WATANABE Kousuke 渡邊広祐

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Watanabe Kousuke 渡邊広祐

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Researcher Number	50644291
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help	2023: 東京大学, 医学部附属病院, 特任准教授 2019 – 2022: 東京大学, 医学部附属病院, 講師 2013 – 2016: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Laboratory medicine / Tumor diagnostics
Keywords	Principal Investigator 肺がん / 非小細胞肺癌 / 個別化医療 / 細胞表面タンパク / 小細胞肺がん / 分子標的薬 / 薬剤感受性 / 原発性肺がん / 血小板 / EMT … More / RNA編集 / miRNA / バイオマーカー / 転写後制御 / 選択的ポリアデニル化 / マイクロRNA Less

小細胞肺がんのサブタイプと細胞表面たんぱく質に着目した個別化医療の実現Principal Investigator
- Principal Investigator
  
  渡邊広祐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Role of Platelets in Molecular Targeted Drug Resistance Mechanisms of Lung CancerPrincipal Investigator
- Principal Investigator
  
  Watanabe Kousuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
RNA editing in non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Watanabe Kousuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokyo
Alternative polyadenylation in lung cancerPrincipal Investigator
- Principal Investigator
  
  WATANABE Kousuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] NECTIN2 is a Prognostic Biomarker and Potential Therapeutic Target in Lung Adenocarcinoma2024
- Author(s)
  Takahiro Ando、Mirei Ka、Yuriko Sugiura、Masakatsu Tokunaga、Natsuki Nakagawa、Takahiro Iida、Yoko Matsumoto、Kousuke Watanabe、Masanori Kawakami、Masaaki Sato、Hidenori Kage
- Journal Title
  
  Respiratory Investigation (in press)
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08252
[Journal Article] Brief, manualised and semistructured individual psychotherapy programme for patients with advanced cancer in Japan: study protocol for Managing Cancer and Living Meaningfully (CALM) phase 2 trial2022
- Author(s)
  Seraki Miyamoto, Tadahiro Yamazaki, Ken Shimizu, Toshio Matsubara, Hidenori Kage, Kousuke Watanabe, Hiroshi Kobo, Yutaka Matsuyama, Gary Rodin, Kazuhiro Yoshiuchi
- Journal Title
  
  BMJ open
  
  Volume: 12 Issue: 3 Pages: e056136-e056136
- DOI
  10.1136/bmjopen-2021-056136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08622, KAKENHI-PROJECT-20K07920
[Journal Article] Integrin alpha 2 is associated with tumor progression and postoperative recurrence in non-small cell lung cancer2022
- Author(s)
  Matsumoto Yoko、Kage Hidenori、Morota Mizuki、Zokumasu Koichi、Ando Takahiro、Maemura Keita、Watanabe Kousuke、Kawakami Masanori、Hinata Munetoshi、Ushiku Tetsuo、Nakajima Jun、Nagase Takahide
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 53 Issue: 1 Pages: 63-73
- DOI
  10.1093/jjco/hyac148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07632, KAKENHI-PROJECT-22K08252, KAKENHI-PROJECT-19K08622
[Journal Article] Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency2021
- Author(s)
  Manaka Katsunori、Sato Junichiro、Takeuchi Maki、Watanabe Kousuke、Kage Hidenori、Kawai Taketo、Sato Yusuke、Miyagawa Takuya、Yamada Daisuke、Kume Haruki、Sato Shinichi、Nagase Takahide、Iiri Taroh、Nangaku Masaomi、Makita Noriko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11617-11617
- DOI
  10.1038/s41598-021-91032-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08996, KAKENHI-PROJECT-19K08622
[Journal Article] NRXN1 as a novel potential target of antibody-drug conjugates for small cell lung cancer2020
- Author(s)
  Takuma Yotsumoto, Keita Maemura, Kousuke Watanabe, Yosuke Amano, Yoko Matsumoto, Koichi Zokumasu, Takahiro Ando, Masanori Kawakami, Hidenori Kage, Jun Nakajima, Yutaka Yatomi, Takahide Nagase and Daiya Takai
- Journal Title
  
  Oncotarget
  
  Volume: 11 Issue: 39 Pages: 3590-3600
- DOI
  10.18632/oncotarget.27718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08622
[Journal Article] Dual EGFR and ABL Tyrosine Kinase Inhibitor Treatment in a Patient with Concomitant EGFR-Mutated Lung Adenocarcinoma and BCR-ABL1-Positive CML2020
- Author(s)
  Kousuke Watanabe, Hidenori Kage, Saki Nagoshi, Kazuhiro Toyama, Yoshiyuki Ohno, Aya Shinozaki-Ushiku, Kumi Nakazaki, Hiroshi Suzuki, Mineo Kurokawa, Takahide Nagase
- Journal Title
  
  Case Rep Oncol Med
  
  Volume: 2020 Pages: 1-6
- DOI
  10.1155/2020/4201727
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08622, KAKENHI-PROJECT-16H02653
[Journal Article] High expression of IRE1 in lung adenocarcinoma is associated with a lower rate of recurrence.2017
- Author(s)
  Sakatani T, Maemura K, Hiyama N, Amano Y, Watanabe K, Kage H, Fukayama M, Nakajima J, Yatomi Y, Nagase T, Takai D.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 17 Issue: 6 Pages: 1-8
- DOI
  10.1093/jjco/hyx031
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18440, KAKENHI-PROJECT-15K20917
[Journal Article] The chimeric transcript RUNX1-GLRX5: a biomarker for good postoperative prognosis in Stage IA non-small-cell lung cancer2016
- Author(s)
  Ishikawa R, Amano Y, Kawakami M, Sunohara M, Watanabe K, Kage H, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 46 Pages: 185-9
- DOI
  10.1093/jjco/hyv187
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20917
[Journal Article] Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM32015
- Author(s)
  Amano Y, Ishikawa R, Sakatani T, Ichinose J, Sunohara M, Watanabe K, Kage H, Nakajima J, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 13 Issue: 3 Pages: 457-60
- DOI
  10.1016/j.bbrc.2015.01.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830098, KAKENHI-PROJECT-23249045
[Journal Article] Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer2015
- Author(s)
  Kousuke Watanabe, Yosuke Amano, Rie Ishikawa, Mitsuhiro Sunohara, Hidenori Kage, Junji Ichinose, Atsushi Sano, Jun Nakajima, Masashi Fukayama, Yutaka Yatomi, Takahide Nagase, Nobuya Ohishi and Daiya Takai
- Journal Title
  
  Cancer Medicine
  
  Volume: 4 Issue: 10 Pages: 1573-82
- DOI
  10.1002/cam4.505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20917, KAKENHI-PROJECT-23249045
[Journal Article] Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer.2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 9 Pages: 1135-1141
- DOI
  10.1111/cas.12472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24791455, KAKENHI-PROJECT-25830098
[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes2013
- Author(s)
  Watanabe Kousuke, and Daiya Takai
- Journal Title
  
  Frontiers in genetics
  
  Volume: 4 Pages: 275-275
- DOI
  10.3389/fgene.2013.00275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830098
[Presentation] KIFC1 を標的とした過剰中心体収束阻害による小細胞肺癌に対する治療戦略の可能性2023
- Author(s)
  中川夏樹、徳永将勝、飯田崇博、何美鈴、安藤孝浩、前村啓太、渡邊広祐、鹿毛秀宣、川上正敬
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08252
[Presentation] 神経内分泌タイプの小細胞肺癌におけるコレシストキニン B 受容体の治療標的としての可能性2023
- Author(s)
  徳永将勝、中川夏樹、飯田崇博、何美玲、安藤孝浩、前村啓太、渡邊広祐、鹿毛秀宣、川上正敬
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08252
[Presentation] 非小細胞肺癌におけるインテグリン a5 の発現と機能の解析2023
- Author(s)
  何美玲、松本容子、安藤孝浩、シーチェン、飯田崇博、中川夏樹、徳永将勝、前村啓太、渡邊広祐、川上正敬、織田克利、鹿毛秀宣
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08252
[Presentation] High expression of endoplasmic reticulum oxidoreductin (ERO) 1L is associated with resistance to cisplatin2016
- Author(s)
  Toshio Sakatani, Keita Maemura, Noriko Hiyama, Yousuke Amano, Kousuke Watanabe, Hidenori Kage, Masashi Fukayama, Jun Nakajima, Yutaka Yatomi, Takahide Nagase, Daiya Takai
- Organizer
  Fourth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-01-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20917
[Presentation] Loss of PABPN1 and alternative polyadenylation yield poor prognosis in non-small cell lung cancer2014
- Author(s)
  Junji Ichinose, Kousuke Watanabe, Atsushi Sano, Takahide Nagase, Jun Nakajima, Masashi Fukayama, Yutaka Yatomi, Nobuya Ohishi, and Daiya Takai
- Organizer
  AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25830098
[Presentation] Histone methylation-mediated silencing of mir-139 enhances an aggressive phenotype of non-small cell lung cancer2014
- Author(s)
  Kousuke Watanabe, Mitsuhiro Sunohara, Yosuke Amano, Rie Ishikawa, Junji Ichinose, Jun Nakajima, Masashi Fukayama, Yutaka Yatomi, Takahide Nagase, Nobuya Ohishi, and Daiya Takai
- Organizer
  AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25830098

1. KAGE Hidenori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 槙田紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 佐藤潤一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 長瀬隆英

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# of Collaborated Products: 1 results
5. 天野陽介

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# of Collaborated Products: 1 results

WATANABE Kousuke 渡邊 広祐

Watanabe Kousuke 渡邊 広祐

Research Projects

Research Products

Co-Researchers

小細胞肺がんのサブタイプと細胞表面たんぱく質に着目した個別化医療の実現Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Platelets in Molecular Targeted Drug Resistance Mechanisms of Lung CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA editing in non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alternative polyadenylation in lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] NECTIN2 is a Prognostic Biomarker and Potential Therapeutic Target in Lung Adenocarcinoma2024

Author(s)

Journal Title

Data Source

[Journal Article] Brief, manualised and semistructured individual psychotherapy programme for patients with advanced cancer in Japan: study protocol for Managing Cancer and Living Meaningfully (CALM) phase 2 trial2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrin alpha 2 is associated with tumor progression and postoperative recurrence in non-small cell lung cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NRXN1 as a novel potential target of antibody-drug conjugates for small cell lung cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual EGFR and ABL Tyrosine Kinase Inhibitor Treatment in a Patient with Concomitant EGFR-Mutated Lung Adenocarcinoma and BCR-ABL1-Positive CML2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High expression of IRE1 in lung adenocarcinoma is associated with a lower rate of recurrence.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The chimeric transcript RUNX1-GLRX5: a biomarker for good postoperative prognosis in Stage IA non-small-cell lung cancer2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM32015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer.2014

Author(s)

WATANABE Kousuke 渡邊広祐

Watanabe Kousuke 渡邊広祐

[Presentation] KIFC1 を標的とした過剰中心体収束阻害による小細胞肺癌に対する治療戦略の可能性2023

[Presentation] 神経内分泌タイプの小細胞肺癌におけるコレシストキニン B 受容体の治療標的としての可能性2023