Watanabe Hitoshi 渡邉一史

Researcher Number	50721495
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2019: 金沢大学, 新学術創成研究機構, 特任助教 2016 – 2017: 金沢大学, 新学術創成研究機構, 研究協力員 2014 – 2015: 金沢大学, 脳・肝インターフェースメディシン研究センター, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Eating habits / Endocrinology
Keywords	Principal Investigator 肝臓 / 糖取り込み / 栄養学 / 蛋白質 / タンパク質 / 食品 / NAFLD / 脂肪肝 / 糖尿病 / ストレス / 糖代謝

GKRPアセチル化制御による肝糖取り込みメカニズムの解明Principal Investigator
- Principal Investigator
  
  渡邉一史
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kanazawa University
Dietary protein reduces hepatic steatosis and prevents non-alcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  Watanabe Hitoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa University
Effect of ATF3 induced by stress on glucose metabolism in the liverPrincipal Investigator
- Principal Investigator
  
  Watanabe Hitoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kanazawa University

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Nicotinic alpha‐7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non‐alcoholic steatohepatitis2019
- Author(s)
  Kimura Kumi、Inaba Yuka、Watanabe Hitoshi、Matsukawa Toshiya、Matsumoto Michihiro、Inoue Hiroshi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10 Issue: 3 Pages: 659-666
- DOI
  10.1111/jdi.12964
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-16J08117, KAKENHI-PROJECT-18J40062, KAKENHI-PROJECT-18KT0020, KAKENHI-PROJECT-19K09192, KAKENHI-PROJECT-19K20204, KAKENHI-PROJECT-19H03713, KAKENHI-PROJECT-19K18004
[Journal Article] Dietary mung bean protein reduces high-fat diet-induced weight gain by modulating host bile acid metabolism in a gut microbiota-dependent manner.2018
- Author(s)
  Nakatani A, Li X, Miyamoto J, Igarashi J, Watanabe H, Sutou A, Watanabe K, Motoyama T, Tachibana N, Kohno M, Inoue H, Kimura I.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 501 Issue: 4 Pages: 955-961
- DOI
  10.1016/j.bbrc.2018.05.090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0020, KAKENHI-PROJECT-18K19731, KAKENHI-PROJECT-18K17920, KAKENHI-PUBLICLY-17H05499, KAKENHI-PROJECT-16J08117, KAKENHI-PROJECT-16K00849
[Journal Article] Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein2018
- Author(s)
  Watanabe Hitoshi、Inaba Yuka、Kimura Kumi、Matsumoto Michihiro、Kaneko Shuichi、Kasuga Masato、Inoue Hiroshi
- Journal Title
  
  Nat Commun.
  
  Volume: 9 Issue: 1 Pages: 30-30
- DOI
  10.1038/s41467-017-02537-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00849, KAKENHI-PUBLICLY-17H05499, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-16J08117, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-15H05678
[Journal Article] Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.2017
- Author(s)
  Watanabe H, Inaba Y, Kimura K, Asahara SI, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H*.
- Journal Title
  
  J Nutr.
  
  Volume: 147 Issue: 1 Pages: 52-60
- DOI
  10.3945/jn.116.231662
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-16J08117, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26461382, KAKENHI-PROJECT-16K00849
[Journal Article] Centra insulin-action activates Kupffer cells by suppressing hepatic vagal activation through nicotinic alpha 7 acetylcholine receptor.2016
- Author(s)
  Kimura K, Tanida M, Nagata N, Inaba Y, Watanabe H, Nagashimada M, Ota T, Asahara S, Kido Y, Matsumoto M, Toshinai K, Nakazato M, Shibamoto T, Kaneko S, Kasuga M, Inoue H
- Journal Title
  
  Cell reports
  
  Volume: 14 Issue: 10 Pages: 2362-2374
- DOI
  10.1016/j.celrep.2016.02.032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461382, KAKENHI-PROJECT-26560368, KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-25461352, KAKENHI-PROJECT-26670599, KAKENHI-PROJECT-26860693, KAKENHI-PROJECT-26860705, KAKENHI-PROJECT-26870672, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-15K12698, KAKENHI-PROJECT-16K01815, KAKENHI-PROJECT-16K09767
[Journal Article] Serotonin improves high fat diet induced obesity in mice.2016
- Author(s)
  Watanabe H.†, Nakano T.†, Saito R.†, Akasaka D., Saito K., Ogasawara H., Minashima T., Miyazawa K., Kanaya T., Takakura I., Inoue N., Ikeda I., Chen X., Miyake M., Kitazawa H., Shirakawa H., Sato K., Tahara K., Nagasawa Y., Rose M.T., Ohwada S., Watanabe K., Aso H.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1371/journal.pone.0147143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07708, KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-25450461, KAKENHI-PROJECT-26660217, KAKENHI-PROJECT-26860705
[Journal Article] Cyclophilin A is a new M cell marker of bovine intestinal epithelium.2016
- Author(s)
  Tetsuya Hondo , Shunsuke Someya , Yuya Nagasawa , Shunsuke Terada, Hitoshi Watanabe, Xiangning Chen, Kouichi Watanabe, Shyuichi Ohwada, Haruki Kitazawa, Michael T. Rose, Tomonori Nochi, Hisashi Aso
- Journal Title
  
  Cell and Tissue Research
  
  Volume: 364 Issue: 3 Pages: 585-597
- DOI
  10.1007/s00441-015-2342-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-16H06207, KAKENHI-PROJECT-16J08117, KAKENHI-PROJECT-26660245, KAKENHI-PROJECT-16K00849, KAKENHI-PROJECT-16K15021
[Journal Article] Gadd34 regulates liver regeneration in hepatic steatosis.2015
- Author(s)
  Inaba Y, Furutani T, Kimura K, Watanabe H, Haga S, Kido Y, Yamamoto Y, Harada K, Kaneko S, Oyadomari S, Ozaki M, Kasuga M, Inoue H.
- Journal Title
  
  Hepatology
  
  Volume: 61(4) Issue: 4 Pages: 1343-1356
- DOI
  10.1002/hep.27619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24591348, KAKENHI-PUBLICLY-25126709, KAKENHI-PUBLICLY-25126729, KAKENHI-PROJECT-25861179, KAKENHI-PUBLICLY-26116729, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26670599, KAKENHI-PROJECT-26860705, KAKENHI-PROJECT-26460416, KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-25461335
[Journal Article] The stimulatory effect of plasma samples from fattening cattle on adipogenesis related gene expression in preadipocyte cells2015
- Author(s)
  Hitoshi WATANABE, Xiangning CHEN, Noriaki SHOJI, Ryo SAITO, Tatsuya NAKANO, Kazuki SAITO, Keisuke SUMIYOSHI, Michael T. ROSE, Natumi OKADA, Kouichi WATANABE and Hisashi ASO
- Journal Title
  
  Animal Science Journal
  
  Volume: 86 Issue: 7 Pages: 698-706
- DOI
  10.1111/asj.12344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04586, KAKENHI-PROJECT-25450461, KAKENHI-PROJECT-26660217, KAKENHI-PROJECT-26860705
[Presentation] SIRT2による肝臓糖取り込み機構の解明2018
- Author(s)
  渡邉一史、松本道宏、春日雅人、井上啓
- Organizer
  日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K00849
[Presentation] SIRT2はグルコキナーゼ調節タンパク質の脱アセチル化を介して肝臓糖取り込みを制御する2018
- Author(s)
  渡邉一史、稲葉有香、松本道宏、春日雅人、井上啓
- Organizer
  日本肥満学会
- Data Source
  KAKENHI-PROJECT-16K00849
[Presentation] NAD+は肝糖取り込みを調節する2018
- Author(s)
  渡邉一史、稲葉有香、松本道宏、春日雅人、井上啓
- Organizer
  アディポサイエンス・シンポジウム
- Data Source
  KAKENHI-PROJECT-16K00849
[Presentation] NAD+による肝糖取り込み調節機構の解析2017
- Author(s)
  渡邉一史、稲葉有香、木村久美、松本道宏、金子周一、春日雅人、井上啓
- Organizer
  第35回内分泌代謝学サマーセミナー
- Data Source
  KAKENHI-PROJECT-16K00849
[Presentation] NAD+/SIRT2作用の低下は肝糖取り込みを障害する2017
- Author(s)
  渡邉一史、春日雅人、井上啓
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-16K00849
[Presentation] SIRT2の肝臓糖取り込みにおける重要性2016
- Author(s)
  渡邉一史、松本道宏、春日雅人、井上啓
- Organizer
  第28回分子糖尿病学シンポジウム
- Place of Presentation
  富山　タワー111
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K00849

1. OGASAWARA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 井上啓

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# of Collaborated Products: 2 results
3. 稲葉有香

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# of Collaborated Products: 1 results
4. 淺原俊一郎

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# of Collaborated Products: 1 results
5. 山本靖彦

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# of Collaborated Products: 1 results
6. 山本博

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# of Collaborated Products: 1 results
7. 渡辺康一

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# of Collaborated Products: 2 results
8. 麻生久

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# of Collaborated Products: 2 results
9. 野地智法

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# of Collaborated Products: 1 results
10. 北澤春樹

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11. 岡田夏美

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# of Collaborated Products: 1 results

Watanabe Hitoshi 渡邉 一史

Research Projects

Research Products

Co-Researchers

GKRPアセチル化制御による肝糖取り込みメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dietary protein reduces hepatic steatosis and prevents non-alcoholic fatty liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of ATF3 induced by stress on glucose metabolism in the liverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nicotinic alpha‐7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non‐alcoholic steatohepatitis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary mung bean protein reduces high-fat diet-induced weight gain by modulating host bile acid metabolism in a gut microbiota-dependent manner.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Centra insulin-action activates Kupffer cells by suppressing hepatic vagal activation through nicotinic alpha 7 acetylcholine receptor.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serotonin improves high fat diet induced obesity in mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclophilin A is a new M cell marker of bovine intestinal epithelium.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gadd34 regulates liver regeneration in hepatic steatosis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The stimulatory effect of plasma samples from fattening cattle on adipogenesis related gene expression in preadipocyte cells2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] SIRT2による肝臓糖取り込み機構の解明2018

Author(s)

Organizer

Data Source

[Presentation] SIRT2はグルコキナーゼ調節タンパク質の脱アセチル化を介して肝臓糖取り込みを制御する2018

Author(s)

Organizer

Data Source

[Presentation] NAD+は肝糖取り込みを調節する2018

Author(s)

Organizer

Data Source

[Presentation] NAD+による肝糖取り込み調節機構の解析2017

Watanabe Hitoshi 渡邉一史