Tanaka Yasuyoshi 田中泰圭

Researcher Number	50714466
Other IDs
Affiliation (Current)	2025: 福岡大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 福岡大学, 薬学部, 助教 2022: 第一薬科大学, 薬学部, 非常勤講師 2014 – 2021: 福岡大学, てんかん分子病態研究所, ポスト・ドクター
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator iPS細胞 / SCN1A / 脳オルガノイド / 発達性てんかん性脳症 / 疾患モデル / Dravet症候群 / 神経変性 / GABA作動性神経細胞 / 疾患特異的iPS細胞 / Nav1.1 … More / ドラベ症候群 / てんかん / 脳オルガノイド疾患モデル / ex vivo病態モデル / 終脳オルガノイド / 病態モデル / 遺伝子修復 / GABA作動性神経 / genome editing / 神経分化 / 遺伝子編集 / 疾患iPS細胞モデル / Dravte症候群 / 抑制性神経 / 興奮性神経 / ゲノム編集 / TALEN … More Except Principal Investigator iPS細胞 / てんかん / 時間治療 / パーキンソン病 / 時間薬理学 / 経鼻投与 / αシヌクレイン / ヒトiPS細胞 / 脳ペリサイト / アストロサイト / 神経作動薬 / 根治薬 / チャネル / けいれん / 半導体加工 / 微小電極アレイ / 脳オルガノイド Less

脳オルガノイド間の相互作用を解析する微小電極アレイデバイス
- Principal Investigator
  
  安田隆
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyushu Institute of Technology
腹側前脳オルガノイド疾患モデルを活用して発達性てんかん性脳症の神経変性病態に迫るPrincipal Investigator
- Principal Investigator
  
  田中泰圭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fukuoka University
Establishment of a practical pipeline to develop drugs for intractable epilepsies based on their uncovered molecular pathomechanisms
- Principal Investigator
  
  廣瀬伸一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fukuoka University
Mechanisms of neuronal circuit pathogenesis and exploring for therapeutic agents using iPS Cell induced astrocytes from epilepsy patients
- Principal Investigator
  
  桂林秀太郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Fukuoka University
Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes
- Principal Investigator
  
  道具伸也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Fukuoka University
DravetPrincipal Investigator
- Principal Investigator
  
  Tanaka Yasuyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fukuoka University
  Daiichi University, College of Pharmaceutical Sciences
Brain organoids as pathological model for Dravet syndrome applicable to drug discovery researchPrincipal Investigator
- Principal Investigator
  
  TANAKA Yasuyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fukuoka University
Identification of therapeutic targets and drug discovery research for Dravet syndrome using iPSCs modelPrincipal Investigator
- Principal Investigator
  
  Tanaka Yasuyoshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Fukuoka University

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 Other

All Journal Article Presentation

[Journal Article] Astrocyte Ca2+ signaling is facilitated in Scn1a+/? mouse model of Dravet syndrome2023
- Author(s)
  Uchino Kouya、Tanaka Yasuyoshi、Ikezawa Wakana、Deshimaru Masanobu、Kubota Kaori、Watanabe Takuya、Katsurabayashi Shutaro、Iwasaki Katsunori、Hirose Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 643 Pages: 169-174
- DOI
  10.1016/j.bbrc.2022.12.084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07784, KAKENHI-PROJECT-20H03651, KAKENHI-PROJECT-20H04506
[Journal Article] Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes2022
- Author(s)
  Uchino Kouya、Tanaka Yasuyoshi、Kawaguchi Sayaka、Kubota Kaori、Watanabe Takuya、Katsurabayashi Shutaro、Hirose Shinichi、Iwasaki Katsunori
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 8 Pages: 104762-104762
- DOI
  10.1016/j.isci.2022.104762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07784, KAKENHI-PROJECT-20H03651, KAKENHI-PROJECT-20H04506
[Journal Article] 人工多能性幹細胞 (iPSC) を利用した病態解析2022
- Author(s)
  田中泰圭
- Journal Title
  
  Epilepsy
  
  Volume: 16 Pages: 111-119
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07784
[Journal Article] Application of induced pluripotent stem cells in epilepsy2020
- Author(s)
  Hirose Shinichi、Tanaka Yasuyoshi、Shibata Mami、Kimura Yuichi、Ishikawa Mitsuru、Higurashi Norimichi、Yamamoto Toshiyuki、Ichise Eisuke、Chiyonobu Tomohiro、Ishii Atsushi
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 108 Pages: 103535-103535
- DOI
  10.1016/j.mcn.2020.103535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17347, KAKENHI-PROJECT-19K17381, KAKENHI-PROJECT-20H03651, KAKENHI-PROJECT-18K07802, KAKENHI-PROJECT-18K07803, KAKENHI-PROJECT-18K15735
[Journal Article] Establishment of human induced pluripotent stem cells derived from skin cells of a patient with Dravet syndrome.2020
- Author(s)
  Kimura Y, Tanaka Y, Shirasu N, Yasunaga S, Higurashi N, Hirose S.
- Journal Title
  
  Stem Cell Res.
  
  Volume: 47 Pages: 101857-101857
- DOI
  10.1016/j.scr.2020.101857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08828, KAKENHI-PROJECT-20H03651, KAKENHI-PROJECT-18K07802, KAKENHI-PROJECT-18K15735
[Journal Article] Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene2018
- Author(s)
  Tanaka Yasuyoshi、Sone Takefumi、Higurashi Norimichi、Sakuma Tetsushi、Suzuki Sadafumi、Ishikawa Mitsuru、Yamamoto Takashi、Mitsui Jun、Tsuji Hitomi、Okano Hideyuki、Hirose Shinichi
- Journal Title
  
  Stem Cell Research
  
  Volume: 28 Pages: 100-104
- DOI
  10.1016/j.scr.2018.01.036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-26461552, KAKENHI-PROJECT-16K18478, KAKENHI-PROJECT-26860833, KAKENHI-PROJECT-18K07802, KAKENHI-PROJECT-15H02548, KAKENHI-PROJECT-16K15532
[Presentation] 脳ペリサイトのα-Synucleinクリアランスに対するmetforminおよびexendin-4の効果2024
- Author(s)
  横谷みき、根本真奈、得能七海、髙田芙友子、松本純一、岩尾卓朗、田中泰圭、佐野和憲、道具伸也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] α-Synucleinクリアランス能を有するヒトiPS細胞由来脳ペリサイトの作製2024
- Author(s)
  横谷みき、田中泰圭、高田芙友子、松本純一、岩尾卓朗、佐野和憲、道具伸也
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Aβ暴露アストロサイトによるシナプス病態の発現とヒトiPS細胞の活用2023
- Author(s)
  桂林秀太郎, 大藪康平, 内野鉱也, 田中泰圭, 窪田香織, 渡辺拓也, 廣瀨伸一, 岩崎克典
- Organizer
  第64回日本神経病理学会総会学術研究会/ 第66回日本神経化学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27496
[Presentation] ヒトiPS細胞から誘導した脳オルガノイドの発生過程におけるタバコ主成分の影響2023
- Author(s)
  田中泰圭、藤本伊依那、西田朱里、道具伸也
- Organizer
  第13回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] ヒトiPS細胞から誘導した前脳オルガノイドの神経発生における高温加熱式たばこ主流煙抽出物の影響2023
- Author(s)
  田中泰圭、藤本伊依那、西田朱里、堀之内孝広、道具伸也
- Organizer
  日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] パーキンソン病の病態進展における血液脳関門の関与2023
- Author(s)
  道具伸也、高田芙友子、岩尾卓朗、田中泰圭、横谷みき、佐野和憲
- Organizer
  第66回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 脳ペリサイトのα-Synucleinクリアランスを促進する治療薬の探索2023
- Author(s)
  横谷みき、髙田芙友子、松本純一、岩尾卓朗、田中泰圭、安永美保、佐野和憲、道具伸也
- Organizer
  第76回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] The establishment of a novel autaptic culture system equipped with human-induced pluripotent stem cell-derived astrocytes.2022
- Author(s)
  Kouya Uchino, Yasuyoshi Tanaka, Sayaka Kawaguchi, Kaori Kubota, Takuya Watanabe, Shutaro Katsurabayashi, Shinichi Hirose & Katsunori Iwasaki.
- Organizer
  Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] 神経変性疾患の病態解明に資するiPS細胞由来アストロサイトによる最小神経回路の構築.2022
- Author(s)
  内野鉱也, 田中泰圭, 川口紗果, 渡辺拓也, 窪田香織, 桂林秀太郎, 廣瀬伸一, 岩崎克典.
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] Dravet症候群モデルマウスであるScn1a+/-マウスは細胞外Ca2+濃度が増加するとシナプス伝達の興奮性と抑制性のバランスが崩壊する.2022
- Author(s)
  内野鉱也, 河野洋幸, 田中泰圭, 安谷屋友菜, 朝原愛, 弟子丸正伸, 渡辺拓也, 窪田香織, 桂林秀太郎, 廣瀬伸一, 岩崎克典.
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] ヒト iPS細胞由来アストロサイトと共培養した単一ニューロンの興奮性シナプス機能解析.2022
- Author(s)
  内野鉱也, 田中泰圭, 川口紗果, 渡辺拓也, 窪田香織, 桂林秀太郎, 廣瀬伸一, 岩崎克典.
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] Basic study of pathogenesis of epilepsy by means of iPS cell.2021
- Author(s)
  Yasuyoshi TANAKA
- Organizer
  the 13th Asian & Oceanian Epilepsy Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07784
[Presentation] Basic study of pathogenesis of epilepsy by means of iPS cell2021
- Author(s)
  Yasuyoshi TANAKA
- Organizer
  the 13th Asian & Oceanian Epilepsy Congress (AOEC)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] Scn1a KOマウス海馬由来抑制性神経細胞の機能解析.2019
- Author(s)
  田中泰圭, モレイラケビン, 廣瀬伸一.
- Organizer
  NEURO2019 (第42回日本神経科学学会・第62回日本神経化学会大会合同大会).
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] A MUTATION IN SCN1A SELECTIVELY IMPAIRS IPSCS-DERIVED INHIBITORY NEURONS DERIVED FROM A PATIENT WITH DRAVET SYNDROME.2019
- Author(s)
  Y. Tanaka, M. Ishikawa, N. Higurashi, H. Okano, S. Hirose.
- Organizer
  The International Society of Stem Cell Research 2019 Annual Meeting (ISSCR 2019).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] Physiological Characterization of neurons derived from Dravet syndrome iPSCs models.2019
- Author(s)
  Y. Tanaka, M. Ishikawa, N. Higurashi, H. Okano, S. Hirose.
- Organizer
  The 15th Asian and Oceania Congress of Child Neurology (15th AOCCN).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] MEAシステムを用いたDravet症候群患者iPS細胞由来神経細胞の機能解析.2019
- Author(s)
  田中泰圭, 石川充, 日暮憲道, 岡野栄之, 廣瀬伸一.
- Organizer
  第53回日本てんかん学会学術集会.
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] In-Vitro Hippocampal Inhibitory Neuronal activity of SCN1A KO Mice and a Potential Alternative Treatment Path.2018
- Author(s)
  K. Moreira, Y. Tanaka, S. Hirose.
- Organizer
  the American Epilepsy Society annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15735
[Presentation] Generation of isogenic iPS cell line model for Dravet syndrome using TALEN-mediated genome editing of SCN1A gene2016
- Author(s)
  Y. Tanaka, T. Sone, N. Higurashi, T. Uchida, M. Ishikawa, H. Okano, S. Hirose
- Organizer
  the 21st Korean Epilepsy Congress (KEC 2016)
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2016-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860833
[Presentation] What was revealed by whole genome sequence analysis of genome edited patient-derived disease iPSCs.2015
- Author(s)
  Takefumi Sone, Sung-Joon Park, Yasuyoshi Tanaka, Etsuro Ohta, Norimichi Higurashi, Kenta Nakai, Shinichi Hirose, Hideyuki Okano.
- Organizer
  BMB2015
- Place of Presentation
  横浜（日本）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860833
[Presentation] Genome editing of SCN1A in induced pluripotent stem cells to study the pathomechanisms of Dravet syndrome.2015
- Author(s)
  Yasuyoshi Tanaka, Takehumi Sone, Norimichi Higurashi, Taku Uchida, Mitsuru Ishikawa, Hideyuki Okano, Shinichi Hirose.
- Organizer
  13th AOCCN
- Place of Presentation
  台北 (台湾)
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860833
[Presentation] TALEN-mediated genome editing of patient-derived iPSCs for disease model studies.2015
- Author(s)
  Takefumi Sone, Yasuyoshi Tanaka, Etsuro Ohta, Makoto Hosoya、Naoki Ichiyanagi, Tetsuya Akiyama, Norimichi Higurashi、Shinichi Hirose, Hideyuki Okano.
- Organizer
  Conference on Transposition and Genome Engineering 2015
- Place of Presentation
  奈良(日本)
- Year and Date
  2015-11-17
- Data Source
  KAKENHI-PROJECT-26860833
[Presentation] TALEN-mediated genome editing of patient-derived iPSCs for disease model studies
- Author(s)
  Takefumi sone, Yasuyoshi Tanaka, Etsuro Ohta, Naoki Ichiyanagi, Norimichi Higurashi, Shinichi Hirose, Hideyuki Okano
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-18 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-26860833
[Presentation] TALEN-mediated genome editing of patient-derived iPSCs for disease model studies
- Author(s)
  Takefumi sone, Yasuyoshi Tanaka, Etsuro Ohta, Naoki Ichiyanagi, Norimichi Higurashi, Shinichi Hirose, Hideyuki Okano
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-24 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-26860833

1. 桂林秀太郎 (50435145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 道具伸也 (60399186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 安田隆 (80270883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 廣瀬伸一 (60248515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 荻原郁夫 (30373286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山本英明 (10552036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 牛島健太郎 (70448843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高田芙友子 (70412575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 岩尾卓朗 (30846374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. SASAGURI Yukari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 曽根岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 柴田磨己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 安永晋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 白須直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Yasuyoshi 田中 泰圭

Research Projects

Research Products

Co-Researchers

脳オルガノイド間の相互作用を解析する微小電極アレイデバイス

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腹側前脳オルガノイド疾患モデルを活用して発達性てんかん性脳症の神経変性病態に迫るPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a practical pipeline to develop drugs for intractable epilepsies based on their uncovered molecular pathomechanisms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of neuronal circuit pathogenesis and exploring for therapeutic agents using iPS Cell induced astrocytes from epilepsy patients

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DravetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Brain organoids as pathological model for Dravet syndrome applicable to drug discovery researchPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of therapeutic targets and drug discovery research for Dravet syndrome using iPSCs modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Astrocyte Ca2+ signaling is facilitated in Scn1a+/? mouse model of Dravet syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 人工多能性幹細胞 (iPSC) を利用した病態解析2022

Author(s)

Journal Title

Data Source

[Journal Article] Application of induced pluripotent stem cells in epilepsy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of human induced pluripotent stem cells derived from skin cells of a patient with Dravet syndrome.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene2018

Author(s)

Journal Title

DOI

Tanaka Yasuyoshi 田中泰圭