YOKOTA Shigefumi 横田繁史

Researcher Number	50725281
Affiliation (based on the past Project Information) *help	2017: 独立行政法人国立病院機構(京都医療センター臨床研究センター), 内分泌代謝高血圧研究部, 研究員 2016: 生理学研究所, 生体機能調節研究領域, NIPSリサーチフェロー
Review Section/Research Field	Principal Investigator Metabolomics Except Principal Investigator Metabolomics
Keywords	Principal Investigator 臓器関連間 / レプチン / マイオカイン / インスリン依存性糖尿病 / leptin / myonectin / IL-6 / myokine / 臓器連関 / streptozotocin / AMPK … More Except Principal Investigator … More Myokine / 1型糖尿病 / ストレプトゾトシン / leptin / myokine / streptozotocin / AMPK Less

The metabolic effect and pathophysiological role of skeletal muscle AMPK in streptozocin-induced diabetic micePrincipal Investigator
- Principal Investigator
  
  Yokota Shigefumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
  National Institute for Physiological Sciences
Study of muscle AMPK-dependent factors that improve metabolic abnormalities in strepotozocin-induced diabetes
- Principal Investigator
  
  MINOKOSHI Yasuhiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  National Institute for Physiological Sciences

All 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.2018
- Author(s)
  Okamoto S, Sato T, Tateyama M, Kageyama H, Maejima Y, Nakata M, Hirako S, Matsuo T, Kyaw S, Shiuchi T, Toda C, Sedbazar U, Saito K, Asgar NF, Zhang B, Yokota S, Kobayashi K, Foufelle F, Ferré P, Nakazato M, Masuzaki H, Shioda S, Yada T, Kahn BB, Minokoshi Y.
- Journal Title
  
  Cell Rep.
  
  Volume: 22 Issue: 3 Pages: 706-721
- DOI
  10.1016/j.celrep.2017.11.102
- NAID
  120007001417
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09442, KAKENHI-PROJECT-17K00933, KAKENHI-PROJECT-17K08557, KAKENHI-PROJECT-15K09405, KAKENHI-PROJECT-16K13030, KAKENHI-PROJECT-15K16217, KAKENHI-PROJECT-16K19549, KAKENHI-PROJECT-18K19551, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-17H04203, KAKENHI-PROJECT-17K09839, KAKENHI-PROJECT-20K20392, KAKENHI-PROJECT-17H05059
[Journal Article] Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues.2017
- Author(s)
  Coutinho EA, Okamoto S, Ishikawa AW, Yokota S, Wada N, Hirabayashi T, Saito K, Sato T, Takagi K, Wang CC, Kobayashi K, Ogawa Y, Shioda S, Yoshimura Y, Minokoshi Y
- Journal Title
  
  Diabetes
  
  Volume: 66 Issue: 9 Pages: 2372-2372
- DOI
  10.2337/db16-1344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11597, KAKENHI-PROJECT-17K14942, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-17H04203, KAKENHI-PROJECT-15K18351, KAKENHI-PROJECT-16K19549
[Journal Article] Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.2015
- Author(s)
  Tang L, Okamoto S, Shiuchi T, Toda C, Takagi K, Sato T, Saito K, Yokota S, Minokoshi Y.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 10 Pages: 3680-3694
- DOI
  10.1210/en.2015-1096
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15352
[Presentation] 肥満症患者の糖代謝機能・骨格筋量制御における筋肉由来液性因子・myostatinの病態意義2018
- Author(s)
  横田繁史,増田慎也、田中将志、山陰一、村中和哉、井上隆之、北野隆司、真田樹義、石井好二郎、日下部徹、島津章、浅原哲子
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-16K19549
[Presentation] Involvement of myokines in metabolic abnormalities of stretozocin-induced diabetes.2017
- Author(s)
  Shigefumi Yokota, Yasuhiko Minokoshi
- Organizer
  The 94th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Actocity Hamamatsu, Hamamatsu, Shizuoka
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K15352
[Presentation] Role of myokines in metabolic abnormalities of streptozotocin-induced diabetes.2017
- Author(s)
  横田繁史, 箕越靖彦
- Organizer
  第91回日本生理学会
- Place of Presentation
  静岡県浜松市アクトシティホール
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16K19549
[Presentation] ストレプトゾトシン糖尿病の代謝異常に及ぼす骨格筋AMPKの調節作用2016
- Author(s)
  横田繁史、箕越靖彦
- Organizer
  生理学研究所研究会
- Place of Presentation
  生理学研究所、岡崎、愛知
- Year and Date
  2016-09-10
- Data Source
  KAKENHI-PROJECT-15K15352
[Presentation] Role of myokines in metabolic abnormalities of streptozotocin-induced diabetes.2016
- Author(s)
  横田繁史, 箕越靖彦
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京都千代田区東京ファッションタウン
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K19549
[Presentation] ストレプトゾトシン誘導型糖尿病の代謝異常に及ぼすマイオカインの調節作用2016
- Author(s)
  横田繁史、箕越靖彦
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン、江東区、東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K15352
[Presentation] ストレプトゾトシン（STZ）糖尿病による骨格筋および白色脂肪組織の委縮を引き起こすメカニズム2015
- Author(s)
  横田繁史、岡本士毅、箕越靖彦
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K15352

1. MINOKOSHI Yasuhiko (10200099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. OKAMOTO Shiki (40342919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. SAITO Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 平林敬浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中田正範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOTA Shigefumi 横田 繁史

Research Projects

Research Products

Co-Researchers

The metabolic effect and pathophysiological role of skeletal muscle AMPK in streptozocin-induced diabetic micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of muscle AMPK-dependent factors that improve metabolic abnormalities in strepotozocin-induced diabetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肥満症患者の糖代謝機能・骨格筋量制御における筋肉由来液性因子・myostatinの病態意義2018

Author(s)

Organizer

Data Source

[Presentation] Involvement of myokines in metabolic abnormalities of stretozocin-induced diabetes.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Role of myokines in metabolic abnormalities of streptozotocin-induced diabetes.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ストレプトゾトシン糖尿病の代謝異常に及ぼす骨格筋AMPKの調節作用2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Role of myokines in metabolic abnormalities of streptozotocin-induced diabetes.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ストレプトゾトシン誘導型糖尿病の代謝異常に及ぼすマイオカインの調節作用2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ストレプトゾトシン（STZ）糖尿病による骨格筋および白色脂肪組織の委縮を引き起こすメカニズム2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

YOKOTA Shigefumi 横田繁史