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Okazaki Tomohiko  岡崎 朋彦

ORCIDConnect your ORCID iD *help
Researcher Number 50724598
Other IDs
Affiliation (Current) 2025: 北海道大学, 遺伝子病制御研究所, 准教授
Affiliation (based on the past Project Information) *help 2024: 北海道大学, 遺伝子病制御研究所, 准教授
2020 – 2022: 北海道大学, 遺伝子病制御研究所, 准教授
2017 – 2019: 東京大学, 大学院薬学系研究科(薬学部), 助教
2016: 東京大学, 大学院薬学系研究科(薬学部), 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Immunology
Keywords
Principal Investigator
アポトーシス / インターフェロン / 翻訳後修飾 / 膜タンパク質 / ウイルス / I型インターフェロン / Gla化 / ウイルス感染 / ウイルス感染症 / 免疫学 / カルボキシル化 / 細胞死
  • Research Projects

    (5 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (2 People)
  •  ストレスシグナルを仲介する新たな翻訳後修飾機構の発見と応用Principal Investigator

    • Principal Investigator
      岡崎 朋彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Hokkaido University
  •  ストレス応答戦略における膜トポロジー制御の包括的理解Principal Investigator

    • Principal Investigator
      岡崎 朋彦
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Hokkaido University
  •  翻訳後修飾を介した抗ウイルス応答の選別機構の解析Principal Investigator

    • Principal Investigator
      岡崎 朋彦
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Hokkaido University
  •  Differential control of the interefon and apoptotic responses against viral infectionPrincipal Investigator

    • Principal Investigator
      Okazaki Tomohiko
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Hokkaido University
      The University of Tokyo
  •  Differential regulation of the antiviral responsesPrincipal Investigator

    • Principal Investigator
      Okazaki Tomohiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

  • [Book] 生命誌 -ゆらぐ-2017

    • Author(s)
      岡崎朋彦
    • Total Pages
      3
    • Publisher
      生命誌ジャーナル
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Book] 臨床免疫・アレルギー科2017

    • Author(s)
      青山幸恵子、後藤由季子、岡崎朋彦
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Journal Article] Control of mitochondrial dynamics and apoptotic pathways by peroxisomes2022

    • Author(s)
      Jiang Chenxing、Okazaki Tomohiko
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 10 Pages: 1-9

    • DOI

      10.3389/fcell.2022.938177

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07064, KAKENHI-PROJECT-22H04926
  • [Journal Article] NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense2020

    • Author(s)
      Saeko Aoyama-Ishiwatari, Tomohiko Okazaki, Shun-ichiro Iemura, Tohru Natsume, Yasushi Okada, Yukiko Gotoh
    • Journal Title

      The Journal of Immunology

      Volume: 206 Issue: 1 Pages: 154-163

    • DOI

      10.4049/jimmunol.2000306

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18K07168, KAKENHI-PLANNED-16H06481, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795, KAKENHI-PROJECT-19H03394, KAKENHI-PROJECT-21K07064
  • [Journal Article] ASK family in infection and inflammatory disease2017

    • Author(s)
      Tomohiko Okazaki
    • Journal Title

      Advances in Biological Regulation

      Volume: 66 Pages: 37-45

    • DOI

      10.1016/j.jbior.2017.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] 翻訳後修飾を介した抗ウイルス防御機構の理解と応用2022

    • Author(s)
      岡崎朋彦
    • Organizer
      令和3年度「感染・免疫・がん・炎症」全国共同研究拠点シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07064
  • [Presentation] Antiviral defense mechanism via vitamin K-mediated cytoplasmic protein carboxylation2022

    • Author(s)
      Okazaki Tomohiko
    • Organizer
      Gene Expression and Signaling in the Immune System Meeting, Cold Spring Harbor
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07064
  • [Presentation] 翻訳後修飾を介した抗ウイルス防御機構の理解と応用2022

    • Author(s)
      岡崎朋彦
    • Organizer
      令和3年度「感染・免疫・がん・炎症」全国共同研究拠点シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] 脳内ウイルス感染に対するIFN産生とアポトーシスの選択2021

    • Author(s)
      齋藤里歩、岡崎朋彦
    • Organizer
      第七回北海道大学部局横断シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07064
  • [Presentation] Selective regulation of type I interferon and apoptosis and its relevance to brain protection against viral infection2021

    • Author(s)
      Tomohiko Okazaki
    • Organizer
      KEY FORUM 2021 International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] ウイルス感染細胞におけるアポトーシスとインターフェロン産生の使い分け戦略2021

    • Author(s)
      岡崎朋彦
    • Organizer
      千里ライフサイエンスセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] Roles of embryonic microglia in Autism-like behaviors induced by maternal immune activation2021

    • Author(s)
      岡崎朋彦
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] Selective regulation of type I interferon and apoptosis and its relevance to brain protection against viral infection2021

    • Author(s)
      Tomohiko Okazaki
    • Organizer
      KEY FORUM 2021 International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07064
  • [Presentation] Roles of embryonic microglia in Autism-like behaviors induced by maternal immune activation2021

    • Author(s)
      岡崎朋彦
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K07064
  • [Presentation] 脳内ウイルス感染に対するIFN産生とアポトーシスの選択2021

    • Author(s)
      齋藤里歩、岡崎朋彦
    • Organizer
      第七回北海道大学部局横断シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] First line defense mechanisms against viral infection2020

    • Author(s)
      Tomohiko Okazaki, Yukiko Gotoh
    • Organizer
      AMED-CREST International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] A division of labour for the type Ⅰ Interferon and apoptosis induction after viral infection2019

    • Author(s)
      Tomohiko Okazaki, Moe Inoue, Shinpei Toyoda, Yukiko Gotoh
    • Organizer
      17th International Congress of Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07168
  • [Presentation] A division of labour for the type Ⅰ interferon and apoptosis induction after viral infection2018

    • Author(s)
      岡崎朋彦、井上萌、後藤由季子
    • Organizer
      TOLL2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] A division of labour for the type Ⅰ interferon and apoptosis induction after viral infection2018

    • Author(s)
      岡崎朋彦、井上萌、後藤由季子
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] Differential control of interferon and apoptotic responses to viral infection2017

    • Author(s)
      Tomohiko Okazaki
    • Organizer
      The 4th symposium of Max Planck-The University of Tokyo Center for Integrative Inflammology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] ビタミンK依存性カルボキシラーゼGGCXによる脳内ウイルス感染時の恒常性維持機構の解析2017

    • Author(s)
      岡崎朋彦、後藤由季子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] Vitamin K-dependent γ-glutamyl carboxylase (GGCX) switches MAVS-mediated immune responses and protects against viral infection of the central nervous system2017

    • Author(s)
      Tomohiko Okazaki, Yukiko Gotoh
    • Organizer
      Cell Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] Modulation of the antiviral adaptor IPS-1-mediated innate immune responses by carboxylation2016

    • Author(s)
      岡崎朋彦、武地佳菜、後藤由季子
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      イタリア
    • Year and Date
      2016-06-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19149
  • [Presentation] Modulation of the antiviral adaptor IPS-1-mediated innate immune responses by carboxylation2016

    • Author(s)
      岡崎朋彦、武地佳菜、後藤由季子
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16K19149
  • 1.  GOTOH Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  佐々木 泰史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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