Im Dohyun 林到ヒョン

Researcher Number	50721883
Other IDs	https://orcid.org/0000-0002-6939-7718
Affiliation (Current)	2024: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医学研究科, 特定助教 2015 – 2017: 京都大学, 医学研究科, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Neurochemistry/Neuropharmacology Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator GPCR / SBDD / 創薬 / 薬理学 / 構造生物学 / Cryo-EM / 統合失調症 / 抗精神薬 / D2R / ドパミン受容体 … More / 結晶構造解析 / 神経伝達物質・受容体 / 膜蛋白質 / 膜タンパク質 / X線結晶構造解析 / Gタンパク質共役受容体 … More Except Principal Investigator クライオ電子顕微鏡 / バイスシグナリング / 単粒子解析 / バイアスシグナリング / グレリン受容体 / Gタンパク質共役受容体 / 抗体 / 創薬 / 膜タンパク質 / 構造生物学 Less

膜蛋白質のクライオ電子顕微鏡システマティック解析を可能にするアプローチ
- Principal Investigator
  
  岩田想
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
A new mechanism of drug selectivity for dopamine receptorPrincipal Investigator
- Principal Investigator
  
  林到ヒョン
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kyoto University
グレリン受容体のシグナル伝達選択機構の構造基盤
- Principal Investigator
  
  浅田秀基
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
Structural Study of Human Dopamine D2 ReceptorPrincipal Investigator
- Principal Investigator
  
  Im Dohyun
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyoto University

All 2024 2023 2018 2017

All Journal Article Presentation Book

[Book] 医学のあゆみ-統合失調症の未来 ─研究と治療2023
- Author(s)
  林到炫、岩田想
- Total Pages
  7
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-23K06357
[Journal Article] Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A2A receptor2024
- Author(s)
  Araya Tsuyoshi、Matsuba Yuya、Suzuki Harufumi、Doura Tomohiro、Nuemket Nipawan、Nango Eriko、Yamamoto Masaki、Im Dohyun、Asada Hidetsugu、Kiyonaka Shigeki、Iwata So
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 695 Pages: 149393-149393
- DOI
  10.1016/j.bbrc.2023.149393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0099, KAKENHI-PLANNED-19H05777, KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-19H00923
[Journal Article] Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor2023
- Author(s)
  Im Dohyun、Kishikawa Jun-ichi、Shiimura Yuki、Hisano Hiromi、Ito Akane、Fujita-Fujiharu Yoko、Sugita Yukihiko、Noda Takeshi、Kato Takayuki、Asada Hidetsugu、Iwata So
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6538-6538
- DOI
  10.1038/s41467-023-42260-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06357, KAKENHI-PROJECT-22K19431, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923
[Journal Article] Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA2018
- Author(s)
  Suno Ryoji、Kimura Kanako Terakado、Nakane Takanori、Fujiwara Takaaki、Yamanaka Yasuaki、Im Dohyun、Rosenbaum Daniel M.、Iwata So、Shimamura Tatsuro、Kobayashi Takuya
- Journal Title
  
  Structure
  
  Volume: 26 Issue: 1 Pages: 7-19
- DOI
  10.1016/j.str.2017.11.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15K08268, KAKENHI-PROJECT-15K18376
[Journal Article] Ligand complex structures of L-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change2018
- Author(s)
  D. Im, D. Matsui, T. Arakawa, K. Isobe, Y. Asano, and S. Fushinobu
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8(3) Issue: 3 Pages: 314-324
- DOI
  10.1002/2211-5463.12387
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06169, KAKENHI-PROJECT-15K18376
[Presentation] Frontiers in the Structural Biology of GPCRs2023
- Author(s)
  林到炫
- Organizer
  第57回日本味と勾学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06357
[Presentation] 新規抗ヒスタミン薬の分子設計を目指したヒスタミンH4受容体の構造基盤2023
- Author(s)
  林到炫
- Organizer
  第23回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-23K06357
[Presentation] Structural insights into antipsychotics binding modes in dopamine D2-class receptors2018
- Author(s)
  Dohyun Im, Yasuaki Yamanaka, Takaaki Fujiwara, Takanori Nakane, Tomoko Uemura, Chihiro Mori, Kanako Kimura, Eriko Nango, Kunio Hirata, Keitaro Yamashita, So Iwata and Tatsuro Shimamura
- Organizer
  Keystone Symposia: GPCR Structure and Function - Taking GPCR Drug Development and Discovery to the Next Level (Santa Fe, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18376
[Presentation] A first novel GPCR structure determined at SACLA2017
- Author(s)
  Dohyun Im, Tatsuro Shimamura, So Iwata
- Organizer
  2017 International Symposium on Frontiers in structural biology for Drug Development (Pohang, Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18376

1. 岩田想 (60452330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 浅田秀基 (20399041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 椎村祐樹 (40551297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 堤尚孝 (70963495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SHIMAMURA Tatsuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. YAMANAKA Yasuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 藤原孝彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 浅野泰久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 松井大亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Im Dohyun 林 到ヒョン

Research Projects

Research Products

Co-Researchers

膜蛋白質のクライオ電子顕微鏡システマティック解析を可能にするアプローチ

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new mechanism of drug selectivity for dopamine receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グレリン受容体のシグナル伝達選択機構の構造基盤

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural Study of Human Dopamine D2 ReceptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医学のあゆみ-統合失調症の未来 ─研究と治療2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A2A receptor2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ligand complex structures of L-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Frontiers in the Structural Biology of GPCRs2023

Author(s)

Organizer

Data Source

[Presentation] 新規抗ヒスタミン薬の分子設計を目指したヒスタミンH4受容体の構造基盤2023

Author(s)

Organizer

Data Source

[Presentation] Structural insights into antipsychotics binding modes in dopamine D2-class receptors2018

Author(s)

Organizer

Data Source

[Presentation] A first novel GPCR structure determined at SACLA2017

Author(s)

Organizer

Data Source

Im Dohyun 林到ヒョン