Shiba Aya 柴綾

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Shib Aya 柴綾

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Researcher Number	50708427
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 筑波大学, 医学医療系, 准教授 2017 – 2019: 筑波大学, 医学医療系, 助教 2014 – 2015: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Human pathology / Transformative Research Areas, Section (IV) / Basic Section 49020:Human pathology-related Except Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 肺腺癌 / 初期悪性化 / OCIAD2 / ミトコンドリア / アポトーシス / リサイクリング / チロシンキナーゼ / USP8 / SFN / 受容体型チロシンキナーゼ … More / 脱ユビキチン化 / トランスジェニックマウス / リン酸化cyclin E1 / stratifin / SKP1 / Stratifin … More Except Principal Investigator KRAS / 胃腸上皮型 / 肺腺癌 / 肺癌 / 胃腸上皮分化 / HNF4A / Non-TRU / neuroendocrine tumor / lung adenocarcinoma / non-TRU type / TTF-1 / HNF4α Less

宇宙及び地上実験検体の空間マルチオミックス測定プラットフォームの整備Principal Investigator
- Principal Investigator
  
  柴綾
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  University of Tsukuba
Elucidation of mechanisms of carcinogenesis, metastasis, and metabolism based on histological characteristics of HNF4alpha-positive lung adenocarcinoma
- Principal Investigator
  
  松原大祐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba
Functional analysis of OCIAD2 localized at mitochondria in lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Shib Aya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba
Molecular mechanism for stabilization of RTKs proteins by SFN in lung adenocarcinoma.Principal Investigator
- Principal Investigator
  
  Shiba Aya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  University of Tsukuba
Analysis for molecular mechanism of SFN-induced lung adenocarcinoma progressionPrincipal Investigator
- Principal Investigator
  
  Shiba Aya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  University of Tsukuba

All 2018 2017 2015 2014

All Journal Article Presentation

[Journal Article] Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma2018
- Author(s)
  Kim Yunjung、Shiba-Ishii Aya、Nakagawa Tomoki、Iemura Shun-ichiro、Natsume Tohru、Nakano Noriyuki、Matsuoka Ryota、Sakashita Shingo、Lee SangJoon、Kawaguchi Atsushi、Sato Yukio、Noguchi Masayuki
- Journal Title
  
  Oncogene
  
  Volume: 37 Issue: 40 Pages: 5387-5402
- DOI
  10.1038/s41388-018-0342-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05192, KAKENHI-PROJECT-17K15634
[Journal Article] Stratifin accelerates progression of lung adenocarcinoma at an early stage.2015
- Author(s)
  Shiba-Ishii A, Kim Y, Shiozawa T, Iyama S, Satomi K, Kano J, Sakashita S, Morishita Y, Noguchi M.
- Journal Title
  
  Molecular Cancer
  
  Volume: 14 Issue: 1 Pages: 142-142
- DOI
  10.1186/s12943-015-0414-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860230, KAKENHI-PROJECT-25293086
[Journal Article] Moesin overexpression is a unique biomarker of adenomyosis.2014
- Author(s)
  Ohara R, Michikami H, Nakamura Y, Sakata A, Sakashita S, Satomi K, Shiba-Ishii A, Kano J, Yoshikawa H, Noguchi M.
- Journal Title
  
  Pathol Int.
  
  Volume: 64 Issue: 3 Pages: 115-122
- DOI
  10.1111/pin.12148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670693, KAKENHI-PROJECT-26860230
[Journal Article] Immunocytochemical staining for stratifin and OCIAD2 in bronchial washing specimens increases sensitivity for diagnosis of lung cancer.2014
- Author(s)
  Itoguchi N1, Nakagawa T, Murata Y, Li D, Shiba-Ishii A, Minami Y, Noguchi M.
- Journal Title
  
  Cytopathology.
  
  Volume: - Issue: 6 Pages: 354-361
- DOI
  10.1111/cyt.12220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293086, KAKENHI-PROJECT-26670172, KAKENHI-PROJECT-26860230
[Presentation] Stratifin interaction with USP8 is regulated by PP1 and AKT for stabilization of EGFR in lung adenocarcinoma.2018
- Author(s)
  Kim Yunjung、柴綾、野口雅之
- Organizer
  6th JCA-AACR joint meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15634
[Presentation] Stratifin regulates stabilization of receptor tyrosine kinases via activation of ubiquitin-specific protease 8 in lung adenocarcinoma2017
- Author(s)
  Aya Shiba, YunJung Kim, and Masayuki Noguchi
- Organizer
  18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15634
[Presentation] Stratifin accelerates progression of lung adenocarcinoma at an early stage2015
- Author(s)
  Aya Shiba-Ishii, Yunjung Kim, Toshihiro Shiozawa, Shinji Iyama, Yukio Morishita, and Masayuki Noguchi
- Organizer
  World Conference on Lung Cancer
- Place of Presentation
  Denver Convention Center (USA)
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860230

1. 野口雅之 (00198582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 松原大祐 (80415554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 武田憲彦 (40422307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 伊東剛 (20733075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村上善則 (30182108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kim Yunjung

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. NATSUME Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. KAWAGUCHI Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 吉川裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiba Aya 柴 綾

Shib Aya 柴 綾

Research Projects

Research Products

Co-Researchers

宇宙及び地上実験検体の空間マルチオミックス測定プラットフォームの整備Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms of carcinogenesis, metastasis, and metabolism based on histological characteristics of HNF4alpha-positive lung adenocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of OCIAD2 localized at mitochondria in lung adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism for stabilization of RTKs proteins by SFN in lung adenocarcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis for molecular mechanism of SFN-induced lung adenocarcinoma progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stratifin accelerates progression of lung adenocarcinoma at an early stage.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Moesin overexpression is a unique biomarker of adenomyosis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunocytochemical staining for stratifin and OCIAD2 in bronchial washing specimens increases sensitivity for diagnosis of lung cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Stratifin interaction with USP8 is regulated by PP1 and AKT for stabilization of EGFR in lung adenocarcinoma.2018

Author(s)

Organizer

Data Source

[Presentation] Stratifin regulates stabilization of receptor tyrosine kinases via activation of ubiquitin-specific protease 8 in lung adenocarcinoma2017

Author(s)

Organizer

Data Source

[Presentation] Stratifin accelerates progression of lung adenocarcinoma at an early stage2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Shiba Aya 柴綾

Shib Aya 柴綾