UCAR HASAN ウチャルハサン

Researcher Number	50748423
Other IDs
Affiliation (based on the past Project Information) *help	2023: 東京大学, 大学院医学系研究科(医学部), 特任研究員 2021 – 2023: 東京大学, ニューロインテリジェンス国際研究機構, 特任助教 2020: 東京大学, ニューロインテリジェンス国際研究機構, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related Except Principal Investigator Medium-sized Section 46:Neuroscience and related fields / Broad Section G
Keywords	Principal Investigator Glutamate release / SNARE assembly / Synaptic plasticity / Mechanosensation / Spine enlargement / FRET / iGluSnFr / Optogenetics / Release probabilty / mechanobiology … More / mechanical stimulation / Presynaptic terminal / SV mobility / mechanical transmission / PREST / presynaptic plasticity … More Except Principal Investigator スパイン / 学習・記憶 / メカノバイオロジー / 学習 / シナプス / 神経回路 / 知能 / 情動 / 学習記憶 / アクチン繊維 / 作業記憶 / 記憶 / シナプス化学遺伝学 / スパインシナプス / 樹状突起スパイン / 精神疾患 Less

Discovery and characterization of a pressure sensation and transduction (PREST) mechanism in the presynaptic terminal in the CNS.Principal Investigator
- Principal Investigator
  
  UCAR HASAN
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
From the structure-function relationship of dendrtic spines to synaptic mechanobiology
- Principal Investigator
  
  河西春郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  The University of Tokyo
From structural plasticity of dendritic spines to synaptic mechano-biology
- Principal Investigator
  
  河西春郎
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Mechanical transmission at spine synapses: Short-term potentiation and working memory2023
- Author(s)
  Haruo Kasai, Hasan Ucar, Yuichi Morimoto, Fumihiro Eto, Hitoshi Okazaki
- Journal Title
  
  Current Opinion in Neurobiology
  
  Volume: 80 Pages: 102706-102706
- DOI
  10.1016/j.conb.2023.102706
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203, KAKENHI-PROJECT-20H05685
[Journal Article] Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis2021
- Author(s)
  Ucar Hasan、Watanabe Satoshi、Noguchi Jun、Morimoto Yuichi、Iino Yusuke、Yagishita Sho、Takahashi Noriko、Kasai Haruo
- Journal Title
  
  Nature
  
  Volume: 600 Issue: 7890 Pages: 686-689
- DOI
  10.1038/s41586-021-04125-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05176, KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21H02594, KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-21K15203
[Journal Article] Forceful synapses reveal mechanical interactions in the brain.2021
- Author(s)
  Kasai, H. & Ucar, H.
- Journal Title
  
  Nature
  
  Volume: 600 Pages: 2021-2021
- DOI
  10.1038/d41586-021-03516-0
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05685, KAKENHI-PROJECT-21K15203
[Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS2022
- Author(s)
  Ucar Hasan
- Organizer
  Japan Neuroscience Society Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203
[Presentation] Mechanosensing of the enlargement of dendritic spines by presynaptic terminals in rat hippocampus2022
- Author(s)
  Ucar Hasan
- Organizer
  MBSJ 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203
[Presentation] Mechanical actions of dendritic-spine enlargement on the presynaptic terminal & the discovery of the Pressure Sensation and Transduction (PREST) mechanism2022
- Author(s)
  Ucar Hasan
- Organizer
  FENS Forum 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203
[Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS.2022
- Author(s)
  Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., Takahashi, N., Kasai, H.
- Organizer
  JNS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05685
[Presentation] Mechanosensation and PREST in the presynaptic terminals2022
- Author(s)
  Hasan Ucar, Satoshi Watanabe, Jun Noguchi, Sho Yagishita, Yuichiro Morimoto, Noriko Takahashi, Haruo Kasai
- Organizer
  The 45th Annual Meeting of the Japan Neuroscience Society. The 65th Annual Meeting of the Japanese Society for Neurochemistry The 32nd Annual Conference of the Japanese Neural Network Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203
[Presentation] Presynaptic terminals can sense spine enlargement and mechanical pressure to provide stronger synaptic transmission2021
- Author(s)
  Hasan Ucar, Satoshi Watanabe, Jun Noguchi, Sho Yagishita, Yuichiro Morimoto, Noriko Takahashi, Haruo Kasai
- Organizer
  The 44th Annual Meeting of the Japan Neuroscience Society. The 1st CJK International Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15203
[Presentation] Mechanical action of spine enlargement on presynaptic exocytosis2020
- Author(s)
  Hasan UCAR
- Organizer
  Science Salon, IRCN, University of Tokyo
- Data Source
  KAKENHI-PROJECT-20H00480
[Presentation] Potentiation of presynaptic functions by mechanosensing the spine enlargement in rat hippocampus.2020
- Author(s)
  Ucar, H., Watanabe, S., Noguchi, J., Yagishita, S., , Morimoto, Y., Takahashi, N., Kasai, H.
- Organizer
  FENS (Glasgow online).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05685

1. 河西春郎 (60224375)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 柳下祥 (50721940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results

UCAR HASAN ウチャル ハサン

Research Projects

Research Products

Co-Researchers

Discovery and characterization of a pressure sensation and transduction (PREST) mechanism in the presynaptic terminal in the CNS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From the structure-function relationship of dendrtic spines to synaptic mechanobiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From structural plasticity of dendritic spines to synaptic mechano-biology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mechanical transmission at spine synapses: Short-term potentiation and working memory2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Forceful synapses reveal mechanical interactions in the brain.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS2022

Author(s)

Organizer

Data Source

[Presentation] Mechanosensing of the enlargement of dendritic spines by presynaptic terminals in rat hippocampus2022

Author(s)

Organizer

Data Source

[Presentation] Mechanical actions of dendritic-spine enlargement on the presynaptic terminal & the discovery of the Pressure Sensation and Transduction (PREST) mechanism2022

Author(s)

Organizer

Data Source

[Presentation] Mechanical actions of dendritic-spine enlargement and the discovery of the PREST mechanism in the presynaptic terminals in the CNS.2022

Author(s)

Organizer

Data Source

[Presentation] Mechanosensation and PREST in the presynaptic terminals2022

Author(s)

Organizer

Data Source

[Presentation] Presynaptic terminals can sense spine enlargement and mechanical pressure to provide stronger synaptic transmission2021

Author(s)

Organizer

Data Source

[Presentation] Mechanical action of spine enlargement on presynaptic exocytosis2020

Author(s)

Organizer

Data Source

[Presentation] Potentiation of presynaptic functions by mechanosensing the spine enlargement in rat hippocampus.2020

Author(s)

Organizer

Data Source

UCAR HASAN ウチャルハサン