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Chaya Taro  茶屋 太郎

ORCIDConnect your ORCID iD *help
Researcher Number 50747087
Other IDs
Affiliation (Current) 2025: 大阪大学, 蛋白質研究所, 准教授
Affiliation (based on the past Project Information) *help 2024: 大阪大学, 蛋白質研究所, 准教授
2020 – 2022: 大阪大学, 蛋白質研究所, 准教授
2018: 大阪大学, 蛋白質研究所, 助教
2015 – 2017: 大阪大学, たんぱく質研究所, 助教
Review Section/Research Field
Principal Investigator
General anatomy (including histology/embryology) / Basic Section 48010:Anatomy-related / Basic Section 48040:Medical biochemistry-related
Keywords
Principal Investigator
繊毛 / マウス / リン酸化 / 繊毛病 / 網膜 / キナーゼ / 脱リン酸化 / ゲノム編集 / タンパク質輸送 / 明順応 … More / 神経節細胞 / 水平細胞 / 明暗順応 / Gたんぱく質 / ユビキチン / 細胞内輸送 / 順応 / 視細胞 / 蝸牛 / 蛋白質輸送 / 聴覚 / 平面内細胞極性 / 内耳 Less
  • Research Projects

    (4 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (6 People)
  •  タンパク質脱リン酸化酵素の解析から迫る繊毛の形成と機能メカニズムの解明Principal Investigator

    • Principal Investigator
      茶屋 太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Osaka University
  •  Elucidation of the molecular mechanisms that regulate protein transport in cilia.Principal Investigator

    • Principal Investigator
      Chaya Taro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Osaka University
  •  Elucidation of the regulatory mechanism underlying light and dark adaptation in retinal photoreceptor cells and its application to retinal protectionPrincipal Investigator

    • Principal Investigator
      CHAYA Taro
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Osaka University
  •  Analysis of the mechanisms underlying cilia formation and their physiological significancePrincipal Investigator

    • Principal Investigator
      Chaya Taro
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis2022

    • Author(s)
      Tsutsumi R, Chaya T, Tsujii T, Furukawa T
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298(3) Issue: 3 Pages: 101686-101686

    • DOI

      10.1016/j.jbc.2022.101686

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J12966, KAKENHI-PROJECT-20K07326, KAKENHI-PROJECT-21H02657
  • [Journal Article] Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation2022

    • Author(s)
      Chaya Taro、Maeda Yamato、Sugimura Ryo、Okuzaki Daisuke、Watanabe Satoshi、Varner Leah R.、Motooka Daisuke、Gyoten Daichi、Yamamoto Haruka、Kato Hidemasa、Furukawa Takahisa
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 9 Pages: 102293-102293

    • DOI

      10.1016/j.jbc.2022.102293

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02657, KAKENHI-PROJECT-20K07326
  • [Journal Article] Broad locations of antigenic regions for anti-TRPM1 autoantibodies in paraneoplastic retinopathy with retinal ON bipolar cell dysfunction2021

    • Author(s)
      Gyoten D, Ueno S, Okado S, Chaya T, Yasuda S, Morimoto T, Kondo M, Kimura K, Hayashi T, Leroy BP, Woo SJ, Mukai R, Joo K, Furukawa T.
    • Journal Title

      Exp Eye Res

      Volume: 212 Pages: 108770-108770

    • DOI

      10.1016/j.exer.2021.108770

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02954, KAKENHI-PROJECT-21H02657, KAKENHI-PROJECT-20K07326, KAKENHI-PROJECT-21K09756
  • [Journal Article] Deficiency of the neurodevelopmental disorder-associated gene <i>Cyfip2</i> alters the retinal ganglion cell properties and visual acuity2021

    • Author(s)
      Chaya Taro、Ishikane Hiroshi、Varner Leah R、Sugita Yuko、Maeda Yamato、Tsutsumi Ryotaro、Motooka Daisuke、Okuzaki Daisuke、Furukawa Takahisa
    • Journal Title

      Human Molecular Genetics

      Volume: 31 Issue: 4 Pages: 535-547

    • DOI

      10.1093/hmg/ddab268

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02657, KAKENHI-PROJECT-20K07326
  • [Journal Article] Post-translational modification enzymes as key regulators of ciliary protein trafficking2021

    • Author(s)
      Chaya Taro、Furukawa Takahisa
    • Journal Title

      The Journal of Biochemistry

      Volume: - Issue: 6 Pages: 633-642

    • DOI

      10.1093/jb/mvab024

    • NAID

      40022686979

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07326, KAKENHI-PROJECT-18H02593, KAKENHI-PROJECT-21H02657
  • [Journal Article] A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia2021

    • Author(s)
      Whittaker D.E., Oleari R, Gregory L.C., Le Q.P., Williams H.J., Torpiano J.G., Formosa N, Cachia M.J., Field D, Lettieri A, Ocaka L.A., Paganoni A.J.J., Rajabali S.H., Riegman K.L.H., De M.L.B., Chaya T, Robinson I.C.A.F., Furukawa T, Cariboni A, Basson M.A, Dattani M.T.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 131 Issue: 24

    • DOI

      10.1172/jci141587

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02657, KAKENHI-PROJECT-20K07326
  • [Journal Article] Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity2021

    • Author(s)
      Kubo Shun、Yamamoto Haruka、Kajimura Naoko、Omori Yoshihiro、Maeda Yamato、Chaya Taro、Furukawa Takahisa
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 4180-4180

    • DOI

      10.1038/s41598-021-83781-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07326, KAKENHI-PROJECT-18H02593, KAKENHI-PROJECT-19H03420, KAKENHI-PROJECT-21H02657
  • [Journal Article] The potential role of Arhgef33 RhoGEF in foveal development in the zebra finch retina2020

    • Author(s)
      Sugiyama Takefumi、Yamamoto Haruka、Kon Tetsuo、Chaya Taro、Omori Yoshihiro、Suzuki Yutaka、Abe Kentaro、Watanabe Dai、Furukawa Takahisa
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 21450-21450

    • DOI

      10.1038/s41598-020-78452-6

    • NAID

      120006952776

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07326, KAKENHI-PROJECT-18H04014, KAKENHI-PROJECT-18H02593
  • [Journal Article] miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation.2019

    • Author(s)
      Kozuka T, Omori Y, Watanabe S, Tarusawa E, Yamamoto H, Chaya T, Furuhashi M, Morita M, Sato T, Hirose S, Ohkawa Y, Yoshimura Y, Hikida T, Furukawa T.
    • Journal Title

      Sci Rep.

      Volume: Mar 5;9(1) Issue: 1 Pages: 3445-3445

    • DOI

      10.1038/s41598-019-38910-2

    • NAID

      120006579467

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07085, KAKENHI-PLANNED-16H06568, KAKENHI-PUBLICLY-18H04802, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K08583, KAKENHI-PROJECT-16K14579, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-17K15548, KAKENHI-PROJECT-19H03420, KAKENHI-PROJECT-18K14611, KAKENHI-PROJECT-18H02547, KAKENHI-PLANNED-16H06460
  • [Journal Article] Enriched expression of the ciliopathy gene Ick in cell proliferating regions of adult mice2018

    • Author(s)
      Tsutsumi R, Chaya T, Furukawa T
    • Journal Title

      Gene Expr. Patterns

      Volume: 29 Pages: 18-23

    • DOI

      10.1016/j.gep.2018.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Journal Article] Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity2018

    • Author(s)
      Ueno Akiko、Omori Yoshihiro、Sugita Yuko、Watanabe Satoshi、Chaya Taro、Kozuka Takashi、Kon Tetsuo、Yoshida Satoyo、Matsushita Kenji、Kuwahara Ryusuke、Kajimura Naoko、Okada Yasushi、Furukawa Takahisa
    • Journal Title

      Cell Reports

      Volume: 22 Issue: 13 Pages: 3548-3561

    • DOI

      10.1016/j.celrep.2018.03.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08583, KAKENHI-PROJECT-17K15548, KAKENHI-PROJECT-15H04669, KAKENHI-PROJECT-26462686, KAKENHI-PROJECT-18K09406, KAKENHI-PROJECT-18K14611
  • [Journal Article] The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit2017

    • Author(s)
      Kozuka Takashi、Chaya Taro、Tamalu Fuminobu、Shimada Mariko、Fujimaki-Aoba Kayo、Kuwahara Ryusuke、Watanabe Shu-Ichi、Furukawa Takahisa
    • Journal Title

      The Journal of Neuroscience

      Volume: 37 Issue: 41 Pages: 9889-9900

    • DOI

      10.1523/jneurosci.0824-17.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08504, KAKENHI-PROJECT-17K15548, KAKENHI-PROJECT-15H04669
  • [Journal Article] Ick ciliary kinase is essential for planar cell polarity formation in inner ear hair cells and hearing function.2017

    • Author(s)
      Okamoto S, Chaya T, Omori Y, Kuwahara R, Kubo S, Sakaguchi H, Furukawa T
    • Journal Title

      Journal of Neuroscience

      Volume: 37 Issue: 8 Pages: 2073-2085

    • DOI

      10.1523/jneurosci.3067-16.2017

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04669, KAKENHI-PROJECT-15K18955, KAKENHI-PROJECT-16K08583
  • [Journal Article] Versatile functional roles of horizontal cells in the retinal circuit2017

    • Author(s)
      Chaya Taro、Matsumoto Akihiro、Sugita Yuko、Watanabe Satoshi、Kuwahara Ryusuke、Tachibana Masao、Furukawa Takahisa
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 5540-5540

    • DOI

      10.1038/s41598-017-05543-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15548, KAKENHI-PROJECT-15H04669
  • [Journal Article] Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity2017

    • Author(s)
      Omori Yoshihiro、Kubo Shun、Kon Tetsuo、Furuhashi Mayu、Narita Hirotaka、Kominami Taro、Ueno Akiko、Tsutsumi Ryotaro、Chaya Taro、Yamamoto Haruka、Suetake Isao、Ueno Shinji、Koseki Haruhiko、Nakagawa Atsushi、Furukawa Takahisa
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 114 Issue: 39

    • DOI

      10.1073/pnas.1707021114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08583, KAKENHI-PROJECT-15K14418, KAKENHI-PROJECT-17K15548, KAKENHI-PROJECT-15H04669
  • [Journal Article] Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport2016

    • Author(s)
      Boubakri M, Chaya T, Hirata H, Kajimura N, Kuwahara R, Ueno A, Malicki J, Furukawa T, Omori Y
    • Journal Title

      J Biol Chem

      Volume: 291 Pages: 24465-24474

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18955
  • [Journal Article] ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles2016

    • Author(s)
      Shibata S, Kawanai T, Hara T, Yamamoto A, Chaya T, Tokuhara Y, Tsuji C, Sakai M, Tachibana T, Inagaki S
    • Journal Title

      J Cell Sci

      Volume: 129 Pages: 3620-3634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K18955
  • [Journal Article] Role of the Mouse Retinal Photoreceptor Ribbon Synapse in Visual Motion Processing for Optokinetic Responses2015

    • Author(s)
      Sugita Y, Araki F, Chaya T, Kawano K, Furukawa T, Miura K
    • Journal Title

      PLOS ONE

      Volume: 印刷中 Issue: 5 Pages: e0124132-e0124132

    • DOI

      10.1371/journal.pone.0124132

    • NAID

      120005745666

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23500467, KAKENHI-PROJECT-15K12129, KAKENHI-PROJECT-15K18955, KAKENHI-PROJECT-24650105
  • [Journal Article] Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control2015

    • Author(s)
      Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0128422-e0128422

    • DOI

      10.1371/journal.pone.0128422

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18955, KAKENHI-PROJECT-25293070
  • [Journal Article] Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse Retina2015

    • Author(s)
      Irie S, Sanuki R, Muranishi Y, Kato K, Chaya T, Furukawa T
    • Journal Title

      Mol Cell Biol

      Volume: 35 Issue: 15 Pages: 2583-2596

    • DOI

      10.1128/mcb.00048-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18955, KAKENHI-PROJECT-15H04669, KAKENHI-PROJECT-26640045
  • [Journal Article] Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice2015

    • Author(s)
      Mizuhashi K, Chaya T, Kanamoto T, Omori Y, Furukawa T
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0133704-e0133704

    • DOI

      10.1371/journal.pone.0133704

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18955, KAKENHI-PROJECT-25293070
  • [Patent] 網膜および/または光受容に関連する症状の改善または予防用医薬ならびに網膜および/または光受容に関連する症状を改善または予防する物質のスクリーニング方法2018

    • Inventor(s)
      古川貴久、茶屋太郎
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-194648
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] Functional analysis of the ciliary protein transport regulating kinase ICK in retinal photoreceptor cells2023

    • Author(s)
      Taro Chaya, Ryotaro Tsutsumi, Yamato Maeda, Takahisa Furukawa
    • Organizer
      the Cold Spring Harbor Asia conference on Cilia & Centrosomes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07326
  • [Presentation] Functional mechanisms of cilia and their roles in sensory perceptions2022

    • Author(s)
      Taro Chaya, Ryotaro Tsutsumi, Takahisa Furukawa
    • Organizer
      第95回日本薬理学会年会 感覚研究コンソーシアム共催シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07326
  • [Presentation] 繊毛内におけるタンパク質輸送制御のメカニズムと生理的意義の解明2020

    • Author(s)
      茶屋 太郎
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07326
  • [Presentation] 繊毛病の発症メカニズム解明と治療法開発を目指して2020

    • Author(s)
      茶屋 太郎
    • Organizer
      感覚研究コンソーシアム 第1回ピッチイベント
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07326
  • [Presentation] 網膜視細胞における繊毛内輸送を介した光受容感度調節メカニズム2018

    • Author(s)
      茶屋太郎, 堤 崚太郞, Leah Rie Varner, 古川貴久
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] Functional roles of the Fragile X Syndrome-related gene in the retina2018

    • Author(s)
      Taro Chaya, Yuko Sugita, Hiroshi Ishikane, Takahisa Furukawa
    • Organizer
      ISER 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] 網膜視細胞における明暗順応制御メカニズム2018

    • Author(s)
      茶屋太郎, 堤 崚太郞, Leah Rie Varner, 前田和, 古川貴久
    • Organizer
      第11回RRM(Retina Research Meeting)
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] 繊毛内輸送制御メカニズムと内耳における役割2018

    • Author(s)
      茶屋太郎
    • Organizer
      第2回感覚器研究イニシアチブ・シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] 網膜における脆弱X症候群関連遺伝子の機能解析2018

    • Author(s)
      茶屋太郎, 杉田祐子, 三草周平, 古川貴久
    • Organizer
      第41回 日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] Roles of retinal horizontal and bipolar cells in visual information processing2017

    • Author(s)
      Taro Chaya, Takahisa Furukawa
    • Organizer
      The 5th Korea-Japan Joint Meeting of Clinical Electrophysiology of Vision
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] TRPM1チャネルの網膜神経回路発達における役割2017

    • Author(s)
      茶屋太郎, 小塚孝司, 田丸文信, 島田真理子, 桒原隆亮, 渡辺修一, 古川貴久
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17K15548
  • [Presentation] 網膜神経回路における水平細胞の生理機能の解析2016

    • Author(s)
      茶屋太郎、松本彰弘、杉田祐子、桒原隆亮、立花政夫、古川貴久
    • Organizer
      第9回Retina Research Meeting
    • Place of Presentation
      JPタワーホール&カンファレンス(東京都千代田区)
    • Data Source
      KAKENHI-PROJECT-15K18955
  • [Presentation] Cooperative role for Rax and Crx in photoreceptor cell maturation and survival2015

    • Author(s)
      Taro Chaya, Shoichi Irie, Rikako Sanuki, Yuki Muranishi, Kimiko Katoh, Takahisa Furukawa
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15K18955
  • [Presentation] 内耳における繊毛局在キナーゼICKの機能解析2015

    • Author(s)
      茶屋太郎、岡本志央、大森義裕、桒原隆亮、坂口博史、古川貴久
    • Organizer
      「包括脳ネットワーク」冬のシンポジウム
    • Place of Presentation
      一橋大学一橋講堂 学術総合センター(東京都千代田区)
    • Year and Date
      2015-12-18
    • Data Source
      KAKENHI-PROJECT-15K18955
  • 1.  TARUSAWA Etsuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  OMORI Yoshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  MIURA Kenichoro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  近藤 峰生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  田丸 文信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  古川 貴久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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