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Shiba Aya  柴 綾

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Shib Aya  柴 綾

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Researcher Number 50708427
Other IDs
Affiliation (Current) 2025: 筑波大学, 医学医療系, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2025: 筑波大学, 医学医療系, 准教授
2017 – 2019: 筑波大学, 医学医療系, 助教
2014 – 2015: 筑波大学, 医学医療系, 助教
Review Section/Research Field
Principal Investigator
Human pathology / Transformative Research Areas, Section (IV) / Basic Section 49020:Human pathology-related
Except Principal Investigator
Basic Section 49020:Human pathology-related
Keywords
Principal Investigator
肺腺癌 / 初期悪性化 / OCIAD2 / ミトコンドリア / アポトーシス / リサイクリング / チロシンキナーゼ / USP8 / SFN / 受容体型チロシンキナーゼ … More / 脱ユビキチン化 / トランスジェニックマウス / リン酸化cyclin E1 / stratifin / SKP1 / Stratifin … More
Except Principal Investigator
KRAS / 胃腸上皮型 / 肺腺癌 / 肺癌 / 胃腸上皮分化 / HNF4A / Non-TRU / neuroendocrine tumor / lung adenocarcinoma / non-TRU type / TTF-1 / HNF4α Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (9 People)
  •  宇宙及び地上実験検体の空間マルチオミックス測定プラットフォームの整備Principal Investigator

    • Principal Investigator
      柴 綾
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      University of Tsukuba
  •  Elucidation of mechanisms of carcinogenesis, metastasis, and metabolism based on histological characteristics of HNF4alpha-positive lung adenocarcinoma

    • Principal Investigator
      松原 大祐
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      University of Tsukuba
  •  Functional analysis of OCIAD2 localized at mitochondria in lung adenocarcinomaPrincipal Investigator

    • Principal Investigator
      Shib Aya
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      University of Tsukuba
  •  Molecular mechanism for stabilization of RTKs proteins by SFN in lung adenocarcinoma.Principal Investigator

    • Principal Investigator
      Shiba Aya
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      University of Tsukuba
  •  Analysis for molecular mechanism of SFN-induced lung adenocarcinoma progressionPrincipal Investigator

    • Principal Investigator
      Shiba Aya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      University of Tsukuba

All 2018 2017 2015 2014

All Journal Article Presentation

  • [Journal Article] Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma2018

    • Author(s)
      Kim Yunjung、Shiba-Ishii Aya、Nakagawa Tomoki、Iemura Shun-ichiro、Natsume Tohru、Nakano Noriyuki、Matsuoka Ryota、Sakashita Shingo、Lee SangJoon、Kawaguchi Atsushi、Sato Yukio、Noguchi Masayuki
    • Journal Title

      Oncogene

      Volume: 37 Issue: 40 Pages: 5387-5402

    • DOI

      10.1038/s41388-018-0342-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05192, KAKENHI-PROJECT-17K15634
  • [Journal Article] Stratifin accelerates progression of lung adenocarcinoma at an early stage.2015

    • Author(s)
      Shiba-Ishii A, Kim Y, Shiozawa T, Iyama S, Satomi K, Kano J, Sakashita S, Morishita Y, Noguchi M.
    • Journal Title

      Molecular Cancer

      Volume: 14 Issue: 1 Pages: 142-142

    • DOI

      10.1186/s12943-015-0414-1

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860230, KAKENHI-PROJECT-25293086
  • [Journal Article] Moesin overexpression is a unique biomarker of adenomyosis.2014

    • Author(s)
      Ohara R, Michikami H, Nakamura Y, Sakata A, Sakashita S, Satomi K, Shiba-Ishii A, Kano J, Yoshikawa H, Noguchi M.
    • Journal Title

      Pathol Int.

      Volume: 64 Issue: 3 Pages: 115-122

    • DOI

      10.1111/pin.12148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670693, KAKENHI-PROJECT-26860230
  • [Journal Article] Immunocytochemical staining for stratifin and OCIAD2 in bronchial washing specimens increases sensitivity for diagnosis of lung cancer.2014

    • Author(s)
      Itoguchi N1, Nakagawa T, Murata Y, Li D, Shiba-Ishii A, Minami Y, Noguchi M.
    • Journal Title

      Cytopathology.

      Volume: - Issue: 6 Pages: 354-361

    • DOI

      10.1111/cyt.12220

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293086, KAKENHI-PROJECT-26670172, KAKENHI-PROJECT-26860230
  • [Presentation] Stratifin interaction with USP8 is regulated by PP1 and AKT for stabilization of EGFR in lung adenocarcinoma.2018

    • Author(s)
      Kim Yunjung、柴綾、野口雅之
    • Organizer
      6th JCA-AACR joint meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15634
  • [Presentation] Stratifin regulates stabilization of receptor tyrosine kinases via activation of ubiquitin-specific protease 8 in lung adenocarcinoma2017

    • Author(s)
      Aya Shiba, YunJung Kim, and Masayuki Noguchi
    • Organizer
      18th World Conference on Lung Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15634
  • [Presentation] Stratifin accelerates progression of lung adenocarcinoma at an early stage2015

    • Author(s)
      Aya Shiba-Ishii, Yunjung Kim, Toshihiro Shiozawa, Shinji Iyama, Yukio Morishita, and Masayuki Noguchi
    • Organizer
      World Conference on Lung Cancer
    • Place of Presentation
      Denver Convention Center (USA)
    • Year and Date
      2015-09-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860230
  • 1.  野口 雅之 (00198582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  松原 大祐 (80415554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  武田 憲彦 (40422307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  伊東 剛 (20733075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  村上 善則 (30182108)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Kim Yunjung
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  NATSUME Tohru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  KAWAGUCHI Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  吉川 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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