Taniguchi Masanari 谷口将済

… Alternative Names

谷口将済タニグチマサナリ

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Researcher Number	50710696
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 摂南大学, 薬学部, 助教 2015 – 2017: 摂南大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Physical pharmacy
Keywords	Principal Investigator 凝集 / 二次構造変化 / 神経細胞死 / 銅イオン / /銅イオン / アミロイド-β / 金属イオン / アミロイドβ / アルツハイマー病 Except Principal Investigator Caspase-3 … More / Catalytide / 銅 / アポトーシス / 構造変化 / 凝集性 / チオフラビンT / CDスペクトル / 分子間相互作用 / 銅イオン / プリオンタンパク質 / フラグメントペプチド / CD / 立体構造 / 凝集 / プリオンタンパク Less

Analysis of the mechanism of amyloid-beta toxicity using model peptides which displays metal ion-dependent aggregate formation.Principal Investigator
- Principal Investigator
  
  Taniguchi Masanari
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Setsunan University
Physical and chemical analyses of aggregation mechanism by using Prion fragment peptides
- Principal Investigator
  
  Akizawa Toshifumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Setsunan University

All 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Binding of Cu2+ to Aβ1-29 causes aggregation and toxicity in SH-SY5Y cells2021
- Author(s)
  Taniguchi Masanari、Saito Mayu、Kuga Takahisa、Yamagishi Nobuyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 617-623
- DOI
  10.1016/j.bbrc.2020.11.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16362
[Journal Article] Structure-activity relationship of 5-mer peptides derived from JAL-TA92018
- Author(s)
  Rina Nakamura, Yusuke Hatakawa, Masanari Taniguchi, Motomi Konishi, Toshifumi Akizawa
- Journal Title
  
  Peptide Science 2017
  
  Volume: なし Pages: 40-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] Comparison of proteolytic activity of 5-mer peptides derived from BoxA domain of Tob/BTG family proteins2018
- Author(s)
  Yusuke Hatakawa, Rina Nakamura, Masanari Taniguchi, Motomi Konishi, Toshifumi Akizawa
- Journal Title
  
  Peptide Science 2017
  
  Volume: なし Pages: 102-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] MMP-7 cleaves amyloid β fragment peptides and copper ion inhibits the degradation2017
- Author(s)
  Taniguchi Masanari、Matsuura Kazuki、Nakamura Rina、Kojima Aya、Konishi Motomi、Akizawa Toshifumi
- Journal Title
  
  BioMetals
  
  Volume: 30 Issue: 5 Pages: 797-807
- DOI
  10.1007/s10534-017-0048-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] THE SYNTHETIC PEPTIDE DERIVED FROM BOXA REGION IN ANA/BTG3 PROTEIN IS THE SECOND CATALYTIDE CLEAVING THE AMYLOID-β PEPTIDE2017
- Author(s)
  4.Yusuke Hatakawa, Rina Nakamura, Masanari Taniguchi, Motomi Konishi, Miho Tokumasu, Tadashi Yamamoto, Toshifumi Akizawa
- Journal Title
  
  Peptide Science 2016
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] THE NOVEL FINFING OF SERINE PROTEASE-LIKE PEPTIDE2017
- Author(s)
  3.Rina Nakamura, Aya Kojima, Masanari Taniguchi, Motomi Konishi, Miho Tokumasu, Tadashi Yamamoto
- Journal Title
  
  Peptide Science 2016
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] C-terminal Region of the hPrP Can Be the Core for the Structural Conversion and Aggregation2016
- Author(s)
  Aya Kojima, Yuko Sakaguchi, Hidenao Toyoda, Masanari Taniguchi, Motomi Konishi, Toshifumi Akizawa
- Journal Title
  
  Peptide Science 2015
  
  Volume: なし Pages: 217-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] STRACTURAL ANALYSIS OF THE NOVEL HYDROLASE-LIKE PEPTIDE2016
- Author(s)
  1.R. Nakamura, M. Konishi, E. Ushijima, R. Tanaka, M. Taniguchi, A. Kojima, M. Tokumasu, T. Yamamoto, T. Akizawa
- Journal Title
  
  Peptides 2016
  
  Volume: -
- Open Access
- Data Source
  KAKENHI-PROJECT-15K07908
[Journal Article] FINDING OF THE NOVEL HYDROLASE-LIKE PEPTIDE (JAL-TA9) DIGESTING Aβ PROTEIN2016
- Author(s)
  2.T. Akizawa, R. Nakamura, A. Kojima, M. Konishi, M. Taniguchi, M. Tokumasu, T. Yamamoto
- Journal Title
  
  Peptides 2016
  
  Volume: -
- Open Access
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Aβ1-29 の神経細胞毒性に対する金属イオンの影響.2019
- Author(s)
  谷口将済 , 惣馬一貴 , 川戸満里菜 , 田中浩貴 , 久家貴寿 , 山岸伸行
- Organizer
  第30回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16362
[Presentation] Effect of Copper and Zinc on the aggregation and cytotoxicity of the Aβ-derived fragment peptide2019
- Author(s)
  Masanari Taniguchi, Kazuki Souma, Marina Kawato, Hiroki Tanaka, Takahisa Kuga, Nobuyuki Yamagishi
- Organizer
  The 6th Meeting of International Society for Zinc Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16362
[Presentation] ヒトプリオンタンパク質C-端由来ペプチドhPrP180-192 の凝集性に対する１アミノ酸変異の影響2018
- Author(s)
  坂口裕子、中村里菜、幡川祐資、谷口将済、小西元美、秋澤俊史、津田正博、豊田英尚
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] In silicoによるβアミロイドペプチドを加水分解する5残基Catalytideの立体構造2018
- Author(s)
  小西元美、中村里菜、佐々木輝、幡川祐資、谷口将済、秋澤俊史
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Catalytides are the attractive hydrolase-peptide for the strategic development of new drugs for neurotoxic diseases prevention and treatment2017
- Author(s)
  Toshifumi Akizawa, Rina Nakamura, Yusuke Hatakawa, Masanari Taniguchi, Motomi Konishi
- Organizer
  10 th GENERAL MEETING OF THE INTERNATIONAL PROTEOLYSIS SOCIETY
- Invited
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ANA/BTG3 由来酵素ペプチド (Catalytide) のアミロイド-β 切断活性2017
- Author(s)
  幡川祐資、中村里菜、小西元美、谷口将済、徳増美穂、山本雅、秋澤俊史
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ヒトプリオンタンパク質C 末端由来ペプチドの凝集性とCu2+の影響2017
- Author(s)
  坂口裕子、中村里菜、幡川祐資、谷口将済、小西元美、小嶋絢、豊田英尚、秋澤俊史
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Tob1 タンパク質由来のCatalytide の活性構造2017
- Author(s)
  小西元美、中村里菜、幡川祐資、谷口将済、牛島恵美梨、田中龍一郎、山本雅、秋澤俊史
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Catalytide のβ-アミロイドペプチドに対する結合性2017
- Author(s)
  谷口将済、中村里菜、西口杏奈、幡川祐資、小西元美、秋澤俊史
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] The Development of the novel 5-Mer Catlytide cleaving Amyloid beta peptide2017
- Author(s)
  Rina Nakamura, Yusuke Hatakawa, Motomi Konishi, Masanari Taniguchi, Toshifumi Akizawa
- Organizer
  10 th GENERAL MEETING OF THE INTERNATIONAL PROTEOLYSIS SOCIETY
- Invited
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ANA タンパク質の Box A 由来フラグメントペプチドはアミロイドβを分解する2016
- Author(s)
  幡川祐資、中村里菜、小嶋絢、谷口将済、小西元美、山本雅、秋澤俊史
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] 酵素活性をもつペプチドの CD による二次構造解析2016
- Author(s)
  小西元美、中村里菜、小嶋絢、谷口将済、山本雅、秋澤俊史
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] THE SYNTHETIC PEPTIDE DERIVED FROM BOXA REGION IN ANA/BTG3 PROTEIN IS THE SECOND CATALYTIDE CLEAVING THE AMYLOID-β PEPTIDE2016
- Author(s)
  Yusuke Hatakawa, Rina Nakamura, Masanari Taniguchi, Motomi Konishi, Miho Tokumasu, Tadashi Yamamoto, Toshifumi Akizawa
- Organizer
  The 53rd Japanese Peptide Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Catalytide と β-アミロイドペプチドとの結合2016
- Author(s)
  谷口将済、中村里菜、西口杏奈、幡川祐資、小西元美、秋澤俊史
- Organizer
  第5回新アミノ酸分析研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Chemical and Physical Properties of the Novel Serine Protease-Like Peptide Digesting Amyloid-Beta Protein2016
- Author(s)
  Rina Nakamura, Masanari Taniguchi, Motomi Konishi, Emiri Ushijina, Ryuichiro Tanaka, Aya Kojima, Miho Tokumasu, Tadashi Yamamoto, Toshifumi Akizawa
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ペプチド性酵とβ-アミロイドペプチドとの結合性2016
- Author(s)
  谷口将済、中村里菜、西口杏奈、幡川祐資、小嶋絢、小西元美、徳増美穂、山本雅、秋澤俊史
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ANA/BTG3 由来 Catalytide のアミロイド-β 切断活性2016
- Author(s)
  幡川祐資、中村里菜、谷口将済、小西元美、山本雅2、秋澤俊史演題名：ANA/BTG3 由来 Catalytide のアミロイド-β 切断活性
- Organizer
  第5回新アミノ酸分析研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] STRACTURAL ANALYSIS OF THE NOVEL HYDROLASE-LIKE PEPTIDE2016
- Author(s)
  R. Nakamura, M. Konishi, E. Ushijima, R. Tanaka, M. Taniguchi, A. Kojima, M. Tokumasu, T. Yamamoto, T. Akizawa
- Organizer
  34th European Peptide Symposium
- Place of Presentation
  Germany-Leipzig
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] FINDING OF THE NOVEL HYDROLASE-LIKE PEPTIDE (JAL-TA9) DIGESTING Aβ PROTEIN2016
- Author(s)
  T. Akizawa, R. Nakamura, A. Kojima, M. Konishi, M. Taniguchi, M. Tokumasu, T. Yamamoto
- Organizer
  34th European Peptide Symposium
- Place of Presentation
  Germany-Leipzig
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] 酵素活性をもつペプチドのコンフォメーション解析2016
- Author(s)
  牛島恵美梨、小西元美、中村里菜、田中龍一郎、谷口将済、秋澤俊史
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Tob1 タンパク質由来の Catalytide の立体構造2016
- Author(s)
  小西元美、中村里菜、幡川祐資、谷口将済、田中龍一朗、秋澤俊史
- Organizer
  第5回新アミノ酸分析研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] アミロイドβを分解する低分子ペプチドの発見2016
- Author(s)
  中村里菜、小嶋絢、小西元美、谷口将済、牛島恵美梨、田中龍一郎、徳増美穂、山本雅、秋澤俊史
- Organizer
  21回病態プロテアーゼ学会
- Place of Presentation
  大阪
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ヒトプリオンタンパク質（hPrP）C-末端領域由来フラグメントペプチドの構造変化と分子間相互作用の検討2016
- Author(s)
  坂口裕子、小嶋絢、豊田英尚、谷口将済、小西元美、秋澤俊史
- Organizer
  日本薬学会第136年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] ヒトプリオンタンパク質由来フラグメントペプチドのSH-SY5Y細胞への影響2016
- Author(s)
  大藤敏男、小嶋絢、坂口裕子、豊田英尚、谷口将済、小西元美、秋澤俊史
- Organizer
  日本薬学会第136年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] THE NOVEL FINFING OF SERINE PROTEASE-LIKE PEPTIDE2016
- Author(s)
  Rina Nakamura, Aya Kojima, Masanari Taniguchi, Motomi Konishi, Miho Tokumasu, Tadashi Yamamoto, Toshifumi Akizawa
- Organizer
  The 53rd Japanese Peptide Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Catalytideの発見2016
- Author(s)
  秋澤俊史、中村里菜、幡川祐資、谷口将済、小西元美、小嶋絢　徳増美穂、山本雅
- Organizer
  第5回新アミノ酸分析研究会
- Place of Presentation
  東京
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] Discover of the Novel Serine Protease-like Peptide digesting Amyloid-Beta Protein2016
- Author(s)
  Toshifumi Akizawa, Rina Nakamura, Aya Kojima, Motomi Konishi, Masanari Taniguchi, Motomi Konishi, Miho Tokumasu, Tadashi Yamamoto
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] 合成フラグメントペプチドを用いたヒトプリオンタンパク質（PrP）C-末端領域の性質解2015
- Author(s)
  小嶋絢、坂口裕子、永井裕子、豊田英尚、谷口将済、小西元美、秋澤俊史
- Organizer
  第28回バイオメディカル分析科学シンポジウム
- Place of Presentation
  長崎県長崎市
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K07908
[Presentation] C-terminal region of the hPrP can be the core for the structual conversion and the aggregation2015
- Author(s)
  Aya Kojima, Yuko Sakaguchi, Hidenao Toyoda, Masanari Taniguchi, Motomi Konishi, Toshifumi Akizawa
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  神奈川県平塚市
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K07908

1. Akizawa Toshifumi (30202526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 34 results
2. 小西元美 (20229446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 35 results

Taniguchi Masanari 谷口 将済

谷口 将済 タニグチ マサナリ

Research Projects

Research Products

Co-Researchers

Analysis of the mechanism of amyloid-beta toxicity using model peptides which displays metal ion-dependent aggregate formation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physical and chemical analyses of aggregation mechanism by using Prion fragment peptides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Binding of Cu2+ to Aβ1-29 causes aggregation and toxicity in SH-SY5Y cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure-activity relationship of 5-mer peptides derived from JAL-TA92018

Author(s)

Journal Title

Data Source

[Journal Article] Comparison of proteolytic activity of 5-mer peptides derived from BoxA domain of Tob/BTG family proteins2018

Author(s)

Journal Title

Data Source

[Journal Article] MMP-7 cleaves amyloid β fragment peptides and copper ion inhibits the degradation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] THE SYNTHETIC PEPTIDE DERIVED FROM BOXA REGION IN ANA/BTG3 PROTEIN IS THE SECOND CATALYTIDE CLEAVING THE AMYLOID-β PEPTIDE2017

Author(s)

Journal Title

Data Source

[Journal Article] THE NOVEL FINFING OF SERINE PROTEASE-LIKE PEPTIDE2017

Author(s)

Journal Title

Data Source

[Journal Article] C-terminal Region of the hPrP Can Be the Core for the Structural Conversion and Aggregation2016

Author(s)

Journal Title

Data Source

[Journal Article] STRACTURAL ANALYSIS OF THE NOVEL HYDROLASE-LIKE PEPTIDE2016

Author(s)

Journal Title

Data Source

[Journal Article] FINDING OF THE NOVEL HYDROLASE-LIKE PEPTIDE (JAL-TA9) DIGESTING Aβ PROTEIN2016

Author(s)

Journal Title

Data Source

[Presentation] Aβ1-29 の神経細胞毒性に対する金属イオンの影響.2019

Author(s)

Organizer

Data Source

[Presentation] Effect of Copper and Zinc on the aggregation and cytotoxicity of the Aβ-derived fragment peptide2019

Author(s)

Organizer

Data Source

[Presentation] ヒトプリオンタンパク質C-端由来ペプチドhPrP180-192 の凝集性に対する１アミノ酸変異の影響2018

Author(s)

Organizer

Data Source

[Presentation] In silicoによるβアミロイドペプチドを加水分解する5残基Catalytideの立体構造2018

Author(s)

Organizer

Data Source

[Presentation] Catalytides are the attractive hydrolase-peptide for the strategic development of new drugs for neurotoxic diseases prevention and treatment2017

Author(s)

Organizer

Data Source

[Presentation] ANA/BTG3 由来酵素ペプチド (Catalytide) のアミロイド-β 切断活性2017

Author(s)

Organizer

Place of Presentation

Year and Date

Taniguchi Masanari 谷口将済

谷口将済タニグチマサナリ