NISHIOKA TAKASHI 西岡貴志

… Alternative Names

Researcher Number	50641875
Other IDs	https://orcid.org/0000-0002-1144-3881
Affiliation (Current)	2020: 東北大学, 歯学研究科, 助教
Affiliation (based on the past Project Information) *help	2020: 東北大学, 歯学研究科(研究院), 助教 2016 – 2019: 東北大学, 歯学研究科, 助教 2013 – 2016: 東北大学, 歯学研究科(研究院), 助教 2014: 東北大学, 大学院歯学研究科, 助教
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Surgical dentistry / Basic Section 57080:Social dentistry-related Except Principal Investigator Social dentistry / Pathobiological dentistry/Dental radiology / Prosthodontics/ Dental materials science and / Periodontology / Basic Section 57030:Conservative dentistry-related / Studies on the Super-Aging Society
Keywords	Principal Investigator ニコチン / 口腔がん / がん / 喫煙 / 細胞増殖 Except Principal Investigator 味覚障害 / うま味 / 高齢者 / タイ-日本 / ガン治療 … More

NETsを起点とした口腔がん発生機序の解明～口腔細菌とニコチンのクロストーク～Principal InvestigatorOngoing
- Principal Investigator
  
  西岡貴志
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Tohoku University
歯周病原細菌による好中球細胞外トラップ誘導を基軸とした歯肉上皮バリア破綻の解明Ongoing
- Principal Investigator
  
  多田浩之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
苦味受容体と解毒酵素の多型解析と医療ビックデ－タによる発がんリスク評価法の開発Ongoing
- Principal Investigator
  
  庄司憲明
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Tohoku University
味覚障害の病因解明と治療戦略の構築　ー日本ータイ二国間比較研究ーOngoing
- Principal Investigator
  
  庄司憲明
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Social dentistry
- Research Institution
  Tohoku University
歯周病原細菌によるマスト細胞のIL-31を基軸とした歯肉上皮バリア破綻機序の解明Ongoing
- Principal Investigator
  
  多田浩之
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Tohoku University
New theory for chronic pain control by saliva-derived antinociceptive modulator.
- Principal Investigator
  
  Shoji Noriaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Social dentistry
- Research Institution
  Tohoku University
Elucidation of oral cancer cell proliferation mechanism by nicotine and enlightenment of smoking cessation based on scientific evidence.Principal Investigator
- Principal Investigator
  
  Nishioka Takashi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
  Surgical dentistry
- Research Institution
  Tohoku University
Therapeutic innovation in oral mucosal leasions with erosion and ulcer by analyzing antigen presenting ability and autophagy
- Principal Investigator
  
  Sugawara Yumiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tohoku University
Comparative study on taste sensitivity between Japan and Thailand
- Principal Investigator
  
  Shoji Noriaki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Social dentistry
- Research Institution
  Tohoku University
Analysis of the human salivary-gland apoptotic pass way for Sjogren's syndrome.
- Principal Investigator
  
  MUROI AZUSA
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tohoku University
Impairment of masticatory ability would induce the metabolic syndrome.
- Principal Investigator
  
  TSUCHIYA Masahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Tohoku University
Elucidation of the molecular basis related to the nicotinic acetylcholine receptor involved in the development of oral cancerPrincipal Investigator
- Principal Investigator
  
  NISHIOKA TAKASHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
  Surgical dentistry
- Research Institution
  Tohoku University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] エンドトキシン・自然免疫研究 212018
- Author(s)
  多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
- Total Pages
  4
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-15K20853
[Journal Article] Porphyromonas gingivalis induces the production of interleukin-31 by human mast cells, resulting in dysfunction of the gingival epithelial barrier2019
- Author(s)
  Tada H, Nishioka T, Takase A, Numazaki K, Bando K, Matsushita K.
- Journal Title
  
  Cellular Microbiology
  
  Volume: 21(3)
- DOI
  10.1111/cmi.12972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-18K17240, KAKENHI-PROJECT-15K20853
[Journal Article] Relationship of MR imaging of submandibular glands to hyposalivation in Sj?gren's syndrome2019
- Author(s)
  I Kojima, M Sakamoto, M Iikubo, Y Shimada, T Nishioka, T Sasano.
- Journal Title
  
  Oral Diseases
  
  Volume: 25 Pages: 117-125
- DOI
  10.1111/odi.12941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11287, KAKENHI-PROJECT-15K20853
[Journal Article] Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma2019
- Author(s)
  Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 54（1） Pages: 283-294
- DOI
  10.3892/ijo.2018.4631
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11669, KAKENHI-PROJECT-17K11836, KAKENHI-PROJECT-18K17224, KAKENHI-PROJECT-15K20853
[Journal Article] Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor2019
- Author(s)
  Nishioka T, Tada H, Ibaragi S, Chen CY, Sasano T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 509(2) Pages: 514-520
- DOI
  10.1016/j.bbrc.2018.12.154
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-15K20853
[Journal Article] Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells.2016
- Author(s)
  Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita
- Journal Title
  
  PLOS ONE
  
  Volume: 11(4)
- DOI
  10.1371/journal.pone.0152794
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25463225, KAKENHI-PROJECT-26293438, KAKENHI-PROJECT-15K20853, KAKENHI-PROJECT-26861586
[Journal Article] Influence of voxel size and scan field of view on fracture-like artifacts from gutta-percha obturated endodontically treated teeth on cone-beam computed tomography images.2016
- Author(s)
  Iikubo M, Nishioka T, Okura S, Kobayashi K, Sano T, Katsumata A, Ariji E, Kojima I, Sakamoto M, Sasano T.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol.
  
  Volume: 132（3） Pages: 187-191
- DOI
  10.1016/j.jphs.2016.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20853
[Journal Article] Insulin-Like Growth Factor I Inhibits Alveolar Bone Loss Following Tooth Extraction in Rats2015
- Author(s)
  Akira Kumasaka, Masahiro Iikubo, Takashi Nishioka, Ikuho Kojima, Noriaki Shoji, Maya Sakamoto, Takashi Sasano.
- Journal Title
  
  Clinical Implant Dentistry and Related Research
  
  Volume: 印刷中 Pages: 1174-1179
- DOI
  10.1111/cid.12227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592949, KAKENHI-PROJECT-24659834, KAKENHI-PROJECT-25293382, KAKENHI-PROJECT-24792347, KAKENHI-PROJECT-25870047
[Journal Article] Nicotine increases the resistance of lung cancer to cisplatin through enhancing Bcl-2 stability2014
- Author(s)
  Nishioka T, L-Y Luo, Shen L, He H, Mariyannis A, Dai W, Chen C.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 110(7) Pages: 1785-1792
- DOI
  10.1038/bjc.2014.78
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870047
[Journal Article] Physiological distal drift in rat molars contributes to acellular cementum formation.2013
- Author(s)
  Tsuchiya S, Tsuchiya M, Nishioka T, Suzuki O, Sasano Y, Igarashi K.
- Journal Title
  
  Anat Rec
  
  Volume: 296 Pages: 1255-1263
- DOI
  10.1002/ar.22731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390439, KAKENHI-PROJECT-24390429, KAKENHI-PROJECT-25670813
[Presentation] P.gingivalis感染によりマスト細胞から産生されたIL-31はclaudin-1発現抑制を介して歯肉上皮バリア破綻を誘導する2018
- Author(s)
  多田浩之, 沼崎研人, 沼崎研人, 西岡貴志, 松下健二, 菅原俊二
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] Porphyromonas gingivalisによるマスト細胞由来interleukin-31を介した歯肉上皮細胞のclaudin-1ダウンレギュレーション作用2018
- Author(s)
  多田浩之, 西岡貴志, 根本英二, 松下健二
- Organizer
  第149回日本歯科保存学会2018年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] P. gingivalis感染によりマスト細胞から産生されたIL-31はclaudin-1発現抑制を介して歯肉上皮バリア破綻を誘導する2018
- Author(s)
  多田浩之、沼崎研人、西岡貴志、根本英二、松下健二、菅原俊二
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] Porphyromonas gingivalisによるマスト細胞由来interleukin-31を介した歯肉上皮細胞のclaudin-1ダウンレギュレーション作用2018
- Author(s)
  多田浩之、西岡貴志、根本英二、松下健二
- Organizer
  第149回日本歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] パルスジェットを用いた新たな歯周炎治療法の開発~人工歯石の除去効果に関する検討~2018
- Author(s)
  佐藤由加, 飯久保正弘, 西岡貴志, 中川敦寛
- Organizer
  第149回日本歯科保存学会2018年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] 歯周病原細菌によるヒトマスト細胞からの細胞外トラップ産生と炎症誘導2018
- Author(s)
  多田浩之、西岡貴志、松下健二
- Organizer
  第24回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] 歯周病原細菌によるヒトマスト細胞からの細胞外トラップ産生と炎症誘導2018
- Author(s)
  多田浩之, 西岡貴志, 松下健二
- Organizer
  第24回エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] ニコチンはp44/42 MAPKシグナルを介して上皮細胞癌の増殖促進を誘導する2017
- Author(s)
  西岡貴志、多田浩之
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] Periodontal bacteria induce the production of MIF-associated neutrophil extracellular traps by human neutrophils2017
- Author(s)
  Hiroyuki Tada, Takashi Nishioka
- Organizer
  The 2017 Japan-NIH joint Symposium on Advances in Biomedical Research and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] ニコチンはp44/p42 MAPKシグナルを介して上皮細胞癌の増殖促進を誘導する2017
- Author(s)
  西岡貴志、多田浩之
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] Neutrophil extracellular traps によるヒト血管内皮細胞の Del-1 産生抑制2017
- Author(s)
  多田浩之、西岡貴志、松下健二、菅原俊二
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] 歯周病における neutrophil extracellular traps 産生と血管内皮細胞の炎症誘導2017
- Author(s)
  多田浩之、西岡貴志、松下健二、尾之上さくら、川原一芳
- Organizer
  第23回日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] Neutrophil extracellular trapsによるヒト血管内皮細胞のDel-1ダウンレギュレーション作用2017
- Author(s)
  多田浩之、西岡貴志、松下健二、菅原俊二
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] Fracture-like artifacts of gutta-percha cones on CBCT images influenced by the voxel size and FOV.2017
- Author(s)
  Masahiro Iikubo, Takashi Nishioka, Kaoru Kobayashi, Takashi Sasano
- Organizer
  International Congress of Dento-Maxillo-Facial Radiology
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] Periodontal bacteria induce the production of MIF-associated neutrophil extracellular traps by human neutrophils2017
- Author(s)
  Hiroyuki Tada, Takashi Nishioka
- Organizer
  The 2017 Japan-NIH Joint Symposium
- Place of Presentation
  宮城県仙台市
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] Fusobacterium nucleatumによるヒト好中球からのneutrophil extracellular traps誘導2016
- Author(s)
  沼崎研人、西岡貴志、松下健二、多田浩之
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] Fusobacterium nucleatumによるヒト好中球からのneutrophil extracellular traps誘導2016
- Author(s)
  沼崎研人、西岡貴志、松下健二、多田浩之
- Organizer
  第58回歯科基礎医学会学術大会・総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] 歯周病関連細菌による好中球の neutrophil extracellular traps 産生を介した炎症反応の誘導2016
- Author(s)
  多田浩之、沼崎研人、西岡貴志、松下健二、高田春比古
- Organizer
  第22回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K20853
[Presentation] 歯周病関連細菌による好中球のneutrophil extracellular traps産生を介した炎症反応の誘導2016
- Author(s)
  多田浩之、沼崎研人、西岡貴志、松下健二、高田春比古
- Organizer
  第22回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  鹿児島県鹿児島市
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K11824
[Presentation] Nicotine exposure induces the proliferation of oral cancer cell2015
- Author(s)
  Takashi Nishioka, Hiroyuki Tada
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25870047
[Presentation] Sensitization of epithelial growth factor receptors by nicotine exposure may explore oral cancer2014
- Author(s)
  Takashi Nishioka, Takashi Sasano
- Organizer
  Innovative Research for Biosis-Abiosis Intelligent Interface Symposium
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25870047
[Presentation] CT画像にみられる根管充填剤による歯根破折様アーチファクトについて2013
- Author(s)
  飯久保　正弘、西岡　貴志、小林　馨、有地　榮一郎、笹野　高嗣
- Organizer
  第138回日本歯科保存学会2013年度春季学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25870047
[Presentation] Nicotine exposure increases the resistance of lung and breast cancer cells to cisplatin through enhancing Bcl-2 stability and promotes activation EGFR signal in oral cancer cells
- Author(s)
  Takashi Nishioka, Ling-Yu Luo, Ling Shen, Huan He, Alexandros Mariyannis, Takashi Sasano, Changyan Chen
- Organizer
  19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine
- Place of Presentation
  Athens, Greece
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25870047
[Presentation] Nicotine Exposure Increases the Resistance of Cancer Cells to Cisplatin through Enhancing Bcl-2 Stability
- Author(s)
  Takashi Nishioka, Ling-Yu Luo, Ling Shen, Huan He, Alexandros Mariyannis, Changyan Chen
- Organizer
  Thirteenth Scientific Symposium of the Flight Attendant Medical Research Institute
- Place of Presentation
  Miami, USA
- Year and Date
  2014-05-05 – 2014-05-07
- Data Source
  KAKENHI-PROJECT-25870047

1. 笹野高嗣 (10125560)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. Shoji Noriaki (70250800)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 佐藤しづ子 (60225274)

# of Collaborated Projects: 3 results

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4. TSUCHIYA Masahiro (60372322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 上園保仁 (20213340)

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6. 駒井三千夫 (80143022)

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7. 菅原俊二 (10241639)

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8. 多田浩之 (70431632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
9. 松下健二 (90253898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. MUROI AZUSA (90463778)

# of Collaborated Projects: 1 results

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11. SASAKI Keiichi (30178644)

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12. KUROISHI Toshinobu (30400261)

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13. ENDO Yasuo (50005039)

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14. YAOITA Fukie (00382672)

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15. Sugawara Yumiko (30235866)

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16. 小嶋郁穂 (80447169)

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17. 伊藤あゆみ (50622990)

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18. 篠田雅路 (20362238)

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19. 古内壽 (50209160)

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20. 坪井明人 (00241646)

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21. KIYOURA Yusuke

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22. EGUCHI Takanori

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23. IBARAGI Soichiro

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24. 坂東加南

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25. 飯久保正弘

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26. 阪本真弥

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27. 小玉哲也

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28. 森士朗

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29. 島内英俊

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30. 松山孝司

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31. 萩原真

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32. 佐々木朗

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# of Collaborated Products: 1 results

NISHIOKA TAKASHI 西岡 貴志

NISHIOKA Takashi 西岡 貴志

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NETsを起点とした口腔がん発生機序の解明～口腔細菌とニコチンのクロストーク～Principal InvestigatorOngoing

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歯周病原細菌による好中球細胞外トラップ誘導を基軸とした歯肉上皮バリア破綻の解明Ongoing

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苦味受容体と解毒酵素の多型解析と医療ビックデ－タによる発がんリスク評価法の開発Ongoing

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味覚障害の病因解明と治療戦略の構築 ー日本ータイ二国間比較研究ーOngoing

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歯周病原細菌によるマスト細胞のIL-31を基軸とした歯肉上皮バリア破綻機序の解明Ongoing

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New theory for chronic pain control by saliva-derived antinociceptive modulator.

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Elucidation of oral cancer cell proliferation mechanism by nicotine and enlightenment of smoking cessation based on scientific evidence.Principal Investigator

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Therapeutic innovation in oral mucosal leasions with erosion and ulcer by analyzing antigen presenting ability and autophagy

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Comparative study on taste sensitivity between Japan and Thailand

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Analysis of the human salivary-gland apoptotic pass way for Sjogren's syndrome.

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Impairment of masticatory ability would induce the metabolic syndrome.

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Elucidation of the molecular basis related to the nicotinic acetylcholine receptor involved in the development of oral cancerPrincipal Investigator

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[Book] エンドトキシン・自然免疫研究 212018

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NISHIOKA TAKASHI 西岡貴志

NISHIOKA Takashi 西岡貴志

味覚障害の病因解明と治療戦略の構築　ー日本ータイ二国間比較研究ーOngoing