Sakurai Yasutaka 櫻井靖高

Researcher Number	50733101
Other IDs	https://orcid.org/0000-0002-7966-1295
Affiliation (Current)	2025: 北里大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2015 – 2024: 北里大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Risk sciences of radiation and chemicals Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 49030:Experimental pathology-related / Risk sciences of radiation and chemicals
Keywords	Principal Investigator REV7 / 突然変異 / DNA損傷トレランス / 発癌 / 紫外線 / DNAポリメラーゼ / 損傷乗り越えDNA合成 / 近接依存性ビオチン標識 / 薬剤抵抗性 / PARP阻害剤 … More / 二本鎖切断修復 / 変異 / DNA複製 / DNA修復 / 細胞死 / 薬剤耐性 … More Except Principal Investigator REV7 / 治療効果 / 胃癌 / 精子形成 / REV7コンディショナルノックアウトマウス / 結合蛋白 / プロモーター解析 / 遺伝子発現 / 精子形成不全 / マイクロアレイ解析 / 生殖細胞 / 精巣 / コンディショナルノックアウトマウス / 精原幹細胞 / 配偶子形成 / 紫外線誘発皮膚発癌 / 損傷乗り越え型DNA複製 / 病理学 / 紫外線 / DNA損傷 / 遺伝子 / 応用動物 / 癌 / REV7ノックダウン / Rev7コンディショナルノックアウトマウス / Rev7トランスジェニックマウス / 悪性黒色腫 / 遺伝子改変マウス / 紫外線誘発皮膚癌 / 損傷乗り越えDNA複製 Less

新規DNA二本鎖切断修復関連タンパク質によるPARP阻害剤抵抗性メカニズムの解明Principal Investigator
- Principal Investigator
  
  櫻井靖高
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
術前化学療法進行胃癌に対する治療効果とDNA修復関連蛋白REV7の発現との関連
- Principal Investigator
  
  一戸昌明
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kitasato University
DNA損傷トレランスタンパク質REV7を介した紫外線誘発皮膚癌の発生機序の解明Principal Investigator
- Principal Investigator
  
  櫻井靖高
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
Elucidation of the function of DNA damage tolerance in UV-induced skin cancer developmentPrincipal Investigator
- Principal Investigator
  
  Sakurai Yasutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
Elucidation of novel molecular mechanisms for maintenance of spermatogonial stem cells and gametogenesis in the testis
- Principal Investigator
  
  Murakumo Yoshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
A study on DNA damage tolerance pathways as novel targets for cancer therapyPrincipal Investigator
- Principal Investigator
  
  Sakurai Yasutaka
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kitasato University
Involvement of translesion DNA synthesis in the development of UV-induced skin cancer and its possible mechanisms
- Principal Investigator
  
  Murakumo Yoshiki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kitasato University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] REV7 is involved in outcomes of platinum-based chemotherapy in pancreatic cancer via controlling the DNA damage response2024
- Author(s)
  Akihiro Tamaki, Takuya Kato, Yasutaka Sakurai, Keita Sato, Kai Adachi, Masayoshi Tadehara, Taro Kogami, Masahiro Matsushita, Akiyoshi Hoshino, Itaru Sanoyama, Yoshiko Numata, Atsuko Umezawa, Masaaki Ichinoe, Masatoshi Ichihara, Chika Kusano, Yoshiki Murakumo
- Journal Title
  
  Cancer Science
  
  Volume: Volume115, Issue2 Issue: 2 Pages: 660-671
- DOI
  10.1111/cas.16044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15414, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-23K06486, KAKENHI-PROJECT-23K08306
[Journal Article] REV7 in Cancer Biology and Management2023
- Author(s)
  Yoshiki Murakumo, Yasutaka Sakurai, Takuya Kato, Hiroshi Hashimoto, Masaaki Ichinoe
- Journal Title
  
  Cancers (Basel) .
  
  Volume: 15 Issue: 6 Pages: 1-15
- DOI
  10.3390/cancers15061721
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-20K07449, KAKENHI-PROJECT-20K07450
[Journal Article] Identification of the promoter region regulating the transcription of the REV7 gene2023
- Author(s)
  Shimada Yuko、Kato Takuya、Sakurai Yasutaka、Watanabe Hitoe、Nonaka Mayu、Nanaura Natsumi、Ichinoe Masaaki、Murakumo Yoshiki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 662 Pages: 8-17
- DOI
  10.1016/j.bbrc.2023.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-23K08306
[Journal Article] Clinicopathological Significance of BRCAness in Resectable Pancreatic Ductal Adenocarcinoma and Its Association With Anticancer Drug Sensitivity in Pancreatic Cancer Cells2022
- Author(s)
  Tadehara Masayoshi、Kato Takuya、Adachi Kai、Tamaki Akihiro、Kesen Yurika、Sakurai Yasutaka、Ichinoe Masaaki、Koizumi Wasaburo、Murakumo Yoshiki
- Journal Title
  
  Pancreas
  
  Volume: 51 Issue: 2 Pages: 183-189
- DOI
  10.1097/mpa.0000000000001975
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973
[Journal Article] CD109 expression in tumor cells and stroma correlates with progression and prognosis in pancreatic cancer2021
- Author(s)
  Adachi Kai、Sakurai Yasutaka、Ichinoe Masaaki、Tadehara Masayoshi、Tamaki Akihiro、Kesen Yurika、Kato Takuya、Mii Shinji、Enomoto Atsushi、Takahashi Masahide、Koizumi Wasaburo、Murakumo Yoshiki
- Journal Title
  
  Virchows Archiv
  
  Volume: - Issue: 4 Pages: 819-829
- DOI
  10.1007/s00428-021-03230-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-22K07000
[Journal Article] Upregulation of REV7 correlates with progression of malignant melanoma2021
- Author(s)
  Hoshino Akiyoshi、Nakayama Chika、Jiang Shi‐Xu、Sakurai Yasutaka、Kato Takuya、Numata Yoshiko、Umezawa Atsuko、Ichinoe Masaaki、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 72 Issue: 1 Pages: 14-24
- DOI
  10.1111/pin.13174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-20K07449
[Journal Article] Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation2020
- Author(s)
  Sanoyama Itaru、Sakurai Yasutaka、Ichinoe Masaaki、Hoshino Akiyoshi、Kesen Yurika、Kato Takuya、Numata Yoshiko、Umezawa Atsuko、Jiang Shi‐Xu、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 71 Issue: 1 Pages: 15-23
- DOI
  10.1111/pin.13040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07450, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] Expression of CA2 and CA9 carbonic anhydrases in ulcerative colitis and ulcerative colitis‐associated colorectal cancer2020
- Author(s)
  Nakada Norihiro、Mikami Tetuo、Horie Kayo、Nagashio Ryo、Sakurai Yasutaka、Sanoyama Itaru、Yoshida Tsutomu、Sada Miwa、Kobayashi Kiyonori、Sato Yuichi、Okayasu Isao、Murakumo Yoshiki
- Journal Title
  
  Pathology International
  
  Volume: 70 Issue: 8 Pages: 523-532
- DOI
  10.1111/pin.12949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07026, KAKENHI-PROJECT-19K07738, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] Inactivation of REV7 enhances chemosensitivity and overcomes acquired chemoresistance in testicular germ cell tumors.2020
- Author(s)
  Sakurai Y, Ichinoe M, Yoshida K, Nakazato Y, Saito S, Satoh M, Nakada N, Sanoyama I, Umezawa A, Numata Y, Shi-Xu J, Ichihara M, Takahashi M, Murakumo Y
- Journal Title
  
  Cancer Lett.
  
  Volume: 489 Pages: 100-110
- DOI
  10.1016/j.canlet.2020.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09011, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] CD109, a negative regulator of TGF-β signaling, is a putative risk marker in diffuse large B-cell lymphoma.2017
- Author(s)
  Yokoyama M, Ichinoe M, Okina S, Sakurai Y, Nakada N, Yanagisawa N, Jiang SX, Numata Y, Umezawa A, Miyazaki K, Higashihara M, Murakumo Y.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 105 Issue: 5 Pages: 614-622
- DOI
  10.1007/s12185-016-2173-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K16126, KAKENHI-PROJECT-15H02822
[Journal Article] DNA修復機構をターゲットとした癌の治療戦略2017
- Author(s)
  櫻井靖高、村雲芳樹
- Journal Title
  
  病理と臨床
  
  Volume: 35 Pages: 382-384
- Data Source
  KAKENHI-PROJECT-15H02822
[Journal Article] DNA修復機構をターゲットとした癌の治療戦略2017
- Author(s)
  櫻井靖高、村雲芳樹
- Journal Title
  
  病理と臨床
  
  Volume: 35 Pages: 382-384
- Data Source
  KAKENHI-PROJECT-15K16126
[Journal Article] CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells.2015
- Author(s)
  Jing-Min Zhang, Yoshiki Murakumo, Sumitaka Hagiwara, Ping Jiang, Shinji Mii, Emir Kalyoncu, Shoji Saito, Chikage Suzuki, Yasutaka Sakurai, Yoshiko Numata, Toshimichi Yamamoto, Masahide Takahashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 2 Pages: 252-258
- DOI
  10.1016/j.bbrc.2015.02.093
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670342, KAKENHI-PROJECT-25861926, KAKENHI-PROJECT-15H02822, KAKENHI-PROJECT-25860293
[Journal Article] High expression of REV7 is an independent prognostic indicator in patients with diffuse large B-cell lymphoma treated with rituximab.2015
- Author(s)
  Okina S, Yanagisawa N, Yokoyama M, Sakurai Y, Numata Y, Umezawa A, Higashihara M, Murakumo Y
- Journal Title
  
  Int J Hematol.
  
  Volume: 102 Issue: 6 Pages: 662-669
- DOI
  10.1007/s12185-015-1880-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] 原発性肺腺癌におけるREV7の発現と臨床病理学的因子、予後との関連2023
- Author(s)
  林祥子、一戸昌明、櫻井靖高、村雲芳樹、佐藤之俊
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K06894
[Presentation] 膵臓癌におけるCD109発現の臨床的、細胞生物学的意義の解析2021
- Author(s)
  安達快、櫻井靖高、加藤琢哉、一戸昌明、村雲芳樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 膵癌におけるBRCAnessの臨床病理学的特性および膵癌細胞株における抗癌剤感受性2021
- Author(s)
  蓼原将良、加藤琢哉、安達快、櫻井靖高、一戸昌明、村雲芳樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06973
[Presentation] 膵癌におけるBRCAnessの臨床病理学的特性および膵癌細胞株における抗癌剤感受性2021
- Author(s)
  蓼原将良、加藤琢哉、安達快、櫻井靖高、一戸昌明、村雲芳樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 膵臓癌におけるCD109発現の臨床的、細胞生物学的意義の解析2021
- Author(s)
  安達快、櫻井靖高、加藤琢哉、一戸昌明、村雲芳樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06973
[Presentation] 悪性黒色腫におけるREV7 の機能解析2020
- Author(s)
  星野昭芳、一戸昌明、櫻井靖高、村雲芳樹
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 手術検体を用いた膵癌におけるBRCAnessの解析2020
- Author(s)
  蓼原将良、加藤琢哉、安達快、櫻井靖高、一戸昌明、村雲芳樹
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 膵臓癌の予後におけるCD109 発現の意義の解析2020
- Author(s)
  安達快、櫻井靖高、加藤琢哉、一戸昌明、村雲芳樹
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 小細胞肺癌におけるREV7 発現の生物学的意義2020
- Author(s)
  眞山到、一戸昌明、櫻井靖高、村雲芳樹
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 近位依存性ビオチン標識法による新規REV7 結合タンパク質の同定2020
- Author(s)
  椎名勇貴、櫻井靖高、加藤琢哉、一戸昌明、村雲芳樹
- Organizer
  第７９回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 小細胞肺癌の生物学的特性におけるREV7発現の意義2019
- Author(s)
  眞山到、村雲芳樹、一戸昌明、櫻井靖高
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 生殖細胞維持および精子形成におけるDNA 損傷応答蛋白REV7 の重要性2019
- Author(s)
  磯貝奈々子、櫻井靖高、加藤琢哉、一戸昌明、沼田賀子、梅沢敦子、村雲芳樹
- Organizer
  第１０８回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] 膵臓癌の予後におけるCD109発現の意義の解析2019
- Author(s)
  安達快、櫻井靖高、加藤琢哉、一戸昌明、村雲芳樹
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 手術検体を用いた膵癌におけるBRCAnessの解析2019
- Author(s)
  蓼原将良、加藤琢哉、安達快、櫻井靖高、一戸昌明、村雲芳樹
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 悪性黒色腫におけるREV7の機能解析2019
- Author(s)
  星野昭芳、一戸昌明、櫻井靖高、村雲芳樹
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16616
[Presentation] 生殖細胞維持および精子形成におけるDNA損傷応答蛋白REV7の重要性2019
- Author(s)
  磯貝奈々子、櫻井靖高、加藤琢哉、梅沢敦子、沼田賀子、一戸昌明、吉田松生、村雲芳樹
- Organizer
  第４２回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] GPIアンカー型蛋白CD109の肺扁平上皮癌における発現意義の解析2018
- Author(s)
  村雲芳樹、七浦奈都実、櫻井靖高、一戸昌明
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] Suppression of REV7, the regulatory subunit of Polzeta, sensitizes drug-resistant germ cell tumors to chemotherapy2018
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] Molecular mechanism of transcriptional regulation of REV7, which is involved in the DNA damage tolerance mechanism2018
- Author(s)
  村雲芳樹、櫻井靖高
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] GPIアンカー型蛋白CD109の肺扁平上皮癌細胞における発現意義の解析2018
- Author(s)
  村雲芳樹、七浦奈都実、櫻井靖高、一戸昌明
- Organizer
  第１０７回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] Suppression of REV7, the regulatory subunit of Polz, sensitizes drug-resistant germ cell tumors to chemotherapy2018
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] GPIアンカー型蛋白CD109の肺扁平上皮癌細胞における発現意義の解析2018
- Author(s)
  村雲芳樹、七浦奈都実、櫻井靖高、一戸昌明
- Organizer
  第１０７回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Molecular mechanism of transcriptional regulation of REV7, which is involved in the DNA damage tolerance mechanism2018
- Author(s)
  村雲芳樹、櫻井靖高
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] REV7の発現抑制は抗癌剤抵抗性胚細胞腫瘍のシスプラチン感受性を増強する2018
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第１０７回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02643
[Presentation] REV7の発現抑制は抗癌剤抵抗性胚細胞腫瘍のシスプラチン感受性を増強する2018
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第１０７回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] REV7の発現抑制は抗癌剤抵抗性胚細胞腫瘍のシスプラチン感受性を増強する2018
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] Significance of CD109 expression in lung squamous cell carcinoma cells2017
- Author(s)
  七浦奈都実、櫻井靖高、村雲芳樹
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Depletion of REV7 sensitizes testicular germ cell tumors to chemotherapy2017
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] ヒトREV7の抑制は抗癌剤抵抗性胚細胞腫瘍のシスプラチン感受性を増強する2017
- Author(s)
  櫻井靖高、吉田和樹、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Depletion of REV7 sensitizes testicular germ cell tumors to chemotherapy2017
- Author(s)
  櫻井靖高、仲田典広、高橋雅英、村雲芳樹
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Characterization of the Promoter Region of DNA Repair Protein REV72017
- Author(s)
  島田裕子、櫻井靖高、村雲芳樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] Characterization of the Promoter Region of DNA Repair Protein REV72017
- Author(s)
  島田裕子、櫻井靖高、村雲芳樹
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] GPIアンカー型蛋白CD109の肺扁平上皮癌細胞における発現意義の解析2017
- Author(s)
  七浦奈都実、櫻井靖高、島田裕子、村雲芳樹
- Organizer
  第１０６回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] ヒト REV7の抑制は抗癌剤抵抗性胚細胞腫瘍のシスプラチン感受性を増強する2017
- Author(s)
  櫻井靖高、吉田和樹、仲田典広、高橋雅英、村雲芳樹
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] GPIアンカー型蛋白CD109の肺扁平上皮癌細胞における発現意義の解析2017
- Author(s)
  七浦奈都実、櫻井靖高、島田裕子、村雲芳樹
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] びまん性大細胞性B細胞リンパ腫におけるCD109の発現と機能について（Up-regulation of CD109 expression is associated with prognosis of patients with diffuse large B-cell lymphoma)2016
- Author(s)
  横山真喜、一戸昌明、翁祖誠、櫻井靖高、仲田典広、東原正明、村雲芳樹
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] ヒトREV7の抑制は精巣胚細胞腫瘍のシスプラチン感受性を増強する2016
- Author(s)
  櫻井靖高 , 吉田和樹 , 高橋雅英 , 村雲芳樹
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] High expression of REV7 is an independent prognostic indicator in patients with diffuse large B-cell lymphomatreated with rituximab.2016
- Author(s)
  Sosei Okina, Nobuyuki Yanagisawa, Maki Yokoyama, Yasutaka Sakurai, Yoshiko Numata, Atsuko Umezawa, Masaaki Higashihara, Yoshiki Murakumo.
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Place of Presentation
  Maui (USA)
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] DNA損傷応答蛋白質REV7の遺伝子発現制御の解析（Gene Expression Analysis of DNA Damage Response Protein REV7）2016
- Author(s)
  島田裕子、櫻井靖高、村雲芳樹
- Organizer
  第１０５回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] REV7の抑制は精巣胚細胞腫瘍のDNA損傷に対する感受性を増強する（Suppression of REV7 enhances sensitivity to DNA-damaging treatments in testicular germ cell tumors)2016
- Author(s)
  櫻井靖高、高橋雅英、村雲芳樹
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] 皮膚悪性腫瘍におけるREV7蛋白発現意義の探索（An exploration of the signi cances of REV7 expression in malignant skin tumors）2016
- Author(s)
  中山知佳、蒋世旭、梅沢敦子、櫻井靖高、一戸昌明、仲田典広、村雲芳樹
- Organizer
  第１０５回日本病理学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Suppression of REV7 enhances sensitivity to DNA-damaging treatments in testicular germ cell tumors2016
- Author(s)
  櫻井靖高、高橋雅英、村雲芳樹
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K16126
[Presentation] REV7の抑制は精巣胚細胞腫瘍のシスプラチン感受性を増強する（Suppression of REV7 enhances cisplatin sensitivity in testicular germ cell tumors）2015
- Author(s)
  櫻井靖高、高橋雅英、村雲芳樹
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H02822
[Presentation] Suppression of REV7 enhances cisplatin sensitivity in testicular germ cell tumors2015
- Author(s)
  櫻井靖高、高橋雅英、村雲芳樹
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K16126

1. Murakumo Yoshiki (40324438)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
2. 一戸昌明 (80365163)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
3. 蒋世旭 (70276153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 市原正智 (00314013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 吉田松生 (60294138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NUMATA Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. UMEZAWA Atsuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. KATO Takuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 吉田功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 斎藤成也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山本敏充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 眞山到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 佐藤雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Yasutaka 櫻井 靖高

Research Projects

Research Products

Co-Researchers

新規DNA二本鎖切断修復関連タンパク質によるPARP阻害剤抵抗性メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

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術前化学療法進行胃癌に対する治療効果とDNA修復関連蛋白REV7の発現との関連

Principal Investigator

Project Period (FY)

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Research Institution

DNA損傷トレランスタンパク質REV7を介した紫外線誘発皮膚癌の発生機序の解明Principal Investigator

Principal Investigator

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Research Institution

Elucidation of the function of DNA damage tolerance in UV-induced skin cancer developmentPrincipal Investigator

Principal Investigator

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Elucidation of novel molecular mechanisms for maintenance of spermatogonial stem cells and gametogenesis in the testis

Principal Investigator

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Review Section

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A study on DNA damage tolerance pathways as novel targets for cancer therapyPrincipal Investigator

Principal Investigator

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Research Institution

Involvement of translesion DNA synthesis in the development of UV-induced skin cancer and its possible mechanisms

Principal Investigator

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[Journal Article] REV7 is involved in outcomes of platinum-based chemotherapy in pancreatic cancer via controlling the DNA damage response2024

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[Journal Article] REV7 in Cancer Biology and Management2023

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[Journal Article] Identification of the promoter region regulating the transcription of the REV7 gene2023

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[Journal Article] Clinicopathological Significance of BRCAness in Resectable Pancreatic Ductal Adenocarcinoma and Its Association With Anticancer Drug Sensitivity in Pancreatic Cancer Cells2022

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[Journal Article] CD109 expression in tumor cells and stroma correlates with progression and prognosis in pancreatic cancer2021

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[Journal Article] Upregulation of REV7 correlates with progression of malignant melanoma2021

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[Journal Article] Increased expression of REV7 in small cell lung carcinomas and its association with tumor cell survival and proliferation2020

Author(s)

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Sakurai Yasutaka 櫻井靖高