Yamahara Kosuke 山原康佑

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YAMAHARA KOSUKE 山原康佑

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Researcher Number	50731915
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023: 滋賀医科大学, 医学部, 講師 2021 – 2022: 滋賀医科大学, 医学部, 助教 2020: 滋賀医科大学, 医学部, 特任助教 2018 – 2019: 滋賀医科大学, 医学部, 医員 2015: 滋賀医科大学, 医学部, 客員助教 2014: 滋賀医科大学, 医学部, 医員
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 寿命延長効果 / メチオニン代謝 / ポリアミン代謝 / カロリー制限 / 腎臓 / 糸球体上皮細胞 / 転写因子 / ポリアミン / MAFB / オートファジー … More / ポドサイト / 老化 / アミノ酸 / 栄養学 / 加齢 Less

メチオニン制限食による腎保護効果の臨床応用に向けてーポリアミン代謝に着目してーPrincipal Investigator
- Principal Investigator
  
  山原康佑
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shiga University of Medical Science
Regulation of autophagy in podocyte by the transcription factor MAFBPrincipal Investigator
- Principal Investigator
  
  Yamahara Kosuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shiga University of Medical Science
The effect of dietary amino acids balance for mouse organs under caloric restriction.Principal Investigator
- Principal Investigator
  
  YAMAHARA KOSUKE
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Shiga University of Medical Science

All 2020 2018 2016 2015

All Journal Article Presentation Book

[Book] 糖尿病性腎症克服に残された課題～挑戦　発症メカニズムに立脚した治療の将来展望2015
- Author(s)
  久米真司、安田真子、山原康佑
- Total Pages
  7
- Publisher
  月刊糖尿病
- Data Source
  KAKENHI-PROJECT-26893116
[Journal Article] A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier2020
- Author(s)
  Wei Liang, Kosuke Yamahara, Camila Hernando-Erhard, Simon Lagies, Nicola Wanner, Huan Liang, Christoph Schell, Bernd Kammerer, Tobias B.Huber7, Tillmann Bork
- Journal Title
  
  Kidney International
  
  Volume: 98 Issue: 6 Pages: 1434-1448
- DOI
  10.1016/j.kint.2020.06.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15999
[Journal Article] Impaired podocyte autophagy exacerbates proteinuria in diabetic nephropathy.2016
- Author(s)
  Tagawa A, Yasuda M, Kume S, Ymahara K, Nakazawa J, Chin-Kanasaki M, Araki H, Araki SI, Koya D, Asanuma K, Kim EH, Haneda M, Kajiwara N, Hayashi K, Ohashi H, Ugi S, Maegawa H, Uzu T
- Journal Title
  
  Diabetes.
  
  Volume: - Issue: 3 Pages: 755-767
- DOI
  10.2337/db15-0473
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670431, KAKENHI-PROJECT-15K19511, KAKENHI-PROJECT-26893116, KAKENHI-PROJECT-26293217, KAKENHI-PROJECT-25713033
[Journal Article] Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.2015
- Author(s)
  Yasuda-Yamahara M, Kume S, Yamahara K, Nakazawa J, Chin-Kanasaki M, Araki H, Araki S, Koya D, Haneda M, Ugi S, Maegawa H, Uzu T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 18 Issue: 2 Pages: 249-255
- DOI
  10.1016/j.bbrc.2015.08.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19511, KAKENHI-PROJECT-26893116, KAKENHI-PROJECT-26293217
[Presentation] Transcription factor MAFB is a new key regulator of podocyte autophagy2018
- Author(s)
  Kosuke Yamahara, Tillmann Bork, Wei Liang, Christoph Schell, Shinji Kume, Mamoru Yoshibayashi, Shin-ichi Araki, Hiroshi Maegawa, Tobias B. Huber.
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15999
[Presentation] 転写因子Mafbは糸球体上皮細胞のオートファジー活性を制御する2018
- Author(s)
  山原康佑、TillmannBork、WeiLiang、ChristophSchell、吉林護、久米真司、荒木信一、Tobias BHuber、前川聡
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15999

1. ASANUMA Katsuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 安田真子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamahara Kosuke 山原 康佑

YAMAHARA KOSUKE 山原 康佑

Research Projects

Research Products

Co-Researchers

メチオニン制限食による腎保護効果の臨床応用に向けてーポリアミン代謝に着目してーPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of autophagy in podocyte by the transcription factor MAFBPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of dietary amino acids balance for mouse organs under caloric restriction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 糖尿病性腎症克服に残された課題～挑戦 発症メカニズムに立脚した治療の将来展望2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired podocyte autophagy exacerbates proteinuria in diabetic nephropathy.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Transcription factor MAFB is a new key regulator of podocyte autophagy2018

Author(s)

Organizer

Data Source

[Presentation] 転写因子Mafbは糸球体上皮細胞のオートファジー活性を制御する2018

Author(s)

Organizer

Data Source

Yamahara Kosuke 山原康佑

YAMAHARA KOSUKE 山原康佑

[Book] 糖尿病性腎症克服に残された課題～挑戦　発症メカニズムに立脚した治療の将来展望2015