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KOYANO FUMIKA  小谷野 史香

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KOYANO Fumika  小谷野 史香

小谷野 史香  コヤノ フミカ

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Researcher Number 50747681
Other IDs
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 助教
2025: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 研究員
Affiliation (based on the past Project Information) *help 2022 – 2023: 東京医科歯科大学, 難治疾患研究所, 助教
2020 – 2021: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員
2017 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員
2015: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 44010:Cell biology-related / Pathological medical chemistry
Keywords
Principal Investigator
ユビキチン / 蛋白質分解 / ミトコンドリア / ペルオキシソーム / Parkin / マイトファジー / 膜蛋白質 / p97/VCP / オートファジー / PINK1/Parkin … More / PINK1 / リン酸化 / パーキンソン病 / リン酸化ユビキチン Less
  • Research Projects

    (3 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (2 People)
  •  ミトコンドリア選択的分解における新奇オルガネラ間膜蛋白質輸送機構の解析Principal Investigator

    • Principal Investigator
      小谷野 史香
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Tokyo Medical and Dental University
      Tokyo Metropolitan Institute of Medical Science
  •  Substrate specificity of Parkin and the membrane protein communication between organelles.Principal Investigator

    • Principal Investigator
      KOYANO Fumika
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Phosphorylated ubiquitin is critical for mitochondrial quality assurance to inhibit onset of Parkinson's disease.Principal Investigator

    • Principal Investigator
      KOYANO Fumika
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2024 2023 2019 2018 2017 2016 2015

All Journal Article Presentation Book

  • [Book] 別冊・医学のあゆみ2018

    • Author(s)
      小谷野史香、松田憲之
    • Total Pages
      6
    • Publisher
      医歯薬出版株式会社
    • ISBN
    • Data Source
      KAKENHI-PROJECT-18K14708
  • [Journal Article] Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL2019

    • Author(s)
      Koyano Fumika、Yamano Koji、Kosako Hidetaka、Tanaka Keiji、Matsuda Noriyuki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 294 Issue: 26 Pages: 10300-10314

    • DOI

      10.1074/jbc.ra118.006302

    • NAID

      120006959752

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18H02443
  • [Journal Article] Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes2019

    • Author(s)
      Koyano Fumika、Yamano Koji、Kosako Hidetaka、Kimura Yoko、Kimura Mayumi、Fujiki Yukio、Tanaka Keiji、Matsuda Noriyuki
    • Journal Title

      EMBO reports

      Volume: 20 Issue: 12

    • DOI

      10.15252/embr.201947728

    • NAID

      120006942558

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18H02443
  • [Journal Article] Phosphorylated ubiquitin chain is the genuine Parkin receptor.2015

    • Author(s)
      K. Okatsu, F. Koyano, M. Kimura, H. Kosako, Y. Saeki, K. Tanaka and N. Matsuda
    • Journal Title

      The Journal of Cell Biology

      Volume: 209 Issue: 1 Pages: 111-128

    • DOI

      10.1083/jcb.201410050

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
  • [Journal Article] Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.2015

    • Author(s)
      Koji Yamano, Bruno B. Queliconi, Fumika Koyano, Yasushi Saeki, Takatsugu Hirokawa, Keiji Tanaka§,and Noriyuki Matsuda
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 290 Issue: 42 Pages: 25199-25211

    • DOI

      10.1074/jbc.m115.671446

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
  • [Journal Article] Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria2015

    • Author(s)
      Fumika Koyano; Noriyuki Matsuda
    • Journal Title

      BBA - Molecular Cell Research

      Volume: 1853 Issue: 10 Pages: 2791-2796

    • DOI

      10.1016/j.bbamcr.2015.02.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] p97/VCP-FAF2はペルオキシソームの品質管理を担う(仮題)2024

    • Author(s)
      小谷野史香、山野晃史、小迫英尊、藤木幸夫、田中啓二、松田憲之
    • Organizer
      第47回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06161
  • [Presentation] p97/VCP-FAF2はペルオキシソームの分解を制御する2023

    • Author(s)
      小谷野史香、山野晃史、小迫英尊、藤木幸夫、田中啓二、松田憲之
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06161
  • [Presentation] Parkinが初期損傷ミトコンドリアに移行するメカニズム2019

    • Author(s)
      小谷野史香
    • Organizer
      ミトコンドリアサイエンスワークショップ2019
    • Data Source
      KAKENHI-PROJECT-18K14708
  • [Presentation] MITOL/March5 moves to peroxisomes in mitophagy2019

    • Author(s)
      小谷野史香
    • Organizer
      オルガネラ研究会
    • Data Source
      KAKENHI-PROJECT-18K14708
  • [Presentation] Parkinは損傷ミトコンドリアの選択的除去を仲介しMITOL/March5をペルオキシソームに移行させる2019

    • Author(s)
      小谷野史香
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K14708
  • [Presentation] Parkin with low substrate specificity facilitates labeling of damaged mitochondria for elimination2018

    • Author(s)
      小谷野 史香
    • Organizer
      YoungMito2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14708
  • [Presentation] Parkin機能喪失に由来するパーキンソン病モデルマウスの作製と解析2017

    • Author(s)
      平石萌、小谷野史香、久永眞市、中田和人、田中啓二、松田憲之
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] ミトコンドリア品質管理不全から読み解く遺伝性パーキンソニズム発症の分子機構2016

    • Author(s)
      小谷野史香
    • Organizer
      パーキンソン病と神経科学研究会
    • Place of Presentation
      京都ホテルオークラ(京都府・京都市)
    • Year and Date
      2016-07-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] Familial Parkinson’s disease and Mitochondrial quality control2016

    • Author(s)
      Fumika Koyano
    • Organizer
      第2回4大学1研合同研究会
    • Place of Presentation
      ホテル京都エミナース(京都府・京都市)
    • Year and Date
      2016-01-11
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] 未定2016

    • Author(s)
      Fumika Koyano
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] A screening mechanism for high-quality mitochondria by phosphorylated ubiquitin2016

    • Author(s)
      Fumika Koyano
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] PINK1 PHOSPHORYLATED UBIQUITIN IS A PARKIN ACTIVATOR2015

    • Author(s)
      Fumika Koyano
    • Organizer
      ISN-APSN-ANS 2015 Meeting
    • Place of Presentation
      ケアンズ(オーストラリア)
    • Year and Date
      2015-08-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19037
  • [Presentation] PINK1によってリン酸化されたユビキチンがParkinの活性を制御する2015

    • Author(s)
      小谷野史香
    • Organizer
      YoungMito2015
    • Place of Presentation
      ホテル一宮シーサイドオーツカ(千葉・一宮町)
    • Year and Date
      2015-07-09
    • Data Source
      KAKENHI-PROJECT-15K19037
  • 1.  MATSUDA Noriyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  小迫 英尊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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