Hosokawa Ikuko 細川育子

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HOSOKAWA Ikuko 細川育子

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Researcher Number	50707908
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 徳島大学, 大学院医歯薬学研究部(歯学域), 講師 2018 – 2021: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(歯学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Conservative dentistry / Periodontology
Keywords	Principal Investigator 歯周炎 / ケモカイン / M１/M２マクロファージ / 抗炎症作用 / berteroin / ヒト歯根膜由来細胞 / 細胞外小胞 / ローズマリー / 接着分子 / Rosmarinic acid … More / サイトカイン / Carnosic acid / MMP / TNF-α / IL-27 / CXCL10 / MMP-1 / メラトニン / Ｔｈ１７細胞 / Ａｄｒｅｎｏｍｅｄｕｌｌｉｎ / Th17細胞 / 歯根膜細胞 / Ｔｈ１細胞 / 繊維芽細胞 / Adrenomedullin / Th1 … More Except Principal Investigator 歯周炎 / 歯学 / 抗炎症作用 / ポリフェノール / バイオフィルム / シグナル伝達 / 口腔上皮細胞 / 歯根膜由来細胞 / ハイドロキシアパタイト / 塩化セチルピリジニウム / フッ素 / 抗菌成分 / 齲蝕 / フッ化ジアンミン銀 / フッ化ジアミンシリケート / シグナル伝達経路 / サイトカイン / 6-MSITC / ワサビ / erucin / イソチオシアネート / キトサン / ナノカプセル / 柑橘類果皮含有生理活性物質 / Akt / MMP / 炎症性メディエーター / ヒト歯根膜由来細胞 / スダチチン / ノビレチン / 生理活性物質 / 柑橘類果皮 / 光触媒 / チタニアナノチューブ / 二酸化チタン / 免疫学 / 細胞・組織 / NF-κB / Alkannin / CCL5 / CCL3 / CCR5 / CXCL10 / IL-29 / STAT6 / CCL11 / 歯周組織構成細胞 / ケモカイン / 白血球 / う蝕 / 象牙質 / グルコン酸クロルヘキシジン / 酸蝕歯 / S. mutans / 抗菌性 / サホライド / 象牙質知覚過敏症 / 酸蝕症 Less

乳酸菌由来細胞外小胞を用いた歯周病治療戦略ーM1/M2マクロファージに着目してーPrincipal Investigator
- Principal Investigator
  
  細川育子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
ポリフェノール内包キトサンナノカプセルを用いた口腔バイオフィルム抑制技術の開発
- Principal Investigator
  
  尾崎和美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
ワサビ含有成分を歯周炎治療に用いるための基礎的研究～抗炎症作用に着目して～
- Principal Investigator
  
  細川義隆
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Study of the inhibitory effects of polyphenol loaded titania nanotubes on bacterial growth and biofilm formation
- Principal Investigator
  
  OZAKI Kazumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Basic study of the bioactive substances of a skin of citrus fruits for periodontal disease treatment
- Principal Investigator
  
  HOSOKAWA Yoshitaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Basic research for using spice-containing ingredients in the treatment of periodontitis-Focusing on rosemary-Principal Investigator
- Principal Investigator
  
  HOSOKAWA Ikuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Development of the method for prevention of root caries with antibacterial ammonium hexafluorosilicate
- Principal Investigator
  
  SUGE Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima
Analysis of leukocyte infiltration mechanism to participate in inflammatory bone resorption in periodontal lesion
- Principal Investigator
  
  HOSOKAWA Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
role of melatonin in periodontal diseasePrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Ikuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
The effect of adrenomedullin on Th17 cells in periodontal disease.Principal Investigator
- Principal Investigator
  
  HOSOKAWA Ikuko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
Development of the method for prevention of dental caries with antibacterial ammonium hexafluorosilicate
- Principal Investigator
  
  SUGE Toshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Cardamonin decreases inflammatory mediator expression in IL-1β-stimulated human periodontal ligament cells2024
- Author(s)
  Okamoto Risa、Hosokawa Yoshitaka、Hosokawa Ikuko、Ozaki Kazumi、Hosaka Keiichi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 51 Issue: 1
- DOI
  10.1007/s11033-023-09204-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09966, KAKENHI-PROJECT-22K09984
[Journal Article] Effects of erucin on inflammatory mediators and antioxidant enzymes’ expression in TNF-α-stimulated human oral epithelial cells2023
- Author(s)
  Shimoyama Masahiro、Hosokawa Yoshitaka、Hosokawa Ikuko、Ozaki Kazumi、Hosaka Keiichi
- Journal Title
  
  Immunopharmacology and Immunotoxicology
  
  Volume: 46 Issue: 1 Pages: 49-54
- DOI
  10.1080/08923973.2023.2250551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09966, KAKENHI-PROJECT-22K09967, KAKENHI-PROJECT-22K09984
[Journal Article] The effects of berteroin on inflammatory mediators and antioxidant enzymes expression in human periodontal ligament cells2023
- Author(s)
  Hosokawa Yoshitaka、Hosokawa Ikuko、Shimoyama Masahiro、Okamoto Risa、Ozaki Kazumi、Hosaka Keiichi
- Journal Title
  
  Naunyn-Schmiedeberg's Archives of Pharmacology
  
  Volume: 397 Issue: 4 Pages: 2233-2240
- DOI
  10.1007/s00210-023-02761-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09966, KAKENHI-PROJECT-22K09984
[Journal Article] 6-(Methylsulfinyl) Hexyl Isothiocyanate Inhibits IL-6 and CXCL10 Production in TNF-α-Stimulated Human Oral Epithelial Cells.2022
- Author(s)
  Masahiro Shimoyama, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki and Keiichi Hosaka
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 44 Issue: 7 Pages: 2915-2922
- DOI
  10.3390/cimb44070201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09966, KAKENHI-PROJECT-22K09967, KAKENHI-PROJECT-22K09984
[Journal Article] The Anti-Inflammatory Effects of Iberin on TNF-α-Stimulated Human Oral Epithelial Cells: In Vitro Research.2022
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Masahiro Shimoyama, Ayumi Fujii, Juri Sato, Kimitake Kadena, Kazumi Ozaki and Keiichi Hosaka
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 12 Pages: 3155-3155
- DOI
  10.3390/biomedicines10123155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09966, KAKENHI-PROJECT-22K09967, KAKENHI-PROJECT-22K09984
[Journal Article] The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1β-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells2021
- Author(s)
  Hosokawa Yoshitaka、Hosokawa Ikuko、Ozaki Kazumi、Matsuo Takashi
- Journal Title
  
  BioMed Research International
  
  Volume: 2021 Issue: 1 Pages: 1-6
- DOI
  10.1155/2021/8826586
- NAID
  120007147672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10151, KAKENHI-PROJECT-18K09600
[Journal Article] Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells.,2021
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2021 Pages: 1-7
- DOI
  10.1155/2021/5535844
- NAID
  120007185165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10132, KAKENHI-PROJECT-19K10151
[Journal Article] Nobiletin inhibits inflammatory reaction in interleukin-1β-stimulated human periodontal ligament cells.2021
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo.
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 5 Pages: 667-667
- DOI
  10.3390/pharmaceutics13050667
- NAID
  120007188425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10132, KAKENHI-PROJECT-19K10151
[Journal Article] 柑橘類果皮含有生理活性物質を歯周病治療に応用するための基礎的研究2021
- Author(s)
  細川育子、細川義隆
- Journal Title
  
  月刊メディカル・サイエンス・ダイジェスト
  
  Volume: 47 Pages: 36-37
- Data Source
  KAKENHI-PROJECT-19K10151
[Journal Article] 香辛料含有成分を歯周炎治療に用いるための基礎的研究2021
- Author(s)
  細川育子、細川義隆
- Journal Title
  
  アグリバイオ
  
  Volume: 5 Pages: 784-788
- NAID
  40022670021
- Data Source
  KAKENHI-PROJECT-19K10151
[Journal Article] 香辛料含有成分を歯周炎治療に用いるための基礎的研究2021
- Author(s)
  細川育子、細川義隆
- Journal Title
  
  地域ケアリング
  
  Volume: 23 Pages: 75-78
- NAID
  40022670021
- Data Source
  KAKENHI-PROJECT-19K10151
[Journal Article] Carnosic acid inhibits inflammatory cytokines production in human periodontal ligament cells.2020
- Author(s)
  Hosokawa I., Hosokawa Y., Ozaki K., Matsuo T.
- Journal Title
  
  Immunopharmacology and Immunotoxicology
  
  Volume: 42 Issue: 4 Pages: 373-378
- DOI
  10.1080/08923973.2020.1782427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10132, KAKENHI-PROJECT-19K10151, KAKENHI-PROJECT-18K09600
[Journal Article] Investigation of the Mechanism of Leucocyte Infiltration in Periodontal Lesion and Search of Curative Agent of Periodontal Disease2019
- Author(s)
  細川義隆
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 62 Issue: 6 Pages: 260-262
- DOI
  10.11471/shikahozon.62.260
- NAID
  130007783254
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-19K10151
[Journal Article] Carnosic Acid Inhibits CXCR3 Ligands Production in IL-27-Stimulated Human Oral Epithelial Cells2019
- Author(s)
  Hosokawa Ikuko、Hosokawa Yoshitaka、Ozaki Kazumi、Matsuo Takashi
- Journal Title
  
  Inflammation
  
  Volume: 印刷中 Issue: 4 Pages: 1311-1316
- DOI
  10.1007/s10753-019-00991-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-18K09600, KAKENHI-PROJECT-19K10132, KAKENHI-PROJECT-19K10151
[Journal Article] Sudachitin Inhibits Matrix Metalloproteinase-1 and -3 Production in Tumor Necrosis Factor-α-Stimulated Human Periodontal Ligament Cells.2019
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Inflammation
  
  Volume: 42 Issue: 4 Pages: 1456-1462
- DOI
  10.1007/s10753-019-01007-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09600, KAKENHI-PROJECT-19K10132, KAKENHI-PROJECT-19K10151
[Journal Article] Transforming growth factor-β1 increases C-C chemokine ligand 11 production in interleukin 4-stimulated human periodontal ligament cells.2018
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Cell Biology International
  
  Volume: 42 Issue: 10 Pages: 1395-1400
- DOI
  10.1002/cbin.11030
- NAID
  120006706300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09600, KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834
[Journal Article] Interleukin (IL)-35 Suppresses IL-6 and IL-8 Production in IL-17A-Stimulated Human Periodontal Ligament Cells.2018
- Author(s)
  Shindo S, Hosokawa Y, Hosokawa I, Shiba H.
- Journal Title
  
  Inflammation
  
  Volume: - Issue: 3 Pages: 1-6
- DOI
  10.1007/s10753-018-0938-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06896, KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-18K09600, KAKENHI-PROJECT-19K19028
[Journal Article] Effects of Theaflavin on Chemokine Production in TNF-α-stimulated Oral Epithelial Cells2018
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 61 Issue: 1 Pages: 10-16
- DOI
  10.11471/shikahozon.61.10
- NAID
  130006406446
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-16K11554
[Journal Article] Honokiol and Magnolol Inhibit CXCL10 and CXCL11 Production in IL-27-Stimulated Human Oral Epithelial Cells.2018
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Inflammation
  
  Volume: 41 Issue: 6 Pages: 2110-2115
- DOI
  10.1007/s10753-018-0854-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09600, KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834
[Journal Article] IL-29 Enhances CXCL10 Production in TNF-α-stimulated Human Oral Epithelial Cells.2017
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ozaki K, Matsuo T.
- Journal Title
  
  Immunological investigations
  
  Volume: 46 Issue: 6 Pages: 615-624
- DOI
  10.1080/08820139.2017.1336176
- NAID
  120006543832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-17H06896, KAKENHI-PROJECT-15K11392
[Journal Article] IL-27 Modulates Chemokine Production in TNF-α -Stimulated Human Oral Epithelial Cells.2017
- Author(s)
  Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 43 Issue: 3 Pages: 1198-1206
- DOI
  10.1159/000481760
- NAID
  120006550809
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-15K11392
[Journal Article] Shikonin Inhibits Inflammatory Cytokine Production in Human Periodontal Ligament Cells2016
- Author(s)
  Shindo S, Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T
- Journal Title
  
  Inflammation
  
  Volume: 39 Pages: 1124-1129
- DOI
  10.1007/s10753-016-0344-0
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J03452, KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-16K11834
[Journal Article] Gomisin N Decreases Inflammatory Cytokine Production in Human Periodontal Ligament Cells2016
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ozaki K, Matsuo T
- Journal Title
  
  Inflammation
  
  Volume: 40 Issue: 2 Pages: 360-365
- DOI
  10.1007/s10753-016-0482-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J03452, KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-16K11834, KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-17H06896
[Journal Article] Metatonin Inhibits CXCL10 and MMP-1 Production in IL-1β-stimulated Human Periodontal Ligament Cells2016
- Author(s)
  Ikuko Hosokawa, Yoshitaka Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Inflammation
  
  Volume: 39 Issue: 4 Pages: 1520-1526
- DOI
  10.1007/s10753-016-0386-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834
[Journal Article] IL-4 modulates CCL11 and CCL20 productions from IL-1β-stimulated human periodontal ligament cells2016
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 38 Issue: 1 Pages: 153-159
- DOI
  10.1159/000438617
- NAID
  120006550808
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219
[Journal Article] Alkannin inhibits CCL3 and CCL5 production in human periodontal ligament cells2016
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ohta Y, Ozaki K, Matsuo T
- Journal Title
  
  Cell Biology International
  
  Volume: 40 Issue: 12 Pages: 1380-1385
- DOI
  10.1002/cbin.10692
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J03452, KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-16K11554, KAKENHI-PROJECT-16K11834
[Journal Article] Calcitriol supressed inflammatory reactions in IL-1β-stimulated human periodontal ligament cells2015
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
- Journal Title
  
  Inflammation
  
  Volume: 38 Issue: 6 Pages: 2252-2258
- DOI
  10.1007/s10753-015-0209-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K11392, KAKENHI-PROJECT-15J03452, KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219
[Journal Article] IL-6 trans-signaling enhances CCL20 production from IL-1・-stimulated human periodontal ligament cells2014
- Author(s)
  Hosokawa Y, Shindo S, Hosokawa I, Ozaki K, Matsuo T
- Journal Title
  
  Inflammation
  
  Volume: 37(2) Issue: 2 Pages: 381-386
- DOI
  10.1007/s10753-013-9750-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219, KAKENHI-PROJECT-25893158
[Journal Article] IL-22 Enhances CCL20 Production in IL-1β-Stimulated Human Gingival Fibroblasts.2014
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ozaki K, Matsuo T.
- Journal Title
  
  Inflammation
  
  Volume: 37 Issue: 6 Pages: 2062-2066
- DOI
  10.1007/s10753-014-9939-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219, KAKENHI-PROJECT-25893158
[Journal Article] Genipin inhibits IL-1・-induced CCL20 and IL-6 production from human periodontal ligament cells2014
- Author(s)
  Shindo S, Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 33 Issue: 2 Pages: 357-364
- DOI
  10.1159/000356675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219, KAKENHI-PROJECT-25893158
[Journal Article] (-)-Epigallocatechin-3-gallate inhibits CC chemokine ligand 11 production in human gingival fibroblasts2013
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ozaki K, Matsuo T
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 31 Issue: 6 Pages: 960-967
- DOI
  10.1159/000350114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219, KAKENHI-PROJECT-25893158
[Journal Article] TLR3 agonist enhances CC chemokine ligand 20 production in IL-1β-stimulated human gingival fibroblasts.2013
- Author(s)
  Hosokawa Y, Hosokawa I, Shindo S, Ozaki K, Matsuo T.
- Journal Title
  
  Cellular Immunology
  
  Volume: 283 Issue: 1-2 Pages: 8-11
- DOI
  10.1016/j.cellimm.2013.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462962, KAKENHI-PROJECT-25463219, KAKENHI-PROJECT-25893158
[Presentation] Sudachitinがヒト歯髄細胞の炎症メディエーター発現に与える影響2023
- Author(s)
  三枝克啓, 中西正, 蔵本瞳, 細川義隆, 細川育子, 武川大輔, 保坂啓一
- Organizer
  日本歯科保存学会 2023年度春季学術大会(第158回)
- Data Source
  KAKENHI-PROJECT-22K09966
[Presentation] TNF-αで刺激されたヒト歯根膜由来細胞の炎症性メディエーター発現に与えるcardamoninの影響2023
- Author(s)
  岡本梨沙, 細川義隆, 細川育子, 下山真弘, 尾崎和美, 保坂啓一
- Organizer
  日本歯科保存学会2023年度秋季学術大会(第159回)
- Data Source
  KAKENHI-PROJECT-22K09984
[Presentation] TNF-αで刺激されたヒト歯根膜由来細胞の炎症性メディエーター発現に与えるcardamoninの影響2023
- Author(s)
  岡本梨沙, 細川義隆, 細川育子, 下山真弘, 尾崎和美, 保坂啓一
- Organizer
  日本歯科保存学会2023年度秋季学術大会(第159回)
- Data Source
  KAKENHI-PROJECT-22K09966
[Presentation] TNF-αで刺激されたヒト口腔上皮細胞の炎症性メディエーター産生ならびに抗酸化タンパク質発現に対するErucinの影響2023
- Author(s)
  下山真弘, 細川義隆, 細川育子, 保坂啓一
- Organizer
  日本歯科保存学会 2023年度春季学術大会(第158回)
- Data Source
  KAKENHI-PROJECT-22K09984
[Presentation] TNF-αで刺激されたヒト歯根膜由来細胞の炎症性メディエーター発現に対するcardamoninの影響2023
- Author(s)
  岡本梨沙，細川義隆, 細川育子, 下山真弘，尾崎和美，保坂啓一
- Organizer
  第159回日本歯科保存学会2023年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-22K09967
[Presentation] TNF-αで刺激されたヒト口腔上皮細胞の炎症性メディエーター産生ならびに抗酸化タンパク質発現に対するErucinの影響2023
- Author(s)
  下山真弘, 細川義隆, 細川育子, 保坂啓一
- Organizer
  日本歯科保存学会 2023年度春季学術大会(第158回)
- Data Source
  KAKENHI-PROJECT-22K09966
[Presentation] Sudachitinがヒト歯髄細胞の炎症メディエーター発現に与える影響2023
- Author(s)
  三枝克啓, 中西正, 蔵本瞳, 細川義隆, 細川育子, 武川大輔, 保坂啓一
- Organizer
  日本歯科保存学会 2023年度春季学術大会(第158回)
- Data Source
  KAKENHI-PROJECT-22K09984
[Presentation] 6-MSITCはTNF-αが誘導するヒト口腔上皮由来細胞のIL-6およびCXCL10産生を抑制する2022
- Author(s)
  下山真弘, 細川義隆, 細川育子, 保坂啓一
- Organizer
  日本歯科保存学会 2022年度春季学術大会
- Data Source
  KAKENHI-PROJECT-22K09984
[Presentation] 6-MSITCはTNF-αが誘導するヒト口腔上皮由来細胞のIL-6およびCXCL10産生を抑制する2022
- Author(s)
  下山真弘, 細川義隆, 細川育子, 保坂啓一
- Organizer
  第156回春季日本歯科保存学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09966
[Presentation] イベリンがヒト口腔上皮細胞の炎症性メディエーター産生に及ぼす影響の解析2022
- Author(s)
  藤井亜祐美, 嘉手納公威, 佐藤朱里, 下山真弘, 細川育子, 細川義隆
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09966
[Presentation] イベリンがヒト口腔上皮細胞の炎症性メディエーター産生に及ぼす影響の解析2022
- Author(s)
  藤井亜祐美, 嘉手納公威, 佐藤朱里, 下山真弘, 細川育子, 細川義隆
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09984
[Presentation] Nobiletinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する2021
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  2021年度日本歯科保存学会春季学術大会(第154回)
- Data Source
  KAKENHI-PROJECT-19K10151
[Presentation] Nobiletinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する2021
- Author(s)
  細川義隆, 細川育子, 尾崎和美
- Organizer
  日本歯科保存学会2021年度春季学術大会(第154回)
- Data Source
  KAKENHI-PROJECT-19K10132
[Presentation] Sudachitinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する2020
- Author(s)
  細川義隆、細川育子、尾崎和美
- Organizer
  2020年度日本歯科保存学会春季学術大会（第152回）
- Data Source
  KAKENHI-PROJECT-19K10151
[Presentation] Sudachitinはヒト歯根膜由来細胞のIL-1β誘導炎症性メディエーター産生を抑制する2020
- Author(s)
  細川　義隆、細川　育子、尾崎　和美
- Organizer
  第152回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-18K09600
[Presentation] Carnosic Acid はヒト歯根膜由来細胞のIL-1β誘導炎症性サイトカイン産生を抑制する2020
- Author(s)
  細川　育子、細川　義隆、尾崎　和美
- Organizer
  第152回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-18K09600
[Presentation] Carnosic Acidはヒト歯根膜由来細胞のIL-1β誘導炎症性サイトカイン産生を抑制する2020
- Author(s)
  細川育子、細川義隆、尾崎和美
- Organizer
  2020年度日本歯科保存学会春季学術大会（第152回）
- Data Source
  KAKENHI-PROJECT-19K10151
[Presentation] IL-27はヒト口腔上皮細胞のCXCR3リガンドを産生する2018
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09600
[Presentation] Carnosic acidはヒト口腔上皮細胞のIL-27誘導CXCR3リガンド産生を抑制する2018
- Author(s)
  細川育子、細川義隆、尾崎和美、松尾敬志
- Organizer
  第１４９回日本歯科保存学会２０１８年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] Carnosic acidはヒト口腔上皮細胞のIL-27誘導CXCR3リガンド産生を抑制する2018
- Author(s)
  細川育子、細川義隆、尾崎和美、松尾敬志
- Organizer
  第149回秋季日本歯科保存学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09600
[Presentation] Il-27はヒト口腔上皮細胞のCXCR3リガンド産生を誘導する2018
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第６１回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] IL-29はヒト口腔上皮細胞のCXCL10産生を増強する2017
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第147回日本歯科保存学会2017年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] IL-29はヒト口腔上皮細胞のCXCL10産生を増強する2017
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第147回日本歯科保存学会2017年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] IL-29はTNF-αが誘導するヒト口腔上皮細胞のCXCL10産生を増強する2017
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] IL-29はTNF-αが誘導するヒト口腔上皮細胞のCXCL10産生を増強する2017
- Author(s)
  細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] Gomisin Nはヒト歯根膜由来細胞の炎症性サイトカイン産生を抑制する2016
- Author(s)
  細川義隆、細川育子、進藤智、尾崎和美、松尾敬志
- Organizer
  日本歯科保存学会2016年度秋季保存学会
- Place of Presentation
  キッセイ文化ホール（長野県・松本市）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] Gomisin Nはヒト歯根膜由来細胞の炎症性サイトカイン産生を抑制する2016
- Author(s)
  細川義隆、細川育子、進藤智、尾崎和美、松尾敬志
- Organizer
  日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  キッセイ文化ホール（長野県・松本市）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] シトルリン化ビメンチンは破骨細胞分化を促進する2016
- Author(s)
  進藤智、池田淳史、細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  キッセイ文化ホール（長野県・松本市）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K11834
[Presentation] シトルリン化ビメンチンは破骨細胞分化を促進する2016
- Author(s)
  進藤智、池田淳史、細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  日本歯科保存学会2016年度秋季保存学会
- Place of Presentation
  キッセイ文化ホール（長野県・松本市））
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] Alkanninはヒト歯根膜由来細胞のCCR5 ligand産生を抑制する2015
- Author(s)
  細川　義隆、細川　育子、進藤　智、尾崎　和美、松尾　敬志
- Organizer
  第１４３回秋季歯科保存学会学術大会
- Place of Presentation
  文京シビックホール（東京都文京区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] IL-4がヒト歯根膜由来細胞のCCL11およびCCL20産生に及ぼす影響2015
- Author(s)
  細川　義隆、細川　育子、進藤　智、尾崎　和美、松尾　敬志
- Organizer
  第５８回秋季日本歯周病学会学術大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K11392
[Presentation] IL-4 modulates chemokine productions from IL-1β-stimulated human periodontal ligament cells.2015
- Author(s)
  Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
- Organizer
  93rd General Session & Exhibition of the IADR
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Year and Date
  2015-03-12
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] Melatonin inhibits inflammatory mediators productions in human periodontal ligament cells.2015
- Author(s)
  Ikuko Hosokawa, Yoshitaka Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
- Organizer
  93rd General Session & Exhibition of the IADR
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Year and Date
  2015-03-12
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] The effect of genipin on dendritic cells activation.2015
- Author(s)
  Satoru Shindo, Ikuko Hosokawa, Yoshitaka Hosokawa, Kazumi Ozaki, Takashi Matsuo
- Organizer
  93rd General Session & Exhibition of the IADR
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Year and Date
  2015-03-13
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] 活性型ビタミンＤはIL-1β刺激ヒト歯根膜細胞の炎症性サイトカイン産生を抑制する2014
- Author(s)
  細川義隆、細川育子、進藤智、尾崎和美、松尾敬志
- Organizer
  第140回日本歯科保存学会春季学術大会
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール、滋賀県大津市
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] genipinはE.coli LPSが誘導するヒト歯根膜細胞のIL-6およびIL-8産生を抑制する2014
- Author(s)
  進藤智、細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第140回日本歯科保存学会春季学術大会
- Place of Presentation
  滋賀県立芸術劇場びわ湖ホール、滋賀県大津市
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] shikoninがヒト歯根膜由来細胞のIL-6およびIL-8産生に与える影響2014
- Author(s)
  進藤智、細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第141回日本歯科保存学会秋季学術大会
- Place of Presentation
  山形テルサ、山形県山形市
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] genipinはTNF-αが誘導するヒト歯根膜細胞のIL-6産生を抑制する2014
- Author(s)
  北中祐太郎、細川義隆、細川育子、進藤智、尾崎和美、松尾敬志
- Organizer
  第57回春季日本歯周病学会学術大会
- Place of Presentation
  岐阜県長良川国際会議場、岐阜県岐阜市
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] GenipinはIL-1betaが誘導するヒト歯根膜細胞のCCL20およびIL-6産生を抑制する
- Author(s)
  進藤智、細川義隆、細川育子、尾崎和美、松尾敬志
- Organizer
  第139回秋季日本歯科保存学会学術大会
- Place of Presentation
  秋田県総合生活文化会館（秋田県）
- Data Source
  KAKENHI-PROJECT-25893158
[Presentation] The effect of genipin on MMP-1 and MMP-3 expression in IL-1beta-stimulated human periodontal ligament cells
- Author(s)
  Satoru Shindo, Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki, Takashi Matsuo
- Organizer
  The 13th Joint Scientific Meeting of JSCD-KACD
- Place of Presentation
  The K-hotel & Resort　（韓国）
- Data Source
  KAKENHI-PROJECT-25893158

1. HOSOKAWA Yoshitaka (90346601)

# of Collaborated Projects: 8 results

# of Collaborated Products: 54 results
2. 中西正 (00217770)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
3. SUGE Toshiyuki (60243713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIKAWA Kunio (90202952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OZAKI Kazumi (90214121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. 湯本浩通 (60284303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAHASHI Kanako (80403715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松尾敬志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 進藤智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hosokawa Ikuko 細川 育子

HOSOKAWA Ikuko 細川 育子

Research Projects

Research Products

Co-Researchers

乳酸菌由来細胞外小胞を用いた歯周病治療戦略ーM1/M2マクロファージに着目してーPrincipal Investigator

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ポリフェノール内包キトサンナノカプセルを用いた口腔バイオフィルム抑制技術の開発

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ワサビ含有成分を歯周炎治療に用いるための基礎的研究～抗炎症作用に着目して～

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Study of the inhibitory effects of polyphenol loaded titania nanotubes on bacterial growth and biofilm formation

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Basic study of the bioactive substances of a skin of citrus fruits for periodontal disease treatment

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Basic research for using spice-containing ingredients in the treatment of periodontitis-Focusing on rosemary-Principal Investigator

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Development of the method for prevention of root caries with antibacterial ammonium hexafluorosilicate

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Analysis of leukocyte infiltration mechanism to participate in inflammatory bone resorption in periodontal lesion

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role of melatonin in periodontal diseasePrincipal Investigator

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The effect of adrenomedullin on Th17 cells in periodontal disease.Principal Investigator

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Development of the method for prevention of dental caries with antibacterial ammonium hexafluorosilicate

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[Journal Article] Cardamonin decreases inflammatory mediator expression in IL-1β-stimulated human periodontal ligament cells2024

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[Journal Article] Effects of erucin on inflammatory mediators and antioxidant enzymes’ expression in TNF-α-stimulated human oral epithelial cells2023

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DOI

Hosokawa Ikuko 細川育子

HOSOKAWA Ikuko 細川育子