Kano Gen 加納原

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Gen Kano 加納原

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Researcher Number	50725306
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 特任講師 2020: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 2015 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords	Principal Investigator Siglec-8 / Neu5Gc / 腸管オルガノイド / シアル酸 / 炎症性腸疾患 / 好酸球 / Sigle-8 / Proximity ligation assay / リン酸化 / 細胞内局在 … More / Src family kinase / NOXサブユニット / 細胞内ROS産生機構 / Siglec誘導性細胞死 / NOX2サブユニット / gp91phox / p40phox / mitochondria / ROS / Siglec-9 / eosinophil / neutrophil / Cell death / Siglec Less

Research Projects
(2 results)
Research Products
(6 results)

Unraveling the role of eosinophils in inflammatory bowel diseases using human enteroidsPrincipal Investigator
- Principal Investigator
  
  Gen Kano
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular mechanism and clinical implications of Sigle-9 induced cell death of activated neutrophils.Principal Investigator
- Principal Investigator
  
  Kano Gen
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine

All 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Identification of reactive oxygen production site in Siglec-8 induced eosinophil death2019
- Author(s)
  Toshihiro Tomii, Gen Kano
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 143 Issue: 2 Pages: AB290-AB290
- DOI
  10.1016/j.jaci.2018.12.888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09661
[Journal Article] Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases.2016
- Author(s)
  Gen Kano, Bruce B Bochner and Nives Zimmermann
- Journal Title
  
  Immunobiology
  
  Volume: 222 Issue: 2 Pages: 343-349
- DOI
  10.1016/j.imbio.2016.09.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09661
[Journal Article] Whole-exome sequencing identification of novel DNAH5 mutations in a young patient with primary ciliary dyskinesia.2016
- Author(s)
  Gen Kano, Hisashi Tsujii, Kazuhiko Takeuchi, Kaname Nakatani, Makoto Ikejiri, Satoru Ogawa, Hisami Kubo, Mizuho Nagao, and Takao Fujisawa
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 14 Issue: 6 Pages: 5077-5083
- DOI
  10.3892/mmr.2016.5871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09661, KAKENHI-PROJECT-16K11210
[Presentation] Identification of reactive oxygen production site in Siglec-8 induced eosinophil death2019
- Author(s)
  Toshihiro Tomii, Gen Kano
- Organizer
  2019 American Academy of Allergy, Asthma and Immunology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09661
[Presentation] Siglec-8誘導性細胞死における活性酸素産生部位の同定2018
- Author(s)
  冨井敏宏、加納原
- Organizer
  アレルギー・好酸球研究会2018
- Data Source
  KAKENHI-PROJECT-15K09661
[Presentation] Distinct Mode of Reactive Oxygen Species Generation in Eosinophil Cell Death Induced by Siglec-8/IL-5 Co-stimulation and Extracellular DNA Trap Cell Death.2015
- Author(s)
  Gen Kano and Nives Zimmermann
- Organizer
  9th Biennial Symposium, International Eosinophil Society
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09661

Kano Gen 加納 原

Gen Kano 加納 原

Research Projects

Research Products

Unraveling the role of eosinophils in inflammatory bowel diseases using human enteroidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism and clinical implications of Sigle-9 induced cell death of activated neutrophils.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification of reactive oxygen production site in Siglec-8 induced eosinophil death2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-exome sequencing identification of novel DNAH5 mutations in a young patient with primary ciliary dyskinesia.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Identification of reactive oxygen production site in Siglec-8 induced eosinophil death2019

Author(s)

Organizer

Data Source

[Presentation] Siglec-8誘導性細胞死における活性酸素産生部位の同定2018

Author(s)

Organizer

Data Source

[Presentation] Distinct Mode of Reactive Oxygen Species Generation in Eosinophil Cell Death Induced by Siglec-8/IL-5 Co-stimulation and Extracellular DNA Trap Cell Death.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kano Gen 加納原

Gen Kano 加納原