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Hori Kazuya  堀 一也

ORCIDConnect your ORCID iD *help
Researcher Number 50749059
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2023: 福井大学, 学術研究院医学系部門, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49010:Pathological biochemistry-related / Tumor biology
Except Principal Investigator
Basic Section 49030:Experimental pathology-related / Basic Section 48040:Medical biochemistry-related
Keywords
Principal Investigator
大腸癌 / 腫瘍学 / CDX2 / CDX1 / 化学療法薬 / BET阻害薬 / 転写調節CDK阻害薬 / 癌幹細胞性 / 抗がん薬 / CDK阻害薬 … More / 転写CDK / がん幹細胞性 / 大腸がん / LGR5 / 癌幹細胞 / シグナル伝達 / Notchシグナル … More
Except Principal Investigator
PAF1 / 大腸癌 / 癌幹細胞 / 転写機構 / PAF1複合体 / β-cateninタンパク質 / がん幹細胞性 / 大腸がん / ホメオボックス蛋白質 / 腸炎 / 腸管粘膜 / オートファジー / ATG7 / CDX2 / 腸管上皮細胞 / クローン病 / 炎症性腸疾患 Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (1 People)
  •  Control of colon cancer stemness by PAF1 complex

    • Principal Investigator
      青木 耕史
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      University of Fukui
  •  Suppression of colorectal cancer stemness by transcription-related CDK inhibitorsPrincipal Investigator

    • Principal Investigator
      Hori Kazuya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      University of Fukui
  •  Intestinal mucosal barrier by homeobox protein CDX2

    • Principal Investigator
      Aoki Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      University of Fukui
  •  Suppression of colon cancer stemness by caudal-related homeobox transcription factors CDX1 and CDX2Principal Investigator

    • Principal Investigator
      Kazuya Hori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      University of Fukui
  •  Mechanism of suppression of Notch signaling by CDX1 and CDX2 in colon cancer cellsPrincipal Investigator

    • Principal Investigator
      Hori Kazuya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      University of Fukui

All 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Blocking LC3 lipidation and ATG12 conjugation reactions by ATG7 mutant protein containing C572S2019

    • Author(s)
      Nitta A, Hori K, Tanida I, Igarashi A, Deyama Y, Ueno T, Kominami E, Sugai M, Aoki K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 508(2) Issue: 2 Pages: 521-526

    • DOI

      10.1016/j.bbrc.2018.11.158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06928, KAKENHI-PROJECT-18K06955, KAKENHI-PROJECT-18K19423, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-15K12749, KAKENHI-PROJECT-16K15232
  • [Journal Article] RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD12017

    • Author(s)
      Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba‐Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF
    • Journal Title

      The EMBO Journal

      Volume: 36 Issue: 21 Pages: 3232-3249

    • DOI

      10.15252/embj.201796525

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18415
  • [Presentation] Suppression of intestinal cancer stemness and malignant progression by intestine-specific homeoproteins CDX1 and CDX22018

    • Author(s)
      Kazuya Hori, Mako Nakaya, Takanori Goi, Akio Yamaguchi, Shunichiro Iemura, Tohru Natsume, Makoto M. Taketo, Manabu Sugai, Koji Aoki
    • Organizer
      Looking to the future of Developmental Cell Biology Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06955
  • [Presentation] Suppression of intestinal cancer stemness and malignant progression by homeoproteins CDX1 and CDX22017

    • Author(s)
      Aoki K, Hori K
    • Organizer
      日本薬学会北陸支部第129回例会
    • Data Source
      KAKENHI-PROJECT-16K18415
  • [Presentation] Enhanced intestinal mucosal barrier function by homeoprotein CDX2 through autophagy2016

    • Author(s)
      Koji Aoki, Mako Nakaya, Kazuya Hori, Katsuya Okawa, Isei Tanida, Taira Kobayashi, Hitomi Mimuro, Takahito Sanada, Chihiro Sasakawa, Makoto M. Taketo, Manabu Sugai
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K18415
  • [Presentation] Suppression of intestinal cancer stemness and malignant progression by intestine-specific homeoproteins CDX1 and CDX22016

    • Author(s)
      Kazuya Hori, Mako Nakaya, Takanori Goi, Akio Yamaguchi, Shunichiro Iemura, Tohru Natsume, Makoto M. Taketo, Manabu Sugai, Koji Aoki
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K18415
  • [Presentation] Blocking intestinal cancer stemness and malignant progression by intestine-specific homeoproteins CDX1 and CDX22016

    • Author(s)
      Koji Aoki, Kazuya Hori
    • Organizer
      第3回北陸エピジェネティクス研究会
    • Place of Presentation
      AOSSA(福井県福井市)
    • Year and Date
      2016-11-21
    • Data Source
      KAKENHI-PROJECT-16K18415
  • 1.  Aoki Koji (40402862)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results

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