390/ijms22031211
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-20K07229, KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-18K06832, KAKENHI-PROJECT-18K06938, KAKENHI-PROJECT-21K06755
[Journal Article] 肺循環の成り立ちと肺静脈形成の形態学的考察2021
- Author(s)
  阿部志津香, 村嶋亜紀, 人見次郎
- Journal Title
  
  岩手医学雑誌
  
  Volume: -
- NAID
  130008139958
- Data Source
  KAKENHI-PROJECT-20K07229
[Journal Article] Radiation inducible MafB gene is required for thymic regeneration2021
- Author(s)
  Daiki Hashimoto, Jose Gabriel R. Colet, Aki Murashima, Kota Fujimoto, Yuko Ueda, Kentaro Suzuki, Taiju Hyuga, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoru Takahashi, Yousuke Takahama and Gen Yamada1
- Journal Title
  
  Scientific Reports
  
  Volume: - Issue: 1 Pages: 10439-10439
- DOI
  10.1038/s41598-021-89836-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07229, KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-18K07071, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-21K06956, KAKENHI-PROJECT-21K19538, KAKENHI-PROJECT-20K18150
[Journal Article] Regulation of masculinization: androgen signalling for external genitalia development2018
- Author(s)
  Matsushita Shoko、Suzuki Kentaro、Murashima Aki、Kajioka Daiki、Acebedo Alvin Resultay、Miyagawa Shinichi、Haraguchi Ryuma、Ogino Yukiko、Yamada Gen
- Journal Title
  
  Nature Reviews Urology
  
  Volume: 印刷中 Issue: 6 Pages: 358-368
- DOI
  10.1038/s41585-018-0008-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-18K06832, KAKENHI-PROJECT-18K06938, KAKENHI-PLANNED-17H06432, KAKENHI-PROJECT-18H02474, KAKENHI-PROJECT-17K18024
[Journal Article] Epispadias and the associated embryopathies; genetic and developmental basis.2017
- Author(s)
  Kentaro Suzuki, Daisuke Matsumaru, Shoko Matsushita, Aki Murashima, Michael Ludwig, Heiko Reuter, Gen Yamada
- Journal Title
  
  Clinical Genetics
  
  Volume: 91 Issue: 2 Pages: 247-253
- DOI
  10.1111/cge.12871
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J11033, KAKENHI-PROJECT-15K10647, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-17K18024, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-16K08595
[Journal Article] Androgen Regulates Dimorphic F-Actin Assemblies in the Genital Organogenesis2017
- Author(s)
  Liu Liqing、Suzuki Kentaro、Chun Eunice、Murashima Aki、Sato Yuki、Nakagata Naomi、Fujimori Toshihiko、Yonemura Shigenobu、He Wanzhong、Yamada Gen
- Journal Title
  
  Sexual Development
  
  Volume: 11 Issue: 4 Pages: 190-202
- DOI
  10.1159/000477452
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-16K14739, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-15K10647, KAKENHI-PROJECT-15K19013
[Journal Article] Developmental Contribution of Wnt-signal-responsive Cells to Mouse Reproductive Tract Formation2017
- Author(s)
  Haraguchi Ryuma, Kitazawa Riko, Murashima Aki, Yamada Gen, Kitazawa Sohei
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 50 Issue: 4 Pages: 127-133
- DOI
  10.1267/ahc.17017
- NAID
  130006003857
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08495, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-15K08136, KAKENHI-PROJECT-15K19013
[Journal Article] マウス初期胚の眼球形成領域の血管形成2017
- Author(s)
  清野太郎，木村英二，村嶋亜紀，黒坂大次郎
- Journal Title
  
  岩手医学雑誌
  
  Volume: 69(5) Pages: 243-253
- NAID
  40021420246
- Data Source
  KAKENHI-PROJECT-17K08495
[Journal Article] ウォルフ管上皮特異的beta-catenin遺伝子ノックアウトマウスの示す異所的尿管芽の病態解析2016
- Author(s)
  﨑田佳嗣, 岡澤美佳, 村嶋亜紀, 山田源
- Journal Title
  
  和歌山医学
  
  Volume: 67(2) Pages: 56-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19013
[Journal Article] Investigation of sexual dimorphisms through mouse models and hormone/hormone-disruptor treatments2016
- Author(s)
  Ipulan LA, Raga D, Suzuki K, Murashima A, Matsumaru D, Cunha G, Yamada G.
- Journal Title
  
  Differentiation
  
  Volume: 印刷中 Issue: 4-5 Pages: 30072-4
- DOI
  10.1016/j.diff.2015.11.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10647, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-16K08595
[Journal Article] ウォルフ管上皮特異的β-catenin 遺伝子ノックアウトマウスの示す異所的尿管芽の病態解析2016
- Author(s)
  﨑田佳嗣, 岡澤-坂井美佳, 村嶋亜紀, 山田源
- Journal Title
  
  和歌山医学
  
  Volume: 67巻2号
- NAID
  40020888999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860771
[Journal Article] ウォルフ管上皮特異的β-catenin遺伝子ノックアウトマウスの示す異所的尿管芽の病態解析2016
- Author(s)
  﨑田佳嗣, 岡澤-坂井美佳, 村嶋亜紀, 山田源
- Journal Title
  
  和歌山医学
  
  Volume: 67巻2号
- NAID
  40020888999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19013
[Journal Article] Systematic stereoscopic analyses for cloacal development: The origin of anorectal malformations.2015
- Author(s)
  Matsumaru D, Murashima A, Fukushima J, Senda S, Matsushita S, Nakagata N, Miyajima M, Yamada G.
- Journal Title
  
  Sci Rep.
  
  Volume: 10;5 Issue: 1 Pages: 13943-13943
- DOI
  10.1038/srep13943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15403, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-26860196, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04300, KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-15J11033
[Journal Article] Understanding normal and abnormal development of the Wolffian/epididymal duct using transgenic mice2015
- Author(s)
  Murashima A, Xu B, Hinton BT
- Journal Title
  
  Asian Journal of Andrology
  
  Volume: 17(5) Issue: 5 Pages: 749-55
- DOI
  10.4103/1008-682x.155540
- Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-25860771
[Journal Article] Region-specific regulation of cell proliferation by Fgf receptor signaling during the Wolffian duct development2015
- Author(s)
  Mika Okazawa, Aki Murashima, Masayo Harada, Naomi Nakagata, Masafumi Noguchi, Mitsuru Morimoto, Tadashi Kimura, David M. Ornitz, Gen Yamada
- Journal Title
  
  Developmental Biology
  
  Volume: 1;400(1) Issue: 1 Pages: 139-147
- DOI
  10.1016/j.ydbio.2015.01.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-15K15403, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04300
[Journal Article] Non-myocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle.2014
- Author(s)
  Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P and Yamada G.
- Journal Title
  
  Endocrinology
  
  Volume: 155(7) Issue: 7 Pages: 2467-79
- DOI
  10.1210/en.2014-1008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-24590235, KAKENHI-PROJECT-25860771
[Journal Article] Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.2014
- Author(s)
  Aki Murashima, Hiroki Akita, Mika Okazawa, Satoshi Kishigami, Naomi Nakagata, Ryuichi Nishinakamura and Gen Yamada.
- Journal Title
  
  Developmental Biology
  
  Volume: 1;386(1) Issue: 1 Pages: 216-26
- DOI
  10.1016/j.ydbio.2013.12.026
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-25860771
[Journal Article] Androgens and mammalian male reproductive tract development2014
- Author(s)
  Aki Murashima, Satoshi Kishigami, Axel Thomson, Gen Yamada
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1849(2) Issue: 2 Pages: 163-170
- DOI
  10.1016/j.bbagrm.2014.05.020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] マウス胎仔における交感神経性パラガングリアの組織発生学的解析2024
- Author(s)
  村嶋亜紀、人見次郎
- Organizer
  第69回薬学会東海支部会
- Data Source
  KAKENHI-PROJECT-20K07229
[Presentation] 免疫組織化学による交感神経および副腎細胞の染色と同定 :マウス胚とサンショウウオを用いて2023
- Author(s)
  村嶋亜紀
- Organizer
  第20回医学生物学電子顕微鏡シンポジウム合同企画第34回医学生物学電子顕微鏡技術研修会および総会
- Data Source
  KAKENHI-PROJECT-20K07229
[Presentation] Morphogenesis of pro to mesonephric vascular system in salamander, Hynobius lichenatus: Micro vasculogenetic analyses with corrosive resin casts2021
- Author(s)
  Aki Murashima
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07229
[Presentation] マウスにおける下大静脈発生の時空間的解析2021
- Author(s)
  村嶋亜紀
- Organizer
  第67回日本解剖学会東北・北海道連合学術支部会
- Data Source
  KAKENHI-PROJECT-20K07229
[Presentation] 薬剤誘導型遺伝子改変マウスを用いた頭部血管発生機構の解析2019
- Author(s)
  村嶋亜紀、及川里百合、木村英二、人見次郎
- Organizer
  第124回　日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K08495
[Presentation] The functions of growth factor signaling in the developing Wolffian duct and male reproductive tract2015
- Author(s)
  Murashima A., Okazawa M., and Yamada G
- Organizer
  7th International Symposium on the Biology of Vertebrate Sex Determination
- Place of Presentation
  Kona, Hawaii, USA
- Year and Date
  2015-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19013
[Presentation] The functions of growth factor signaling in the developing Wolffian duct and male reproductive tract2015
- Author(s)
  Aki Murashima, Mika Okazawa and Gen Yamada
- Organizer
  7th International Symposium on the Biology of Vertebrate Sex Determination
- Place of Presentation
  Kailua-Kona, Hawaii, USA
- Year and Date
  2015-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm2014
- Author(s)
  村嶋亜紀
- Organizer
  第47回日本発生生物学会大会
- Place of Presentation
  ウインクあいち（愛知）
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] The function of growth factor signaling in the developing Wolffian duct and male reproductive tract
- Author(s)
  Aki Murashima, Mika Okazawa, Gen Yamada
- Organizer
  7th International Symposium on the Biology of Vertebrate Sex Determination
- Place of Presentation
  コナ、ハワイ、米国
- Year and Date
  2015-04-13 – 2015-04-17
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] ウォルフ管雄性化過程と精巣上体上皮分化過程におけるアンドロゲンシグナルの機能解析
- Author(s)
  村嶋亜紀
- Organizer
  第32回日本アンドロロジー学会
- Place of Presentation
  グランキューブ大阪（大阪）
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] 線維芽細胞増殖因子受容体（FGFR）シグナリングによる領域特異的なウォルフ管上皮細胞増殖の調節について
- Author(s)
  Mika Okazawa, Aki Murashima, Tadashi Kimura, Gen Yamada
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] 正中構造由来のSonic hedgehogは沿軸中胚葉を介して中腎細管の形成を制御する
- Author(s)
  村嶋亜紀
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫）
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] The functions of growth factor signaling in developing Wolffian duct and male reproductive tract
- Author(s)
  Aki Murashima, Mika Okazawa, Gen Yamada
- Organizer
  6th international conference on the epididymis
- Place of Presentation
  SIBS、上海、中国
- Year and Date
  2014-10-31 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-25860771
[Presentation] Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm
- Author(s)
  Aki Murashima, Hiroki Akita, Mika Okazawa, Satoshi Kishigami, Naomi Nakagata, Ryuichi Nishinakamura, Gen Yamada
- Organizer
  47th Annual Meeting of the JSDB
- Place of Presentation
  ウインク愛知、名古屋
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25860771

1. Hitomi Jiro (00218728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 三上貴浩 (90804419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 丹野高三 (20327026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 寺山靖夫 (70146596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 山田源

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 松下祥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松丸大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURASHIMA AKI 村嶋 亜紀

Murashima Aki 村嶋 亜紀

Research Projects

Research Products

Co-Researchers

腎ファシアの解剖学・神経生理学的基盤研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spaciotemporal analysis for developing inferior vena cavaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome-wide methylation profiles to develop a predictive model for the human biological age

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses for vascular formation during androgen dependent sexual developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanisms of the ureteric bud formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of masculinization: role of growth factor signaling and androgen regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Early development of the pulmonary vascular system: An anatomical and histochemical reinvestigation of the pulmonary venous return development in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肺循環の成り立ちと肺静脈形成の形態学的考察2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Radiation inducible MafB gene is required for thymic regeneration2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of masculinization: androgen signalling for external genitalia development2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epispadias and the associated embryopathies; genetic and developmental basis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Androgen Regulates Dimorphic F-Actin Assemblies in the Genital Organogenesis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental Contribution of Wnt-signal-responsive Cells to Mouse Reproductive Tract Formation2017

Author(s)

Journal Title

DOI

MURASHIMA AKI 村嶋亜紀

Murashima Aki 村嶋亜紀

[Journal Article] ウォルフ管上皮特異的β-catenin 遺伝子ノックアウトマウスの示す異所的尿管芽の病態解析2016

[Presentation] マウス胎仔における交感神経性パラガングリアの組織発生学的解析2024