Yagishita Shou 柳下祥

… Alternative Names

Yagishita Sho 柳下祥

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Researcher Number	50721940
Other IDs	https://orcid.org/0000-0003-2854-773X
Affiliation (Current)	2024: 東京大学, 大学院医学系研究科(医学部), 講師
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京大学, 大学院医学系研究科(医学部), 講師 2016 – 2017: 東京大学, 大学院医学系研究科(医学部), 助教 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Basic Section 46030:Function of nervous system-related / Transformative Research Areas, Section (I) / Neurophysiology / General neuroscience Except Principal Investigator Medium-sized Section 46:Neuroscience and related fields / Broad Section G / Complex systems
Keywords	Principal Investigator スパイン / スパイン形態可塑性 / ケイジドグルタミン酸 / 前頭葉 / ドーパミン / シナプス新生 / 可塑性 / 新皮質 / PFC / ノルアドレナリン … More / ミクログリア / トラウマ・モデル / EEG / 超高磁場MRI / マウスMRI / 聴覚予測 / PTSD / 聴覚系 / 皮質脳波 / 消去 / 聴覚予測課題 / トラウマ / 性差 / 個体差 / 統合失調症 / ２光子アンケージング / 形態可塑性 / 樹状突起スパイン / 報酬学習 / 光遺伝学 / 側坐核 / 条件づけ学習 … More Except Principal Investigator スパイン / メカノバイオロジー / 学習 / シナプス / 学習・記憶 / 神経回路 / 知能 / 情動 / 学習記憶 / アクチン繊維 / 作業記憶 / 記憶 / 樹状突起スパイン / 精神疾患 / 思春期 / 主体価値 / 潜在的・顕在的固体内動因 / 社会脳機能 / 親子関係 / 安静時脳活動 / 多変量解析 / 東京ティーンコホート / 長期的価値 / 思春期発達 / 潜在的・顕在的個体内動因 / 価値記憶 / 長期的な行動選択 Less

Developmental transition of spinogenesis and spine plasticity in the neorcortexPrincipal Investigator
- Principal Investigator
  
  柳下祥
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  The University of Tokyo
Neuronal mechanisms for subjectification ("tojisha-ka") processPrincipal Investigator
- Principal Investigator
  
  柳下祥
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (I)
- Research Institution
  The University of Tokyo
前頭前野スパイン・シナプスの可塑性を制御する新規シグナル路の解析Principal Investigator
- Principal Investigator
  
  柳下祥
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
From the structure-function relationship of dendrtic spines to synaptic mechanobiology
- Principal Investigator
  
  河西春郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  The University of Tokyo
From structural plasticity of dendritic spines to synaptic mechano-biology
- Principal Investigator
  
  河西春郎
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  The University of Tokyo
Analysis of spine plasticity in prefrontal cortex using 2-photon microscopyPrincipal Investigator
- Principal Investigator
  
  Yagishita Sho
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  The University of Tokyo
Neural mechanisms of personalized value
- Principal Investigator
  
  Tanaka Saori
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Advanced Telecommunications Research Institute International
Synaptic basis of conditioned learningPrincipal Investigator
- Principal Investigator
  
  Yagishita Sho
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Cellular bases for reward-related dopamine actions2023
- Author(s)
  Yagishita Sho
- Journal Title
  
  Neuroscience Research
  
  Volume: 188 Pages: 1-9
- DOI
  10.1016/j.neures.2022.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21H05176, KAKENHI-PROJECT-21H02594
[Journal Article] A behavioural correlate of the synaptic eligibility trace in the nucleus accumbens2022
- Author(s)
  Yamaguchi Kenji、Maeda Yoshitomo、Sawada Takeshi、Iino Yusuke、Tajiri Mio、Nakazato Ryosuke、Ishii Shin、Kasai Haruo、Yagishita Sho
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1921-1921
- DOI
  10.1038/s41598-022-05637-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21H02594, KAKENHI-PROJECT-20J00904
[Journal Article] Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis2021
- Author(s)
  Ucar Hasan、Watanabe Satoshi、Noguchi Jun、Morimoto Yuichi、Iino Yusuke、Yagishita Sho、Takahashi Noriko、Kasai Haruo
- Journal Title
  
  Nature
  
  Volume: 600 Issue: 7890 Pages: 686-689
- DOI
  10.1038/s41586-021-04125-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05176, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21H02594, KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-21K15203
[Journal Article] The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal.2021
- Author(s)
  Urakubo H, Yagishita S, Kasai H, Kubota Y, Ishii S
- Journal Title
  
  PLoS Comput Biol
  
  Volume: 17 Issue: 9 Pages: e1009364-e1009364
- DOI
  10.1371/journal.pcbi.1009364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03336, KAKENHI-PUBLICLY-21H00217, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-20K12062, KAKENHI-PLANNED-17H06310, KAKENHI-PLANNED-17H06311
[Journal Article] Spine dynamics in the brain, mental disorders and artificial neural networks2021
- Author(s)
  Kasai Haruo、Ziv Noam E.、Okazaki Hitoshi、Yagishita Sho、Toyoizumi Taro
- Journal Title
  
  Nature Reviews Neuroscience
  
  Volume: 22 Issue: 7 Pages: 407-422
- DOI
  10.1038/s41583-021-00467-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05432, KAKENHI-PROJECT-20H05685
[Journal Article] Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity2020
- Author(s)
  Hidetoshi Urakubo, Sho Yagishita, Haruo Kasai, Shin Ishii
- Journal Title
  
  PLoS Computational Biology
  
  Volume: 16 Issue: 7 Pages: 1008078-1008078
- DOI
  10.1371/journal.pcbi.1008078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12062, KAKENHI-PLANNED-17H06310, KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-17K00404, KAKENHI-PROJECT-19K16249, KAKENHI-PLANNED-16H06396
[Journal Article] Dopamine D2 receptors in discrimination learning and spine enlargement2020
- Author(s)
  Iino Yusuke、Sawada Takeshi、Yamaguchi Kenji、Tajiri Mio、Ishii Shin、Kasai Haruo、Yagishita Sho
- Journal Title
  
  Nature
  
  Volume: 579 Issue: 7800 Pages: 555-560
- DOI
  10.1038/s41586-020-2115-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-16H06396, KAKENHI-PROJECT-18J21753, KAKENHI-PROJECT-18J21845, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-19K16249
[Journal Article] Computational Characteristics of the Striatal Dopamine System Described by Reinforcement Learning With Fast Generalization2020
- Author(s)
  Fujita Yoshihisa、Yagishita Sho、Kasai Haruo、Ishii Shin
- Journal Title
  
  Frontiers in Computational Neuroscience
  
  Volume: 14 Pages: 66-66
- DOI
  10.3389/fncom.2020.00066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00480, KAKENHI-PROJECT-19K16249, KAKENHI-PLANNED-16H06396
[Journal Article] Transient and sustained effects of dopamine and serotonin signaling in motivation‐related behavior2019
- Author(s)
  Yagishita Sho
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 74 Issue: 2 Pages: 91-98
- DOI
  10.1111/pcn.12942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16249, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-16H06396
[Journal Article] Calcineurin knockout mice show a selective loss of small spines2018
- Author(s)
  Okazaki H, Hayashi-Takagi A, Nagaoka A, Negishi M, Ucar H, Yagishita S, Ishii K, Toyoizumi T, Kasai H
- Journal Title
  
  Neuroscience Letters
  
  Volume: 671 Pages: 99-102
- DOI
  10.1016/j.neulet.2018.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293260, KAKENHI-PUBLICLY-17H05735, KAKENHI-PLANNED-18H05433, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-17K19438, KAKENHI-PLANNED-16H06396
[Journal Article] In Vivo Volume Dynamics of Dendritic Spines in the Neocortex of Wild-Type and Fmr1 KO Mice.2018
- Author(s)
  Ishii K, Nagaoka A, Kishida Y, Okazaki H, Yagishita S, Ucar H, Takahashi N, Saito N, Kasai H.
- Journal Title
  
  eNeuro
  
  Volume: 5 Issue: 5 Pages: 1-13
- DOI
  10.1523/eneuro.0282-18.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08530, KAKENHI-PROJECT-26221001, KAKENHI-PLANNED-16H06396
[Presentation] D2受容体機能障害と社会環境相互作用による新しい統合失調症発症モデル2022
- Author(s)
  柳下祥
- Organizer
  精神神経学会
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] Dopaminergic modulation of synaptic plasticity in generalization and discrimination learning2022
- Author(s)
  Sho Yagishita
- Organizer
  Computational Approaches to Memory and Plasticity Bangalore India
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS.2022
- Author(s)
  Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., Takahashi, N., Kasai, H.
- Organizer
  JNS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05685
[Presentation] Dopaminergic modulation of synaptic plasticity in generalization and discrimination learning2022
- Author(s)
  Sho Yagishita
- Organizer
  Computational Approaches to Memory and Plasticity Bangalore India
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] ドーパミン系ストレス負荷による新規統合失調症の発症モデル2022
- Author(s)
  柳下祥
- Organizer
  第44回日本生物学的精神医学会年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] D2受容体機能障害と社会環境相互作用による新しい統合失調症発症モデル2022
- Author(s)
  柳下祥
- Organizer
  精神神経学会
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] ドーパミン系ストレス負荷による新規統合失調症の発症モデル2022
- Author(s)
  柳下祥
- Organizer
  ,第44回日本生物学的精神医学会年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] Disinhibitory gating of discrimination learning and spine enlargement by dopamine D2 receptors in the nucleus accumbens2021
- Author(s)
  Sho Yagishita
- Organizer
  SWEBAGS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] ドーパミンによるシナプス可塑性と汎化弁別学習の制御2021
- Author(s)
  柳下　祥
- Organizer
  ドーパミン研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] 小集団脳科学と大集団脳科学の相互トランスレーショナル科学への展2021
- Author(s)
  柳下　祥
- Organizer
  日本発達神経科学会第10回学術集
- Invited
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] Dopaminergic modulation of synaptic plasticity in learning and psychiatric disorders2021
- Author(s)
  Sho Yagishita
- Organizer
  CBS Summer seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] Disinhibitory gating of discrimination learning and spine enlargement by dopamine D2 receptors in the nucleus accumbens2021
- Author(s)
  Sho Yagishita
- Organizer
  SWEBAGS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] Dopaminergic modulation of synaptic plasticity in learning and psychiatric disorders2021
- Author(s)
  Sho Yagishita
- Organizer
  CBS Summer seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] 動物モデルにおける壁～身体医学の生物医学と精神医学の基礎科学の相違～2021
- Author(s)
  柳下　祥
- Organizer
  精神神経科学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] 動物モデルにおける壁～身体医学の生物医学と精神医学の基礎科学の相違～2021
- Author(s)
  柳下　祥
- Organizer
  精神神経科学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] ドーパミンによるシナプス可塑性と汎化弁別学習の制御2021
- Author(s)
  柳下　祥
- Organizer
  ドーパミン研究会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05176
[Presentation] 小集団脳科学と大集団脳科学の相互トランスレーショナル科学への展2021
- Author(s)
  柳下　祥
- Organizer
  日本発達神経科学会第10回学術集
- Invited
- Data Source
  KAKENHI-PROJECT-21H02594
[Presentation] Disinhibitory gating of discrimination learning and spine enlargement by dopamine D2 receptors in the nucleus accumbens2020
- Author(s)
  Sho Yagishita
- Organizer
  Virtual Dopamine Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] Potentiation of presynaptic functions by mechanosensing the spine enlargement in rat hippocampus.2020
- Author(s)
  Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., , Morimoto, Y., Takahashi, N., Kasai, H.
- Organizer
  FENS (Glasgow online).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05685
[Presentation] Disinhibitory gating of discrimination learning and spine enlargement by dopamine D2 receptors in the nucleus accumbens2019
- Author(s)
  Yagishita, S.
- Organizer
  NIPS Learning & Memory meeting
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] Neural basis of motivation and depression2018
- Author(s)
  柳下　祥
- Organizer
  日本精神神経学会
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] A super-sensitivity of dopamine D2 receptor signaling for structural plasticity of dendritic spines.2017
- Author(s)
  Yagishita, S., Iino, Y., Nakazato, R., and Kasai, H.
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] Synaptic basis of reinforcement learning2017
- Author(s)
  Yagishita, S
- Organizer
  2nd Annual meeting of Nepalese Neuroscience Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] Dopamine actions on dendritic spines in the nucleus accumbens for reward-related learning2017
- Author(s)
  Yagishita, S
- Organizer
  Naito Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06396
[Presentation] 脳機能の構成的理解に基づく統合失調症研究の可能性2016
- Author(s)
  柳下　祥
- Organizer
  統合失調症学会
- Place of Presentation
  ベイシア文化ホール（群馬県前橋市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K18333
[Presentation] モノアミン作用の機能的理解を起点とした基礎から臨床研究への発展の道筋2016
- Author(s)
  柳下　祥
- Organizer
  生物精神学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K18333

1. 河西春郎 (60224375)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. UCAR HASAN (50748423)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Tanaka Saori (00505985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 橋本龍一郎 (00585838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中村優子 (00610023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中谷裕教 (30333868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 多田真理子 (70758193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 植松朗 (90716242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 川村猛 (70306835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MAEDA Yoshitomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAZATO Ryosuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 笠井清登

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 浦久保秀俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 林朗子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 窪田芳之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 豊泉太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 高橋倫子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yagishita Shou 柳下 祥

Yagishita Sho 柳下 祥

Research Projects

Research Products

Co-Researchers

Developmental transition of spinogenesis and spine plasticity in the neorcortexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuronal mechanisms for subjectification ("tojisha-ka") processPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

前頭前野スパイン・シナプスの可塑性を制御する新規シグナル路の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From the structure-function relationship of dendrtic spines to synaptic mechanobiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From structural plasticity of dendritic spines to synaptic mechano-biology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of spine plasticity in prefrontal cortex using 2-photon microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neural mechanisms of personalized value

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synaptic basis of conditioned learningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cellular bases for reward-related dopamine actions2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A behavioural correlate of the synaptic eligibility trace in the nucleus accumbens2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spine dynamics in the brain, mental disorders and artificial neural networks2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity2020

Author(s)

Yagishita Shou 柳下祥

Yagishita Sho 柳下祥