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NISHIOKA TAKASHI  西岡 貴志

… Alternative Names

NISHIOKA Takashi  西岡 貴志

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Researcher Number 50641875
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1144-3881
Affiliation (Current) 2022: 東北大学, 歯学研究科, 講師
Affiliation (based on the past Project Information) *help 2022: 東北大学, 歯学研究科, 講師
2016 – 2021: 東北大学, 歯学研究科, 助教
2013 – 2016: 東北大学, 歯学研究科(研究院), 助教
2014: 東北大学, 大学院歯学研究科, 助教
Review Section/Research Field
Principal Investigator
Pathobiological dentistry/Dental radiology / Surgical dentistry / Basic Section 57080:Social dentistry-related
Except Principal Investigator
Social dentistry / Pathobiological dentistry/Dental radiology / Prosthodontics/ Dental materials science and / Periodontology / Basic Section 57080:Social dentistry-related / Basic Section 57030:Conservative dentistry-related / Studies on the Super-Aging Society
Keywords
Principal Investigator
ニコチン / 口腔がん / がん / 喫煙 / 細胞増殖 / NETs / 細菌感染 / 口腔細菌
Except Principal Investigator
うま味 / 味覚障害 … More / 高齢者 / タイ-日本 / ガン治療 / 慢性歯周炎 / 口腔粘膜バリア破綻 / 歯周病原細菌 / バリア破綻 / タイー日本 / IL-18 / シェーグレン症候群 / 唾液腺 / インフラマソーム / 唾液腺細胞 / 咀嚼 / メタボリックシンドローム / グライセミックインデックス / 咀嚼障害 / 食育 / 糖尿病 / Soft food / 咀嚼機能 / 口腔粘膜 / びらん・潰瘍病変 / 口腔扁平苔癬 / 抗原提示能 / オートファジー / 治療法 / 口腔粘膜疾患 / 剥離細胞診 / 組織細胞診 / 組織診断 / 細胞診断 / シアロルフィン / 社会心理ストレスモデル / 機械的アロデニア / シアロルフィンレセプター / Neprilysin / 慢性疼痛 / ストレス / 母子分離モデル / Porphyromonas gingivalis / Interleukin-31 / 歯肉上皮細胞 / 歯肉上皮バリア破綻 / マスト細胞 / 歯周病態・診断学 / タイ / 味覚ー唾液反射 / 酸味 / 口腔乾燥 / 唾液 / 味覚閾値 / ドライマウス / 口腔乾燥症 / 感受性低下 / 味覚受容体遺伝子 / Fusobacterium nucleatum / 好中球 / 好中球細胞外トラップ / 苦味受容体遺伝子 / 解毒酵素 / 遺伝子多型 / 発がんリスク / 医療ビッグデータ / 苦味受容体 / 一塩基多型解析 Less
  • Research Projects

    (13 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (34 People)
  •  「うま味」感受性低下の原因解明を基軸とした高齢者健康維持の治療基盤構築

    • Principal Investigator
      庄司 憲明
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Tohoku University
  •  NETsを起点とした口腔がん発生機序の解明~口腔細菌とニコチンのクロストーク~Principal Investigator

    • Principal Investigator
      西岡 貴志
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Tohoku University
  •  歯周病原細菌による好中球細胞外トラップ誘導を基軸とした歯肉上皮バリア破綻の解明

    • Principal Investigator
      多田 浩之
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Tohoku University
  •  苦味受容体と解毒酵素の多型解析と医療ビックデ-タによる発がんリスク評価法の開発

    • Principal Investigator
      庄司 憲明
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Studies on the Super-Aging Society
    • Research Institution
      Tohoku University
  •  Study on taste disorders and its treatment strategies: A comparative study between Japan and Thailand

    • Principal Investigator
      SHOJI NORIAKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Tohoku University
  •  Porphyromonas gingivalis induces the production of IL-31 by human mast cells, resulting in dysfunction of the gingival epithelial barrier

    • Principal Investigator
      Tada Hiroyuki
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Tohoku University
  •  New theory for chronic pain control by saliva-derived antinociceptive modulator.

    • Principal Investigator
      Shoji Noriaki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Social dentistry
    • Research Institution
      Tohoku University
  •  Elucidation of oral cancer cell proliferation mechanism by nicotine and enlightenment of smoking cessation based on scientific evidence.Principal Investigator

    • Principal Investigator
      Nishioka Takashi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
      Surgical dentistry
    • Research Institution
      Tohoku University
  •  Therapeutic innovation in oral mucosal leasions with erosion and ulcer by analyzing antigen presenting ability and autophagy

    • Principal Investigator
      Sugawara Yumiko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tohoku University
  •  Comparative study on taste sensitivity between Japan and Thailand

    • Principal Investigator
      Shoji Noriaki
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Tohoku University
  •  Analysis of the human salivary-gland apoptotic pass way for Sjogren's syndrome.

    • Principal Investigator
      MUROI AZUSA
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tohoku University
  •  Impairment of masticatory ability would induce the metabolic syndrome.

    • Principal Investigator
      TSUCHIYA Masahiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Tohoku University
  •  Elucidation of the molecular basis related to the nicotinic acetylcholine receptor involved in the development of oral cancerPrincipal Investigator

    • Principal Investigator
      NISHIOKA TAKASHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
      Surgical dentistry
    • Research Institution
      Tohoku University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

  • [Book] エンドトキシン・自然免疫研究22 エンドトキシン・自然免疫研究の新たな可能性を求めて2019

    • Author(s)
      多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
    • Total Pages
      82
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Book] エンドトキシン・自然免疫研究22 エンドトキシン・自然免疫研究の新たな可能性を求めて2019

    • Author(s)
      多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
    • Total Pages
      82
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-19K10143
  • [Book] エンドトキシン・自然免疫研究 212018

    • Author(s)
      多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
    • Total Pages
      4
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Journal Article] Relationship of MR imaging of submandibular glands to hyposalivation in Sj?gren's syndrome2019

    • Author(s)
      I Kojima, M Sakamoto, M Iikubo, Y Shimada, T Nishioka, T Sasano.
    • Journal Title

      Oral Diseases

      Volume: 25 Pages: 117-125

    • DOI

      10.1111/odi.12941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11287, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-18K09804
  • [Journal Article] Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor2019

    • Author(s)
      Nishioka T, Tada H, Ibaragi S, Chen CY, Sasano T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 509(2) Pages: 514-520

    • DOI

      10.1016/j.bbrc.2018.12.154

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-19K10143
  • [Journal Article] Porphyromonas gingivalis induces the production of interleukin-31 by human mast cells, resulting in dysfunction of the gingival epithelial barrier2019

    • Author(s)
      Tada Hiroyuki, Nishioka Takashi, Takase Aya, Numazaki Kento, Bando Kanan, Matsushita Kenji.
    • Journal Title

      Cellular Microbiology

      Volume: 21

    • DOI

      10.1111/cmi.12972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17240, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-19K10143, KAKENHI-PROJECT-16K11824
  • [Journal Article] Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma2019

    • Author(s)
      Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.
    • Journal Title

      Int J Oncol.

      Volume: 54(1) Pages: 283-294

    • DOI

      10.3892/ijo.2018.4631

    • NAID

      120006786204

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11669, KAKENHI-PROJECT-17K11836, KAKENHI-PROJECT-18K17224, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-17K11642, KAKENHI-PROJECT-16K20577
  • [Journal Article] Influence of voxel size and scan field of view on fracture-like artifacts from gutta-percha obturated endodontically treated teeth on cone-beam computed tomography images.2016

    • Author(s)
      Iikubo M, Nishioka T, Okura S, Kobayashi K, Sano T, Katsumata A, Ariji E, Kojima I, Sakamoto M, Sasano T.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol.

      Volume: 132(3) Pages: 187-191

    • DOI

      10.1016/j.jphs.2016.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Journal Article] Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells.2016

    • Author(s)
      Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita
    • Journal Title

      PLOS ONE

      Volume: 11(4)

    • DOI

      10.1371/journal.pone.0152794

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25463225, KAKENHI-PROJECT-26293438, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-26861586
  • [Journal Article] Direct delivery of a cytotoxic anticancer agent into the metastatic lymph node using nano/microbubbles and ultrasound2015

    • Author(s)
      Akira Kumasaka, Masahiro Iikubo, Takashi Nishioka, Ikuho Kojima, Noriaki Shoji, Maya Sakamoto, Takashi Sasano.
    • Journal Title

      Clinical Implant Dentistry and Related Research

      Volume: 印刷中 Pages: 1174-1179

    • DOI

      10.1111/cid.12227

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592949, KAKENHI-PROJECT-24659834, KAKENHI-PROJECT-25293382, KAKENHI-PROJECT-24792347, KAKENHI-PROJECT-25870047
  • [Journal Article] Nicotine increases the resistance of lung cancer to cisplatin through enhancing Bcl-2 stability2014

    • Author(s)
      Nishioka T, L-Y Luo, Shen L, He H, Mariyannis A, Dai W, Chen C.
    • Journal Title

      British Journal of Cancer

      Volume: 110(7) Pages: 1785-1792

    • DOI

      10.1038/bjc.2014.78

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25870047
  • [Journal Article] Physiological distal drift in rat molars contributes to acellular cementum formation.2013

    • Author(s)
      Tsuchiya S, Tsuchiya M, Nishioka T, Suzuki O, Sasano Y, Igarashi K.
    • Journal Title

      Anat Rec

      Volume: 296 Pages: 1255-1263

    • DOI

      10.1002/ar.22731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390439, KAKENHI-PROJECT-24390429, KAKENHI-PROJECT-25670813
  • [Presentation] Fusobacterium nucleatum感染によりマスト細胞が産生する細胞外トラップは、MIF依存的に炎症を誘導する2019

    • Author(s)
      多田浩之、西岡貴志、松下健二、菅原俊二
    • Organizer
      第61回歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Fusobacterium nucleatum感染によりマスト細胞が産生する細胞外トラップは、MIF依存的に炎症を誘導する2019

    • Author(s)
      多田浩之、西岡貴志、松下健二、菅原俊二
    • Organizer
      第61回歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-19K10143
  • [Presentation] Porphyromonas gingivalisによるマスト細胞由来interleukin-31を介した歯肉上皮細胞のclaudin-1ダウンレギュレーション作用2018

    • Author(s)
      多田浩之、西岡貴志、根本英二、松下健二
    • Organizer
      第149回日本歯科保存学会秋季学術大会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Porphyromonas gingivalisによるマスト細胞由来interleukin-31を介した歯肉上皮細胞のclaudin-1ダウンレギュレーション作用2018

    • Author(s)
      多田浩之, 西岡貴志, 根本英二, 松下健二
    • Organizer
      第149回日本歯科保存学会2018年度秋季学術大会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] 歯周病原細菌によるヒトマスト細胞からの細胞外トラップ産生と炎症誘導2018

    • Author(s)
      多田浩之、西岡貴志、松下健二
    • Organizer
      第24回日本エンドトキシン・自然免疫研究会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] P. gingivalis感染によりマスト細胞から産生されたIL-31はclaudin-1発現抑制を介して歯肉上皮バリア破綻を誘導する2018

    • Author(s)
      多田浩之、沼崎研人、西岡貴志、根本英二、松下健二、菅原俊二
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] パルスジェットを用いた新たな歯周炎治療法の開発~人工歯石の除去効果に関する検討~2018

    • Author(s)
      佐藤由加, 飯久保正弘, 西岡貴志, 中川敦寛
    • Organizer
      第149回日本歯科保存学会2018年度秋季学術大会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] P.gingivalis感染によりマスト細胞から産生されたIL-31はclaudin-1発現抑制を介して歯肉上皮バリア破綻を誘導する2018

    • Author(s)
      多田浩之, 沼崎研人, 沼崎研人, 西岡貴志, 松下健二, 菅原俊二
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] 歯周病原細菌によるヒトマスト細胞からの細胞外トラップ産生と炎症誘導2018

    • Author(s)
      多田浩之, 西岡貴志, 松下健二
    • Organizer
      第24回エンドトキシン・自然免疫研究会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] Fracture-like artifacts of gutta-percha cones on CBCT images influenced by the voxel size and FOV.2017

    • Author(s)
      Masahiro Iikubo, Takashi Nishioka, Kaoru Kobayashi, Takashi Sasano
    • Organizer
      International Congress of Dento-Maxillo-Facial Radiology
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] ニコチンはp44/42 MAPKシグナルを介して上皮細胞癌の増殖促進を誘導する2017

    • Author(s)
      西岡貴志、多田浩之
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] ニコチンはp44/p42 MAPKシグナルを介して上皮細胞癌の増殖促進を誘導する2017

    • Author(s)
      西岡貴志、多田浩之
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] 歯周病における neutrophil extracellular traps 産生と血管内皮細胞の炎症誘導2017

    • Author(s)
      多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
    • Organizer
      第23回日本エンドトキシン・自然免疫研究会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] Periodontal bacteria induce the production of MIF-associated neutrophil extracellular traps by human neutrophils2017

    • Author(s)
      Hiroyuki Tada, Takashi Nishioka
    • Organizer
      The 2017 Japan-NIH joint Symposium on Advances in Biomedical Research and Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Periodontal bacteria induce the production of MIF-associated neutrophil extracellular traps by human neutrophils2017

    • Author(s)
      Hiroyuki Tada, Takashi Nishioka
    • Organizer
      The 2017 Japan-NIH Joint Symposium
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2017-02-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Neutrophil extracellular trapsによるヒト血管内皮細胞のDel-1ダウンレギュレーション作用2017

    • Author(s)
      多田浩之、西岡貴志、松下健二、菅原俊二
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Neutrophil extracellular traps によるヒト血管内皮細胞の Del-1 産生抑制2017

    • Author(s)
      多田浩之、西岡貴志、松下健二、菅原俊二
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] 歯周病関連細菌による好中球の neutrophil extracellular traps 産生を介した炎 症反応の誘導2016

    • Author(s)
      多田 浩之、沼崎 研人、西岡 貴志、松下 健二、高田 春比古
    • Organizer
      第22回日本エンドトキシン・自然免疫研究会
    • Place of Presentation
      鹿児島
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] 歯周病関連細菌による好中球のneutrophil extracellular traps産生を介した炎症反応の誘導2016

    • Author(s)
      多田浩之、沼崎研人、西岡貴志、松下健二、高田春比古
    • Organizer
      第22回日本エンドトキシン・自然免疫研究会
    • Place of Presentation
      鹿児島県鹿児島市
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Fusobacterium nucleatumによるヒト好中球からのneutrophil extracellular traps誘導2016

    • Author(s)
      沼崎 研人、西岡 貴志、松下 健二、多田 浩之
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K20853
  • [Presentation] Fusobacterium nucleatumによるヒト好中球からのneutrophil extracellular traps誘導2016

    • Author(s)
      沼崎研人、西岡貴志、松下健二、多田浩之
    • Organizer
      第58回歯科基礎医学会学術大会・総会
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-16K11824
  • [Presentation] Nicotine exposure induces the proliferation of oral cancer cell2015

    • Author(s)
      Takashi Nishioka, Hiroyuki Tada
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-25870047
  • [Presentation] Sensitization of epithelial growth factor receptors by nicotine exposure may explore oral cancer2014

    • Author(s)
      Takashi Nishioka, Takashi Sasano
    • Organizer
      Innovative Research for Biosis-Abiosis Intelligent Interface Symposium
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25870047
  • [Presentation] CT画像にみられる根管充填剤による歯根破折様アーチファクトについて2013

    • Author(s)
      飯久保 正弘、西岡 貴志、小林 馨、有地 榮一郎、笹野 高嗣
    • Organizer
      第138回日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25870047
  • [Presentation] Nicotine Exposure Increases the Resistance of Cancer Cells to Cisplatin through Enhancing Bcl-2 Stability

    • Author(s)
      Takashi Nishioka, Ling-Yu Luo, Ling Shen, Huan He, Alexandros Mariyannis, Changyan Chen
    • Organizer
      Thirteenth Scientific Symposium of the Flight Attendant Medical Research Institute
    • Place of Presentation
      Miami, USA
    • Year and Date
      2014-05-05 – 2014-05-07
    • Data Source
      KAKENHI-PROJECT-25870047
  • [Presentation] Nicotine exposure increases the resistance of lung and breast cancer cells to cisplatin through enhancing Bcl-2 stability and promotes activation EGFR signal in oral cancer cells

    • Author(s)
      Takashi Nishioka, Ling-Yu Luo, Ling Shen, Huan He, Alexandros Mariyannis, Takashi Sasano, Changyan Chen
    • Organizer
      19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25870047
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