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Hajime Abe  安部 元

ORCIDConnect your ORCID iD *help
Researcher Number 50746576
Affiliation (based on the past Project Information) *help 2017 – 2018: 東京大学, 医学部附属病院, 登録研究員
2015 – 2016: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field
Principal Investigator
Cardiovascular medicine
Keywords
Principal Investigator
心線維化 / マクロファージ / 心不全 / 低酸素 / 心臓リモデリング / 炎症
  • Research Projects

    (2 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (1 People)
  •  Research for the factor regulating activation of cardiac fibroblastsPrincipal Investigator

    • Principal Investigator
      Abe Hajime
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      The University of Tokyo
  •  The roles of polarization of macrophages in cardiac fibrosisPrincipal Investigator

    • Principal Investigator
      Hajime Abe
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      The University of Tokyo

All 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M2019

    • Author(s)
      Hajime Abe et.al.
    • Journal Title

      Nature Communications

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15990
  • [Journal Article] Planimetry of the Orifice Area in Aortic Valve Stenosis Using Phase-Contrast Cardiac Magnetic Resonance Imaging2018

    • Author(s)
      Abe Hajime、Iguchi Nobuo、Utanohara Yuko、Takada Kaori、Hen Yasuki、Machida Haruhiko、Takeda Norihiko、Sumiyoshi Tetsuya
    • Journal Title

      Int. Heart J.

      Volume: 59 Issue: 1 Pages: 77-80

    • DOI

      10.1536/ihj.16-542

    • NAID

      130006321387

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15990
  • [Journal Article] Planimetry of the orifice area in aortic valve stenosis using phase-contrast cardiac magnetic resonance imaging.2017

    • Author(s)
      Abe H., Iguchi N, Utanohara Y, Takada K, Hen Y, Machida H, Takeda N, Sumiyoshi T.
    • Journal Title

      Int Heart J. 2017 (印刷中)

      Volume: 印刷中

    • NAID

      130006321387

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Journal Article] Distinct Metabolic Phenotypes within Non-small Cell 1 Lung Cancer Define Selective Vulnerability to Glycolytic Inhibition of Lung Squamous Cell Carcinoma.2017

    • Author(s)
      Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, Yoo H, Chen M, Ahn JM, Minna JD, Helke KL, Singh PK, Shackelford DB, Kim JW.
    • Journal Title

      Nature Commun. 2017 (印刷中).

      Volume: 印刷中

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Journal Article] Bevacizumab-Related Microvascular Angina and Its Management with Nicorandil2017

    • Author(s)
      Katoh Manami、Takeda Norihiko、Arimoto Takahide、Abe Hajime、Oda Katsutoshi、Osuga Yutaka、Fujii Tomoyuki、Komuro Issei
    • Journal Title

      Int. Heart J.

      Volume: 58 Issue: 5 Pages: 803-805

    • DOI

      10.1536/ihj.16-537

    • NAID

      130006179206

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15990
  • [Journal Article] The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases2017

    • Author(s)
      Abe Hajime、Semba Hiroaki、Takeda Norihiko
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 24 Issue: 9 Pages: 884-894

    • DOI

      10.5551/jat.RV17009

    • NAID

      130006038428

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15990, KAKENHI-PLANNED-26111003
  • [Journal Article] HIF-1α-PDK1 axis induced active glycolysis plays an essential role in macrophage migratory capacity2016

    • Author(s)
      Hiroaki , Norihiko T, Takayuki I, Yuki S, Kurara H, Masaki W, Hidenobu M, Yoshifumi Y, Masayuki M, Dana J, Hyunsung C, Jung-whan K, Masataka A, Andrew C, Hajime A, Katsura S, Katsuhiro K, Manami K, Keimon S, Nobuhito G, Randall S J, Ichiro M, Ryozo N, and Issei K
    • Journal Title

      Nature Communications

      Volume: In press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Journal Article] HIF-1alpha-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity2016

    • Author(s)
      Semba, H., Takeda, N., Isagawa, T., Sugiura, Y., Honda, K., Wake, M., Miyazawa, H., Yamaguchi, Y., Miura, M., Jenkins, DM., Choi, H., Kim, JW., Asagiri, M., Cowburn, AS., Abe, H., Soma, K., Koyama, K., Katoh, M., Sayama, K., Goda, N., Johnson, RS., Manabe, I., Nagai, R., Komuro, I.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 11635-11635

    • DOI

      10.1038/ncomms11635

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26110005, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-15H04824, KAKENHI-PROJECT-16H06145, KAKENHI-PROJECT-15K19369, KAKENHI-PROJECT-15K19372
  • [Presentation] Roles of Ly6Chi monocytes hypoxia signaling in cardiac remodeling2017

    • Author(s)
      Abe H, Takeda N, Isagawa T, Semba H, Soma K, Koyama K, Wake M, Katoh M, Manabe I, Nagai R, Komuro I
    • Organizer
      Keystone Symposium “Adaptations to Hypoxia in Physiology and Disease”
    • Place of Presentation
      Whistler, British Columbia, Canada
    • Year and Date
      2017-03-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] HIF-1α - Pdk1 axis induced metabolic reprogramming critically regulates macrophage function in inflammatory conditions2016

    • Author(s)
      Semba H, Takeda N, Isagawa T, Wake M, Abe H, Soma K, Koyama K, Katoh M, Manabe I, Nagai R, Takeshi Yamashita and Komuro I
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県・仙台)
    • Year and Date
      2016-02-13
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] 心臓リモデリングにおいてLy6C highマクロファージはHIF-1α-OncostatinMシグナルを介して心保護的に作用する2016

    • Author(s)
      安部 元,武田 憲彦,仙波 宏章,相馬 桂,小山 雄広,和氣 正樹,加藤 愛巳,中釜 悠,真鍋 一郎,永井 良三,小室 一成
    • Organizer
      第20回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      東京コンベンションホール
    • Year and Date
      2016-12-16
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] HIF-1α - PDK1 axis induced active glycolysis plays an essential role in macrophage migratory capacity2016

    • Author(s)
      Takeda N, Semba H, Isagawa T, Abe H, Sugiura Y, Honda K, Wake M, Kim JW, Soma K, Koyama K, Katoh M, Johnson RS, Manabe I, Nagai R and Komuro I
    • Organizer
      Keystone symposium; Immunometabolism in immune function and inflammatory disease
    • Place of Presentation
      Banff (Canada)
    • Year and Date
      2016-02-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] Roles of Ly6Chi monocytes hypoxia signaling in cardiac remodeling2016

    • Author(s)
      Abe H, Takeda N, Semba H, Soma K, Koyama K, Wake M, Katoh M, Manabe I, Nagai R and Komuro I
    • Organizer
      Keystone symposium; Immunometabolism in immune function and inflammatory disease
    • Place of Presentation
      Banff (Canada)
    • Year and Date
      2016-02-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] 圧負荷後心臓リモデリングにおけるマクロファージ低酸素シグナルの役割2016

    • Author(s)
      安部 元, 武田 憲彦, 砂河 孝行, 仙波 宏章, 相馬 桂, 小山 雄広, 和氣 正樹, 加藤 愛巳, 中釜 悠, 真鍋 一郎, 永井 良三, 小室 一成
    • Organizer
      第39回日本高血圧学会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-09-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] Roles of macrophages hypoxia signaling in pressure overload-induced cardiac remodeling2015

    • Author(s)
      Abe H, Takeda N, Semba H, Soma K, Koyama K, Wake M, Katoh M, Manabe I, Nagai R and Komuro I.
    • Organizer
      第32回国際心臓研究学会日本部会
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] Roles of Macrophages Hypoxia Signaling in Pressure Overload Induced Cardiac Remodeling2015

    • Author(s)
      Abe H, Takeda N, Semba H, Soma K, Koyama K, Wake M, Manabe I, Nagai R and Komuro I
    • Organizer
      第79回日本循環器学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2015-04-25
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] M1マクロファージの集積遷延は腫瘍内血管の未熟化を引き起こす2015

    • Author(s)
      相馬桂 武田憲彦 砂河孝行 安部元 仙波宏章 小山雄広 和氣正樹 加藤愛巳 真鍋一郎 永井良三 小室一成
    • Organizer
      第23回日本血管生物医学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2015-12-12
    • Data Source
      KAKENHI-PROJECT-15K19369
  • [Presentation] Perivascular accumulation of M1 macrophages elicits the development of immature vascular formation2015

    • Author(s)
      Soma K, Takeda N, Isagawa T, Abe H, Semba H, Koyama K, Wake M, Manabe I, Nagai R and Komuro I
    • Organizer
      ESC Congress2015
    • Place of Presentation
      London (UK)
    • Year and Date
      2015-09-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19369
  • 1.  YAMAGUCHI Yoshifumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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